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Karam F. Soliman

TitleAssociate Dean, Office of Research Administration
Faculty RankDistinguished Professor
InstitutionFlorida A&M University
DepartmentCoPPS, IPH Pharmaceutical Sciences
Address1415 S Martin Luther King Jr Blvd
G-134G & G134H East Wing
Tallahassee FL 32307
Phone8505993306
Fax8505993667
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Ferguson DT, Taka E, Messeha S, Flores-Rozas H, Reed SL, Redmond BV, Soliman KFA, Kanga KJW, Darling-Reed SF. The Garlic Compound, Diallyl Trisulfide, Attenuates Benzo[a]Pyrene-Induced Precancerous Effect through Its Antioxidant Effect, AhR Inhibition, and Increased DNA Repair in Human Breast Epithelial Cells. Nutrients. 2024 Jan 19; 16(2). PMID: 38276538.
      Citations:    Fields:    Translation:HumansAnimalsCells
    2. Ferguson DT, Taka E, Tilghman SL, Womble T, Redmond BV, Gedeon S, Flores-Rozas H, Reed SL, Soliman KFA, Kanga KJW, Darling-Reed SF. The Anticancer Effects of the Garlic Organosulfide Diallyl Trisulfide through the Attenuation of B[a]P-Induced Oxidative Stress, AhR Expression, and DNA Damage in Human Premalignant Breast Epithelial (MCF-10AT1) Cells. Int J Mol Sci. 2024 Jan 11; 25(2). PMID: 38255999.
      Citations:    Fields:    Translation:HumansAnimals
    3. Ahmed SA, Mendonca P, Messeha SS, Oriaku ET, Soliman KFA. The Anticancer Effects of Marine Carotenoid Fucoxanthin through Phosphatidylinositol 3-Kinase (PI3K)-AKT Signaling on Triple-Negative Breast Cancer Cells. Molecules. 2023 Dec 21; 29(1). PMID: 38202644.
      Citations:    Fields:    Translation:HumansCells
    4. Ahmed SA, Mendonca P, Messeha SS, Soliman KFA. Anticancer Effects of Fucoxanthin through Cell Cycle Arrest, Apoptosis Induction, and Angiogenesis Inhibition in Triple-Negative Breast Cancer Cells. Molecules. 2023 Sep 09; 28(18). PMID: 37764312.
      Citations: 2     Fields:    Translation:Humans
    5. Mazzio E, Barnes A, Badisa R, Council S, Soliman KFA. Plants against cancer: the immune-boosting herbal microbiome: not of the plant, but in the plant. Basic concepts, introduction, and future resource for vaccine adjuvant discovery. Front Oncol. 2023; 13:1180084. PMID: 37588095.
      Citations:    
    6. Evans JA, Mendonca P, Soliman KFA. Involvement of Nrf2 Activation and NF-kB Pathway Inhibition in the Antioxidant and Anti-Inflammatory Effects of Hesperetin in Activated BV-2 Microglial Cells. Brain Sci. 2023 Jul 29; 13(8). PMID: 37626501.
      Citations:    
    7. Messeha SS, Noel S, Zarmouh NO, Womble T, Latinwo LM, Soliman KFA. Involvement of AKT/PI3K Pathway in Sanguinarine's Induced Apoptosis and Cell Cycle Arrest in Triple-negative Breast Cancer Cells. Cancer Genomics Proteomics. 2023 Jul-Aug; 20(4):323-342. PMID: 37400144.
      Citations:    Fields:    Translation:HumansCells
    8. Barber K, Mendonca P, Evans JA, Soliman KFA. Antioxidant and Anti-Inflammatory Mechanisms of Cardamonin through Nrf2 Activation and NF-kB Suppression in LPS-Activated BV-2 Microglial Cells. Int J Mol Sci. 2023 Jun 29; 24(13). PMID: 37446045.
      Citations: 2     Fields:    Translation:HumansCells
    9. Adinew GM, Messeha S, Taka E, Mochona B, Redda KK, Soliman KFA. Thymoquinone Inhibition of Chemokines in TNF-a-Induced Inflammatory and Metastatic Effects in Triple-Negative Breast Cancer Cells. Int J Mol Sci. 2023 Jun 08; 24(12). PMID: 37373025.
      Citations: 1     Fields:    Translation:HumansCells
    10. Kanga KJW, Kanga LHB, Mendonca P, Soliman KFA, Ferguson DT, Reed SL, Darling-Reed S. Attenuative Effect of Diallyl Trisulfide on Caspase Activity in TNF-a-induced Triple Negative Breast Cancer Cells. Anticancer Res. 2023 Jun; 43(6):2393-2405. PMID: 37247921.
      Citations:    Fields:    Translation:HumansCells
    11. Buxbaum SG, Arigbede O, Mathis A, Close F, Suther SG, Mazzio E, Saunders-Jones R, Soliman KFA, Darling-Reed SF. Disparities in Infant Nutrition: WIC Participation and Rates of Breastfeeding in Florida. Int J Environ Res Public Health. 2023 05 29; 20(11). PMID: 37297592.
      Citations: 1     Fields:    Translation:Humans
    12. Adinew GM, Messeha S, Taka E, Ahmed SA, Soliman KFA. The Role of Apoptotic Genes and Protein-Protein Interactions in Triple-negative Breast Cancer. Cancer Genomics Proteomics. 2023 May-Jun; 20(3):247-272. PMID: 37093683.
      Citations: 1     Fields:    Translation:Humans
    13. Payne A, Taka E, Adinew GM, Soliman KFA. Molecular Mechanisms of the Anti-Inflammatory Effects of Epigallocatechin 3-Gallate (EGCG) in LPS-Activated BV-2 Microglia Cells. Brain Sci. 2023 Apr 07; 13(4). PMID: 37190597.
      Citations:    
    14. Barber K, Mendonca P, Soliman KFA. The Neuroprotective Effects and Therapeutic Potential of the Chalcone Cardamonin for Alzheimer's Disease. Brain Sci. 2023 Jan 14; 13(1). PMID: 36672126.
      Citations:    
    15. Ahmed SA, Mendonca P, Elhag R, Soliman KFA. Anticancer Effects of Fucoxanthin through Cell Cycle Arrest, Apoptosis Induction, Angiogenesis Inhibition, and Autophagy Modulation. Int J Mol Sci. 2022 Dec 17; 23(24). PMID: 36555740.
      Citations: 9     Fields:    Translation:Humans
    16. Adinew GM, Messeha SS, Taka E, Badisa RB, Soliman KFA. Anticancer Effects of Thymoquinone through the Antioxidant Activity, Upregulation of Nrf2, and Downregulation of PD-L1 in Triple-Negative Breast Cancer Cells. Nutrients. 2022 Nov 13; 14(22). PMID: 36432484.
      Citations: 3     Fields:    Translation:HumansCells
    17. Adinew GM, Messeha S, Taka E, Soliman KFA. The Prognostic and Therapeutic Implications of the Chemoresistance Gene BIRC5 in Triple-Negative Breast Cancer. Cancers (Basel). 2022 Oct 22; 14(21). PMID: 36358602.
      Citations:    
    18. Park M, Darwish AG, Elhag RI, Tsolova V, Soliman KFA, El-Sharkawy I. A multi-locus genome-wide association study reveals the genetics underlying muscadine antioxidant in berry skin. Front Plant Sci. 2022; 13:969301. PMID: 35991419.
      Citations:    
    19. Messeha SS, Zarmouh NO, Antonie L, Soliman KFA. Sanguinarine Inhibition of TNF-a-Induced CCL2, IKBKE/NF-?B/ERK1/2 Signaling Pathway, and Cell Migration in Human Triple-Negative Breast Cancer Cells. Int J Mol Sci. 2022 Jul 28; 23(15). PMID: 35955463.
      Citations: 5     Fields:    Translation:HumansCells
    20. Evans JA, Mendonca P, Soliman KFA. Neuroprotective Effects and Therapeutic Potential of the Citrus Flavonoid Hesperetin in Neurodegenerative Diseases. Nutrients. 2022 May 26; 14(11). PMID: 35684025.
      Citations: 15     Fields:    Translation:HumansAnimals
    21. Adinew GM, Messeha SS, Taka E, Badisa RB, Antonie LM, Soliman KFA. Thymoquinone Alterations of the Apoptotic Gene Expressions and Cell Cycle Arrest in Genetically Distinct Triple-Negative Breast Cancer Cells. Nutrients. 2022 May 19; 14(10). PMID: 35631261.
      Citations: 5     Fields:    Translation:HumansCells
    22. Heyliger SO, Soliman KFA, Saulsbury MD, Reams RR. Prognostic Relevance of ZNF844 and Chr 19p13.2 KRAB-Zinc Finger Proteins in Clear Cell Renal Carcinoma. Cancer Genomics Proteomics. 2022 May-Jun; 19(3):305-327. PMID: 35430565.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    23. Adinew G, Messeha SS, Badisa R, Taka E, Soliman KFA. Thymoquinone Anticancer Effects Through the Upregulation of NRF2 and the Downregulation of PD-L1 in MDA-MB-231 Triple-Negative Breast Cancer Cells. FASEB J. 2022 05; 36 Suppl 1. PMID: 35723877.
      Citations: 6     Fields:    Translation:HumansCells
    24. Payne A, Nahashon S, Taka E, Adinew GM, Soliman KFA. Epigallocatechin-3-Gallate (EGCG): New Therapeutic Perspectives for Neuroprotection, Aging, and Neuroinflammation for the Modern Age. Biomolecules. 2022 02 25; 12(3). PMID: 35327563.
      Citations: 33     Fields:    Translation:Humans
    25. Ismail A, Darwish AG, Park M, Gajjar P, Tsolova V, Soliman KFA, El-Sharkawy I. Transcriptome Profiling During Muscadine Berry Development Reveals the Dynamic of Polyphenols Metabolism. Front Plant Sci. 2021; 12:818071. PMID: 35185966.
      Citations:    
    26. Messeha SS, Nezami MA, Hager S, Soliman KFA. A Rare Presentation of a Non-Asian Female With Metastatic Non-small-cell Lung Cancer Harboring EGFR L747P Mutation With Clinical Response to Multi-targeted Epigenetic and EGFR Inhibition. Anticancer Res. 2022 Jan; 42(1):441-447. PMID: 34969754.
      Citations:    Fields:    Translation:Humans
    27. Adinew GM, Taka E, Mochona B, Badisa RB, Mazzio EA, Elhag R, Soliman KFA. Therapeutic Potential of Thymoquinone in Triple-Negative Breast Cancer Prevention and Progression through the Modulation of the Tumor Microenvironment. Nutrients. 2021 Dec 25; 14(1). PMID: 35010954.
      Citations: 9     Fields:    Translation:Humans
    28. Kanga KJW, Mendonca P, Soliman KFA, Ferguson DT, Darling-Reed SF. Effect of Diallyl Trisulfide on TNF-a-induced CCL2/MCP-1 Release in Genetically Different Triple-negative Breast Cancer Cells. Anticancer Res. 2021 Dec; 41(12):5919-5933. PMID: 34848446.
      Citations: 5     Fields:    Translation:HumansCells
    29. Mazzio E, Mack N, Badisa RB, Soliman KFA. Triple Isozyme Lactic Acid Dehydrogenase Inhibition in Fully Viable MDA-MB-231 Cells Induces Cytostatic Effects That Are Not Reversed by Exogenous Lactic Acid. Biomolecules. 2021 11 24; 11(12). PMID: 34944395.
      Citations: 2     Fields:    Translation:HumansCells
    30. Das PR, Darwish AG, Ismail A, Haikal AM, Gajjar P, Balasubramani SP, Sheikh MB, Tsolova V, Soliman KFA, Sherif SM, El-Sharkawy I. Diversity in blueberry genotypes and developmental stages enables discrepancy in the bioactive compounds, metabolites, and cytotoxicity. Food Chem. 2022 Apr 16; 374:131632. PMID: 34823937.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    31. Mazzio E, Almalki A, Darling-Reed SF, Soliman KFA. Effects of Wild Yam Root (Dioscorea villosa) Extract on the Gene Expression Profile of Triple-negative Breast Cancer Cells. Cancer Genomics Proteomics. 2021 Nov-Dec; 18(6):735-755. PMID: 34697066.
      Citations: 1     Fields:    Translation:HumansAnimals
    32. Pajarillo E, Digman A, Nyarko-Danquah I, Son DS, Soliman KFA, Aschner M, Lee E. Astrocytic transcription factor REST upregulates glutamate transporter EAAT2, protecting dopaminergic neurons from manganese-induced excitotoxicity. J Biol Chem. 2021 12; 297(6):101372. PMID: 34756885.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    33. Darling-Reed SF, Nkrumah-Elie Y, Ferguson DT, Flores-Rozas H, Mendonca P, Messeha S, Hudson A, Badisa RB, Tilghman SL, Womble T, Day A, Jett M, Hammamieh R, Soliman KFA. Diallyl Sulfide Attenuation of Carcinogenesis in Mammary Epithelial Cells through the Inhibition of ROS Formation, and DNA Strand Breaks. Biomolecules. 2021 09 06; 11(9). PMID: 34572526.
      Citations: 3     Fields:    Translation:HumansCells
    34. Heyliger SO, Soliman KFA, Saulsbury MD, Reams RR. The Identification of Zinc-Finger Protein 433 as a Possible Prognostic Biomarker for Clear-Cell Renal Cell Carcinoma. Biomolecules. 2021 08 12; 11(8). PMID: 34439859.
      Citations: 6     Fields:    Translation:Humans
    35. Gangapuram M, Mazzio EA, Redda KK, Soliman KFA. Transcriptome Profile Analysis of Triple-Negative Breast Cancer Cells in Response to a Novel Cytostatic Tetrahydroisoquinoline Compared to Paclitaxel. Int J Mol Sci. 2021 Jul 19; 22(14). PMID: 34299315.
      Citations: 2     Fields:    Translation:HumansCells
    36. Messeha SS, Zarmouh NO, Soliman KFA. Polyphenols Modulating Effects of PD-L1/PD-1 Checkpoint and EMT-Mediated PD-L1 Overexpression in Breast Cancer. Nutrients. 2021 May 19; 13(5). PMID: 34069461.
      Citations: 8     Fields:    Translation:HumansCells
    37. Mack N, Mazzio E, Badisa R, Soliman KFA. Metabolic Response to the Mitochondrial Toxin 1-Methyl-4-phenylpyridinium (MPP+) in LDH-A/B Double-knockout LS174T Colon Cancer Cells. Cancer Genomics Proteomics. 2021 May-Jun; 18(3 Suppl):385-405. PMID: 33994363.
      Citations:    Fields:    Translation:Humans
    38. Adinew GM, Taka E, Mendonca P, Messeha SS, Soliman KFA. The Anticancer Effects of Flavonoids through miRNAs Modulations in Triple-Negative Breast Cancer. Nutrients. 2021 Apr 07; 13(4). PMID: 33916931.
      Citations: 12     Fields:    Translation:Humans
    39. Agharahimi M, Badisa RB, Mazzio E, Soliman KF, Goodman CB. Cocaine potentiates an inflammatory response in C6 astroglia-like cells. Biomed Rep. 2021 May; 14(5):45. PMID: 33786174.
      Citations:    
    40. Mendonca P, Alghamdi S, Messeha S, Soliman KFA. Pentagalloyl glucose inhibits TNF-a-activated CXCL1/GRO-a expression and induces apoptosis-related genes in triple-negative breast cancer cells. Sci Rep. 2021 03 11; 11(1):5649. PMID: 33707603.
      Citations: 5     Fields:    Translation:HumansCells
    41. Hedges JR, Soliman KFA, Southerland WM, D'Amour G, Fern?ndez-Repollet E, Khan SA, Kumar D, Shikuma CM, Rivers BM, Yates CC, Yanagihara R, Thompson WE, Bond VC, Harris-Hooker S, McClure SA, Ofili EO. Strengthening and Sustaining Inter-Institutional Research Collaborations and Partnerships. Int J Environ Res Public Health. 2021 03 08; 18(5). PMID: 33800316.
      Citations: 3     Fields:    Translation:Humans
    42. Nyarko-Danquah I, Pajarillo E, Digman A, Soliman KFA, Aschner M, Lee E. Manganese Accumulation in the Brain via Various Transporters and Its Neurotoxicity Mechanisms. Molecules. 2020 Dec 12; 25(24). PMID: 33322668.
      Citations: 18     Fields:    Translation:HumansAnimals
    43. Messeha SS, Zarmouh NO, Asiri A, Soliman KFA. Gene Expression Alterations Associated with Oleuropein-Induced Antiproliferative Effects and S-Phase Cell Cycle Arrest in Triple-Negative Breast Cancer Cells. Nutrients. 2020 Dec 07; 12(12). PMID: 33297339.
      Citations: 16     Fields:    Translation:HumansCells
    44. Hilliard A, Mendonca P, Russell TD, Soliman KFA. The Protective Effects of Flavonoids in Cataract Formation through the Activation of Nrf2 and the Inhibition of MMP-9. Nutrients. 2020 Nov 27; 12(12). PMID: 33261005.
      Citations: 19     Fields:    Translation:Humans
    45. Mazzio E, Badisa R, Mack N, Cassim S, Zdralevic M, Pouyssegur J, Soliman KFA. Whole-transcriptome Analysis of Fully Viable Energy Efficient Glycolytic-null Cancer Cells Established by Double Genetic Knockout of Lactate Dehydrogenase A/B or Glucose-6-Phosphate Isomerase. Cancer Genomics Proteomics. 2020 Sep-Oct; 17(5):469-497. PMID: 32859627.
      Citations: 5     Fields:    Translation:HumansCells
    46. Messeha SS, Zarmouh NO, Asiri A, Soliman KFA. Rosmarinic acid-induced apoptosis and cell cycle arrest in triple-negative breast cancer cells. Eur J Pharmacol. 2020 Oct 15; 885:173419. PMID: 32750370.
      Citations: 26     Fields:    Translation:HumansCells
    47. Mendonca P, Soliman KFA. Flavonoids Activation of the Transcription Factor Nrf2 as a Hypothesis Approach for the Prevention and Modulation of SARS-CoV-2 Infection Severity. Antioxidants (Basel). 2020 Jul 24; 9(8). PMID: 32722164.
      Citations:    
    48. Messeha SS, Zarmouh NO, Mendonca P, Cotton C, Soliman KFA. Molecular mechanism of gossypol mediating CCL2 and IL-8 attenuation in triple-negative breast cancer cells. Mol Med Rep. 2020 08; 22(2):1213-1226. PMID: 32627003.
      Citations: 3     Fields:    Translation:HumansCells
    49. Hilliard A, Mendonca P, Soliman KFA. Involvement of NF?B and MAPK signaling pathways in the preventive effects of Ganoderma lucidum on the inflammation of BV-2 microglial cells induced by LPS. J Neuroimmunol. 2020 08 15; 345:577269. PMID: 32480240.
      Citations: 13     Fields:    Translation:AnimalsCells
    50. Zarmouh NO, Messeha SS, Mateeva N, Gangapuram M, Flowers K, Eyunni SVK, Zhang W, Redda KK, Soliman KFA. The Antiproliferative Effects of Flavonoid MAO Inhibitors on Prostate Cancer Cells. Molecules. 2020 May 11; 25(9). PMID: 32403270.
      Citations: 4     Fields:    Translation:HumansCells
    51. Bauer D, Mazzio E, Hilliard A, Oriaku ET, Soliman KFA. Effect of apigenin on whole transcriptome profile of TNFa-activated MDA-MB-468 triple negative breast cancer cells. Oncol Lett. 2020 Mar; 19(3):2123-2132. PMID: 32194710.
      Citations:    
    52. Bauer D, Mazzio E, Soliman KFA. Whole Transcriptomic Analysis of Apigenin on TNFa Immuno-activated MDA-MB-231 Breast Cancer Cells. Cancer Genomics Proteomics. 2019 Nov-Dec; 16(6):421-431. PMID: 31659097.
      Citations: 15     Fields:    Translation:HumansCells
    53. Mendonca P, Horton A, Bauer D, Messeha S, Soliman KFA. The inhibitory effects of butein on cell proliferation and TNF-a-induced CCL2 release in racially different triple negative breast cancer cells. PLoS One. 2019; 14(10):e0215269. PMID: 31665136.
      Citations: 9     Fields:    Translation:HumansCells
    54. Jones PM, Mazzio E, Soliman K, George AM. In Silico Investigation of the Binding of MCoTI-II Plant Defense Knottin to the ?-NGF Serine Protease of the 7S Nerve Growth Factor Complex and Biological Activity of Its NGF Mimetic Properties. J Phys Chem B. 2019 10 31; 123(43):9104-9110. PMID: 31580077.
      Citations: 1     Fields:    Translation:AnimalsCells
    55. Mendonca P, Darwish AG, Tsolova V, El-Sharkawy I, Soliman KFA. The Anticancer and Antioxidant Effects of Muscadine Grape Extracts on Racially Different Triple-negative Breast Cancer Cells. Anticancer Res. 2019 Aug; 39(8):4043-4053. PMID: 31366486.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    56. Badisa RB, Wiley C, Randell K, Darling-Reed SF, Latinwo LM, Agharahimi M, Soliman KFA, Goodman CB. Identification of cytotoxic markers in methamphetamine treated rat C6 astroglia-like cells. Sci Rep. 2019 06 28; 9(1):9412. PMID: 31253835.
      Citations: 4     Fields:    Translation:AnimalsCells
    57. Mendonca P, Taka E, Soliman KFA. Proteomic analysis of the effect of the polyphenol pentagalloyl glucose on proteins involved in neurodegenerative diseases in activated BV-2 microglial cells. Mol Med Rep. 2019 Aug; 20(2):1736-1746. PMID: 31257500.
      Citations: 4     Fields:    Translation:AnimalsCells
    58. Messeha SS, Zarmouh NO, Mendonca P, Alwagdani H, Cotton C, Soliman KFA. Effects of gossypol on apoptosis-related gene expression in racially distinct triple-negative breast cancer cells. Oncol Rep. 2019 Aug; 42(2):467-478. PMID: 31173249.
      Citations: 12     Fields:    Translation:HumansCells
    59. Ofili EO, Tchounwou PB, Fernandez-Repollet E, Yanagihara R, Akintobi TH, Lee JE, Malouhi M, Garner ST, Hayes TT, Baker AR, Dent AL, Abdelrahim M, Rollins L, Chang SP, Sy A, Hernandez BY, Bullard PL, Noel RJ, Shiramizu B, Hedges JR, Berry MJ, Bond VC, Lima MF, Mokuau N, Kirken RA, Cruz-Correa M, Sarpong DF, Vadgama J, Yates C, Kahn SA, Soliman KF, Perry G, Pezzano M, Luciano CA, Barnett ME, Oyekan A, Kumar D, Norris KC. The Research Centers in Minority Institutions (RCMI) Translational Research Network: Building and Sustaining Capacity for Multi-Site Basic Biomedical, Clinical and Behavioral Research. Ethn Dis. 2019; 29(Suppl 1):135-144. PMID: 30906162.
      Citations: 18     Fields:    Translation:Humans
    60. Mendonca P, Taka E, Bauer D, Reams RR, Soliman KFA. The attenuating effects of 1,2,3,4,6 penta-O-galloyl-?-d-glucose on pro-inflammatory responses of LPS/IFN?-activated BV-2 microglial cells through NF?B and MAPK signaling pathways. J Neuroimmunol. 2018 11 15; 324:43-53. PMID: 30236786.
      Citations: 12     Fields:    Translation:AnimalsCells
    61. Mazzio EA, Soliman KFA. Whole-transcriptomic Profile of SK-MEL-3 Melanoma Cells Treated with the Histone Deacetylase Inhibitor: Trichostatin A. Cancer Genomics Proteomics. 2018 Sep-Oct; 15(5):349-364. PMID: 30194076.
      Citations: 14     Fields:    Translation:HumansCells
    62. Hedges JR, Soliman KFA, D'Amour G, Liang D, Rodr?guez-D?az CE, Thompson K, Romaguera J, Rabionet Sabater SE, Yanagihara R. Academic Response to Storm-Related Natural Disasters-Lessons Learned. Int J Environ Res Public Health. 2018 Aug 17; 15(8). PMID: 30126101.
      Citations: 2     Fields:    Translation:Humans
    63. Messeha SS, Zarmouh NO, Mendonca P, Alwagdani H, Kolta MG, Soliman KFA. The inhibitory effects of plumbagin on the NF-?B pathway and CCL2 release in racially different triple-negative breast cancer cells. PLoS One. 2018; 13(7):e0201116. PMID: 30059519.
      Citations: 12     Fields:    Translation:HumansCells
    64. Mazzio EA, Lewis CA, Elhag R, Soliman KF. Effects of Sepantronium Bromide (YM-155) on the Whole Transcriptome of MDA-MB-231 Cells: Highlight on Impaired ATR/ATM Fanconi Anemia DNA Damage Response. Cancer Genomics Proteomics. 2018 Jul-Aug; 15(4):249-264. PMID: 29976630.
      Citations: 5     Fields:    Translation:HumansCells
    65. Cobourne-Duval MK, Taka E, Mendonca P, Soliman KFA. Thymoquinone increases the expression of neuroprotective proteins while decreasing the expression of pro-inflammatory cytokines and the gene expression NF?B pathway signaling targets in LPS/IFN? -activated BV-2 microglia cells. J Neuroimmunol. 2018 07 15; 320:87-97. PMID: 29759145.
      Citations: 34     Fields:    Translation:AnimalsCells
    66. Mazzio EA, Lewis CA, Soliman KFA. Transcriptomic Profiling of MDA-MB-231 Cells Exposed to Boswellia Serrata and 3-O-Acetyl-B-Boswellic Acid; ER/UPR Mediated Programmed Cell Death. Cancer Genomics Proteomics. 2017 Nov-Dec; 14(6):409-425. PMID: 29109091.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    67. Messeha SS, Zarmouh NO, Mendonca P, Kolta MG, Soliman KFA. The attenuating effects of plumbagin on pro-inflammatory cytokine expression in LPS-activated BV-2 microglial cells. J Neuroimmunol. 2017 12 15; 313:129-137. PMID: 28950995.
      Citations: 10     Fields:    Translation:AnimalsCells
    68. Bauer D, Redmon N, Mazzio E, Soliman KF. Apigenin inhibits TNFa/IL-1a-induced CCL2 release through IKBK-epsilon signaling in MDA-MB-231 human breast cancer cells. PLoS One. 2017; 12(4):e0175558. PMID: 28441391.
      Citations: 34     Fields:    Translation:HumansAnimalsCells
    69. Mack N, Mazzio EA, Bauer D, Flores-Rozas H, Soliman KF. Stable shRNA Silencing of Lactate Dehydrogenase A (LDHA) in Human MDA-MB-231 Breast Cancer Cells Fails to Alter Lactic Acid Production, Glycolytic Activity, ATP or Survival. Anticancer Res. 2017 03; 37(3):1205-1212. PMID: 28314283.
      Citations: 22     Fields:    Translation:HumansCells
    70. Mendonca P, Taka E, Bauer D, Cobourne-Duval M, Soliman KF. The attenuating effects of 1,2,3,4,6 penta-O-galloyl-?-d-glucose on inflammatory cytokines release from activated BV-2 microglial cells. J Neuroimmunol. 2017 04 15; 305:9-15. PMID: 28284353.
      Citations: 13     Fields:    Translation:AnimalsCells
    71. Zarmouh NO, Eyunni SK, Soliman KF. The Benzopyrone Biochanin-A as a reversible, competitive, and selective monoamine oxidase B inhibitor. BMC Complement Altern Med. 2017 Jan 10; 17(1):34. PMID: 28069007.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    72. Mazzio EA, Soliman KF. HTP Nutraceutical Screening for Histone Deacetylase Inhibitors and Effects of HDACis on Tumor-suppressing miRNAs by Trichostatin A and Grapeseed (Vitis vinifera) in HeLa cells. Cancer Genomics Proteomics. 2017 01 02; 14(1):17-33. PMID: 28031235.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    73. Mazzio EA, Bauer D, Mendonca P, Taka E, Soliman KF. Natural product HTP screening for attenuation of cytokine-induced neutrophil chemo attractants (CINCs) and NO2- in LPS/IFN? activated glioma cells. J Neuroimmunol. 2017 01 15; 302:10-19. PMID: 27956075.
      Citations: 9     Fields:    Translation:AnimalsCells
    74. Mazzio EA, Li N, Bauer D, Mendonca P, Taka E, Darb M, Thomas L, Williams H, Soliman KF. Natural product HTP screening for antibacterial (E.coli 0157:H7) and anti-inflammatory agents in (LPS from E. coli O111:B4) activated macrophages and microglial cells; focus on sepsis. BMC Complement Altern Med. 2016 Nov 15; 16(1):467. PMID: 27846826.
      Citations: 18     Fields:    Translation:HumansAnimalsCells
    75. Gangapuram M, Jean R, Mazzio E, Badisa R, Eyunni S, Goodman CB, Redda KK, Soliman KF. Substituted Tetrahydroisoquinolines as Microtubule-destabilizing Agents in Triple Negative Human Breast Cancer Cells. Anticancer Res. 2016 10; 36(10):5043-5052. PMID: 27798863.
      Citations: 3     Fields:    Translation:HumansCells
    76. Cobourne-Duval MK, Taka E, Mendonca P, Bauer D, Soliman KF. The Antioxidant Effects of Thymoquinone in Activated BV-2 Murine Microglial Cells. Neurochem Res. 2016 Dec; 41(12):3227-3238. PMID: 27585756.
      Citations: 23     Fields:    Translation:AnimalsCells
    77. Ramsubhag RR, Massaro CL, Dadich CM, Janeczek AJ, Hoang TT, Mazzio EA, Eyunni S, Soliman KF, Dudley GB. Synthesis of "neoprofen", a rigidified analogue of ibuprofen, exemplifying synthetic methodology for altering the 3-D topology of pharmaceutical substances. Org Biomol Chem. 2016 Aug 16; 14(33):7855-8. PMID: 27492587.
      Citations: 1     Fields:    Translation:HumansCells
    78. Zarmouh NO, Messeha SS, Elshami FM, Soliman KF. Natural Products Screening for the Identification of Selective Monoamine Oxidase-B Inhibitors. European J Med Plants. 2016 May; 15(1). PMID: 27341283.
      Citations:    
    79. Mochona B, Qi X, Euynni S, Sikazwi D, Mateeva N, Soliman KF. Design and evaluation of novel oxadiazole derivatives as potential prostate cancer agents. Bioorg Med Chem Lett. 2016 06 15; 26(12):2847-2851. PMID: 27156770.
      Citations: 2     Fields:    Translation:HumansCells
    80. Zarmouh NO, Messeha SS, Elshami FM, Soliman KF. Evaluation of the Isoflavone Genistein as Reversible Human Monoamine Oxidase-A and -B Inhibitor. Evid Based Complement Alternat Med. 2016; 2016:1423052. PMID: 27118978.
      Citations:    
    81. Zarmouh NO, Mazzio EA, Elshami FM, Messeha SS, Eyunni SV, Soliman KF. Evaluation of the Inhibitory Effects of Bavachinin and Bavachin on Human Monoamine Oxidases A and B. Evid Based Complement Alternat Med. 2015; 2015:852194. PMID: 26557867.
      Citations:    
    82. Taka E, Mazzio EA, Goodman CB, Redmon N, Flores-Rozas H, Reams R, Darling-Reed S, Soliman KF. Anti-inflammatory effects of thymoquinone in activated BV-2 microglial cells. J Neuroimmunol. 2015 Sep 15; 286:5-12. PMID: 26298318.
      Citations: 23     Fields:    Translation:AnimalsCells
    83. Mazzio E, Georges B, McTier O, Soliman KF. Neurotrophic Effects of Mu Bie Zi (Momordica cochinchinensis) Seed Elucidated by High-Throughput Screening of Natural Products for NGF Mimetic Effects in PC-12 Cells. Neurochem Res. 2015 Oct; 40(10):2102-12. PMID: 25862192.
      Citations: 2     Fields:    Translation:AnimalsCells
    84. Mateeva N, Gangapuram M, Mazzio E, Eyunni S, Soliman KF, Redda KK. Biological evaluation of synthetic chalcone and flavone derivatives as anti-inflammatory agents. Med Chem Res. 2015 Apr; 24(4):1672-1680. PMID: 25866456.
      Citations:    
    85. Deiab S, Mazzio E, Eyunni S, McTier O, Mateeva N, Elshami F, Soliman KF. 1,2,3,4,6-Penta-O-galloylglucose within Galla Chinensis Inhibits Human LDH-A and Attenuates Cell Proliferation in MDA-MB-231 Breast Cancer Cells. Evid Based Complement Alternat Med. 2015; 2015:276946. PMID: 25918543.
      Citations:    
    86. Elhag R, Mazzio EA, Soliman KF. The effect of silibinin in enhancing toxicity of temozolomide and etoposide in p53 and PTEN-mutated resistant glioma cell lines. Anticancer Res. 2015 Mar; 35(3):1263-9. PMID: 25750273.
      Citations: 14     Fields:    Translation:HumansCells
    87. Reams RR, Jones-Triche J, Chan OT, Hernandez BY, Soliman KF, Yates C. Immunohistological analysis of ABCD3 expression in Caucasian and African American prostate tumors. Biomed Res Int. 2015; 2015:132981. PMID: 25802834.
      Citations: 7     Fields:    Translation:Humans
    88. Badisa RB, Mina DA, Latinwo LM, Soliman KF. Selective anticancer activity of neurotoxin 1-methyl-4-phenylpyridinium on non-small cell lung adenocarcinoma A549 cells. Anticancer Res. 2014 Oct; 34(10):5447-52. PMID: 25275040.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    89. Green JE, Cooperwood JS, Taka E, Soliman KF, Goodman CB, Reams RR. Comparative proteomic analysis reveals growth inhibition by 3-N-alkyloxyestradiol derivative (SERM) in prostate cancer cells. Cancer Genomics Proteomics. 2014 Jul-Aug; 11(4):195-200. PMID: 25048348.
      Citations:    Fields:    Translation:HumansCells
    90. Bauer D, Mazzio E, Soliman KF, Taka E, Oriaku E, Womble T, Darling-Reed S. Diallyl disulfide inhibits TNFa-induced CCL2 release by MDA-MB-231 cells. Anticancer Res. 2014 Jun; 34(6):2763-70. PMID: 24922637.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    91. Mazzio EA, Soliman KF. Epigenetics and nutritional environmental signals. Integr Comp Biol. 2014 Jul; 54(1):21-30. PMID: 24861811.
      Citations: 17     Fields:    Translation:HumansCells
    92. Gangapuram M, Mazzio E, Eyunni S, Soliman KF, Redda KK. Synthesis and biological evaluation of substituted N-[3-(1H-pyrrol-1-yl)methyl]-1,2,5,6-tetrahydropyridin-1-yl]benzamide/benzene sulfonamides as anti-inflammatory agents. Arch Pharm (Weinheim). 2014 May; 347(5):360-9. PMID: 24585402.
      Citations: 2     Fields:    Translation:AnimalsCells
    93. Stephenson AP, Schneider JA, Nelson BC, Atha DH, Jain A, Soliman KF, Aschner M, Mazzio E, Renee Reams R. Manganese-induced oxidative DNA damage in neuronal SH-SY5Y cells: attenuation of thymine base lesions by glutathione and N-acetylcysteine. Toxicol Lett. 2013 Apr 26; 218(3):299-307. PMID: 23296100.
      Citations: 37     Fields:    Translation:HumansCells
    94. Hardaway CM, Badisa RB, Soliman KF. Effect of ascorbic acid and hydrogen peroxide on mouse neuroblastoma cells. Mol Med Rep. 2012 06; 5(6):1449-52. PMID: 22469841.
      Citations: 11     Fields:    Translation:AnimalsCells
    95. Mazzio EA, Boukli N, Rivera N, Soliman KF. Pericellular pH homeostasis is a primary function of the Warburg effect: inversion of metabolic systems to control lactate steady state in tumor cells. Cancer Sci. 2012 Mar; 103(3):422-32. PMID: 22320183.
      Citations: 31     Fields:    Translation:AnimalsCells
    96. Mazzio EA, Soliman KF. Basic concepts of epigenetics: impact of environmental signals on gene expression. Epigenetics. 2012 Feb; 7(2):119-30. PMID: 22395460.
      Citations: 85     Fields:    Translation:HumansAnimalsCells
    97. Taka E, Mazzio E, Soliman KF, Renee Reams R. Microarray genomic profile of mitochondrial and oxidant response in manganese chloride treated PC12 cells. Neurotoxicology. 2012 Mar; 33(2):162-8. PMID: 22281203.
      Citations: 5     Fields:    Translation:AnimalsCells
    98. Reams RR, Kalari KR, Wang H, Odedina FT, Soliman KF, Yates C. Detecting gene-gene interactions in prostate disease in African American men. Infect Agent Cancer. 2011 Sep 23; 6 Suppl 2:S1. PMID: 21992608.
      Citations:    
    99. Mazzio EA, Close F, Soliman KF. The biochemical and cellular basis for nutraceutical strategies to attenuate neurodegeneration in Parkinson's disease. Int J Mol Sci. 2011 Jan 17; 12(1):506-69. PMID: 21340000.
      Citations: 9     Fields:    Translation:Humans
    100. Mazzio EA, Soliman KF. In vitro screening of tumoricidal properties of international medicinal herbs: part II. Phytother Res. 2010 Dec; 24(12):1813-24. PMID: 20564497.
      Citations: 5     Fields:    Translation:AnimalsCells
    101. Badisa RB, Darling-Reed SF, Soliman KF. The protective role of D-glucose against 1-methyl-4-phenylpyridinium ion (MPP+): induced mitochondrial dysfunction in C6 astroglial cells. Neurochem Res. 2010 Sep; 35(9):1413-21. PMID: 20508987.
      Citations: 9     Fields:    Translation:AnimalsCells
    102. Mazzio EA, Soliman YI, Soliman KF. Variable toxicological response to the loss of OXPHOS through 1-methyl-4-phenylpyridinium-induced mitochondrial damage and anoxia in diverse neural immortal cell lines. Cell Biol Toxicol. 2010 Dec; 26(6):527-39. PMID: 20401737.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    103. Mazzio EA, Smith B, Soliman KF. Evaluation of endogenous acidic metabolic products associated with carbohydrate metabolism in tumor cells. Cell Biol Toxicol. 2010 Jun; 26(3):177-88. PMID: 19784859.
      Citations: 20     Fields:    Translation:HumansCells
    104. Becker A, Soliman KF. The role of intracellular glutathione in inorganic mercury-induced toxicity in neuroblastoma cells. Neurochem Res. 2009 Sep; 34(9):1677-84. PMID: 19347580.
      Citations: 9     Fields:    Translation:AnimalsCells
    105. Mazzio EA, Soliman KF. In vitro screening for the tumoricidal properties of international medicinal herbs. Phytother Res. 2009 Mar; 23(3):385-98. PMID: 18844256.
      Citations: 27     Fields:    Translation:HumansAnimalsCells
    106. Reams RR, Agrawal D, Davis MB, Yoder S, Odedina FT, Kumar N, Higginbotham JM, Akinremi T, Suther S, Soliman KF. Microarray comparison of prostate tumor gene expression in African-American and Caucasian American males: a pilot project study. Infect Agent Cancer. 2009 Feb 10; 4 Suppl 1:S3. PMID: 19208208.
      Citations:    
    107. Williams ZR, Goodman CB, Soliman KF. Anaerobic glycolysis protection against 1-methy-4-phenylpyridinium (MPP+) toxicity in C6 glioma cells. Neurochem Res. 2007 Jun; 32(6):1071-80. PMID: 17401669.
      Citations: 10     Fields:    Translation:AnimalsCells
    108. Lee E, Williams Z, Goodman CB, Oriaku ET, Harris C, Thomas M, Soliman KF. Effects of NMDA receptor inhibition by phencyclidine on the neuronal differentiation of PC12 cells. Neurotoxicology. 2006 Jul; 27(4):558-66. PMID: 16580729.
      Citations: 2     Fields:    Translation:AnimalsCells
    109. Shepherd KR, Lee ES, Schmued L, Jiao Y, Ali SF, Oriaku ET, Lamango NS, Soliman KF, Charlton CG. The potentiating effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) on paraquat-induced neurochemical and behavioral changes in mice. Pharmacol Biochem Behav. 2006 Mar; 83(3):349-59. PMID: 16580056.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    110. Lee ES, Chen H, Charlton CG, Soliman KF. The role of phospholipid methylation in 1-methyl-4-phenyl-pyridinium ion (MPP+)-induced neurotoxicity in PC12 cells. Neurotoxicology. 2005 Dec; 26(6):945-57. PMID: 15950286.
      Citations: 5     Fields:    Translation:AnimalsCells
    111. Lee ES, Chen H, Soliman KF, Charlton CG. Effects of homocysteine on the dopaminergic system and behavior in rodents. Neurotoxicology. 2005 Jun; 26(3):361-71. PMID: 15935208.
      Citations: 30     Fields:    Translation:AnimalsCells
    112. Mazzio EA, Kolta MG, Reams RR, Soliman KF. Inhibitory effects of cigarette smoke on glial inducible nitric oxide synthase and lack of protective properties against oxidative neurotoxins in vitro. Neurotoxicology. 2005 Jan; 26(1):49-62. PMID: 15527873.
      Citations: 8     Fields:    Translation:AnimalsCells
    113. Lee ES, Soliman KF, Charlton CG. Lysophosphatidylcholine decreases locomotor activities and dopamine turnover rate in rats. Neurotoxicology. 2005 Jan; 26(1):27-38. PMID: 15527871.
      Citations: 7     Fields:    Translation:Animals
    114. Elsisi NS, Darling-Reed S, Lee EY, Oriaku ET, Soliman KF. Ibuprofen and apigenin induce apoptosis and cell cycle arrest in activated microglia. Neurosci Lett. 2005 Feb 28; 375(2):91-6. PMID: 15670648.
      Citations: 24     Fields:    Translation:AnimalsCells
    115. Lee ES, Chen H, Shepherd KR, Lamango NS, Soliman KF, Charlton CG. Inhibitory effects of lysophosphatidylcholine on the dopaminergic system. Neurochem Res. 2004 Jul; 29(7):1333-42. PMID: 15202762.
      Citations: 4     Fields:    Translation:AnimalsCells
    116. Mazzio EA, Reams RR, Soliman KF. The role of oxidative stress, impaired glycolysis and mitochondrial respiratory redox failure in the cytotoxic effects of 6-hydroxydopamine in vitro. Brain Res. 2004 Apr 09; 1004(1-2):29-44. PMID: 15033417.
      Citations: 35     Fields:    Translation:AnimalsCells
    117. Mazzio EA, Soliman KF. Effects of enhancing mitochondrial oxidative phosphorylation with reducing equivalents and ubiquinone on 1-methyl-4-phenylpyridinium toxicity and complex I-IV damage in neuroblastoma cells. Biochem Pharmacol. 2004 Mar 15; 67(6):1167-84. PMID: 15006552.
      Citations: 7     Fields:    Translation:AnimalsCells
    118. Mazzio EA, Soliman KF. Glioma cell antioxidant capacity relative to reactive oxygen species produced by dopamine. J Appl Toxicol. 2004 Mar-Apr; 24(2):99-106. PMID: 15052604.
      Citations: 13     Fields:    Translation:AnimalsCells
    119. Lee ES, Chen H, Shepherd KR, Lamango NS, Soliman KF, Charlton CG. The inhibitory role of methylation on the binding characteristics of dopamine receptors and transporter. Neurosci Res. 2004 Mar; 48(3):335-44. PMID: 15154679.
      Citations: 7     Fields:    Translation:AnimalsCells
    120. Mazzio E, Yoon KJ, Soliman KF. Acetyl-L-carnitine cytoprotection against 1-methyl-4-phenylpyridinium toxicity in neuroblastoma cells. Biochem Pharmacol. 2003 Jul 15; 66(2):297-306. PMID: 12826272.
      Citations: 8     Fields:    Translation:AnimalsCells
    121. Mazzio E, Becker A, Soliman KF. Inflammation and inducible nitric oxide synthase have no effect on monoamine oxidase activity in glioma cells. Biochem Pharmacol. 2003 May 15; 65(10):1719-27. PMID: 12754108.
      Citations: 2     Fields:    Translation:AnimalsCells
    122. Mazzio EA, Soliman KF. Cytoprotection of pyruvic acid and reduced beta-nicotinamide adenine dinucleotide against hydrogen peroxide toxicity in neuroblastoma cells. Neurochem Res. 2003 May; 28(5):733-41. PMID: 12716024.
      Citations: 19     Fields:    Translation:AnimalsCells
    123. Sircar R, Soliman KF. Effects of postnatal PCP treatment on locomotor behavior and striatal D2 receptor. Pharmacol Biochem Behav. 2003 Mar; 74(4):943-52. PMID: 12667909.
      Citations: 7     Fields:    Translation:AnimalsCells
    124. Mazzio E, Soliman KF. Pyruvic acid cytoprotection against 1-methyl-4-phenylpyridinium, 6-hydroxydopamine and hydrogen peroxide toxicities in vitro. Neurosci Lett. 2003 Feb 06; 337(2):77-80. PMID: 12527392.
      Citations: 21     Fields:    Translation:AnimalsCells
    125. Mazzio E, Soliman KF. The role of glycolysis and gluconeogenesis in the cytoprotection of neuroblastoma cells against 1-methyl 4-phenylpyridinium ion toxicity. Neurotoxicology. 2003 Jan; 24(1):137-47. PMID: 12564389.
      Citations: 19     Fields:    Translation:AnimalsCells
    126. Zhao WQ, Williams Z, Shepherd KR, Reuben JS, Lee ES, Darling-Reed S, Lamango N, Soliman KF, Charlton CG. S-adenosyl-methionine-induced apoptosis in PC12 cells. J Neurosci Res. 2002 Aug 15; 69(4):519-29. PMID: 12210845.
      Citations: 7     Fields:    Translation:AnimalsCells
    127. Choi SJ, Mazzio E, Kolta MG, Soliman KFA. Prenatal Cocaine Exposure Affects Postnatal Dopaminergic Systems in Various Regions of the Rat Braina. Ann N Y Acad Sci. 1998 May; 844(1):293-302. PMID: 29090805.
      Citations: 1     Fields:    
    128. Clay LH, Mazzio EA, Kolta MG, Soliman KFA. Repeated Administration of Cocaine Alters Dopamine Uptake and Release in the Striatum Nucleus Accumbensa. Ann N Y Acad Sci. 1998 May; 844(1):346-355. PMID: 29090828.
      Citations:    Fields:    
    129. Choi SJ, Mazzio E, Soliman KFA. The Effects of Gestational Cocaine Exposure on Pregnancy Outcome, Postnatal Development, Cognition and Locomotion in Ratsa. Ann N Y Acad Sci. 1998 May; 844(1):324-335. PMID: 29090825.
      Citations:    Fields:    
    130. Choi SJ, Mazzio EA, Reams RR, Soliman KFA. Gestational Cocaine Exposure Alters Postnatal Pituitary-Adrenal Axis Activity and Stress Endurance in Ratsa. Ann N Y Acad Sci. 1998 May; 844(1):336-345. PMID: 29090826.
      Citations:    Fields:    
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