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Thomas Huckaba

TitleFaculty, Department of Biology
Faculty RankAssociate Professor
InstitutionXavier University of Louisiana
DepartmentBiology
Phone5045205012
ORCID ORCID Icon0000-0002-6711-9175 Additional info
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    Collapse Biography 
    Collapse education and training
    University of Oregon, Eugene, ORBS06/1994Biology, Chemistry, Political Science
    East Tennessee State University - Quillen College of Medicine, Johnson City, TNMS08/2000Physiology
    Columbia University - College of Physicians and Surgeons, New York, NYPhD05/2006Cell Biology
    University of California, San Francisco, San Francisco, CA(postdoc)06/2011Cell Biology

    Collapse Overview 
    Collapse overview
    My laboratory is focused on the role of motor proteins and the cytoskeleton in neurodegenerative disease. We use a combination of cell biological, biochemical, and biophysical tools to better understand the mechanism of disease onset and to test potential therapeutics.

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Goyal N, Do C, Hill-Odom M, Beamon T, Ponnapakkam T, Liu J, Sridhar J, Huckaba T, Foroozesh M. Study of Ceramide-Flavone Analogs Showing Self-Fluorescence and Anti-Proliferation Activities. J Oncol Res Ther. 2023; 8(2). PMID: 37538786.
      Citations:    
    2. Sing CN, Garcia EJ, Lipkin TG, Huckaba TM, Tsang CA, Coughlin AC, Yang EJ, Boldogh IR, Higuchi-Sanabria R, Pon LA. Identification of a modulator of the actin cytoskeleton, mitochondria, nutrient metabolism and lifespan in yeast. Nat Commun. 2022 05 16; 13(1):2706. PMID: 35577788.
      Citations: 6     Fields:    Translation:AnimalsCells
    3. Crawford L, Bart H, Harold EL, Huckaba TM, Davenport IR. Tube-like structures within the ovarian follicle of Hydrolagus colliei indicate the early origins of follicle cell processes. J Fish Biol. 2020 Sep; 97(3):691-695. PMID: 32506516.
      Citations:    Fields:    Translation:Animals
    4. Maziveyi M, Dong S, Baranwal S, Mehrnezhad A, Rathinam R, Huckaba TM, Mercante DE, Park K, Alahari SK. Exosomes from Nischarin-Expressing Cells Reduce Breast Cancer Cell Motility and Tumor Growth. Cancer Res. 2019 May 01; 79(9):2152-2166. PMID: 30635277.
      Citations: 16     Fields:    Translation:AnimalsCells
    5. Jennings S, Chenevert M, Liu L, Mottamal M, Wojcik EJ, Huckaba TM. Characterization of kinesin switch I mutations that cause hereditary spastic paraplegia. PLoS One. 2017; 12(7):e0180353. PMID: 28678816.
      Citations: 15     Fields:    Translation:HumansCells
    6. Dunbar M, Onuora C, Morgan S, Stone FE, Huckaba TM, Davenport IR. Follicle cell processes: a shark thing? J Fish Biol. 2017 Mar; 90(3):1031-1036. PMID: 27781275.
      Citations:    Fields:    Translation:AnimalsCells
    7. Hossain A, Tauhid L, Davenport I, Huckaba T, Graves R, Mandal T, Muniruzzaman S, Ahmed SA, Bhattacharjee PS. LRP-1 Pathway Targeted Inhibition of Vascular Abnormalities in the Retina of Diabetic Mice. Curr Eye Res. 2017 04; 42(4):640-647. PMID: 27442082.
      Citations: 6     Fields:    Translation:AnimalsCells
    8. Hossain A, Heron D, Davenport I, Huckaba T, Graves R, Mandal T, Muniruzzaman S, Wang S, Bhattacharjee PS. Protective effects of bestatin in the retina of streptozotocin-induced diabetic mice. Exp Eye Res. 2016 08; 149:100-106. PMID: 27344955.
      Citations: 9     Fields:    Translation:Animals
    9. Wojcik EJ, Buckley RS, Richard J, Liu L, Huckaba TM, Kim S. Kinesin-5: cross-bridging mechanism to targeted clinical therapy. Gene. 2013 Dec 01; 531(2):133-49. PMID: 23954229.
      Citations: 34     Fields:    Translation:HumansAnimalsCells
    10. Huckaba TM, Gennerich A, Wilhelm JE, Chishti AH, Vale RD. Kinesin-73 is a processive motor that localizes to Rab5-containing organelles. J Biol Chem. 2011 Mar 04; 286(9):7457-67. PMID: 21169635.
      Citations: 31     Fields:    Translation:AnimalsCells
    11. Huckaba TM, Lipkin T, Pon LA. Roles of type II myosin and a tropomyosin isoform in retrograde actin flow in budding yeast. J Cell Biol. 2006 Dec 18; 175(6):957-69. PMID: 17178912.
      Citations: 51     Fields:    Translation:AnimalsCells
    12. Eng CH, Huckaba TM, Gundersen GG. The formin mDia regulates GSK3beta through novel PKCs to promote microtubule stabilization but not MTOC reorientation in migrating fibroblasts. Mol Biol Cell. 2006 Dec; 17(12):5004-16. PMID: 16987962.
      Citations: 55     Fields:    Translation:AnimalsCells
    13. Fehrenbacher KL, Yang HC, Gay AC, Huckaba TM, Pon LA. Live cell imaging of mitochondrial movement along actin cables in budding yeast. Curr Biol. 2004 Nov 23; 14(22):1996-2004. PMID: 15556861.
      Citations: 77     Fields:    Translation:AnimalsCells
    14. Huckaba TM, Gay AC, Pantalena LF, Yang HC, Pon LA. Live cell imaging of the assembly, disassembly, and actin cable-dependent movement of endosomes and actin patches in the budding yeast, Saccharomyces cerevisiae. J Cell Biol. 2004 Nov 08; 167(3):519-30. PMID: 15534003.
      Citations: 90     Fields:    Translation:AnimalsCells
    15. Fehrenbacher K, Huckaba T, Yang HC, Boldogh I, Pon L. Actin comet tails, endosomes and endosymbionts. J Exp Biol. 2003 Jun; 206(Pt 12):1977-84. PMID: 12756279.
      Citations: 21     Fields:    Translation:Cells
    16. Huckaba TM, Pon LA. Cytokinesis: rho and formins are the ringleaders. Curr Biol. 2002 Dec 10; 12(23):R813-4. PMID: 12477408.
      Citations: 1     Fields:    Translation:Animals
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