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Maria del Pilar Aguinaga

TitleAssociate Director adn Laboratory Director, Meharry Sickle Cell Center
Faculty RankProfessor
InstitutionMeharry Medical College
DepartmentObstetrics adn Gynecology
Address1005 Dr. D.B. Todd, Jr. Boulevard
Nashville TN 37208-3599
Phone6153276591
Fax6153276733
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    Collapse Biography 
    Collapse awards and honors
    1995 - 2001National Committee for Clinical Laboraory Standards, Subcommittee on Hemoglobinopathies, NCCLS
    2000Mentor of the Year, Meharry Medical College
    2001Distinguished Service Award, Meharry Medical College
    2003 - 2008Board Member and Chair of the Sub-committee on Evaluation and Content, YMCA of Middle Tennessee
    2004Minority Education Institution of the Year Award, Oak Ridge National Laboratory and Department of Energy
    2005Latino Achievers Dedicated Support Award, YMCA of Middle Tennessee
    2007 - 2016Awards Committee, American Society of Hematology
    2007 - 2009Chair of the Board. Latina Achievers Program, YMCA of Middle Tennessee
    2010 - 2016Appointed Member - Genetics Advisory Committee, Sate of Tennessee Department of Health
    2011 - 2013President, Just Hematology Society
    2012Appointed Reviewer-Consensus Committee on Hematology, Clinical Laboratory Standards Institute
    2013Appointed Advisor-Consensus Committee on Hematology, Clinical Laboratory Standards Institute
    2014 - 2015Hemoglobinopathy Working Group, Association of Public Health Laboratories and Centers for Disease Control and Prevention
    2014Grant Reviewer, NIH-R25 Special Emphasis Panel
    1990Permanent Visiting Professor, Universidad Peruana Cayetano Heredia, Lima Peru
    1979 - 1984Ministry of Education Science and Culture Japan Award, CRI Kanazawa University Medical School

    Collapse Overview 
    Collapse overview
    I have been working in sickle cell disease for many years as a researcher, mentor, instructor and clinical laboratory scientist, directing the State of Tennessee Hemoglobinopathy Confirmatory and Reference Laboratory for the Newborn Screening Program. I am also a tenured professor in the Department of Obstetrics
    and Gynecology, and have trained in my research laboratory, seventy individuals at different educational levels, from HS students to undergraduate, medical, graduate, postdoctoral and medical residents in sickle cell research. I have worked in prenatal diagnosis of Hemoglobinopathies, development of transgenic animal
    models for sickle cell disease, and the effect of hydroxyurea therapy in reproduction in sickle cell disease. I have a vast, diverse and unique experience in sickle cell disease that covers a wide array of knowledge, from basic, clinical and translational science to diagnostic services, cultural competency and health disparities.

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Dyal J, Kofman A, Kollie JZ, Fankhauser J, Orone R, Soka MJ, Glaybo U, Kiawu A, Freeman E, Giah G, Tony HD, Faikai M, Jawara M, Kamara K, Kamara S, Flowers B, Kromah ML, Desamu-Thorpe R, Graziano J, Brown S, Morales-Betoulle ME, Cannon DL, Su K, Linderman SL, Plucinski M, Rogier E, Bradbury RS, Secor WE, Bowden KE, Phillips C, Carrington MN, Park YH, Martin MP, Aguinaga MDP, Mushi R, Haberling DL, Ervin ED, Klena JD, Massaquoi M, Nyenswah T, Nichol ST, Chiriboga DE, Williams DE, Hinrichs SH, Ahmed R, Vonhm BT, Rollin PE, Purpura LJ, Choi MJ. Risk Factors for Ebola Virus Persistence in Semen of Survivors in Liberia. Clin Infect Dis. 2023 02 08; 76(3):e849-e856. PMID: 35639875.
      Citations: 1     Fields:    Translation:HumansCells
    2. Bender MA, Hulihan M, Dorley MC, Aguinaga MDP, Ojodu J, Yusuf C. Newborn Screening Practices for Beta-Thalassemia in the United States. Int J Neonatal Screen. 2021 Dec 13; 7(4). PMID: 34940053.
      Citations:    
    3. Kelley M, Cooper J, Devito D, Mushi R, Aguinaga MDP, Erenso DB. Laser trap ionization for identification of human erythrocytes with variable hemoglobin quantitation. J Biomed Opt. 2018 05; 23(5):1-10. PMID: 29851330.
      Citations: 5     Fields:    Translation:HumansCells
    4. Hong T, Hills E, Aguinaga MDP. Radiographically occult pulmonary metastases from gestational trophoblastic neoplasia. Radiol Case Rep. 2017 Jun; 12(2):292-294. PMID: 28491173.
      Citations:    
    5. Elkins T, Aguinaga Mdel P, Clinton-Selin C, Clinton B, Gotterer G. The Maternal Infant Health Outreach Worker program in low-income families. J Health Care Poor Underserved. 2013 Aug; 24(3):995-1001. PMID: 23974374.
      Citations: 3     Fields:    Translation:Humans
    6. Pellizzaro A, Welker G, Scott D, Solomon R, Cooper J, Farone A, Farone M, Mushi RS, Aguinaga Mdel P, Erenso D. Direct laser trapping for measuring the behavior of transfused erythrocytes in a sickle cell anemia patient. Biomed Opt Express. 2012 Sep 01; 3(9):2190-9. PMID: 23024913.
      Citations:    
    7. Farrell K, Dent L, Nguyen ML, Buchowski M, Bhatt A, Aguinaga Mdel P. The relationship of oxygen transport and cardiac index for the prevention of sickle cell crises. J Natl Med Assoc. 2010 Nov; 102(11):1000-7. PMID: 21141287.
      Citations: 3     Fields:    Translation:Humans
    8. Jones KM, Niaz MS, Brooks CM, Roberson SI, Aguinaga MP, Hills ER, Rice VM, Bourne P, Bruce D, Archibong AE. Adverse effects of a clinically relevant dose of hydroxyurea used for the treatment of sickle cell disease on male fertility endpoints. Int J Environ Res Public Health. 2009 03; 6(3):1124-44. PMID: 19440437.
      Citations: 16     Fields:    Translation:Animals
    9. Aguinaga MP, Wright CJ, Roa PD, Terrell F, Turner EA, Houston M. Molecular diagnosis and characterization of Hb Z?rich [beta63(E7)His-->Arg]] carriers in a Kentucky family. Hemoglobin. 1998 Sep-Nov; 22(5-6):509-15. PMID: 9859934.
      Citations:    Fields:    Translation:HumansCells
    10. Popp RA, Popp DM, Shinpock SG, Yang MY, Mural JG, Aguinaga MP, Kopsombut P, Roa PD, Turner EA, Rubin EM. A transgenic mouse model of hemoglobin S Antilles disease. Blood. 1997 Jun 01; 89(11):4204-12. PMID: 9166865.
      Citations: 6     Fields:    Translation:HumansAnimals
    11. Talley CJ, Turner EA, Hatcher FM, Aguinaga PM, Chakrabarti P. Tiazofurin-induced autosecretion of IL-6 and hemoglobin production in K562 human leukemia cells. Am J Hematol. 1997 Apr; 54(4):301-5. PMID: 9092685.
      Citations:    Fields:    Translation:HumansCells
    12. Roa D, Kopsombut P, Aguinaga MP, Turner EA. Hydroxyurea-induced denaturation of normal and sickle cell hemoglobins in vitro. J Clin Lab Anal. 1997; 11(4):208-13. PMID: 9219062.
      Citations: 3     Fields:    Translation:HumansCells
    13. Roa D, Turner EA, Aguinaga MD. Reference ranges for hemoglobin variants by HPLC in African Americans. Ann Clin Lab Sci. 1995 May-Jun; 25(3):228-35. PMID: 7605104.
      Citations: 2     Fields:    Translation:Humans
    14. Robbins V, Aguinaga MP, Valenzuela MS. Efficient isolation of whole genomic DNA from cell cultures and blood samples. Biotechniques. 1995 Mar; 18(3):414-6, 418. PMID: 7779389.
      Citations: 1     Fields:    Translation:HumansCells
    15. Aguinaga M, Sharan C, Singh DN, Kegler D, Siddiqui KA, Valenzuela MS. Chromosomal mapping and nucleotide sequence of a human DNA autonomously replicating sequence. Genomics. 1989 Oct; 5(3):605-11. PMID: 2613242.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    16. Aguinaga MP, Kiper CE, Valenzuela MS. Enriched autonomously replicating sequences in a nuclear matrix-DNA complex isolated from synchronized HeLa cells. Biochem Biophys Res Commun. 1987 Apr 29; 144(2):1018-24. PMID: 3034253.
      Citations: 6     Fields:    Translation:HumansCells
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