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Edmundo Kraiselburd
Title Director, Unit of Comparative Medicine
Faculty Rank Professor
Degree Ph.D.
Institution University of Puerto Rico
Department Microbiology and Zoology
Clusters HIV/AIDS
UPR-Medical Sciences Campus
School of Medicine
P.O. Box 365067
City San Juan
State PR
Postal Code 00936-5067
Telephone (787) 764-4325
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  Area of Expertise: SIV Vaccines / Animal Diseases / HIV / Neural Infections.

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1. Rivera LE, Kraiselburd E, Meléndez LM. Cystatin B and HIV regulate the STAT-1 signaling circuit in HIV-infected and INF-ß-treated human macrophages. J Neurovirol. 2016 10; 22(5):666-673.
2. Demers A, Kang G, Ma F, Lu W, Yuan Z, Li Y, Lewis M, Kraiselburd EN, Montaner L, Li Q. The mucosal expression pattern of interferon-e in rhesus macaques. J Leukoc Biol. 2014 Dec; 96(6):1101-7.
3. Rodriguez-Mercado R, Ford GD, Xu Z, Kraiselburd EN, Martinez MI, Eterovic VA, Colon E, Rodriguez IV, Portilla P, Ferchmin PA, Gierbolini L, Rodriguez-Carrasquillo M, Powell MD, Pulliam JV, McCraw CO, Gates A, Ford BD. Acute neuronal injury and blood genomic profiles in a nonhuman primate model for ischemic stroke. Comp Med. 2012 Oct; 62(5):427-38.
4. Castro Mdel R, Suarez E, Kraiselburd E, Isidro A, Paz J, Ferder L, Ayala-Torres S. Aging increases mitochondrial DNA damage and oxidative stress in liver of rhesus monkeys. Exp Gerontol. 2012 Jan; 47(1):29-37.
5. Sariol CA, Martínez MI, Rivera F, Rodríguez IV, Pantoja P, Abel K, Arana T, Giavedoni L, Hodara V, White LJ, Angleró YI, Montaner LJ, Kraiselburd EN. Decreased dengue replication and an increased anti-viral humoral response with the use of combined Toll-like receptor 3 and 7/8 agonists in macaques. PLoS One. 2011 Apr 29; 6(4):e19323.
6. Rivera-Amill V, Kumar R, Noel RJ, Garcia Y, Rodriguez IV, Martinez M, Sariol CA, Kraiselburd E, Iszard M, Mukherji M, Kumar S, Giavedoni LD, Kumar A. Short communication: Lack of immune response in rapid progressor morphine-dependent and SIV/SHIV-infected rhesus macaques is correlated with downregulation of TH1 cytokines. AIDS Res Hum Retroviruses. 2010 Aug; 26(8):919-22.
7. Veazey RS, O''Connor D, Kraiselburd E. Special issue: 26th Annual Symposium of Nonhuman Primate Models for AIDS. Introduction. J Med Primatol. 2009 Oct; 38 Suppl 1:1.
8. Sariol CA, Galib Y, Pantoja P, Colón L, González A, Tormos LM, Santana J, Luciano CA, González-Martínez J, Kraiselburd EN. Fatal granulomatous meningoencephalitis associated to mycobacterium mucogenicum-like microorganism: a case report. P R Health Sci J. 2009 Sep; 28(3):276-80.
9. Buch S, Gendelman H, Kraiselburd E. Tribute to Bill Narayan. J Med Primatol. 2008 Dec; 37 Suppl 2:5.
10. Wojna V, Skolasky RL, McArthur JC, Maldonado E, Hechavarria R, Mayo R, Selnes O, Ginebra T, de la Torre T, Garcia H, Kraiselburd E, Melendez-Guerrero LM, Zorrilla CD, Nath A. Spanish validation of the HIV dementia scale in women. AIDS Patient Care STDS. 2007 Dec; 21(12):930-41.
11. Aidoo M, Otten RA, Rodriguez V, Sariol CA, Martinez M, Kraiselburd E, Robinson H, Folks T, Butera S, Ellenberger D. Absence of SHIV infection in gut and lymph node tissues in rhesus monkeys after repeated rectal challenges following HIV-1 DNA/MVA immunizations. Vaccine. 2007 Aug 29; 25(35):6474-81.
12. Sariol CA, Muñoz-Jordán JL, Abel K, Rosado LC, Pantoja P, Giavedoni L, Rodriguez IV, White LJ, Martínez M, Arana T, Kraiselburd EN. Transcriptional activation of interferon-stimulated genes but not of cytokine genes after primary infection of rhesus macaques with dengue virus type 1. Clin Vaccine Immunol. 2007 Jun; 14(6):756-66.
13. Sariol CA, González-Martínez J, Arana T, Gascot S, Suárez E, Maldonado E, Gerald MS, Rodríguez M, Kraiselburd EN. Differential distribution of antibodies to different viruses in young animals in the free-ranging rhesus macaques of Cayo Santiago. J Med Primatol. 2006 Dec; 35(6):369-75.
14. Wojna V, Skolasky RL, Hechavarría R, Mayo R, Selnes O, McArthur JC, Meléndez LM, Maldonado E, Zorrilla CD, García H, Kraiselburd E, Nath A. Prevalence of human immunodeficiency virus-associated cognitive impairment in a group of Hispanic women at risk for neurological impairment. J Neurovirol. 2006 Oct; 12(5):356-64.
15. Waitt C, Gerald MS, Little AC, Kraiselburd E. Selective attention toward female secondary sexual color in male rhesus macaques. Am J Primatol. 2006 Jul; 68(7):738-44.
16. Ellenberger D, Otten RA, Li B, Aidoo M, Rodriguez IV, Sariol CA, Martinez M, Monsour M, Wyatt L, Hudgens MG, Kraiselburd E, Moss B, Robinson H, Folks T, Butera S. HIV-1 DNA/MVA vaccination reduces the per exposure probability of infection during repeated mucosal SHIV challenges. Virology. 2006 Aug 15; 352(1):216-25.
17. Ellenberger D, Wyatt L, Li B, Buge S, Lanier N, Rodriguez IV, Sariol CA, Martinez M, Monsour M, Vogt J, Smith J, Otten R, Montefiori D, Kraiselburd E, Moss B, Robinson H, McNicholl J, Butera S. Comparative immunogenicity in rhesus monkeys of multi-protein HIV-1 (CRF02_AG) DNA/MVA vaccines expressing mature and immature VLPs. Virology. 2005 Sep 15; 340(1):21-32.
18. Kumar R, Perez-Casanova AE, Tirado G, Noel RJ, Torres C, Rodriguez I, Martinez M, Staprans S, Kraiselburd E, Yamamura Y, Higley JD, Kumar A. Increased viral replication in simian immunodeficiency virus/simian-HIV-infected macaques with self-administering model of chronic alcohol consumption. J Acquir Immune Defic Syndr. 2005 Aug 01; 39(4):386-90.
19. Sariol CA, Arana T, Maldonado E, Gerald M, Gonzalez-Martinez J, Rodriguez M, Kraiselburd EN. Herpes B-virus seroreactivity in a colony of Macaca mulatta: data from the Sabana Seca Field Station, a new specific pathogen-free program. J Med Primatol. 2005 Feb; 34(1):13-9.
20. Kumar R, Torres C, Yamamura Y, Rodriguez I, Martinez M, Staprans S, Donahoe RM, Kraiselburd E, Stephens EB, Kumar A. Modulation by morphine of viral set point in rhesus macaques infected with simian immunodeficiency virus and simian-human immunodeficiency virus. J Virol. 2004 Oct; 78(20):11425-8.
21. Jensen K, Alvarado-Ramy F, González-Martínez J, Kraiselburd E, Rullán J. B-virus and free-ranging macaques, Puerto Rico. Emerg Infect Dis. 2004 Mar; 10(3):494-6.
22. Wojna V, Carlson KA, Luo X, Mayo R, Meléndez LM, Kraiselburd E, Gendelman HE. Proteomic fingerprinting of human immunodeficiency virus type 1-associated dementia from patient monocyte-derived macrophages: A case study. J Neurovirol. 2004; 10 Suppl 1:74-81.
23. O''Neill E, Bostik V, Montefiori DC, Kraiselburd E, Villinger F. IL-12/GM-CSF coadministration in an SIV DNA prime/protein boost protocol enhances Gag-specific T cells but not virus-specific neutralizing antibodies in rhesus macaques. AIDS Res Hum Retroviruses. 2003 Oct; 19(10):883-90.
24. O''Neill E, Martinez I, Villinger F, Rivera M, Gascot S, Colon C, Arana T, Sidhu M, Stout R, Montefiori DC, Martinez M, Ansari AA, Israel ZR, Kraiselburd E. Protection by SIV VLP DNA prime/protein boost following mucosal SIV challenge is markedly enhanced by IL-12/GM-CSF co-administration. J Med Primatol. 2002 Aug; 31(4-5):217-27.
25. Martínez I, Giavedoni L, Kraiselburd E. Clone B7 cells have a single copy of SIVsmB7 integrated in chromosome 20. Arch Virol. 2002; 147(1):217-23.
26. Kraiselburd EN, Salaman A, Beltrán M, Rivera M, Oliver J, Kessler M, Knezevich M, Rodriguez A, Bilska M, Montefiori D, Torres-Bauza LJ, Martinez I. Vaccine evaluation studies of replication-defective SIVsmB7. Cell Mol Biol (Noisy-le-grand). 1997 Nov; 43(7):915-24.
27. Kraiselburd EN, Torres JV. Properties of virus-like particles produced by SIV-chronically infected human cell clones. Cell Mol Biol (Noisy-le-grand). 1995; 41 Suppl 1:S41-52.
28. Málaga CA, Kraiselburd E, Lavergne JA, Del Llano AM, Amieiro JP. [Brief history of AIDS in non-human primates and its contribution to the study of acquired immunodeficiency syndrome]. P R Health Sci J. 1993 Apr; 12(1):47-54.
29. Béress A, Wassermann O, Tahhan S, Bruhn T, Béress L, Kraiselburd EN, Gonzalez LV, de Motta GE, Chavez PI. A new procedure for the isolation of anti-HIV compounds (polysaccharides and polyphenols) from the marine alga Fucus vesiculosus. J Nat Prod. 1993 Apr; 56(4):478-88.
30. del Llano AM, Amieiro-Puig JP, Kraiselburd EN, Kessler MJ, Málaga CA, Lavergne JA. The combined assessment of cellular apoptosis, mitochondrial function and proliferative response to pokeweed mitogen has prognostic value in SIV infection. J Med Primatol. 1993 Feb-May; 22(2-3):147-53.
31. Díaz AM, Frontera R, Kraiselburd E. Production of monoclonal antibodies to human immunodeficiency virus type-2. P R Health Sci J. 1992 Dec; 11(3):129-34.
32. Kraiselburd EN, Williams DC, Kessler MJ. In vitro HIV infection of primate lymphocytes. P R Health Sci J. 1990 Aug; 9(2):161-4.
33. Kouri YH, González L, Pérez M, Menar R, Gadea CR, Kraiselburd E, Torres-Bauza LJ. Effect of penicillin and spectinomycin given for urethritis and cervicitis with Neisseria gonorrhoeae: high prevalence of penicillin-resistant isolates. Genitourin Med. 1989 Oct; 65(5):342-6.
34. Kraiselburd EN, Gadea C, Torres-bauza LJ. Interactions of HIV and STDs in a group of female prostitutes. Arch AIDS Res. 1989; 3(1-3):149-57.
35. Innis BL, Eckels KH, Kraiselburd E, Dubois DR, Meadors GF, Gubler DJ, Burke DS, Bancroft WH. Virulence of a live dengue virus vaccine candidate: a possible new marker of dengue virus attenuation. J Infect Dis. 1988 Oct; 158(4):876-80.
36. Kraiselburd E. Dengue virus vaccine studies in Puerto Rico: a review. P R Health Sci J. 1987 Apr; 6(1):27-9.
37. Kraiselburd E, Gubler DJ, Kessler MJ. Quantity of dengue virus required to infect rhesus monkeys. Trans R Soc Trop Med Hyg. 1985; 79(2):248-51.
38. Kraiselburd E, Kessler MJ, Torres-Blasini G. Lack of viraemia and limited antibody response of dengue virus immune rhesus monkeys after vaccination with DEN-2/S-1 vaccine. Trans R Soc Trop Med Hyg. 1984; 78(4):445-8.
39. Balachandran N, Frame B, Chernesky M, Kraiselburd E, Kouri Y, Garcia D, Lavery C, Rawls WE. Identification and typing of herpes simplex viruses with monoclonal antibodies. J Clin Microbiol. 1982 Jul; 16(1):205-8.
40. Kraiselburd EN, Lavergne JA, Woodall JP, Kessler MJ, Meier G, Chiriboga J, Moore CG, Sather GE, Pomales A, Maldonado E, Rivera R. Lack of greater seroconversion of rhesus monkeys after subcutaneous inoculation of dengue type 2 live-virus vaccine combined with infection-enhancing antibodies. Infect Immun. 1981 Aug; 33(2):389-94.

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