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1.
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| 2011 | ADMINISTRATIVE CORE | 5G12RR003059-22 |  |
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| Application ID: | 8357140 |
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| Budget Period: | 07/01/2011 - 06/30/2012 |
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| Project Period: | 07/01/2011 - 06/30/2012 |
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| Award Notice Date: | 07/10/2011 |
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| Funding Mechanism: | Research Centers |
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| Department/ Organization Type: | SCH ALLIED HEALTH PROFESSIONS - NONE |
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| Administering Institutes or Centers: | NATIONAL CENTER FOR RESEARCH RESOURCES |
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| Awardee Organization: | TUSKEGEE UNIVERSITY |
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| Total Cost: | |
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| Spending Categories: |
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This subproject is one of many research subprojects utilizing the resources
provided by a Center grant funded by NIH/NCRR. Primary support for the subproject
and the subproject's principal investigator may have been provided by other sources,
including other NIH sources. The Total Cost listed for the subproject likely
represents the estimated amount of Center infrastructure utilized by the subproject,
not direct funding provided by the NCRR grant to the subproject or subproject staff.
The Center for Biomedical Research (CBR) administrative component supports and enhances the biomedical research infrastructure and facilitates meeting the objectives and goals of the RCMI program. The staff of the CBR provides broad support services to faculty engaged in biomedical research, and oversees the administration and management of RCMI program activities. The CBR strengthens Tuskegee University's (TU) research infrastructure by promoting Biomedical Research and fostering growth of the PhD Program in Integrative Biosciences. The CBR accomplishes these goals by integrating theoretical with practical concepts to: a) advance interdisciplinary research with mentored relationships between senior and junior faculty at TU and abroad, b) increase and improve communication within the University and with external agencies to facilitate faculty success in obtaining extramural support, c) strengthen support services offered by the CBR and increase proposals, publications, and manuscript development by providing un-interrupted molecular and digital microscopy infrastructure to pilot project investigators, d) strengthen research application management, development and administration, e) enhance communication between the University administration and academic units, f) sponsor seminars, symposia and other activities that expose faculty, trainees and students to the latest biomedical findings, and g) mentor faculty into independent grant application development by implementing an intramural review process. The CBR co-sponsored invited scholars'seminars, faculty research conferences and symposia by leading speakers from US top universities. Meetings and recommendations of the Internal and External Advisory Committees have resulted in improved communication and funding through indirect costs return, additional faculty, new equipment and collaborations with other research oriented universities.
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2.
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| 2010 | CENTER FOR BIOMEDICAL RESEARCH | 2G12RR003059-21A1 | |
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| Application ID: | 7942436 |
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| Budget Period: | 09/20/2010 - 06/30/2011 |
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| Project Period: | 07/07/1997 - 06/30/2015 |
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| Award Notice Date: | 09/16/2010 |
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| Funding Mechanism: | Research Centers |
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| Department/ Organization Type: | SCH ALLIED HEALTH PROFESSIONS - NONE |
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| Administering Institutes or Centers: | NATIONAL CENTER FOR RESEARCH RESOURCES |
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| Awardee Organization: | TUSKEGEE UNIVERSITY |
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| Total Cost: | $1,488,385 |
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| Spending Categories: |
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DESCRIPTION (provided by applicant): The TU Center for Biomedical Research (CBR) is designed to strengthen the University's research infrastructure particularly in the areas of biomedical and molecular sciences as well as in bioinformatics and computational biology. Our goals are to: 1) Continue to strengthen the newly established PhD program in Integrative Biosciences (IBS) through acquisition of state-of-the-art molecular biology instrumentation and bioinformatics and computer modeling resources;2) to promote health disparity studies in the underserved rural communities of the black belt counties (BBC) of Alabama. The specific aims are: A) To strengthen and provide oversight for infrastructure development composed of Core 1: State-of-the-art Molecular Biology Shareable Laboratory Resources, Core 2;Bioinformatics and Computational Modeling Resources. B) To support IBS PhD students, and provide the infrastructure needed to create a first rate biomedical research environment. C) Based on our current areas of scientific expertise, to initiate four pilot research projects to study prostate cancer, HIV/AIDS and lupus by a team of about 12 junior and senior scientists. D) To develop and implement a Mentoring/Evaluation Program for junior faculty, staff and students led and managed by the PD, and the Advisory Committees, E) To implement an Evaluation Program to assess the productivity and accountability of the CBR over a period of five years by using both formative and summative outcomes. The proposed research relies upon innovative methods to include in vitro (pilot #1, #2), in-vivo (pilot #2, #4) and computational dynamic modeling (pilot #3). The outcome is to increase the number of R01 or comparable research grant submissions by at least 50% from the current level of submissions and increasing publications in peer reviewed journals by at least 25% with an approved enforceable protocol that focuses on junior faculty development and productivity. The availability of advanced research equipment, coupled with the new knowledge generated via TU PhD students, scientists and collaborators will contribute to the reduction of selected health disparities in the BBC of Alabama.
PUBLIC HEALTH RELEVANCE (provided by applicant): Goal 2 of Healthy People 2010 states eliminating health disparities as a high priority agenda. Since our current expertise is in cancer, HIV/AIDS and lupus, our proposed project is focused upon these areas. Being a part of the black belt counties of Alabama where health disparities are of major concern, TU has a public health obligation and an opportunity for research and training directed at minimizing these disparities.
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3.
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| 2010 | ADMINISTRATIVE CORE | 2G12RR003059-21A1 | |
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| Application ID: | 8166228 |
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| Budget Period: | 09/20/2010 - 06/30/2011 |
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| Project Period: | 09/20/2010 - 06/30/2011 |
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| Award Notice Date: | 09/16/2010 |
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| Funding Mechanism: | Research Centers |
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| Department/ Organization Type: | SCH ALLIED HEALTH PROFESSIONS - NONE |
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| Administering Institutes or Centers: | NATIONAL CENTER FOR RESEARCH RESOURCES |
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| Awardee Organization: | TUSKEGEE UNIVERSITY |
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| Total Cost: | |
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| Spending Categories: |
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This subproject is one of many research subprojects utilizing the
resources provided by a Center grant funded by NIH/NCRR. The subproject and
investigator (PI) may have received primary funding from another NIH source,
and thus could be represented in other CRISP entries. The institution listed is
for the Center, which is not necessarily the institution for the investigator.
The Center for Biomedical Research (CBR) administrative component supports and enhances the biomedical research infrastructure and facilitates meeting the objectives and goals of the RCMI program. The staff of the CBR provides broad support services to faculty engaged in biomedical research, and oversees the administration and management of RCMI program activities. The CBR strengthens Tuskegee University's (TU) research infrastructure by promoting Biomedical Research and fostering growth of the PhD Program in Integrative Biosciences. The CBR accomplishes these goals by integrating theoretical with practical concepts to: a) advance interdisciplinary research with mentored relationships between senior and junior faculty at TU and abroad, b) increase and improve communication within the University and with external agencies to facilitate faculty success in obtaining extramural support, c) strengthen support services offered by the CBR and increase proposals, publications, and manuscript development by providing un-interrupted molecular and digital microscopy infrastructure to pilot project investigators, d) strengthen research application management, development and administration, e) enhance communication between the University administration and academic units, f) sponsor seminars, symposia and other activities that expose faculty, trainees and students to the latest biomedical findings, and g) mentor faculty into independent grant application development by implementing an intramural review process. The CBR co-sponsored invited scholars'seminars, faculty research conferences and symposia by leading speakers from US top universities. Meetings and recommendations of the Internal and External Advisory Committees have resulted in improved communication and funding through indirect costs return, additional faculty, new equipment and collaborations with other research oriented universities.
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4.
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| 2010 | COMPUTATIONAL BIOLOGY &BIOINFORMATICS | 2G12RR003059-21A1 | |
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| Application ID: | 8166230 |
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| Budget Period: | 09/20/2010 - 06/30/2011 |
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| Project Period: | 09/20/2010 - 06/30/2011 |
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| Award Notice Date: | 09/16/2010 |
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| Funding Mechanism: | Research Centers |
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| Department/ Organization Type: | SCH ALLIED HEALTH PROFESSIONS - NONE |
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| Administering Institutes or Centers: | NATIONAL CENTER FOR RESEARCH RESOURCES |
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| Awardee Organization: | TUSKEGEE UNIVERSITY |
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| Total Cost: | |
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| Spending Categories: |
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This subproject is one of many research subprojects utilizing the
resources provided by a Center grant funded by NIH/NCRR. The subproject and
investigator (PI) may have received primary funding from another NIH source,
and thus could be represented in other CRISP entries. The institution listed is
for the Center, which is not necessarily the institution for the investigator.
This project focuses upon Infrastructure development in Computational Biology and Bioinformatics as part of the Core Resources at the Center for Biomedical Research (CBR) at Tuskegee University. Research involving advanced information technologies, the Internet and databases is crucial in examining and analyzing patterns of disease occurrence, genetic traits and molecular level dynamics including AIDS research.
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5.
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| 2009 | COMPUTATIONAL BIOLOGY &BIOINFORMATICS | 3G12RR003059-20S2 | |
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| Application ID: | 7959270 |
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| Budget Period: | 09/18/2009 - 05/31/2010 |
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| Project Period: | 09/18/2009 - 05/31/2010 |
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| Award Notice Date: | 09/17/2009 |
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| Funding Mechanism: | Research Centers |
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| Department/ Organization Type: | UNIVERSITY-WIDE - NONE |
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| Administering Institutes or Centers: | NATIONAL CENTER FOR RESEARCH RESOURCES |
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| Awardee Organization: | TUSKEGEE UNIVERSITY |
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| Total Cost: | |
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| Spending Categories: |
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This subproject is one of many research subprojects utilizing the
resources provided by a Center grant funded by NIH/NCRR. The subproject and
investigator (PI) may have received primary funding from another NIH source,
and thus could be represented in other CRISP entries. The institution listed is
for the Center, which is not necessarily the institution for the investigator.
This project focuses upon Infrastructure development in Computational Biology and Bioinformatics as part of the Core Resources at the Center for Biomedical Research (CBR) at Tuskegee University. Research involving advanced information technologies, the Internet and databases is crucial in examining and analyzing patterns of disease occurrence, genetic traits and molecular level dynamics. The key strategy in our endeavors in the core Bioinformatics is to upgrade and strengthen the infrastructure and expertise of our scientists in computational biology and bioinformatics, acquire advanced computational and network resources and promote active research that exploits these technologies in health disparity studies. Server Development: Currently we have four servers: Three Red Hat Enterprise Linux ES and one Microsoft 2003 server. The software on the servers is accessible to computers on the campus. Website development: We have developed and continued to upgrade the following websites:
a) TU's RCMI website: http://compepid.tuskegee.edu/rcmi/RCMITu.htm.
b)The College of Veterinary Medicine, Nursing and Allied Health (CVMNAH) website http://www.onemedicine.tuskegee.edu.
c) The health disparities website http://www.healthdisparity.tuskegee.edu. He site has rich resources of health disparity databases for the 12 black belt counties of AL.
d) The data warehouse website http://www.onemedicinedb.tuskegee.edu. The Data Warehouse Directory helps our users to navigate through the information contained in CVMNAH's Data Warehouse. One objective of this data warehouse is to develop and implement an evaluation program to assess the productivity and accountability of the CVMNAH. The data warehouse will be used as a tracking systems to enable CVMNAH respond to internal and external demands for accountability with tangible measurements of productivity both for students'progress and institutional outcomes assessment. This also has an online application for admission into the CVMNAH.
e) The Bioinformatics website, under the TU's RCMI website, has a rich variety of selected resources in different categories and data which can be used by scientists interested in the area of bioinformatics and health disparities http://compepid.tuskegee.edu/rcmi/RCMI.htm. The Annual Biomedical Research Symposium: As part of the strategy to promote sharing of biomedical research activities that are in progress as well as to address national issues dealing with Health Disparities, CCEBRA organized ten annual biomedical research symposia which were held during the last week of every September at the Kellogg Conference Center, Tuskegee University. Shared Resource: CCEBRA has been providing service in statistical analysis for faculty and researchers at TU in addition to statistical support for graduate students. NCBI field guide in Tuskegee University: CCEBRA at TU previously hosted two courses entitled "A Field Guide to GenBank and NCBI Molecular Biology Resources" we anticipate to host them again when they resume offering them. The National Center for Biotechnology Information (NCBI), a division of the National Library of Medicine offered the courses and they were given by instructors from NCBI. See the sample at: http://compepid.tuskegee.edu/rgsevents/NCBI2006/NCBITu.htm.
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6.
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| 2009 | APPLYING BIOINFORMATICS AND COMPUTATIONAL BIOLOGY TO STUDY HIV/AIDS | 3G12RR003059-20S2 | |
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| Application ID: | 7959271 |
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| Budget Period: | 09/18/2009 - 05/31/2010 |
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| Project Period: | 09/18/2009 - 05/31/2010 |
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| Award Notice Date: | 09/17/2009 |
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| Funding Mechanism: | Research Centers |
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| Department/ Organization Type: | UNIVERSITY-WIDE - NONE |
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| Administering Institutes or Centers: | NATIONAL CENTER FOR RESEARCH RESOURCES |
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| Awardee Organization: | TUSKEGEE UNIVERSITY |
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| Total Cost: | |
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| Spending Categories: |
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This subproject is one of many research subprojects utilizing the
resources provided by a Center grant funded by NIH/NCRR. The subproject and
investigator (PI) may have received primary funding from another NIH source,
and thus could be represented in other CRISP entries. The institution listed is
for the Center, which is not necessarily the institution for the investigator.
This project focuses upon Research in Computational Epidemiology with an emphasis on a health disparity disease of major concern, that of HIV/AIDS. SPECIFIC AIMS: 1) Development of a novel micro-epidemiologic computational model for HIV/AIDS at the intracellular level: The model was developed to provide insights in how an intracellular/molecular level model can be incorporated within a macro-epidemiologic integrative systems dynamics model for examining a variety of computational experimentations. 2) Development of a systems dynamics model and modelling of the multifactorial epidemiology of HIV/AIDS. An epidemiologic model that incorporates cellular/molecular (micro level) and macro level epidemiologic dynamics for examining preventive and therapeutic strategies of HIV/AIDS in African American sub populations was developed. 3) Modelling of the multifactorial epidemiology of HIV/AIDS: Multifactorial and quantitative epidemiologic studies that interrelate (biomedical, behavioral, and socioeconomic factors) determinants have been developed. Using these models as our experimental medium, we evaluate various intervention scenarios to recommend effective strategies for the community to minimize the risk of new infections prevent future infections and manage existing infections. 4) Static modeling to examine if HAART Therapies for HIV/AIDS. To answer the question of which combination of HAART is most effective we collaborated with the University of Alabama at Birmingham (UAB) 1917 HIV/AIDS clinic. Although the results of this study appeared promising in the beginning, they did not provide clear and reliable outcomes.
STUDIES AND RESULTS: Manuscripts are being prepared for submission to journals. PLANS: To continue analyzing data, gathering more data and information for the estimation of the parameters and variables of the model for HIV/AIDS with a focus on the macro-epidemiology of AIDS in African Americans.
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7.
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| 2009 | CENTER FOR BIOMEDICAL RESEARCH | 3G12RR003059-20S2 | |
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| Application ID: | 7921215 |
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| Budget Period: | 09/18/2009 - 09/19/2010 |
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| Project Period: | 06/01/1988 - 09/19/2010 |
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| Award Notice Date: | 09/17/2009 |
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| Funding Mechanism: | Research Centers |
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| Department/ Organization Type: | UNIVERSITY-WIDE - NONE |
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| Administering Institutes or Centers: | NATIONAL CENTER FOR RESEARCH RESOURCES |
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| Awardee Organization: | TUSKEGEE UNIVERSITY |
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| Total Cost: | $578,685 |
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| Spending Categories: |
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Overall Summary: Center for Biomedical Research/Research Centers at Minority Institutions
This proposal presents Tuskegee University's plan to continue development and strengthening of its RCMI supported Center for Biomedical Research (CBR). The existing and planned infrastructure in biomedical, molecular, and information technology plays a critical role in the University's plans to meet the health care challenges facing minorities in the 21 st century. The proposal was developed after institutional analysis of strengths and needs in biomedical research following Southern Association of Colleges and Schools and American Veterinary Medical Association accreditation and strategic planning. The overreaching goals of the proposal are to: 1) continue to support and strengthen biomedical research infrastructure;2) assist in supporting the implementation of the new Ph. D. program in Integrative Biosciences;3) promote mechanisms to institutionalize the CBR/RCMI program;4) support individual developmental research projects in areas having significant health related impact on minority populations. This proposal builds on the vision of approaching minority health problems through five significant areas. These are bioinformatics and computational epidemiology, cancer, environmental toxicology, and immunology. These four areas of research examine specific diseases and basic principles, which disproportionately impact minority, especially African American, populations.
This proposal has a section describing the overall nature of the institution and future goals of the
University and the interrelationship between the CBR/RCMI program and the Ph. D. program, an
Administrative section, a Core Facility section describing the existing biomedical research infrastructure (CBR/RCMI supported) and developmental plans for those facilities, and individual developmental proposals in the biomedical areas listed above. The implementation of the Core Facility and individual project proposals will enhance the ability of Tuskegee University faculty to compete in the biomedical research arena. Enhanced competition by Tuskegee faculty will improve the understanding of and conditions effecting the health care of minorities.
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8.
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| 2008 | CENTER FOR BIOMEDICAL RESEARCH | 3G12RR003059-20S1 | |
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| Application ID: | 7674881 |
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| Budget Period: | 09/16/2008 - 05/31/2009 |
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| Project Period: | 06/01/1988 - 05/31/2009 |
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| Award Notice Date: | 2008-09-16 |
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| Funding Mechanism: | |
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| Department/ Organization Type: | UNIVERSITY-WIDE - NONE |
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| Administering Institutes or Centers: | NATIONAL CENTER FOR RESEARCH RESOURCES |
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| Awardee Organization: | TUSKEGEE UNIVERSITY |
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| Total Cost: | $602,476 |
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| Spending Categories: |
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Overall Summary: Center for Biomedical Research/Research Centers at Minority Institutions
This proposal presents Tuskegee University's plan to continue development and strengthening of its RCMI supported Center for Biomedical Research (CBR). The existing and planned infrastructure in biomedical, molecular, and information technology plays a critical role in the University's plans to meet the health care challenges facing minorities in the 21 st century. The proposal was developed after institutional analysis of strengths and needs in biomedical research following Southern Association of Colleges and Schools and American Veterinary Medical Association accreditation and strategic planning. The overreaching goals of the proposal are to: 1) continue to support and strengthen biomedical research infrastructure; 2) assist in supporting the implementation of the new Ph. D. program in Integrative Biosciences; 3) promote mechanisms to institutionalize the CBR/RCMI program; 4) support individual developmental research projects in areas having significant health related impact on minority populations. This proposal builds on the vision of approaching minority health problems through five significant areas. These are bioinformatics and computational epidemiology, cancer, environmental toxicology, and immunology. These four areas of research examine specific diseases and basic principles, which disproportionately impact minority, especially African American, populations.
This proposal has a section describing the overall nature of the institution and future goals of the
University and the interrelationship between the CBR/RCMI program and the Ph. D. program, an
Administrative section, a Core Facility section describing the existing biomedical research infrastructure (CBR/RCMI supported) and developmental plans for those facilities, and individual developmental proposals in the biomedical areas listed above. The implementation of the Core Facility and individual project proposals will enhance the ability of Tuskegee University faculty to compete in the biomedical research arena. Enhanced competition by Tuskegee faculty will improve the understanding of and conditions effecting the health care of minorities.
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9.
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| 2008 | COMPUTATIONAL BIOLOGY &BIOINFORMATICS | 3G12RR003059-20S1 | |
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| Application ID: | 7715381 |
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| Budget Period: | 09/16/2008 - 05/31/2009 |
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| Project Period: | 09/16/2008 - 05/31/2009 |
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| Award Notice Date: | 2008-09-16 |
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| Funding Mechanism: | |
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| Department/ Organization Type: | UNIVERSITY-WIDE - NONE |
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| Administering Institutes or Centers: | NATIONAL CENTER FOR RESEARCH RESOURCES |
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| Awardee Organization: | TUSKEGEE UNIVERSITY |
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| Total Cost: | |
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10.
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| 2008 | APPLYING BIOINFORMATICS AND COMPUTATIONAL BIOLOGY TO STUDY HIV/AIDS | 3G12RR003059-20S1 | |
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| Application ID: | 7715382 |
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| Budget Period: | 09/16/2008 - 05/31/2009 |
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| Project Period: | 09/16/2008 - 05/31/2009 |
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| Award Notice Date: | 2008-09-16 |
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| Funding Mechanism: | |
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| Department/ Organization Type: | UNIVERSITY-WIDE - NONE |
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| Administering Institutes or Centers: | NATIONAL CENTER FOR RESEARCH RESOURCES |
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| Awardee Organization: | TUSKEGEE UNIVERSITY |
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| Total Cost: | |
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| Spending Categories: |
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11.
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| 2007 | CENTER FOR BIOMEDICAL RESEARCH | 5G12RR003059-20 | |
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| Application ID: | 7247132 |
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| Budget Period: | 06/01/2007 - 05/31/2010 |
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| Project Period: | 06/01/1988 - 05/31/2010 |
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| Award Notice Date: | 2007-06-06 |
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| Funding Mechanism: | |
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| Department/ Organization Type: | UNIVERSITY-WIDE - NONE |
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| Administering Institutes or Centers: | NATIONAL CENTER FOR RESEARCH RESOURCES |
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| Awardee Organization: | TUSKEGEE UNIVERSITY |
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| Total Cost: | $1,132,198 |
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| Spending Categories: |
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Overall Summary: Center for Biomedical Research/Research Centers at Minority Institutions
This proposal presents Tuskegee University's plan to continue development and strengthening of its RCMI supported Center for Biomedical Research (CBR). The existing and planned infrastructure in biomedical, molecular, and information technology plays a critical role in the University's plans to meet the health care challenges facing minorities in the 21 st century. The proposal was developed after institutional analysis of strengths and needs in biomedical research following Southern Association of Colleges and Schools and American Veterinary Medical Association accreditation and strategic planning. The overreaching goals of the proposal are to: 1) continue to support and strengthen biomedical research infrastructure; 2) assist in supporting the implementation of the new Ph. D. program in Integrative Biosciences; 3) promote mechanisms to institutionalize the CBR/RCMI program; 4) support individual developmental research projects in areas having significant health related impact on minority populations. This proposal builds on the vision of approaching minority health problems through five significant areas. These are bioinformatics and computational epidemiology, cancer, environmental toxicology, and immunology. These four areas of research examine specific diseases and basic principles, which disproportionately impact minority, especially African American, populations.
This proposal has a section describing the overall nature of the institution and future goals of the
University and the interrelationship between the CBR/RCMI program and the Ph. D. program, an
Administrative section, a Core Facility section describing the existing biomedical research infrastructure (CBR/RCMI supported) and developmental plans for those facilities, and individual developmental proposals in the biomedical areas listed above. The implementation of the Core Facility and individual project proposals will enhance the ability of Tuskegee University faculty to compete in the biomedical research arena. Enhanced competition by Tuskegee faculty will improve the understanding of and conditions effecting the health care of minorities.
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12.
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| 2007 | COMPUTATIONAL BIOLOGY &BIOINFORMATICS | 5G12RR003059-20 | |
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| Application ID: | 7561450 |
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| Budget Period: | 06/01/2007 - 05/31/2008 |
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| Project Period: | 06/01/2007 - 05/31/2008 |
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| Award Notice Date: | 2007-06-06 |
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| Funding Mechanism: | |
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| Department/ Organization Type: | UNIVERSITY-WIDE - NONE |
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| Administering Institutes or Centers: | NATIONAL CENTER FOR RESEARCH RESOURCES |
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| Awardee Organization: | TUSKEGEE UNIVERSITY |
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| Total Cost: | |
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| Spending Categories: |
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13.
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| 2007 | APPLYING BIOINFORMATICS AND COMPUTATIONAL BIOLOGY TO STUDY HIV/AIDS | 5G12RR003059-20 | |
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| Application ID: | 7561451 |
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| Budget Period: | 06/01/2007 - 05/31/2008 |
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| Project Period: | 06/01/2007 - 05/31/2008 |
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| Award Notice Date: | 2007-06-06 |
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| Funding Mechanism: | |
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| Department/ Organization Type: | UNIVERSITY-WIDE - NONE |
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| Administering Institutes or Centers: | NATIONAL CENTER FOR RESEARCH RESOURCES |
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| Awardee Organization: | TUSKEGEE UNIVERSITY |
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| Total Cost: | |
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14.
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| 2006 | COMPUTATIONAL BIOLOGY &BIOINFORMATICS | 5G12RR003059-19 | |
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| Application ID: | 7336051 |
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| Budget Period: | 06/01/2006 - 05/31/2007 |
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| Project Period: | 06/01/2006 - 05/31/2007 |
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| Award Notice Date: | 2006-06-14 |
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| Funding Mechanism: | |
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| Department/ Organization Type: | UNIVERSITY-WIDE - NONE |
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| Administering Institutes or Centers: | NATIONAL CENTER FOR RESEARCH RESOURCES |
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| Awardee Organization: | TUSKEGEE UNIVERSITY |
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| Total Cost: | |
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| Spending Categories: |
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15.
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| 2006 | APPLYING BIOINFORMATICS AND COMPUTATIONAL BIOLOGY TO STUDY HIV/AIDS | 5G12RR003059-19 | |
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| Application ID: | 7336052 |
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| Budget Period: | 06/01/2006 - 05/31/2007 |
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| Project Period: | 06/01/2006 - 05/31/2007 |
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| Award Notice Date: | 2006-06-14 |
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| Funding Mechanism: | |
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| Department/ Organization Type: | UNIVERSITY-WIDE - NONE |
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| Administering Institutes or Centers: | NATIONAL CENTER FOR RESEARCH RESOURCES |
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| Awardee Organization: | TUSKEGEE UNIVERSITY |
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| Total Cost: | |
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| Spending Categories: |
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16.
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| 2006 | CENTER FOR BIOMEDICAL RESEARCH | 5G12RR003059-19 | |
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| Application ID: | 7101051 |
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| Budget Period: | 06/01/2006 - 05/31/2007 |
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| Project Period: | 06/01/1988 - 05/31/2008 |
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| Award Notice Date: | 2006-06-14 |
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| Funding Mechanism: | |
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| Department/ Organization Type: | UNIVERSITY-WIDE - NONE |
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| Administering Institutes or Centers: | NATIONAL CENTER FOR RESEARCH RESOURCES |
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| Awardee Organization: | TUSKEGEE UNIVERSITY |
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| Total Cost: | $643,202 |
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| Spending Categories: |
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Overall Summary: Center for Biomedical Research/Research Centers at Minority Institutions
This proposal presents Tuskegee University's plan to continue development and strengthening of its RCMI supported Center for Biomedical Research (CBR). The existing and planned infrastructure in biomedical, molecular, and information technology plays a critical role in the University's plans to meet the health care challenges facing minorities in the 21 st century. The proposal was developed after institutional analysis of strengths and needs in biomedical research following Southern Association of Colleges and Schools and American Veterinary Medical Association accreditation and strategic planning. The overreaching goals of the proposal are to: 1) continue to support and strengthen biomedical research infrastructure; 2) assist in supporting the implementation of the new Ph. D. program in Integrative Biosciences; 3) promote mechanisms to institutionalize the CBR/RCMI program; 4) support individual developmental research projects in areas having significant health related impact on minority populations. This proposal builds on the vision of approaching minority health problems through five significant areas. These are bioinformatics and computational epidemiology, cancer, environmental toxicology, and immunology. These four areas of research examine specific diseases and basic principles, which disproportionately impact minority, especially African American, populations.
This proposal has a section describing the overall nature of the institution and future goals of the
University and the interrelationship between the CBR/RCMI program and the Ph. D. program, an
Administrative section, a Core Facility section describing the existing biomedical research infrastructure (CBR/RCMI supported) and developmental plans for those facilities, and individual developmental proposals in the biomedical areas listed above. The implementation of the Core Facility and individual project proposals will enhance the ability of Tuskegee University faculty to compete in the biomedical research arena. Enhanced competition by Tuskegee faculty will improve the understanding of and conditions effecting the health care of minorities.
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17.
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| 2004 | COMPUTATIONAL BIOLOGY &BIOINFORMATICS | 5G12RR003059-17 | |
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| Application ID: | 7011431 |
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| Budget Period: | 06/01/2004 - 05/31/2005 |
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| Project Period: | 06/01/2004 - 05/31/2005 |
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| Award Notice Date: | 2004-07-19T14:33:00 |
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| Funding Mechanism: | |
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| Department/ Organization Type: | UNIVERSITY-WIDE - NONE |
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| Administering Institutes or Centers: | NATIONAL CENTER FOR RESEARCH RESOURCES |
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| Awardee Organization: | TUSKEGEE UNIVERSITY |
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| Total Cost: | |
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| Spending Categories: |
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18.
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| 2004 | APPLYING BIOINFORMATICS AND COMPUTATIONAL BIOLOGY TO STUDY HIV/AIDS | 5G12RR003059-17 | |
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| Application ID: | 7011432 |
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| Budget Period: | 06/01/2004 - 05/31/2005 |
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| Project Period: | 06/01/2004 - 05/31/2005 |
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| Award Notice Date: | 2004-07-19T14:33:00 |
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| Funding Mechanism: | |
|---|
| Department/ Organization Type: | UNIVERSITY-WIDE - NONE |
|---|
| Administering Institutes or Centers: | NATIONAL CENTER FOR RESEARCH RESOURCES |
|---|
| Awardee Organization: | TUSKEGEE UNIVERSITY |
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| Total Cost: | |
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| Spending Categories: |
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19.
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| 2002 | COMPUTER MODEL DVMT: CELLULAR &POPULATION AIDS EPIDEMIOLOGY: AFRICAN AMERICANS | 3G12RR003059-14S2 | |
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| Application ID: | 6593141 |
|---|
| Budget Period: | - |
|---|
| Project Period: | 06/01/2001 - 05/31/2002 |
|---|
| Award Notice Date: | |
|---|
| Funding Mechanism: | |
|---|
| Department/ Organization Type: | - |
|---|
| Administering Institutes or Centers: | NATIONAL CENTER FOR RESEARCH RESOURCES |
|---|
| Awardee Organization: | TUSKEGEE UNIVERSITY |
|---|
| Total Cost: | |
|---|
| Spending Categories: |
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This project consists of three interrelated and complimentary
activities of biomedical computing infrastructure development,
research and outreach. The research component focuses on computer
based scientific experimentation currently referred to as
computational epidenuiology. The goal is to build on our existing
strength in the area of epidemiologic modeling and biomedical
information management systems. The research will emphasizes
integrative computational models for CD4+ lymphocyte populations and
HIV viral load interactions so as to examine the effect of
intervention (drug) therapies individually and/or in combinations.
The objectives are to: a) strengthen and expand the biomedical
computing infrastructure for research at Tuskegee University; b) carry
out research that combines theoretical and clinical HIV/CD4+ cell
population interactions and to use the computational models to
evaluate antiretroviral intervention strategies with a focus on
African Americans; and, c) provide outreach by creating a Virtual
Health Information Resource with a focus on the health of minorities,
relying on the Internet and the VAW as the primary- mode for
communication and information sharing. The project will proceed in
two phases. In Phase I (years 1-2), collaboration and database
development will be emphasized. Collaboration with the University of
Alabama Medical School, where extensive clinical HIV/AlDS studies are
being carried out, Wlill provide access to clinical and molecular
laboratory data that will be used in the modeling research.. In Phase
H (years 2-5), epidemiologic modeling research based on advanced comp
utational methods will be conducted. In both phases, an outreach and
infrastructure component to create a Virtual Health Information
Resource will be created. It will serve as a core resource to advance
biomedical sciences research and education; promote collaborative
research; enable access to digital information via the Internet and
the WWW and provide computational modeling laboratory for
undergraduate and graduate students including those who will be
pursuing PhD studies.
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20.
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| 2002 | COMPUTER MODEL DVMT: CELLULAR &POPULATION AIDS EPIDEMIOLOGY: AFRICAN AMERICANS | 5G12RR003059-15 | |
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| Application ID: | 6604786 |
|---|
| Budget Period: | - |
|---|
| Project Period: | 06/01/2002 - 05/31/2003 |
|---|
| Award Notice Date: | |
|---|
| Funding Mechanism: | |
|---|
| Department/ Organization Type: | - |
|---|
| Administering Institutes or Centers: | NATIONAL CENTER FOR RESEARCH RESOURCES |
|---|
| Awardee Organization: | TUSKEGEE UNIVERSITY |
|---|
| Total Cost: | |
|---|
| Spending Categories: |
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|---|
This project consists of three interrelated and complimentary
activities of biomedical computing infrastructure development,
research and outreach. The research component focuses on computer
based scientific experimentation currently referred to as
computational epidenuiology. The goal is to build on our existing
strength in the area of epidemiologic modeling and biomedical
information management systems. The research will emphasizes
integrative computational models for CD4+ lymphocyte populations and
HIV viral load interactions so as to examine the effect of
intervention (drug) therapies individually and/or in combinations.
The objectives are to: a) strengthen and expand the biomedical
computing infrastructure for research at Tuskegee University; b) carry
out research that combines theoretical and clinical HIV/CD4+ cell
population interactions and to use the computational models to
evaluate antiretroviral intervention strategies with a focus on
African Americans; and, c) provide outreach by creating a Virtual
Health Information Resource with a focus on the health of minorities,
relying on the Internet and the VAW as the primary- mode for
communication and information sharing. The project will proceed in
two phases. In Phase I (years 1-2), collaboration and database
development will be emphasized. Collaboration with the University of
Alabama Medical School, where extensive clinical HIV/AlDS studies are
being carried out, Wlill provide access to clinical and molecular
laboratory data that will be used in the modeling research.. In Phase
H (years 2-5), epidemiologic modeling research based on advanced comp
utational methods will be conducted. In both phases, an outreach and
infrastructure component to create a Virtual Health Information
Resource will be created. It will serve as a core resource to advance
biomedical sciences research and education; promote collaborative
research; enable access to digital information via the Internet and
the WWW and provide computational modeling laboratory for
undergraduate and graduate students including those who will be
pursuing PhD studies.
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21.
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| 2001 | COMPUTER MODEL DVMT: CELLULAR &POPULATION AIDS EPIDEMIOLOGY: AFRICAN AMERICANS | 5G12RR003059-14 | |
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|---|
| Application ID: | 6475069 |
|---|
| Budget Period: | 10/01/1998 - 09/30/1999 |
|---|
| Project Period: | 06/01/2001 - 05/31/2002 |
|---|
| Award Notice Date: | |
|---|
| Funding Mechanism: | |
|---|
| Department/ Organization Type: | - |
|---|
| Administering Institutes or Centers: | NATIONAL CENTER FOR RESEARCH RESOURCES |
|---|
| Awardee Organization: | TUSKEGEE UNIVERSITY |
|---|
| Total Cost: | |
|---|
| Spending Categories: |
|
|---|
This project consists of three interrelated and complimentary
activities of biomedical computing infrastructure development,
research and outreach. The research component focuses on computer
based scientific experimentation currently referred to as
computational epidenuiology. The goal is to build on our existing
strength in the area of epidemiologic modeling and biomedical
information management systems. The research will emphasizes
integrative computational models for CD4+ lymphocyte populations and
HIV viral load interactions so as to examine the effect of
intervention (drug) therapies individually and/or in combinations.
The objectives are to: a) strengthen and expand the biomedical
computing infrastructure for research at Tuskegee University; b) carry
out research that combines theoretical and clinical HIV/CD4+ cell
population interactions and to use the computational models to
evaluate antiretroviral intervention strategies with a focus on
African Americans; and, c) provide outreach by creating a Virtual
Health Information Resource with a focus on the health of minorities,
relying on the Internet and the VAW as the primary- mode for
communication and information sharing. The project will proceed in
two phases. In Phase I (years 1-2), collaboration and database
development will be emphasized. Collaboration with the University of
Alabama Medical School, where extensive clinical HIV/AlDS studies are
being carried out, Wlill provide access to clinical and molecular
laboratory data that will be used in the modeling research.. In Phase
H (years 2-5), epidemiologic modeling research based on advanced comp
utational methods will be conducted. In both phases, an outreach and
infrastructure component to create a Virtual Health Information
Resource will be created. It will serve as a core resource to advance
biomedical sciences research and education; promote collaborative
research; enable access to digital information via the Internet and
the WWW and provide computational modeling laboratory for
undergraduate and graduate students including those who will be
pursuing PhD studies.
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22.
|
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| 2001 | COMPUTER MODEL DVMT: CELLULAR &POPULATION AIDS EPIDEMIOLOGY: AFRICAN AMERICANS | 3G12RR003059-14S1 | |
|
|---|
| Application ID: | 6506356 |
|---|
| Budget Period: | - |
|---|
| Project Period: | 06/01/2001 - 05/31/2002 |
|---|
| Award Notice Date: | |
|---|
| Funding Mechanism: | |
|---|
| Department/ Organization Type: | - |
|---|
| Administering Institutes or Centers: | NATIONAL CENTER FOR RESEARCH RESOURCES |
|---|
| Awardee Organization: | TUSKEGEE UNIVERSITY |
|---|
| Total Cost: | |
|---|
| Spending Categories: |
|
|---|
This project consists of three interrelated and complimentary
activities of biomedical computing infrastructure development,
research and outreach. The research component focuses on computer
based scientific experimentation currently referred to as
computational epidenuiology. The goal is to build on our existing
strength in the area of epidemiologic modeling and biomedical
information management systems. The research will emphasizes
integrative computational models for CD4+ lymphocyte populations and
HIV viral load interactions so as to examine the effect of
intervention (drug) therapies individually and/or in combinations.
The objectives are to: a) strengthen and expand the biomedical
computing infrastructure for research at Tuskegee University; b) carry
out research that combines theoretical and clinical HIV/CD4+ cell
population interactions and to use the computational models to
evaluate antiretroviral intervention strategies with a focus on
African Americans; and, c) provide outreach by creating a Virtual
Health Information Resource with a focus on the health of minorities,
relying on the Internet and the VAW as the primary- mode for
communication and information sharing. The project will proceed in
two phases. In Phase I (years 1-2), collaboration and database
development will be emphasized. Collaboration with the University of
Alabama Medical School, where extensive clinical HIV/AlDS studies are
being carried out, Wlill provide access to clinical and molecular
laboratory data that will be used in the modeling research.. In Phase
H (years 2-5), epidemiologic modeling research based on advanced comp
utational methods will be conducted. In both phases, an outreach and
infrastructure component to create a Virtual Health Information
Resource will be created. It will serve as a core resource to advance
biomedical sciences research and education; promote collaborative
research; enable access to digital information via the Internet and
the WWW and provide computational modeling laboratory for
undergraduate and graduate students including those who will be
pursuing PhD studies.
|
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23.
|
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| 2000 | COMPUTER MODEL DVMT: CELLULAR &POPULATION AIDS EPIDEMIOLOGY: AFRICAN AMERICANS | 5G12RR003059-13 | |
|
|---|
| Application ID: | 6326185 |
|---|
| Budget Period: | 10/01/1998 - 09/30/1999 |
|---|
| Project Period: | 06/05/2000 - 05/31/2001 |
|---|
| Award Notice Date: | |
|---|
| Funding Mechanism: | |
|---|
| Department/ Organization Type: | - |
|---|
| Administering Institutes or Centers: | NATIONAL CENTER FOR RESEARCH RESOURCES |
|---|
| Awardee Organization: | TUSKEGEE UNIVERSITY |
|---|
| Total Cost: | |
|---|
| Spending Categories: |
|
|---|
This project consists of three interrelated and complimentary
activities of biomedical computing infrastructure development,
research and outreach. The research component focuses on computer
based scientific experimentation currently referred to as
computational epidenuiology. The goal is to build on our existing
strength in the area of epidemiologic modeling and biomedical
information management systems. The research will emphasizes
integrative computational models for CD4+ lymphocyte populations and
HIV viral load interactions so as to examine the effect of
intervention (drug) therapies individually and/or in combinations.
The objectives are to: a) strengthen and expand the biomedical
computing infrastructure for research at Tuskegee University; b) carry
out research that combines theoretical and clinical HIV/CD4+ cell
population interactions and to use the computational models to
evaluate antiretroviral intervention strategies with a focus on
African Americans; and, c) provide outreach by creating a Virtual
Health Information Resource with a focus on the health of minorities,
relying on the Internet and the VAW as the primary- mode for
communication and information sharing. The project will proceed in
two phases. In Phase I (years 1-2), collaboration and database
development will be emphasized. Collaboration with the University of
Alabama Medical School, where extensive clinical H1V/Al1DS studies are
being carried out, Wlill provide access to clinical and molecular
laboratory data that will be used in the modeling research.. In Phase
H (years 2-5), epidemiologic modeling research based on advanced comp
utational methods will be conducted. In both phases, an outreach and
infrastructure component to create a Virtual Health Information
Resource will be created. It will serve as a core resource to advance
biomedical sciences research and education; promote collaborative
research; enable access to digital information via the Internet and
the WWW and provide computational modeling laboratory for
undergraduate and graduate students including those who will be
pursuing PhD studies.
|
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24.
|
|
| 2000 | COMPUTER MODEL DVMT: CELLULAR &POPULATION AIDS EPIDEMIOLOGY: AFRICAN AMERICANS | 3G12RR003059-13S2 | |
|
|---|
| Application ID: | 6348006 |
|---|
| Budget Period: | 10/01/1998 - 09/30/1999 |
|---|
| Project Period: | 06/05/2000 - 05/31/2001 |
|---|
| Award Notice Date: | |
|---|
| Funding Mechanism: | |
|---|
| Department/ Organization Type: | - |
|---|
| Administering Institutes or Centers: | NATIONAL CENTER FOR RESEARCH RESOURCES |
|---|
| Awardee Organization: | TUSKEGEE UNIVERSITY |
|---|
| Total Cost: | |
|---|
| Spending Categories: |
|
|---|
This project consists of three interrelated and complimentary
activities of biomedical computing infrastructure development,
research and outreach. The research component focuses on computer
based scientific experimentation currently referred to as
computational epidenuiology. The goal is to build on our existing
strength in the area of epidemiologic modeling and biomedical
information management systems. The research will emphasizes
integrative computational models for CD4+ lymphocyte populations and
HIV viral load interactions so as to examine the effect of
intervention (drug) therapies individually and/or in combinations.
The objectives are to: a) strengthen and expand the biomedical
computing infrastructure for research at Tuskegee University; b) carry
out research that combines theoretical and clinical HIV/CD4+ cell
population interactions and to use the computational models to
evaluate antiretroviral intervention strategies with a focus on
African Americans; and, c) provide outreach by creating a Virtual
Health Information Resource with a focus on the health of minorities,
relying on the Internet and the VAW as the primary- mode for
communication and information sharing. The project will proceed in
two phases. In Phase I (years 1-2), collaboration and database
development will be emphasized. Collaboration with the University of
Alabama Medical School, where extensive clinical HIV/AlDS studies are
being carried out, Wlill provide access to clinical and molecular
laboratory data that will be used in the modeling research.. In Phase
H (years 2-5), epidemiologic modeling research based on advanced comp
utational methods will be conducted. In both phases, an outreach and
infrastructure component to create a Virtual Health Information
Resource will be created. It will serve as a core resource to advance
biomedical sciences research and education; promote collaborative
research; enable access to digital information via the Internet and
the WWW and provide computational modeling laboratory for
undergraduate and graduate students including those who will be
pursuing PhD studies.
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25.
|
|
| 1999 | COMPUTER MODEL DVMT: CELLULAR &POPULATION AIDS EPIDEMIOLOGY: AFRICAN AMERICANS | 5G12RR003059-12 | |
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|---|
| Application ID: | 6121527 |
|---|
| Budget Period: | 10/01/1998 - 09/30/1999 |
|---|
| Project Period: | 06/01/1999 - 05/31/2000 |
|---|
| Award Notice Date: | |
|---|
| Funding Mechanism: | |
|---|
| Department/ Organization Type: | - |
|---|
| Administering Institutes or Centers: | NATIONAL CENTER FOR RESEARCH RESOURCES |
|---|
| Awardee Organization: | TUSKEGEE UNIVERSITY |
|---|
| Total Cost: | |
|---|
| Spending Categories: |
|
|---|
This project consists of three interrelated and complimentary
activities of biomedical computing infrastructure development,
research and outreach. The research component focuses on computer
based scientific experimentation currently referred to as
computational epidenuiology. The goal is to build on our existing
strength in the area of epidemiologic modeling and biomedical
information management systems. The research will emphasizes
integrative computational models for CD4+ lymphocyte populations and
HIV viral load interactions so as to examine the effect of
intervention (drug) therapies individually and/or in combinations.
The objectives are to: a) strengthen and expand the biomedical
computing infrastructure for research at Tuskegee University; b) carry
out research that combines theoretical and clinical HIV/CD4+ cell
population interactions and to use the computational models to
evaluate antiretroviral intervention strategies with a focus on
African Americans; and, c) provide outreach by creating a Virtual
Health Information Resource with a focus on the health of minorities,
relying on the Internet and the VAW as the primary- mode for
communication and information sharing. The project will proceed in
two phases. In Phase I (years 1-2), collaboration and database
development will be emphasized. Collaboration with the University of
Alabama Medical School, where extensive clinical H1V/Al1DS studies are
being carried out, Wlill provide access to clinical and molecular
laboratory data that will be used in the modeling research.. In Phase
H (years 2-5), epidemiologic modeling research based on advanced comp
utational methods will be conducted. In both phases, an outreach and
infrastructure component to create a Virtual Health Information
Resource will be created. It will serve as a core resource to advance
biomedical sciences research and education; promote collaborative
research; enable access to digital information via the Internet and
the WWW and provide computational modeling laboratory for
undergraduate and graduate students including those who will be
pursuing PhD studies.
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26.
|
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| 1998 | COMPUTER MODEL DVMT: CELLULAR &POPULATION AIDS EPIDEMIOLOGY: AFRICAN AMERICANS | 2G12RR003059-11 | |
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|---|
| Application ID: | 6282014 |
|---|
| Budget Period: | 10/01/1997 - 09/30/1998 |
|---|
| Project Period: | 06/01/1998 - 05/31/1999 |
|---|
| Award Notice Date: | |
|---|
| Funding Mechanism: | |
|---|
| Department/ Organization Type: | - |
|---|
| Administering Institutes or Centers: | NATIONAL CENTER FOR RESEARCH RESOURCES |
|---|
| Awardee Organization: | TUSKEGEE UNIVERSITY |
|---|
| Total Cost: | |
|---|
| Spending Categories: |
|
|---|
This project consists of three interrelated and complimentary
activities of biomedical computing infrastructure development,
research and outreach. The research component focuses on computer
based scientific experimentation currently referred to as
computational epidenuiology. The goal is to build on our existing
strength in the area of epidemiologic modeling and biomedical
information management systems. The research will emphasizes
integrative computational models for CD4+ lymphocyte populations and
HIV viral load interactions so as to examine the effect of
intervention (drug) therapies individually and/or in combinations.
The objectives are to: a) strengthen and expand the biomedical
computing infrastructure for research at Tuskegee University; b) carry
out research that combines theoretical and clinical HIV/CD4+ cell
population interactions and to use the computational models to
evaluate antiretroviral intervention strategies with a focus on
African Americans; and, c) provide outreach by creating a Virtual
Health Information Resource with a focus on the health of minorities,
relying on the Internet and the VAW as the primary- mode for
communication and information sharing. The project will proceed in
two phases. In Phase I (years 1-2), collaboration and database
development will be emphasized. Collaboration with the University of
Alabama Medical School, where extensive clinical H1V/Al1DS studies are
being carried out, Wlill provide access to clinical and molecular
laboratory data that will be used in the modeling research.. In Phase
H (years 2-5), epidemiologic modeling research based on advanced comp
utational methods will be conducted. In both phases, an outreach and
infrastructure component to create a Virtual Health Information
Resource will be created. It will serve as a core resource to advance
biomedical sciences research and education; promote collaborative
research; enable access to digital information via the Internet and
the WWW and provide computational modeling laboratory for
undergraduate and graduate students including those who will be
pursuing PhD studies.
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27.
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| 1997 | COMPUTER MODEL DVMT: CELLULAR &POPULATION AIDS EPIDEMIOLOGY: AFRICAN AMERICANS | 5G12RR003059-10 | |
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|---|
| Application ID: | 6252619 |
|---|
| Budget Period: | 10/01/1996 - 09/30/1997 |
|---|
| Project Period: | 07/07/1997 - 05/31/1998 |
|---|
| Award Notice Date: | |
|---|
| Funding Mechanism: | |
|---|
| Department/ Organization Type: | - |
|---|
| Administering Institutes or Centers: | NATIONAL CENTER FOR RESEARCH RESOURCES |
|---|
| Awardee Organization: | TUSKEGEE UNIVERSITY |
|---|
| Total Cost: | |
|---|
| Spending Categories: |
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28.
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| 1996 | COMPUTER MODEL DEVELOPMENT--AIDS EPIDEMIOLOGY | 5G12RR003059-09 | |
|
|---|
| Application ID: | 5224416 |
|---|
| Budget Period: | - |
|---|
| Project Period: | - |
|---|
| Award Notice Date: | |
|---|
| Funding Mechanism: | |
|---|
| Department/ Organization Type: | - |
|---|
| Administering Institutes or Centers: | NATIONAL CENTER FOR RESEARCH RESOURCES |
|---|
| Awardee Organization: | |
|---|
| Total Cost: | |
|---|
| Spending Categories: |
|
|---|
The Computer Modeling Unit is involved in Research and
Outreach (service and training). The focus of our research is to
examine the complex and diverse determinants of Acquired
Immunodeficiency Syndrome (AIDS), using epidemiologic
modeling methodologies that emphasize systems analysis. The
specific research or objectives are as follows: A.1. Research
objectives: a) to develop a systems dynamics model for
AIDS with a focus on the epidemiology of AIDS in African-
Americans, b) to develop a systems dynamics model for the
epidemiology of AIDS with a focus on AIDS in Africans to use
for comparative purposes with the model above, c) to develop
a systems dynamics model for CD4+ lymphocyte cellular
population dynamics in AIDS and in selected target cell population
dynamics in AIDS-like animal retroviruses, d)to develop an expert
systems/neural network model of AIDS with a focus on the
epidemiology of AIDS in African-Americans, e) to develop
methods to integrate or couple systems dynamics quantitative
modeling with quantitative (expert systems/neural networking)
modeling using AIDS in African-Americans as the test bed,
f) to utilize the computational models to study the comprehensive
epidemiology of AIDS form the level of cellular to that of human
populations. A.2. Outreach (service and training) objectives:
a) provide service to RCMI and other scientists in the School of
Veterinary Medicine (SVM) in the areas of epidemiology
(population health studies), statistical research design and data
analysis, information management, networking b) provide training
and workshops to faculty in the areas described above, provide
training to minority undergraduate and graduate students to
expose them to systematic and structured science studies so
as to increase the number of students who will be attracted to
such fields, c) develop and disseminate information on the
research being conducted under this RCMI project as well as
on computer based AIDS information systems.
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