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Flores-Otero, Jacqueline

One or more keywords matched the following properties of Flores-Otero, Jacqueline

Property	Value
overview	Interests: Our goal is to elucidate the role of adhesion G protein-coupled receptors (GPCRs) in regulating retinoblastoma (Rb) tumor development and progression with a focus on cellular migration. By using a combination of cellular and molecular approaches, in tandem with Total Internal Reflection Fluorescence (TIRF) microscopy, we will define the kinetic properties of these orphan receptors, and furthermore determine how alterations in the kinetics and signaling of adhesion proteins regulate Rb cell motility. Present Funding: NIH RCMI; Puerto Rico Science & Technology

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overview

Interests: Our goal is to elucidate the role of adhesion G protein-coupled receptors (GPCRs) in regulating retinoblastoma (Rb) tumor development and progression with a focus on cellular migration. By using a combination of cellular and molecular approaches, in tandem with Total Internal Reflection Fluorescence (TIRF) microscopy, we will define the kinetic properties of these orphan receptors, and furthermore determine how alterations in the kinetics and signaling of adhesion proteins regulate Rb cell motility. Present Funding: NIH RCMI; Puerto Rico Science & Technology

One or more keywords matched the following items that are connected to Flores-Otero, Jacqueline

Item Type	Name
Academic Article	Coexpression of normally incompatible developmental pathways in retinoblastoma genesis.
Academic Article	Targeting the p53 pathway in retinoblastoma with subconjunctival Nutlin-3a.
Academic Article	A novel retinoblastoma therapy from genomic and epigenetic analyses.
Academic Article	Targeting the Platelet-Derived Growth Factor-beta Stimulatory Circuitry to Control Retinoblastoma Seeds.
Concept	Retinoblastoma
Concept	Retinoblastoma Protein
Concept	Genes, Retinoblastoma
Academic Article	Adhesion G protein-coupled receptor, ELTD1, is a potential therapeutic target for retinoblastoma migration and invasion.

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Retinoblastoma

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