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My research has been focused in laser devices and biomedical-related optical physics and technology, such as photoacoustic imaging, microwave-induced thermoelastic imaging, imaging and focusing of light through optically diffusive media ( tissues, multimode fibers, etc.) . Recent research highlights are shown below.
High-resolution photoacoustic imaging of ocular tissues
Using focused laser beam to generate ultrasound with pinpoint precision, we have achieved 20-fold improvement in the resolution of photoacoustic images compared to conventional ultrasound images.
Potential applications of this technique include clinical examination of superficial and thin tissues containing optically absorbing pigments such as melanin or hemoglobin, including skin, mucosa, and ocular tissues (iris, retina and choroid).
Focusing through optically diffusive media
We have demonstrated that laser beam can be focused through diffusive media such as a ground glass or biological tissue onto a light absorber by shaping the wavefront.
Delivery of a focused laser beam through a multimode fiber
Multimode fibers are a closed system of diffuse reflectors. The interference among the fiber modes creates a random granular pattern, known as speckle, at the output and causes a total loss of spatial coherence. We have demonstrated that the coherence of the beam transmitted through multimode fibers can be restored by wavefront shaping. This can be done at the input or output ends. Potential applications include delivery of a focused laser beam through an endoscope for laser surgery.
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