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One or more keywords matched the following properties of Das, Salil
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overview I have broad background in biochemistry, molecular biology and environmental toxicology, with specific training and expertise in several research areas. My current research focuses on molecular mechanisms of lung injury/fibrosis, lung cancer and breast cancer. I have developed a guinea pig model of lung injury/fibrosis induced by direct and environmental smoke and mustard gas, a chemical warfare agent and currently investigating the potential role of an antioxidant liposome containing N-acetylcysteine and tocopherol as an antidote against lung injury/fibrosis. We have validated translocator protein as biomarker of breast cancer and established that dietary soy protein has a beneficial effect in delaying the development of breast cancer and controlling its aggressiveness. As PI on several NIH, DOD and FAMRI -funded research projects, I have trained a large number of postdoctoral (20), graduate (10), medical (24), dental (12), undergraduate (15) and high school students (8) in my laboratory. I have the expertise, leadership and enthusiasm necessary to participate in the summer research training of medical students as proposed in this project. I am member of Biochemical Society (London), American Institute of Biochemistry and Molecular Biology, Society of Sigma Xi, American Oil Chemists Society, Association of American Advancement of Sciences.
One or more keywords matched the following items that are connected to Das, Salil
Item TypeName
Grant Abnormality in Gene Expression of Key Mediators of Vitamin A Action in COPD
Academic Article Induction of neuronal damage in guinea pig brain by intratracheal infusion of 2-chloroethyl ethyl sulfide, a mustard gas analog.
Academic Article Antioxidant liposomes protect against CEES-induced lung injury by decreasing SAF-1/MAZ-mediated inflammation in the guinea pig lung.
Academic Article Uptake of all-trans retinoic acid-containing aerosol by inhalation to lungs in a guinea pig model system--a pilot study.
Academic Article Lung retinoid metabolism and signaling in chronic obstructive pulmonary disease.
Academic Article Effects of intratracheal exposure of 2-chloroethyl ethyl sulfide (CEES) on the activation of CCAAT-enhancer-binding protein (C/EBP) and its protection by antioxidant liposome.
Academic Article Toxic effects of fatty acid anilides on the oxygen defense systems of guinea pig lungs and erythrocytes.
Academic Article Mainstream and sidestream cigarette smoke exposure increases retinol in guinea pig lungs.
Academic Article Signal transduction events in lung injury induced by 2-chloroethyl ethyl sulfide, a mustard analog.
Academic Article Prophylactic protection by N-acetylcysteine against the pulmonary injury induced by 2-chloroethyl ethyl sulfide, a mustard analogue.
Academic Article Harmful health effects of cigarette smoking.
Academic Article Attenuation of half sulfur mustard gas-induced acute lung injury in rats.
Academic Article Inhibition of cholinephosphotransferase activity in lung injury induced by 2-chloroethyl ethyl sulfide, a mustard analog.
Academic Article Modulation of the expression of superoxide dismutase gene in lung injury by 2-chloroethyl ethyl sulfide, a mustard analog.
Academic Article Modulation of binding characteristics of peripheral benzodiazepine receptors in vitamin A-deficient guinea pig lung.
Academic Article Desensitization of beta-adrenergic receptors in lung injury induced by 2-chloroethyl ethyl sulfide, a mustard analog.
Academic Article Protection of half sulfur mustard gas-induced lung injury in guinea pigs by antioxidant liposomes.
Academic Article Role of MAPK/AP-1 signaling pathway in the protection of CEES-induced lung injury by antioxidant liposome.
Academic Article Activation of MAPK/AP-1 signaling pathway in lung injury induced by 2-chloroethyl ethyl sulfide, a mustard gas analog.
Concept Lung
Concept Lung Diseases
Concept Lung Neoplasms
Concept Lung Injury
Academic Article Study of properties of cholinephosphotransferase from fetal guinea pig lung mitochondria and microsomes.
Academic Article The differential effect of polymyxin B1 on guinea pig lung mitochondrial and microsomal glycerophosphate acyltransferase.
Academic Article Effect of vitamin A deficiency on pulmonary defense systems of guinea pig lung.
Academic Article Existence of cholinephosphotransferase in mitochondria and microsomes of liver and lung of guinea pig and rat.
Academic Article Gestational variation of glycerophosphate acyltransferase activity in maternal guinea pig lung and possible role of thyroid hormone in its de novo synthesis.
Academic Article Effects of centrophenoxine on cholinephosphotransferase activity in maternal and fetal guinea pig lung.
Academic Article Subcellular distribution of "peripheral type" binding sites for [3H]Ro5-4864 in guinea pig lung. Localization to the mitochondrial inner membrane.
Academic Article Development of pancellular toxicity in guinea pig lung by ingestion of oleylanilide.
Academic Article Role of thyroid hormone in de novo synthesis of cholinephosphotransferase in guinea pig lung mitochondria and microsomes.
Academic Article Effects of aging on cholinephosphotransferase activity on guinea pig lung mitochondria and microsomes.
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