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Stewart, LaMonica

One or more keywords matched the following properties of Stewart, LaMonica

Property	Value
overview	Dr. LaMonica Stewart is an Associate Professor in the Department of Biochemistry and Cancer Biology at Meharry Medical College. Since joining the Meharry faculty in 2004, Dr. Stewart has primarily performed research and been involved in the training of medical and Ph.D. graduate students. Her current research projects examine the regulation of prostate cancer growth and progression by compounds that activate the peroxisome proliferator activated receptor gamma (PPARg). Her laboratory uses human prostate cancer cell lines and xenograft mouse models to define the mechanisms by which PPARg agonists inhibit tumor cell proliferation and invasion. Her research has revealed that one class of PPAR agonists, the thiazolindinediones, regulates activation of the androgen receptor and alters expression of several proteins that control cell cycle progression. The data from these studies has also shown that the thiazolidinediones activate both PPAR dependent and PPAR-independent signaling pathways within human prostate cancer cells. The information gained from these studies will be used to identify new treatment strategies for early and late stage prostate cancer. Dr. Stewart is expanding her research program to include studies that examine the effect of PPARg ligands and anti-diabetic agents on other diseases of the prostate and urogenital system as well as the factors that control PPARg expression within the prostate. She also has begun to explore the effects of metformin and other antidiabetic agents on prostate cancer growth and progression. Dr. Stewart also serves as the Director of Graduate Studies for the Department of Biochemistry and Cancer Biology at Meharry. In this role, she advises students within the Biochemistry and Cancer Biology Ph.D. program and serves on multiple committees within the School of Graduate Studies and Research. Dr. Stewart is a 1991 magna cum laude graduate of Texas A&M University in College Station, TX, where she earned a B.S. in Biochemistry. She earned a Ph.D. in Pharmacology and Toxicology from the University of Texas Medical Branch in 1996. Following her doctoral training, Dr. Stewart completed postdoctoral fellowships at the National Cancer Institute in Bethesda, MD and Baylor College of Medicine.

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overview

Dr. LaMonica Stewart is an Associate Professor in the Department of Biochemistry and Cancer Biology at Meharry Medical College. Since joining the Meharry faculty in 2004, Dr. Stewart has primarily performed research and been involved in the training of medical and Ph.D. graduate students. Her current research projects examine the regulation of prostate cancer growth and progression by compounds that activate the peroxisome proliferator activated receptor gamma (PPARg). Her laboratory uses human prostate cancer cell lines and xenograft mouse models to define the mechanisms by which PPARg agonists inhibit tumor cell proliferation and invasion. Her research has revealed that one class of PPAR agonists, the thiazolindinediones, regulates activation of the androgen receptor and alters expression of several proteins that control cell cycle progression. The data from these studies has also shown that the thiazolidinediones activate both PPAR dependent and PPAR-independent signaling pathways within human prostate cancer cells. The information gained from these studies will be used to identify new treatment strategies for early and late stage prostate cancer. Dr. Stewart is expanding her research program to include studies that examine the effect of PPARg ligands and anti-diabetic agents on other diseases of the prostate and urogenital system as well as the factors that control PPARg expression within the prostate. She also has begun to explore the effects of metformin and other antidiabetic agents on prostate cancer growth and progression. Dr. Stewart also serves as the Director of Graduate Studies for the Department of Biochemistry and Cancer Biology at Meharry. In this role, she advises students within the Biochemistry and Cancer Biology Ph.D. program and serves on multiple committees within the School of Graduate Studies and Research. Dr. Stewart is a 1991 magna cum laude graduate of Texas A&M University in College Station, TX, where she earned a B.S. in Biochemistry. She earned a Ph.D. in Pharmacology and Toxicology from the University of Texas Medical Branch in 1996. Following her doctoral training, Dr. Stewart completed postdoctoral fellowships at the National Cancer Institute in Bethesda, MD and Baylor College of Medicine.

One or more keywords matched the following items that are connected to Stewart, LaMonica

Item Type	Name
Grant	VITAMIN D AND INHIBITION OF PROSTATE CANCER CELL GROWTH
Grant	Regulation of Prostate Cancer Growth by PPARg Ligands
Academic Article	The PPAR? ligand ciglitazone regulates androgen receptor activation differently in androgen-dependent versus androgen-independent human prostate cancer cells.
Academic Article	Troglitazone suppresses c-Myc levels in human prostate cancer cells via a PPAR?-independent mechanism.
Academic Article	The PPAR Gamma Agonist Troglitazone Regulates Erk 1/2 Phosphorylation via a PPAR?-Independent, MEK-Dependent Pathway in Human Prostate Cancer Cells.
Academic Article	The Androgen Receptor Regulates PPAR? Expression and Activity in Human Prostate Cancer Cells.
Academic Article	Crosstalk between the Androgen Receptor and PPAR Gamma Signaling Pathways in the Prostate.
Academic Article	p53 Is required for 1,25-dihydroxyvitamin D3-induced G0 arrest but is not required for G1 accumulation or apoptosis of LNCaP prostate cancer cells.
Academic Article	Vitamin D and prostate cancer.
Academic Article	Identification and characterization of a novel rat ov-serpin family member, trespin.
Academic Article	Regulation of trespin expression by modulators of cell growth, differentiation, and apoptosis in prostatic epithelial cells.
Academic Article	Inhibition of proliferation and induction of apoptosis by 25-hydroxyvitamin D3-3beta-(2)-Bromoacetate, a nontoxic and vitamin D receptor-alkylating analog of 25-hydroxyvitamin D3 in prostate cancer cells.
Academic Article	Role of insulin-like growth factor binding proteins in 1alpha,25-dihydroxyvitamin D(3)-induced growth inhibition of human prostate cancer cells.
Academic Article	Vitamin D receptor agonists induce prostatic acid phosphatase to reduce cell growth and HER-2 signaling in LNCaP-derived human prostate cancer cells.
Academic Article	Thiazolidinediones regulate expression of cell cycle proteins in human prostate cancer cells via PPARgamma-dependent and PPARgamma-independent pathways.
Concept	Prostate
Concept	Prostate-Specific Antigen
Academic Article	The role of transforming growth factor-beta1, -beta2, and -beta3 in androgen-responsive growth of NRP-152 rat prostatic epithelial cells.
Academic Article	Loss of responsiveness to transforming growth factor beta induces malignant transformation of nontumorigenic rat prostate epithelial cells.

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