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Ruan, Jianhua

One or more keywords matched the following properties of Ruan, Jianhua

Property	Value
overview	My research interests lie in the broad area of bioinformatics, computational systems biology, and data mining. More specifically, my current research is focused on the following three directions: (1) module discovery and analysis in complex networks, with applications in protein complex prediction and microarray data clustering; (2) modeling and analysis of transcriptional/post-transcriptional regulatory networks (e.g. DNA motif finding and ChIP-seq data analysis); and (3) network-based biomarker discovery and disease classification via integrated analysis of heterogonous functional genomics data such as gene expression, protein-protein interactions, and microRNA-mRNA interactions. My research has been sponsored by NIH, NSF, and the San Antonio Life Sciences Institute.

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Value

overview

My research interests lie in the broad area of bioinformatics, computational systems biology, and data mining. More specifically, my current research is focused on the following three directions: (1) module discovery and analysis in complex networks, with applications in protein complex prediction and microarray data clustering; (2) modeling and analysis of transcriptional/post-transcriptional regulatory networks (e.g. DNA motif finding and ChIP-seq data analysis); and (3) network-based biomarker discovery and disease classification via integrated analysis of heterogonous functional genomics data such as gene expression, protein-protein interactions, and microRNA-mRNA interactions. My research has been sponsored by NIH, NSF, and the San Antonio Life Sciences Institute.

One or more keywords matched the following items that are connected to Ruan, Jianhua

Item Type	Name
Academic Article	An ensemble learning approach to reverse-engineering transcriptional regulatory networks from time-series gene expression data.
Academic Article	A top-performing algorithm for the DREAM3 gene expression prediction challenge.
Academic Article	A systems biology approach to the identification and analysis of transcriptional regulatory networks in osteocytes.
Academic Article	A novel swarm intelligence algorithm for finding DNA motifs.
Academic Article	A genome-wide cis-regulatory element discovery method based on promoter sequences and gene co-expression networks.
Academic Article	Computational modeling of in vivo and in vitro protein-DNA interactions by multiple instance learning.
Academic Article	Logo2PWM: a tool to convert sequence logo to position weight matrix.
Academic Article	Comparative evaluation of network features for the prediction of breast cancer metastasis.
Concept	Computational Biology
Concept	Systems Biology
Academic Article	Variations in the transcriptome of Alzheimer's disease reveal molecular networks involved in cardiovascular diseases.
Academic Article	Building and analyzing protein interactome networks by cross-species comparisons.
Academic Article	Spatial mapping of single cells in the Drosophila embryo from transcriptomic data based on topological consistency.

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Biology