Item Type | Name |
Academic Article
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Down-regulation of aminolevulinate synthase, the rate-limiting enzyme for heme biosynthesis in Alzheimer's disease.
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Academic Article
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Heme-a, the heme prosthetic group of cytochrome c oxidase, is increased in Alzheimer's disease.
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Academic Article
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Variably protease-sensitive prionopathy: a new sporadic disease of the prion protein.
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Academic Article
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Upregulation of presenilin 1 in brains of sporadic, late-onset Alzheimer's disease.
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Academic Article
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The cell cycle regulator phosphorylated retinoblastoma protein is associated with tau pathology in several tauopathies.
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Academic Article
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Dissociated amyloid-beta antibody levels as a serum biomarker for the progression of Alzheimer's disease: a population-based study.
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Academic Article
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Evidence for the progression through S-phase in the ectopic cell cycle re-entry of neurons in Alzheimer disease.
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Academic Article
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Nanoparticle and iron chelators as a potential novel Alzheimer therapy.
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Academic Article
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Intraneuronal amyloid beta accumulation and oxidative damage to nucleic acids in Alzheimer disease.
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Academic Article
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Widespread distribution of reticulon-3 in various neurodegenerative diseases.
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Academic Article
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Indoleamine 2,3-dioxygenase and 3-hydroxykynurenine modifications are found in the neuropathology of Alzheimer's disease.
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Academic Article
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CD3 in Lewy pathology: does the abnormal recall of neurodevelopmental processes underlie Parkinson's disease.
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Academic Article
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Impaired mitochondrial biogenesis contributes to mitochondrial dysfunction in Alzheimer's disease.
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Academic Article
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Hydroxynonenal-generated crosslinking fluorophore accumulation in Alzheimer disease reveals a dichotomy of protein turnover.
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Academic Article
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Isotyping the human TOMM40 variable-length polymorphism by gene amplification and restriction digest.
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Academic Article
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Modification of amyloid-?1-42 fibril structure by methionine-35 oxidation.
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Academic Article
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A novel origin for granulovacuolar degeneration in aging and Alzheimer's disease: parallels to stress granules.
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Academic Article
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Mark A. Smith: neurocytochemistry innovator.
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Academic Article
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The earliest stage of cognitive impairment in transition from normal aging to Alzheimer disease is marked by prominent RNA oxidation in vulnerable neurons.
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Academic Article
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DNA damage in Alzheimer disease lymphocytes and its relation to premature centromere division.
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Academic Article
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Dysregulation of leptin signaling in Alzheimer disease: evidence for neuronal leptin resistance.
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Academic Article
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Proteolytic cleavage of polymeric tau protein by caspase-3: implications for Alzheimer disease.
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Academic Article
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A clinical study of lupron depot in the treatment of women with Alzheimer's disease: preservation of cognitive function in patients taking an acetylcholinesterase inhibitor and treated with high dose lupron over 48 weeks.
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Academic Article
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Antimicrobial peptide ?-defensin-1 expression is upregulated in Alzheimer's brain.
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Academic Article
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Accumulation of intraneuronal amyloid-? is common in normal brain.
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Academic Article
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Selenoprotein S Reduces Endoplasmic Reticulum Stress-Induced Phosphorylation of Tau: Potential Role in Selenate Mitigation of Tau Pathology.
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Academic Article
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Estrogen receptor-a is localized to neurofibrillary tangles in Alzheimer's disease.
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Academic Article
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Fibrillar Amyloid-? Accumulation Triggers an Inflammatory Mechanism Leading to Hyperphosphorylation of the Carboxyl-Terminal End of Tau Polypeptide in the Hippocampal Formation of the 3?Tg-AD Transgenic Mouse.
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Academic Article
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Putative Gonadotropin-Releasing Hormone Agonist Therapy and Dementia: An Application of Medicare Hospitalization Claims Data.
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Academic Article
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Diminished O-GlcNAcylation in Alzheimer's disease is strongly correlated with mitochondrial anomalies.
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Academic Article
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The sterol regulatory element-binding protein 2 is dysregulated by tau alterations in Alzheimer disease.
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Academic Article
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Rab10 Phosphorylation is a Prominent Pathological Feature in Alzheimer's Disease.
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Academic Article
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No Evidence of Increased Chronic Traumatic Encephalopathy Pathology or Neurodegenerative Proteinopathy in Former Military Service Members: A Preliminary Study.
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Academic Article
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Differences in structure and function between human and murine tau.
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Academic Article
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Neuroprotective and Antioxidant Effect of Ginkgo biloba Extract Against AD and Other Neurological Disorders.
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Academic Article
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Neuropathology in Consecutive Forensic Consultation Cases with a History of Remote Traumatic Brain Injury.
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Academic Article
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Decreased salivary lactoferrin levels are specific to Alzheimer's disease.
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Academic Article
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Hydroxynonenal adducts indicate a role for lipid peroxidation in neocortical and brainstem Lewy bodies in humans.
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Academic Article
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Neuronal RNA oxidation is a prominent feature of dementia with Lewy bodies.
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Academic Article
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Atherosclerotic lesions and mitochondria DNA deletions in brain microvessels as a central target for the development of human AD and AD-like pathology in aged transgenic mice.
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Academic Article
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Role of high mobility group protein-1 (HMG1) in amyloid-beta homeostasis.
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Academic Article
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Distribution, levels, and activation of MEK1 in Alzheimer's disease.
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Academic Article
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Mitochondria and vascular lesions as a central target for the development of Alzheimer's disease and Alzheimer disease-like pathology in transgenic mice.
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Academic Article
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Elevated expression of a regulator of the G2/M phase of the cell cycle, neuronal CIP-1-associated regulator of cyclin B, in Alzheimer's disease.
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Academic Article
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Neuronal RNA oxidation is a prominent feature of familial Alzheimer's disease.
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Academic Article
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Systemic increase of oxidative nucleic acid damage in Parkinson's disease and multiple system atrophy.
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Academic Article
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Oxidative damage to nucleic acids in human prion disease.
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Academic Article
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Elevated luteinizing hormone expression colocalizes with neurons vulnerable to Alzheimer's disease pathology.
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Academic Article
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Metal binding and oxidation of amyloid-beta within isolated senile plaque cores: Raman microscopic evidence.
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Academic Article
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JKK1, an upstream activator of JNK/SAPK, is activated in Alzheimer's disease.
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Academic Article
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Ectopic localization of phosphorylated histone H3 in Alzheimer's disease: a mitotic catastrophe?
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Academic Article
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Microtubule reduction in Alzheimer's disease and aging is independent of tau filament formation.
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Academic Article
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Possible involvement of Wiskott-Aldrich syndrome protein family in aberrant neuronal sprouting in Alzheimer's disease.
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Academic Article
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Increased p27, an essential component of cell cycle control, in Alzheimer's disease.
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Academic Article
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Oxidative damage in the olfactory system in Alzheimer's disease.
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Academic Article
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Aberrant expression of metabotropic glutamate receptor 2 in the vulnerable neurons of Alzheimer's disease.
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Academic Article
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Perspectives on the amyloid-beta cascade hypothesis.
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Academic Article
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Neuroprotective properties of Bcl-w in Alzheimer disease.
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Academic Article
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Mitochondrial failures in Alzheimer's disease.
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Academic Article
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Mitogen- and stress-activated protein kinase 1: convergence of the ERK and p38 pathways in Alzheimer's disease.
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Academic Article
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Nanoparticle iron chelators: a new therapeutic approach in Alzheimer disease and other neurologic disorders associated with trace metal imbalance.
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Academic Article
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Ectopic expression of phospho-Smad2 in Alzheimer's disease: uncoupling of the transforming growth factor-beta pathway?
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Academic Article
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Overexpression of GRK2 in Alzheimer disease and in a chronic hypoperfusion rat model is an early marker of brain mitochondrial lesions.
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Academic Article
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Alzheimer-specific epitopes of tau represent lipid peroxidation-induced conformations.
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Academic Article
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Effect of quinones on microtubule polymerization: a link between oxidative stress and cytoskeletal alterations in Alzheimer's disease.
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Academic Article
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Estrogen bows to a new master: the role of gonadotropins in Alzheimer pathogenesis.
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Academic Article
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Redox metals and oxidative abnormalities in human prion diseases.
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Academic Article
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Chitin-like polysaccharides in Alzheimer's disease brains.
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Academic Article
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The (un)balance between metabolic and oxidative abnormalities and cellular compensatory responses in Alzheimer disease.
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Academic Article
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Increased expression of p130 in Alzheimer disease.
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Academic Article
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Aberrant localization of importin alpha1 in hippocampal neurons in Alzheimer disease.
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Academic Article
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Increased expression of the remodeling- and tumorigenic-associated factor osteopontin in pyramidal neurons of the Alzheimer's disease brain.
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Academic Article
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Indices of metabolic dysfunction and oxidative stress.
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Academic Article
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Cerebrotendinous xanthomatosis: case report with evidence of oxidative stress.
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Academic Article
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Redox active iron accumulation in aceruloplasminemia.
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Academic Article
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Leucine-rich repeat kinase 2 colocalizes with alpha-synuclein in Parkinson's disease, but not tau-containing deposits in tauopathies.
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Academic Article
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Cleavage and conformational changes of tau protein follow phosphorylation during Alzheimer's disease.
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Academic Article
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Antigen-antibody dissociation in Alzheimer disease: a novel approach to diagnosis.
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Academic Article
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Three-dimensional tomographic imaging and characterization of iron compounds within Alzheimer's plaque core material.
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Academic Article
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Tau--an inhibitor of deacetylase HDAC6 function.
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Academic Article
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Impaired balance of mitochondrial fission and fusion in Alzheimer's disease.
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Academic Article
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BRCA1 may modulate neuronal cell cycle re-entry in Alzheimer disease.
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Academic Article
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Autophagocytosis of mitochondria is prominent in Alzheimer disease.
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Academic Article
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Neuronal mitochondrial amelioration by feeding acetyl-L-carnitine and lipoic acid to aged rats.
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Concept
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Aged
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Concept
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Aged, 80 and over
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Concept
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Middle Aged
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Academic Article
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What is aging? What is its role in Alzheimer's disease? What can we do about it?
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Academic Article
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Alterations of the X Chromosome in Lymphocytes of Alzheimer's Disease Patients.
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Academic Article
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PARK2 enhancement is able to compensate mitophagy alterations found in sporadic Alzheimer's disease.
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Academic Article
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Slower Dynamics and Aged Mitochondria in Sporadic Alzheimer's Disease.
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Academic Article
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Analysis of the Relationship Between Metalloprotease-9 and Tau Protein in Alzheimer's Disease.
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Academic Article
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Low plasma leptin in cognitively impaired ADNI subjects: gender differences and diagnostic and therapeutic potential.
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Academic Article
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Serial reconstruction of beta-protein amyloid plaques: relationship to microvessels and size distribution.
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Academic Article
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Filaments of Lewy bodies contain insoluble cytoskeletal elements.
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Academic Article
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Alpha 1-antitrypsin and alpha 1-antichymotrypsin are in the lesions of Alzheimer's disease.
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Academic Article
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Basic fibroblast growth factor binds to filamentous inclusions of neurodegenerative diseases.
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Academic Article
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Senile plaque neurites in Alzheimer disease accumulate amyloid precursor protein.
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Academic Article
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Tropomyosin isoform expression in normal and neoplastic astrocytes.
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Academic Article
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Age-dependent pattern of intermediate filament protein expression in the human pineal gland.
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Academic Article
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Antigenic profile of plaques and neurofibrillary tangles in the amygdala in Down's syndrome: a comparison with Alzheimer's disease.
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Academic Article
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Association of heparan sulfate proteoglycan with the neurofibrillary tangles of Alzheimer's disease.
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Academic Article
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Tropomyosin distinguishes Lewy bodies of Parkinson disease from other neurofibrillary pathology.
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Academic Article
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Neuronal and microglial involvement in beta-amyloid protein deposition in Alzheimer's disease.
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Academic Article
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Immunochemical demonstration of tropomyosin in the neurofibrillary pathology of Alzheimer's disease.
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Academic Article
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Electron microscopic localization of Alzheimer neurofibrillary tangle components recognized by an antiserum to paired helical filaments.
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Academic Article
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Coexistence of cytokeratin, vimentin and neurofilament protein in human choroid plexus. An immunohistochemical study of intermediate filaments in neuroepithelial tissues.
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Academic Article
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Phosphorylation of neurofilaments is altered in amyotrophic lateral sclerosis.
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Academic Article
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Tau-reactive neurofibrillary tangles in cerebellar cortex from patients with Alzheimer's disease.
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Academic Article
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The glucose transporter of the human brain and blood-brain barrier.
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Academic Article
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Influence of neuronal location on antigenic properties of neurofibrillary tangles.
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Academic Article
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Paired helical filaments from Alzheimer disease patients contain cytoskeletal components.
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Academic Article
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Acetylcholinesterase and its association with heparan sulphate proteoglycans in cortical amyloid deposits of Alzheimer's disease.
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Academic Article
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Cytokeratin expression in human spinal meninges and ependymal cells.
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Academic Article
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Beta protein immunoreactivity is found in the majority of neurofibrillary tangles of Alzheimer's disease.
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Academic Article
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Dystrophic neurites infiltrate extracellular neurofibrillary tangles in Alzheimer disease.
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Academic Article
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Microglia are associated with the extracellular neurofibrillary tangles of Alzheimer disease.
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Academic Article
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Basic fibroblast growth factor binding is a marker for extracellular neurofibrillary tangles in Alzheimer disease.
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Academic Article
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Widespread serum amyloid P immunoreactivity in cortical amyloid deposits and the neurofibrillary pathology of Alzheimer's disease and other degenerative disorders.
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Academic Article
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Abnormal tau-reactive filaments in olfactory mucosa in biopsy specimens of patients with probable Alzheimer's disease.
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Academic Article
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Neuropil threads of Alzheimer's disease show a marked alteration of the normal cytoskeleton.
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Academic Article
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The presence of tau distinguishes Lewy bodies of diffuse Lewy body disease from those of idiopathic Parkinson disease.
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Academic Article
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The widespread alteration of neurites in Alzheimer's disease may be unrelated to amyloid deposition.
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Academic Article
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Ubiquitin is detected in neurofibrillary tangles and senile plaque neurites of Alzheimer disease brains.
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Academic Article
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Alz 50 recognizes abnormal filaments in Alzheimer's disease and progressive supranuclear palsy.
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Academic Article
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Antibodies to the neuronal cytoskeleton are elicited by Alzheimer paired helical filament fractions.
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Academic Article
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Dystrophic neurites define diffuse as well as core-containing senile plaques in Alzheimer's disease.
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Academic Article
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Extracellular neurofibrillary tangles reflect neuronal loss and provide further evidence of extensive protein cross-linking in Alzheimer disease.
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Academic Article
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Immunochemical identification of ubiquitin and heat-shock proteins in corpora amylacea from normal aged and Alzheimer's disease brains.
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Academic Article
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Degeneration of vascular muscle cells in cerebral amyloid angiopathy of Alzheimer disease.
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Academic Article
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Alpha 1-trypsin immunoreactivity in Alzheimer disease.
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Academic Article
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Alterations of low molecular weight acid phosphatase protein level in Alzheimer's disease.
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Academic Article
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Plasma membrane fragility in dystrophic neurites in senile plaques of Alzheimer's disease: an index of oxidative stress.
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Academic Article
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Filament heterogeneity within the dystrophic neurites of senile plaques suggests blockage of fast axonal transport in Alzheimer's disease.
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Academic Article
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Widespread peroxynitrite-mediated damage in Alzheimer's disease.
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Academic Article
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Iron accumulation in Alzheimer disease is a source of redox-generated free radicals.
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Academic Article
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Immunocytochemical evidence that the beta-protein precursor is an integral component of neurofibrillary tangles of Alzheimer's disease.
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Academic Article
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Amyloid P component and other acute-phase proteins associated with cerebellar A beta-deposits in Alzheimer's disease.
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Academic Article
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Induction of heme oxygenase-1 mRNA and protein in neocortex and cerebral vessels in Alzheimer's disease.
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Academic Article
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Characterization of the association of phospholipase C-delta with Alzheimer neurofibrillary tangles.
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Academic Article
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Alteration of phospholipase C-delta protein level and specific activity in Alzheimer's disease.
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Academic Article
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Chondroitin sulfate proteoglycans are a common component of neuronal inclusions and astrocytic reaction in neurodegenerative diseases.
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Academic Article
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Heme oxygenase-1 is associated with the neurofibrillary pathology of Alzheimer's disease.
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Academic Article
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Abnormal accumulation of phospholipase C-delta in filamentous inclusions of human neurodegenerative diseases.
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Academic Article
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Chondroitin sulfate proteoglycans are associated with the lesions of Alzheimer's disease.
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Academic Article
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Serine protease inhibitor antithrombin III and its messenger RNA in the pathogenesis of Alzheimer's disease.
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Academic Article
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Rimmed vacuoles of inclusion body myositis and oculopharyngeal muscular dystrophy contain amyloid precursor protein and lysosomal markers.
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Academic Article
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Oxidative damage in Alzheimer's.
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Academic Article
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Quantitative solubilization and analysis of insoluble paired helical filaments from Alzheimer disease.
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Academic Article
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Glycoxidation and oxidative stress in Parkinson disease and diffuse Lewy body disease.
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Academic Article
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4-Hydroxynonenal-derived advanced lipid peroxidation end products are increased in Alzheimer's disease.
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Academic Article
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Levuglandin E2-protein adducts in human plasma and vasculature.
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Academic Article
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Abnormal localization of iron regulatory protein in Alzheimer's disease.
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Academic Article
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Cerebrovascular muscle atrophy is a feature of Alzheimer's disease.
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Academic Article
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Cytochemical demonstration of oxidative damage in Alzheimer disease by immunochemical enhancement of the carbonyl reaction with 2,4-dinitrophenylhydrazine.
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Academic Article
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Altered glycosylation pattern of proteins in Alzheimer disease.
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Academic Article
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Striation is the characteristic neuritic abnormality in Alzheimer disease.
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Academic Article
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Dimethylargininase, a nitric oxide regulatory protein, in Alzheimer disease.
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Academic Article
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CI-ATPase and Na+/K(+)-ATPase activities in Alzheimer's disease brains.
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Academic Article
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Parkinson's disease is associated with oxidative damage to cytoplasmic DNA and RNA in substantia nigra neurons.
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Academic Article
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Increased neuronal glucose-6-phosphate dehydrogenase and sulfhydryl levels indicate reductive compensation to oxidative stress in Alzheimer disease.
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Academic Article
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Quinone reductase (NQO1), a sensitive redox indicator, is increased in Alzheimer's disease.
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Academic Article
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In Alzheimer's disease, heme oxygenase is coincident with Alz50, an epitope of tau induced by 4-hydroxy-2-nonenal modification.
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Academic Article
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Sequestration of iron by Lewy bodies in Parkinson's disease.
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Academic Article
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Activation and redistribution of c-jun N-terminal kinase/stress activated protein kinase in degenerating neurons in Alzheimer's disease.
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Academic Article
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Protein disulfide isomerase in Alzheimer disease.
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Academic Article
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Evidence for a novel heme-binding protein, HasAh, in Alzheimer disease.
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Academic Article
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Active glycation in neurofibrillary pathology of Alzheimer disease: N(epsilon)-(carboxymethyl) lysine and hexitol-lysine.
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Academic Article
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Alteration of proteins regulating apoptosis, Bcl-2, Bcl-x, Bax, Bak, Bad, ICH-1 and CPP32, in Alzheimer's disease.
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Academic Article
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What are the facts and artifacts of the pathogenesis and etiology of Alzheimer disease?
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Academic Article
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RNA oxidation is a prominent feature of vulnerable neurons in Alzheimer's disease.
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Academic Article
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Genetic evidence for oxidative stress in Alzheimer's disease.
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Academic Article
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Is increased redox-active iron in Alzheimer disease a failure of the copper-binding protein ceruloplasmin?
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Academic Article
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Activation of neuronal extracellular receptor kinase (ERK) in Alzheimer disease links oxidative stress to abnormal phosphorylation.
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Academic Article
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In situ oxidative catalysis by neurofibrillary tangles and senile plaques in Alzheimer's disease: a central role for bound transition metals.
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Academic Article
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Neuronal RNA oxidation in Alzheimer's disease and Down's syndrome.
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Academic Article
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Evidence that the beta-amyloid plaques of Alzheimer's disease represent the redox-silencing and entombment of abeta by zinc.
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Academic Article
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Activation of NADPH oxidase in Alzheimer's disease brains.
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Academic Article
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Lipoperoxidation is selectively involved in progressive supranuclear palsy.
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Academic Article
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Activation of p38 kinase links tau phosphorylation, oxidative stress, and cell cycle-related events in Alzheimer disease.
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Academic Article
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Neuronal oxidative stress precedes amyloid-beta deposition in Down syndrome.
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Academic Article
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Erythrocyte, plasma, and serum antioxidant activities in untreated toxic multinodular goiter patients.
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Academic Article
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Mitochondrial abnormalities in Alzheimer's disease.
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Academic Article
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Abortive apoptosis in Alzheimer's disease.
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Academic Article
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Differential activation of neuronal ERK, JNK/SAPK and p38 in Alzheimer disease: the 'two hit' hypothesis.
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Academic Article
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Activation of MKK6, an upstream activator of p38, in Alzheimer's disease.
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Academic Article
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Diabetes-associated sustained activation of the transcription factor nuclear factor-kappaB.
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Academic Article
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Increase of cdk5 is related to neurofibrillary pathology in progressive supranuclear palsy.
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Academic Article
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The mitochondrial common deletion in Parkinson's disease and related movement disorders.
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Academic Article
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Oxidative stress and predominant Abeta42(43) deposition in myopathies with rimmed vacuoles.
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Academic Article
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Oxidative damage is the earliest event in Alzheimer disease.
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Academic Article
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Increased expression of NOS and ET-1 immunoreactivity in human colorectal metastatic liver tumours is associated with selective depression of constitutive NOS immunoreactivity in vessel endothelium.
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Academic Article
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Reactive oxygen: its sources and significance in Alzheimer disease.
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Academic Article
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Conformational changes and cleavage of tau in Pick bodies parallel the early processing of tau found in Alzheimer pathology.
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Academic Article
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Neuronal binucleation in Alzheimer disease hippocampus.
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Academic Article
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Phosphorylation of tau protein at sites Ser(396-404) is one of the earliest events in Alzheimer's disease and Down syndrome.
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Academic Article
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Ra?l Mena: 1953-2014.
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Academic Article
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Dysfunctional tubular endoplasmic reticulum constitutes a pathological feature of Alzheimer's disease.
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Academic Article
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Phospho-Tau Protein Expression in the Cell Cycle of SH-SY5Y Neuroblastoma Cells: A Morphological Study.
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Grant
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NEUROFIBRILLARY PATHOLOGY IN ALZHEIMER DISEASE
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Academic Article
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Strawberry (Fragaria ananassa duch.) Alba extract attenuates DNA damage in lymphocytes of patients with Alzheimer's disease.
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Academic Article
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Corrigendum to "Slower Dynamics and Aged Mitochondria in Sporadic Alzheimer's Disease".
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Academic Article
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Lessons from antiamyloid-? immunotherapies in Alzheimer's disease.
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Academic Article
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Alzheimer's Disease: Not Just for the Aged?
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Academic Article
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Evaluation of N- and O-Linked Indole Triazines for a Dual Effect on a-Synuclein and Tau Aggregation.
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