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Item TypeName
Academic Article Down-regulation of aminolevulinate synthase, the rate-limiting enzyme for heme biosynthesis in Alzheimer's disease.
Academic Article Heme-a, the heme prosthetic group of cytochrome c oxidase, is increased in Alzheimer's disease.
Academic Article Variably protease-sensitive prionopathy: a new sporadic disease of the prion protein.
Academic Article Upregulation of presenilin 1 in brains of sporadic, late-onset Alzheimer's disease.
Academic Article The cell cycle regulator phosphorylated retinoblastoma protein is associated with tau pathology in several tauopathies.
Academic Article Dissociated amyloid-beta antibody levels as a serum biomarker for the progression of Alzheimer's disease: a population-based study.
Academic Article Evidence for the progression through S-phase in the ectopic cell cycle re-entry of neurons in Alzheimer disease.
Academic Article Nanoparticle and iron chelators as a potential novel Alzheimer therapy.
Academic Article Intraneuronal amyloid beta accumulation and oxidative damage to nucleic acids in Alzheimer disease.
Academic Article Widespread distribution of reticulon-3 in various neurodegenerative diseases.
Academic Article Indoleamine 2,3-dioxygenase and 3-hydroxykynurenine modifications are found in the neuropathology of Alzheimer's disease.
Academic Article CD3 in Lewy pathology: does the abnormal recall of neurodevelopmental processes underlie Parkinson's disease.
Academic Article Impaired mitochondrial biogenesis contributes to mitochondrial dysfunction in Alzheimer's disease.
Academic Article Hydroxynonenal-generated crosslinking fluorophore accumulation in Alzheimer disease reveals a dichotomy of protein turnover.
Academic Article Isotyping the human TOMM40 variable-length polymorphism by gene amplification and restriction digest.
Academic Article Modification of amyloid-?1-42 fibril structure by methionine-35 oxidation.
Academic Article A novel origin for granulovacuolar degeneration in aging and Alzheimer's disease: parallels to stress granules.
Academic Article Mark A. Smith: neurocytochemistry innovator.
Academic Article The earliest stage of cognitive impairment in transition from normal aging to Alzheimer disease is marked by prominent RNA oxidation in vulnerable neurons.
Academic Article DNA damage in Alzheimer disease lymphocytes and its relation to premature centromere division.
Academic Article Dysregulation of leptin signaling in Alzheimer disease: evidence for neuronal leptin resistance.
Academic Article Proteolytic cleavage of polymeric tau protein by caspase-3: implications for Alzheimer disease.
Academic Article A clinical study of lupron depot in the treatment of women with Alzheimer's disease: preservation of cognitive function in patients taking an acetylcholinesterase inhibitor and treated with high dose lupron over 48 weeks.
Academic Article Antimicrobial peptide ?-defensin-1 expression is upregulated in Alzheimer's brain.
Academic Article Accumulation of intraneuronal amyloid-? is common in normal brain.
Academic Article Selenoprotein S Reduces Endoplasmic Reticulum Stress-Induced Phosphorylation of Tau: Potential Role in Selenate Mitigation of Tau Pathology.
Academic Article Estrogen receptor-a is localized to neurofibrillary tangles in Alzheimer's disease.
Academic Article Fibrillar Amyloid-? Accumulation Triggers an Inflammatory Mechanism Leading to Hyperphosphorylation of the Carboxyl-Terminal End of Tau Polypeptide in the Hippocampal Formation of the 3?Tg-AD Transgenic Mouse.
Academic Article Putative Gonadotropin-Releasing Hormone Agonist Therapy and Dementia: An Application of Medicare Hospitalization Claims Data.
Academic Article Diminished O-GlcNAcylation in Alzheimer's disease is strongly correlated with mitochondrial anomalies.
Academic Article The sterol regulatory element-binding protein 2 is dysregulated by tau alterations in Alzheimer disease.
Academic Article Rab10 Phosphorylation is a Prominent Pathological Feature in Alzheimer's Disease.
Academic Article No Evidence of Increased Chronic Traumatic Encephalopathy Pathology or Neurodegenerative Proteinopathy in Former Military Service Members: A Preliminary Study.
Academic Article Differences in structure and function between human and murine tau.
Academic Article Neuroprotective and Antioxidant Effect of Ginkgo biloba Extract Against AD and Other Neurological Disorders.
Academic Article Neuropathology in Consecutive Forensic Consultation Cases with a History of Remote Traumatic Brain Injury.
Academic Article Decreased salivary lactoferrin levels are specific to Alzheimer's disease.
Academic Article Hydroxynonenal adducts indicate a role for lipid peroxidation in neocortical and brainstem Lewy bodies in humans.
Academic Article Neuronal RNA oxidation is a prominent feature of dementia with Lewy bodies.
Academic Article Atherosclerotic lesions and mitochondria DNA deletions in brain microvessels as a central target for the development of human AD and AD-like pathology in aged transgenic mice.
Academic Article Role of high mobility group protein-1 (HMG1) in amyloid-beta homeostasis.
Academic Article Distribution, levels, and activation of MEK1 in Alzheimer's disease.
Academic Article Mitochondria and vascular lesions as a central target for the development of Alzheimer's disease and Alzheimer disease-like pathology in transgenic mice.
Academic Article Elevated expression of a regulator of the G2/M phase of the cell cycle, neuronal CIP-1-associated regulator of cyclin B, in Alzheimer's disease.
Academic Article Neuronal RNA oxidation is a prominent feature of familial Alzheimer's disease.
Academic Article Systemic increase of oxidative nucleic acid damage in Parkinson's disease and multiple system atrophy.
Academic Article Oxidative damage to nucleic acids in human prion disease.
Academic Article Elevated luteinizing hormone expression colocalizes with neurons vulnerable to Alzheimer's disease pathology.
Academic Article Metal binding and oxidation of amyloid-beta within isolated senile plaque cores: Raman microscopic evidence.
Academic Article JKK1, an upstream activator of JNK/SAPK, is activated in Alzheimer's disease.
Academic Article Ectopic localization of phosphorylated histone H3 in Alzheimer's disease: a mitotic catastrophe?
Academic Article Microtubule reduction in Alzheimer's disease and aging is independent of tau filament formation.
Academic Article Possible involvement of Wiskott-Aldrich syndrome protein family in aberrant neuronal sprouting in Alzheimer's disease.
Academic Article Increased p27, an essential component of cell cycle control, in Alzheimer's disease.
Academic Article Oxidative damage in the olfactory system in Alzheimer's disease.
Academic Article Aberrant expression of metabotropic glutamate receptor 2 in the vulnerable neurons of Alzheimer's disease.
Academic Article Perspectives on the amyloid-beta cascade hypothesis.
Academic Article Neuroprotective properties of Bcl-w in Alzheimer disease.
Academic Article Mitochondrial failures in Alzheimer's disease.
Academic Article Mitogen- and stress-activated protein kinase 1: convergence of the ERK and p38 pathways in Alzheimer's disease.
Academic Article Nanoparticle iron chelators: a new therapeutic approach in Alzheimer disease and other neurologic disorders associated with trace metal imbalance.
Academic Article Ectopic expression of phospho-Smad2 in Alzheimer's disease: uncoupling of the transforming growth factor-beta pathway?
Academic Article Overexpression of GRK2 in Alzheimer disease and in a chronic hypoperfusion rat model is an early marker of brain mitochondrial lesions.
Academic Article Alzheimer-specific epitopes of tau represent lipid peroxidation-induced conformations.
Academic Article Effect of quinones on microtubule polymerization: a link between oxidative stress and cytoskeletal alterations in Alzheimer's disease.
Academic Article Estrogen bows to a new master: the role of gonadotropins in Alzheimer pathogenesis.
Academic Article Redox metals and oxidative abnormalities in human prion diseases.
Academic Article Chitin-like polysaccharides in Alzheimer's disease brains.
Academic Article The (un)balance between metabolic and oxidative abnormalities and cellular compensatory responses in Alzheimer disease.
Academic Article Increased expression of p130 in Alzheimer disease.
Academic Article Aberrant localization of importin alpha1 in hippocampal neurons in Alzheimer disease.
Academic Article Increased expression of the remodeling- and tumorigenic-associated factor osteopontin in pyramidal neurons of the Alzheimer's disease brain.
Academic Article Indices of metabolic dysfunction and oxidative stress.
Academic Article Cerebrotendinous xanthomatosis: case report with evidence of oxidative stress.
Academic Article Redox active iron accumulation in aceruloplasminemia.
Academic Article Leucine-rich repeat kinase 2 colocalizes with alpha-synuclein in Parkinson's disease, but not tau-containing deposits in tauopathies.
Academic Article Cleavage and conformational changes of tau protein follow phosphorylation during Alzheimer's disease.
Academic Article Antigen-antibody dissociation in Alzheimer disease: a novel approach to diagnosis.
Academic Article Three-dimensional tomographic imaging and characterization of iron compounds within Alzheimer's plaque core material.
Academic Article Tau--an inhibitor of deacetylase HDAC6 function.
Academic Article Impaired balance of mitochondrial fission and fusion in Alzheimer's disease.
Academic Article BRCA1 may modulate neuronal cell cycle re-entry in Alzheimer disease.
Academic Article Autophagocytosis of mitochondria is prominent in Alzheimer disease.
Academic Article Neuronal mitochondrial amelioration by feeding acetyl-L-carnitine and lipoic acid to aged rats.
Concept Aged
Concept Aged, 80 and over
Concept Middle Aged
Academic Article What is aging? What is its role in Alzheimer's disease? What can we do about it?
Academic Article Alterations of the X Chromosome in Lymphocytes of Alzheimer's Disease Patients.
Academic Article PARK2 enhancement is able to compensate mitophagy alterations found in sporadic Alzheimer's disease.
Academic Article Slower Dynamics and Aged Mitochondria in Sporadic Alzheimer's Disease.
Academic Article Analysis of the Relationship Between Metalloprotease-9 and Tau Protein in Alzheimer's Disease.
Academic Article Low plasma leptin in cognitively impaired ADNI subjects: gender differences and diagnostic and therapeutic potential.
Academic Article Serial reconstruction of beta-protein amyloid plaques: relationship to microvessels and size distribution.
Academic Article Filaments of Lewy bodies contain insoluble cytoskeletal elements.
Academic Article Alpha 1-antitrypsin and alpha 1-antichymotrypsin are in the lesions of Alzheimer's disease.
Academic Article Basic fibroblast growth factor binds to filamentous inclusions of neurodegenerative diseases.
Academic Article Senile plaque neurites in Alzheimer disease accumulate amyloid precursor protein.
Academic Article Tropomyosin isoform expression in normal and neoplastic astrocytes.
Academic Article Age-dependent pattern of intermediate filament protein expression in the human pineal gland.
Academic Article Antigenic profile of plaques and neurofibrillary tangles in the amygdala in Down's syndrome: a comparison with Alzheimer's disease.
Academic Article Association of heparan sulfate proteoglycan with the neurofibrillary tangles of Alzheimer's disease.
Academic Article Tropomyosin distinguishes Lewy bodies of Parkinson disease from other neurofibrillary pathology.
Academic Article Neuronal and microglial involvement in beta-amyloid protein deposition in Alzheimer's disease.
Academic Article Immunochemical demonstration of tropomyosin in the neurofibrillary pathology of Alzheimer's disease.
Academic Article Electron microscopic localization of Alzheimer neurofibrillary tangle components recognized by an antiserum to paired helical filaments.
Academic Article Coexistence of cytokeratin, vimentin and neurofilament protein in human choroid plexus. An immunohistochemical study of intermediate filaments in neuroepithelial tissues.
Academic Article Phosphorylation of neurofilaments is altered in amyotrophic lateral sclerosis.
Academic Article Tau-reactive neurofibrillary tangles in cerebellar cortex from patients with Alzheimer's disease.
Academic Article The glucose transporter of the human brain and blood-brain barrier.
Academic Article Influence of neuronal location on antigenic properties of neurofibrillary tangles.
Academic Article Paired helical filaments from Alzheimer disease patients contain cytoskeletal components.
Academic Article Acetylcholinesterase and its association with heparan sulphate proteoglycans in cortical amyloid deposits of Alzheimer's disease.
Academic Article Cytokeratin expression in human spinal meninges and ependymal cells.
Academic Article Beta protein immunoreactivity is found in the majority of neurofibrillary tangles of Alzheimer's disease.
Academic Article Dystrophic neurites infiltrate extracellular neurofibrillary tangles in Alzheimer disease.
Academic Article Microglia are associated with the extracellular neurofibrillary tangles of Alzheimer disease.
Academic Article Basic fibroblast growth factor binding is a marker for extracellular neurofibrillary tangles in Alzheimer disease.
Academic Article Widespread serum amyloid P immunoreactivity in cortical amyloid deposits and the neurofibrillary pathology of Alzheimer's disease and other degenerative disorders.
Academic Article Abnormal tau-reactive filaments in olfactory mucosa in biopsy specimens of patients with probable Alzheimer's disease.
Academic Article Neuropil threads of Alzheimer's disease show a marked alteration of the normal cytoskeleton.
Academic Article The presence of tau distinguishes Lewy bodies of diffuse Lewy body disease from those of idiopathic Parkinson disease.
Academic Article The widespread alteration of neurites in Alzheimer's disease may be unrelated to amyloid deposition.
Academic Article Ubiquitin is detected in neurofibrillary tangles and senile plaque neurites of Alzheimer disease brains.
Academic Article Alz 50 recognizes abnormal filaments in Alzheimer's disease and progressive supranuclear palsy.
Academic Article Antibodies to the neuronal cytoskeleton are elicited by Alzheimer paired helical filament fractions.
Academic Article Dystrophic neurites define diffuse as well as core-containing senile plaques in Alzheimer's disease.
Academic Article Extracellular neurofibrillary tangles reflect neuronal loss and provide further evidence of extensive protein cross-linking in Alzheimer disease.
Academic Article Immunochemical identification of ubiquitin and heat-shock proteins in corpora amylacea from normal aged and Alzheimer's disease brains.
Academic Article Degeneration of vascular muscle cells in cerebral amyloid angiopathy of Alzheimer disease.
Academic Article Alpha 1-trypsin immunoreactivity in Alzheimer disease.
Academic Article Alterations of low molecular weight acid phosphatase protein level in Alzheimer's disease.
Academic Article Plasma membrane fragility in dystrophic neurites in senile plaques of Alzheimer's disease: an index of oxidative stress.
Academic Article Filament heterogeneity within the dystrophic neurites of senile plaques suggests blockage of fast axonal transport in Alzheimer's disease.
Academic Article Widespread peroxynitrite-mediated damage in Alzheimer's disease.
Academic Article Iron accumulation in Alzheimer disease is a source of redox-generated free radicals.
Academic Article Immunocytochemical evidence that the beta-protein precursor is an integral component of neurofibrillary tangles of Alzheimer's disease.
Academic Article Amyloid P component and other acute-phase proteins associated with cerebellar A beta-deposits in Alzheimer's disease.
Academic Article Induction of heme oxygenase-1 mRNA and protein in neocortex and cerebral vessels in Alzheimer's disease.
Academic Article Characterization of the association of phospholipase C-delta with Alzheimer neurofibrillary tangles.
Academic Article Alteration of phospholipase C-delta protein level and specific activity in Alzheimer's disease.
Academic Article Chondroitin sulfate proteoglycans are a common component of neuronal inclusions and astrocytic reaction in neurodegenerative diseases.
Academic Article Heme oxygenase-1 is associated with the neurofibrillary pathology of Alzheimer's disease.
Academic Article Abnormal accumulation of phospholipase C-delta in filamentous inclusions of human neurodegenerative diseases.
Academic Article Chondroitin sulfate proteoglycans are associated with the lesions of Alzheimer's disease.
Academic Article Serine protease inhibitor antithrombin III and its messenger RNA in the pathogenesis of Alzheimer's disease.
Academic Article Rimmed vacuoles of inclusion body myositis and oculopharyngeal muscular dystrophy contain amyloid precursor protein and lysosomal markers.
Academic Article Oxidative damage in Alzheimer's.
Academic Article Quantitative solubilization and analysis of insoluble paired helical filaments from Alzheimer disease.
Academic Article Glycoxidation and oxidative stress in Parkinson disease and diffuse Lewy body disease.
Academic Article 4-Hydroxynonenal-derived advanced lipid peroxidation end products are increased in Alzheimer's disease.
Academic Article Levuglandin E2-protein adducts in human plasma and vasculature.
Academic Article Abnormal localization of iron regulatory protein in Alzheimer's disease.
Academic Article Cerebrovascular muscle atrophy is a feature of Alzheimer's disease.
Academic Article Cytochemical demonstration of oxidative damage in Alzheimer disease by immunochemical enhancement of the carbonyl reaction with 2,4-dinitrophenylhydrazine.
Academic Article Altered glycosylation pattern of proteins in Alzheimer disease.
Academic Article Striation is the characteristic neuritic abnormality in Alzheimer disease.
Academic Article Dimethylargininase, a nitric oxide regulatory protein, in Alzheimer disease.
Academic Article CI-ATPase and Na+/K(+)-ATPase activities in Alzheimer's disease brains.
Academic Article Parkinson's disease is associated with oxidative damage to cytoplasmic DNA and RNA in substantia nigra neurons.
Academic Article Increased neuronal glucose-6-phosphate dehydrogenase and sulfhydryl levels indicate reductive compensation to oxidative stress in Alzheimer disease.
Academic Article Quinone reductase (NQO1), a sensitive redox indicator, is increased in Alzheimer's disease.
Academic Article In Alzheimer's disease, heme oxygenase is coincident with Alz50, an epitope of tau induced by 4-hydroxy-2-nonenal modification.
Academic Article Sequestration of iron by Lewy bodies in Parkinson's disease.
Academic Article Activation and redistribution of c-jun N-terminal kinase/stress activated protein kinase in degenerating neurons in Alzheimer's disease.
Academic Article Protein disulfide isomerase in Alzheimer disease.
Academic Article Evidence for a novel heme-binding protein, HasAh, in Alzheimer disease.
Academic Article Active glycation in neurofibrillary pathology of Alzheimer disease: N(epsilon)-(carboxymethyl) lysine and hexitol-lysine.
Academic Article Alteration of proteins regulating apoptosis, Bcl-2, Bcl-x, Bax, Bak, Bad, ICH-1 and CPP32, in Alzheimer's disease.
Academic Article What are the facts and artifacts of the pathogenesis and etiology of Alzheimer disease?
Academic Article RNA oxidation is a prominent feature of vulnerable neurons in Alzheimer's disease.
Academic Article Genetic evidence for oxidative stress in Alzheimer's disease.
Academic Article Is increased redox-active iron in Alzheimer disease a failure of the copper-binding protein ceruloplasmin?
Academic Article Activation of neuronal extracellular receptor kinase (ERK) in Alzheimer disease links oxidative stress to abnormal phosphorylation.
Academic Article In situ oxidative catalysis by neurofibrillary tangles and senile plaques in Alzheimer's disease: a central role for bound transition metals.
Academic Article Neuronal RNA oxidation in Alzheimer's disease and Down's syndrome.
Academic Article Evidence that the beta-amyloid plaques of Alzheimer's disease represent the redox-silencing and entombment of abeta by zinc.
Academic Article Activation of NADPH oxidase in Alzheimer's disease brains.
Academic Article Lipoperoxidation is selectively involved in progressive supranuclear palsy.
Academic Article Activation of p38 kinase links tau phosphorylation, oxidative stress, and cell cycle-related events in Alzheimer disease.
Academic Article Neuronal oxidative stress precedes amyloid-beta deposition in Down syndrome.
Academic Article Erythrocyte, plasma, and serum antioxidant activities in untreated toxic multinodular goiter patients.
Academic Article Mitochondrial abnormalities in Alzheimer's disease.
Academic Article Abortive apoptosis in Alzheimer's disease.
Academic Article Differential activation of neuronal ERK, JNK/SAPK and p38 in Alzheimer disease: the 'two hit' hypothesis.
Academic Article Activation of MKK6, an upstream activator of p38, in Alzheimer's disease.
Academic Article Diabetes-associated sustained activation of the transcription factor nuclear factor-kappaB.
Academic Article Increase of cdk5 is related to neurofibrillary pathology in progressive supranuclear palsy.
Academic Article The mitochondrial common deletion in Parkinson's disease and related movement disorders.
Academic Article Oxidative stress and predominant Abeta42(43) deposition in myopathies with rimmed vacuoles.
Academic Article Oxidative damage is the earliest event in Alzheimer disease.
Academic Article Increased expression of NOS and ET-1 immunoreactivity in human colorectal metastatic liver tumours is associated with selective depression of constitutive NOS immunoreactivity in vessel endothelium.
Academic Article Reactive oxygen: its sources and significance in Alzheimer disease.
Academic Article Conformational changes and cleavage of tau in Pick bodies parallel the early processing of tau found in Alzheimer pathology.
Academic Article Neuronal binucleation in Alzheimer disease hippocampus.
Academic Article Phosphorylation of tau protein at sites Ser(396-404) is one of the earliest events in Alzheimer's disease and Down syndrome.
Academic Article Ra?l Mena: 1953-2014.
Academic Article Dysfunctional tubular endoplasmic reticulum constitutes a pathological feature of Alzheimer's disease.
Academic Article Phospho-Tau Protein Expression in the Cell Cycle of SH-SY5Y Neuroblastoma Cells: A Morphological Study.
Grant NEUROFIBRILLARY PATHOLOGY IN ALZHEIMER DISEASE
Academic Article Strawberry (Fragaria ananassa duch.) Alba extract attenuates DNA damage in lymphocytes of patients with Alzheimer's disease.
Academic Article Corrigendum to "Slower Dynamics and Aged Mitochondria in Sporadic Alzheimer's Disease".
Academic Article Lessons from antiamyloid-? immunotherapies in Alzheimer's disease.
Academic Article Alzheimer's Disease: Not Just for the Aged?
Academic Article Evaluation of N- and O-Linked Indole Triazines for a Dual Effect on a-Synuclein and Tau Aggregation.
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