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McCarrey, John R.
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overview Research in Dr. McCarrey’s lab is centered on mammalian germ cells and stem cells. Experimental models include the mouse, the baboon, and the opossum. The lab is interested in the epigenetic regulation of cell functions, including determination of cell fates, maintenance of genetic integrity, regulation of gene expression, genomic imprinting, X-chromosome inactivation and meiotic sex chromosome inactivation, methods of assisted reproduction, the evolution of tissue-specific gene expression in mammalian species, and developing the baboon as a model system for testing stem cell-based therapeutic applications.
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Item TypeName
Academic Article Epigenetic regulation of genetic integrity is reprogrammed during cloning.
Academic Article Spermatogenesis as a model system for developmental analysis of regulatory mechanisms associated with tissue-specific gene expression.
Academic Article Developmental patterns of PPAR and RXR gene expression during spermatogenesis.
Academic Article Multiple elements influence transcriptional regulation from the human testis-specific PGK2 promoter in transgenic mice.
Academic Article Microarray-based analysis of cell-cycle gene expression during spermatogenesis in the mouse.
Academic Article Dynamic expression pattern and subcellular localization of the Rhox10 homeobox transcription factor during early germ cell development.
Academic Article Rsx is a metatherian RNA with Xist-like properties in X-chromosome inactivation.
Academic Article Computer-assisted annotation of murine Sertoli cell small RNA transcriptome.
Academic Article Enhanced genetic integrity in mouse germ cells.
Academic Article A set of genes critical to development is epigenetically poised in mouse germ cells from fetal stages through completion of meiosis.
Academic Article Differential transcription of Pgk genes during spermatogenesis in the mouse.
Academic Article Environmentally induced transgenerational epigenetic reprogramming of primordial germ cells and the subsequent germ line.
Academic Article Protein-DNA interactions associated with the onset of testis-specific expression of the mammalian Pgk-2 gene.
Academic Article A novel class of somatic small RNAs similar to germ cell pachytene PIWI-interacting small RNAs.
Academic Article Transcriptional and translational heterogeneity among neonatal mouse spermatogonia.
Academic Article Co-regulation of pluripotency and genetic integrity at the genomic level.
Academic Article Nucleotide sequence of the promoter region of a tissue-specific human retroposon: comparison with its housekeeping progenitor.
Academic Article Parallel evolution of male germline epigenetic poising and somatic development in animals.
Academic Article EPIGENETICS. The epigenome--a family affair.
Academic Article Optimization of culture conditions for the derivation and propagation of baboon (Papio anubis) induced pluripotent stem cells.
Academic Article The Mammalian Spermatogenesis Single-Cell Transcriptome, from Spermatogonial Stem Cells to Spermatids.
Academic Article Transcriptional analysis of the candidate spermatogenesis gene Ube1y and of the closely related Ube1x shows that they are coexpressed in spermatogonia and spermatids but are repressed in pachytene spermatocytes.
Academic Article Differentiation: the selective potentiation of chromatin domains.
Academic Article Concerted regulation and molecular evolution of the duplicated SNRPB'/B and SNRPN loci.
Academic Article X-chromosome inactivation during spermatogenesis is regulated by an Xist/Tsix-independent mechanism in the mouse.
Academic Article The H19 methylation imprint is erased and re-established differentially on the parental alleles during male germ cell development.
Academic Article Three novel spermatogenesis-specific zinc finger genes.
Academic Article Conservation of Dnmt1o cytosine methyltransferase in the marsupial Monodelphis domestica.
Academic Article Ontogeny of a demethylation domain and its relationship to activation of tissue-specific transcription.
Academic Article Differential expression of sex-linked and autosomal germ-cell-specific genes during spermatogenesis in the mouse.
Academic Article Epigenetic regulation of testis-specific gene expression.
Academic Article Developmental changes in methylation of spermatogenesis-specific genes include reprogramming in the epididymis.
Academic Article Autonomous regulation of sex-specific developmental programming in mouse fetal germ cells.
Academic Article Evolutionarily conserved mammalian adenine nucleotide translocase 4 is essential for spermatogenesis.
Academic Article Expression of stimulated by retinoic acid gene 8 (Stra8) and maturation of murine gonocytes and spermatogonia induced by retinoic acid in vitro.
Academic Article In vivo analysis of developmentally and evolutionarily dynamic protein-DNA interactions regulating transcription of the Pgk2 gene during mammalian spermatogenesis.
Academic Article A conserved E2F6-binding element in murine meiosis-specific gene promoters.
Concept Gene Expression Regulation
Concept Gene Expression Regulation, Enzymologic
Concept Gene Expression Regulation, Developmental
Academic Article OGG1 protects mouse spermatogonial stem cells from reactive oxygen species in culture?.
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