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One or more keywords matched the following properties of Xie, Huan
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overview I have a strong background in drug characterization, formulation, novel delivery systems, pharmacokinetics and nanotechnology, with a focus on preclinical drug development. I have the specific training, expertise, leadership, and motivation to conduct the proposed project. Currently, I serve as the Founding Director of the Institute of Drug Discovery and Development (iD3) at TSU, which is an NCI-designated subcontractor to provide service for investigators cross the United States. I am the PI and Director of the Research Centers in Minority Institutions (RCMI) Center for Biomedical and Minority Health Research (CBMHR) supported by NIMHD. I am also co-Director of the Gulf Coast Consortia (GCC) Center for Comprehensive PK/PD and Formulation (CCPF) which is funded by the Cancer Prevention & Research Institute of Texas, known as CPRIT. I had four years of industrial experience as Senior Research Scientist working on silica/gold nanoshells for photothermal ablation cancer therapy, which has been used in several cancer clinical trials. Since joining Texas Southern University in 2008, I have successfully completed over 60 research projects, taught over 1000 Pharm.D. students, and personally mentored 10 research scientists/postdoctoral fellows, and over 30 Ph.D., Pharm.D., and undergraduate students, most of whom were underrepresented minorities (URM). I have served as Program Director of the Graduate Program of Pharmaceutical Sciences (GPPS) since 2020, focusing on mentoring the next generation of URM scientists in the field of Pharmaceutics. These trainees were highly sought by employers, such as the FDA, drug companies, hospitals, and academia. As PI or co-Investigator on several NIH- and private agency-funded grants, I laid the groundwork for the proposed research by developing novel analytical methods, advanced drug formulations, and delivery systems and establishing pharmacokinetic and biodistribution profiles. In addition, I successfully administered funded projects (e.g. staffing, research progress, budget, etc.), collaborated with other researchers from institutions across the U.S., generated patents, and produced peer-reviewed publications from these projects (see select list below). These previous experiences made me aware of the importance of frequent communication among project members, and of constructing a realistic program plan, research design, timeline, and budget. Affiliation • American Association of Pharmaceutical Scientists (AAPS) • American Association for Cancer Research (AACR) • American Association of Colleges of Pharmacy (AACP) • Rho Chi Honor Society in Pharmacy (former student advisor) • Gulf Coast Consortia (GCC) • American Chemical Society (ACS) • Phi Lambda Upsilon Honorary Chemical Society
One or more keywords matched the following items that are connected to Xie, Huan
Item TypeName
Academic Article In vivo PET imaging and biodistribution of radiolabeled gold nanoshells in rats with tumor xenografts.
Academic Article Effect of intratumoral administration on biodistribution of 64Cu-labeled nanoshells.
Concept Gold
Concept Gold Colloid
Academic Article Integrin av?3-targeted gold nanoshells augment tumor vasculature-specific imaging and therapy.
Academic Article Hypoxia-targeted gold nanorods for cancer photothermal therapy.
Grant Development of a Novel Nanoconstruct Based Photothermal Therapy for Tumor Hypoxia
Academic Article Multifunctional gold nanoparticle-peptide complexes for nuclear targeting.
Academic Article Critical flocculation concentrations, binding isotherms, and ligand exchange properties of peptide-modified gold nanoparticles studied by UV-visible, fluorescence, and time-correlated single photon counting spectroscopies.
Academic Article Assembly and characterization of biomolecule-gold nanoparticle conjugates and their use in intracellular imaging.
Academic Article Preparation of protein gradients through the controlled deposition of protein-nanoparticle conjugates onto functionalized surfaces.
Academic Article Cellular trajectories of peptide-modified gold particle complexes: comparison of nuclear localization signals and peptide transduction domains.
Academic Article Quantitative estimation of gold nanoshell concentrations in whole blood using dynamic light scattering.
Academic Article Nanoimaging - Biomedical Nanotechnology Book series
Search Criteria
  • Gold
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