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Kandimalla, Karunya
One or more keywords matched the following items that are connected to
Kandimalla, Karunya
Item Type
Name
Academic Article
Mechanism of neuronal versus endothelial cell uptake of Alzheimer's disease amyloid beta protein.
Academic Article
Chitosan enhances the stability and targeting of immuno-nanovehicles to cerebro-vascular deposits of Alzheimer's disease amyloid protein.
Academic Article
Surface plasmon resonance binding kinetics of Alzheimer's disease amyloid beta peptide-capturing and plaque-binding monoclonal antibodies.
Academic Article
HH domain of Alzheimer's disease Abeta provides structural basis for neuronal binding in PC12 and mouse cortical/hippocampal neurons.
Academic Article
Traffic jam at the blood-brain barrier promotes greater accumulation of Alzheimer's disease amyloid-? proteins in the cerebral vasculature.
Academic Article
Alzheimer's disease amyloid ?-protein mutations and deletions that define neuronal binding/internalization as early stage nonfibrillar/fibrillar aggregates and late stage fibrils.
Academic Article
Differences in the cellular uptake and intracellular itineraries of amyloid beta proteins 40 and 42: ramifications for the Alzheimer's drug discovery.
Academic Article
Engineering theranostic nanovehicles capable of targeting cerebrovascular amyloid deposits.
Academic Article
Insulin differentially affects the distribution kinetics of amyloid beta 40 and 42 in plasma and brain.
Academic Article
Differential Effects of Alzheimer's Disease A?40 and 42 on Endocytosis and Intraneuronal Trafficking.
Academic Article
Cationic carrier peptide enhances cerebrovascular targeting of nanoparticles in Alzheimer's disease brain.
Academic Article
Amyloid-? Peptides Disrupt Interactions Between VAMP-2 and SNAP-25 in Neuronal Cells as Determined by FRET/FLIM.
Academic Article
Amyloid-beta impairs insulin signaling by accelerating autophagy-lysosomal degradation of LRP-1 and IR-? in blood-brain barrier endothelial cells in vitro and in 3XTg-AD mice.
Academic Article
Pharmacokinetic analysis of the blood-brain barrier transport of 125I-amyloid beta protein 40 in wild-type and Alzheimer's disease transgenic mice (APP,PS1) and its implications for amyloid plaque formation.
Academic Article
Physiological and biophysical factors that influence Alzheimer's disease amyloid plaque targeting of native and putrescine modified human amyloid beta40.
Academic Article
Pharmacokinetics and amyloid plaque targeting ability of a novel peptide-based magnetic resonance contrast agent in wild-type and Alzheimer's disease transgenic mice.
Academic Article
In vivo targeting of antibody fragments to the nervous system for Alzheimer's disease immunotherapy and molecular imaging of amyloid plaques.
Academic Article
Selective contrast enhancement of individual Alzheimer's disease amyloid plaques using a polyamine and Gd-DOTA conjugated antibody fragment against fibrillar Abeta42 for magnetic resonance molecular imaging.
Concept
Peptides
Academic Article
High-Density Lipoprotein Mimetic Peptide 4F Efficiently Crosses the Blood-Brain Barrier and Modulates Amyloid-? Distribution between Brain and Plasma.
Academic Article
Distinct Uptake Kinetics of Alzheimer Disease Amyloid-? 40 and 42 at the Blood-Brain Barrier Endothelium.
Academic Article
Age-Dependent Changes in the Plasma and Brain Pharmacokinetics of Amyloid-? Peptides and Insulin.
Academic Article
Semimechanistic Population Pharmacokinetic Modeling to Investigate Amyloid Beta Trafficking and Accumulation at the BBB Endothelium.
Academic Article
Amyloid-Beta Peptides 40 and 42 Employ Distinct Molecular Pathways for Cell Entry and Intracellular Transit at the Blood-Brain Barrier Endothelium.
Search Criteria
Peptides