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Academic Article
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Simultaneous RP-HPLC-DAD quantification of bromocriptine, haloperidol and its diazepane structural analog in rat plasma with droperidol as internal standard for application to drug-interaction pharmacokinetics.
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Academic Article
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Evaluation of the behavioral and pharmacokinetic profile of SYA013, a homopiperazine analog of haloperidol in rats.
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Academic Article
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Multi-receptor drug design: Haloperidol as a scaffold for the design and synthesis of atypical antipsychotic agents.
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Academic Article
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Structure-activity relationship studies of SYA 013, a homopiperazine analog of haloperidol.
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Academic Article
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Evaluation of the potential of antipsychotic agents to induce catalepsy in rats: assessment of a new, commercially available, semi-automated instrument.
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Academic Article
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Further evaluation of the tropane analogs of haloperidol.
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Academic Article
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Detection of a neurotoxic quaternary pyridinium metabolite in the liver of haloperidol-treated rats.
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Academic Article
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SYA 013 analogs as moderately selective sigma-2 (s2) ligands: Structure-affinity relationship studies.
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Academic Article
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New analogs of SYA013 as sigma-2 ligands with anticancer activity.
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Academic Article
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The acute EPS of haloperidol may be unrelated to its metabolic transformation to BCPP+.
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Academic Article
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Design, synthesis, and evaluation of metabolism-based analogues of haloperidol incapable of forming MPP+-like species.
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Academic Article
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Haloperidol: towards further understanding of the structural contributions of its pharmacophoric elements at D2-like receptors.
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Academic Article
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Evaluation of the eutomer of 4-{3-(4-chlorophenyl)-3-hydroxypyrrolidin-1-yl}-1-(4-fluorophenyl)butan-1-one, {(+)-SYA 09}, a pyrrolidine analog of haloperidol.
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Academic Article
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Identification of a butyrophenone analog as a potential atypical antipsychotic agent: 4-[4-(4-chlorophenyl)-1,4-diazepan-1-yl]-1-(4-fluorophenyl)butan-1-one.
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Academic Article
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Synthesis and evaluation of ligands for D2-like receptors: the role of common pharmacophoric groups.
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Concept
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Haloperidol
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Academic Article
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A Mechanistic Investigation on the Anticancer Properties of SYA013, a Homopiperazine Analogue of Haloperidol with Activity against Triple Negative Breast Cancer Cells.
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Academic Article
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An Evaluation of the Anticancer Properties of SYA014, a Homopiperazine-Oxime Analog of Haloperidol in Triple Negative Breast Cancer Cells.
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