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Quirk, Gregory J.

One or more keywords matched the following properties of Quirk, Gregory J.

Property	Value
keywords	avoidance
overview	My research focuses on the neural circuits of fear regulation, using rodent and human models of fear conditioning, extinction, and active avoidance. My lab uses a variety of experimental techniques including multichannel unit recording, optogenetics, immunocytochemistry, electrical stimulation, and computational modeling. We focus on how the prefrontal cortex influences fear-related activity in the amygdala, thalamus and striatum. This work is applicable to PTSD and OCD, and is funded by the National Institute of Mental Health. My lab has been in Puerto Rico for 18 years and consists of approximately 14 students, post-docs, and technicians, from the U.S., Puerto Rico, and other parts of Latin America. My long-term goal is to promote neuroscience research and training in Latin America.

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Value

keywords

avoidance

overview

My research focuses on the neural circuits of fear regulation, using rodent and human models of fear conditioning, extinction, and active avoidance. My lab uses a variety of experimental techniques including multichannel unit recording, optogenetics, immunocytochemistry, electrical stimulation, and computational modeling. We focus on how the prefrontal cortex influences fear-related activity in the amygdala, thalamus and striatum. This work is applicable to PTSD and OCD, and is funded by the National Institute of Mental Health. My lab has been in Puerto Rico for 18 years and consists of approximately 14 students, post-docs, and technicians, from the U.S., Puerto Rico, and other parts of Latin America. My long-term goal is to promote neuroscience research and training in Latin America.

One or more keywords matched the following items that are connected to Quirk, Gregory J.

Item Type	Name
Academic Article	Signaling aversive events in the midbrain: worse than expected.
Academic Article	Neural structures mediating expression and extinction of platform-mediated avoidance.
Academic Article	Persistent active avoidance correlates with activity in prelimbic cortex and ventral striatum.
Academic Article	An Avoidance-Based Rodent Model of Exposure With Response Prevention Therapy for Obsessive-Compulsive Disorder.
Academic Article	Active avoidance requires inhibitory signaling in the rodent prelimbic prefrontal cortex.
Academic Article	Alteration of BDNF in the medial prefrontal cortex and the ventral hippocampus impairs extinction of avoidance.
Academic Article	Prefrontal circuits signaling active avoidance?retrieval and extinction.
Academic Article	Individual variability in behavior and functional networks predicts vulnerability using an animal model of PTSD.
Academic Article	The study of active avoidance: A platform for discussion.
Academic Article	Prolonged avoidance training exacerbates OCD-like behaviors in a rodent model.
Academic Article	Inhibition of the amygdala: key to pathological states?
Academic Article	The role of ventromedial prefrontal cortex in the recovery of extinguished fear.
Concept	Avoidance Learning
Academic Article	Neural mechanisms of persistent avoidance in OCD: A novel avoidance devaluation study.
Academic Article	Divergent projections of the prelimbic cortex bidirectionally regulate active avoidance.
Academic Article	Characterizing Different Strategies for Resolving Approach-Avoidance Conflict.
Grant	Prefrontal amygdala interactions in fear conditioning
Academic Article	A Novel Insular/Orbital-Prelimbic Circuit That Prevents Persistent Avoidance in a Rodent Model of Compulsive Behavior.
Academic Article	Specific patterns of endogenous functional connectivity are associated with harm avoidance in OCD.

Search Criteria

avoidance

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