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One or more keywords matched the following properties of Ruan, Jianhua
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overview My research interests lie in the broad area of bioinformatics, computational systems biology, and data mining. More specifically, my current research is focused on the following three directions: (1) module discovery and analysis in complex networks, with applications in protein complex prediction and microarray data clustering; (2) modeling and analysis of transcriptional/post-transcriptional regulatory networks (e.g. DNA motif finding and ChIP-seq data analysis); and (3) network-based biomarker discovery and disease classification via integrated analysis of heterogonous functional genomics data such as gene expression, protein-protein interactions, and microRNA-mRNA interactions. My research has been sponsored by NIH, NSF, and the San Antonio Life Sciences Institute.
One or more keywords matched the following items that are connected to Ruan, Jianhua
Item TypeName
Academic Article An ensemble learning approach to reverse-engineering transcriptional regulatory networks from time-series gene expression data.
Academic Article A top-performing algorithm for the DREAM3 gene expression prediction challenge.
Academic Article A systems biology approach to the identification and analysis of transcriptional regulatory networks in osteocytes.
Academic Article A novel swarm intelligence algorithm for finding DNA motifs.
Academic Article Systematic identification of functional modules and cis-regulatory elements in Arabidopsis thaliana.
Academic Article A novel link prediction algorithm for reconstructing protein-protein interaction networks by topological similarity.
Academic Article A genome-wide cis-regulatory element discovery method based on promoter sequences and gene co-expression networks.
Academic Article Network-based Pathway Enrichment Analysis.
Academic Article An Ensemble Approach for Drug Side Effect Prediction.
Academic Article A personalized committee classification approach to improving prediction of breast cancer metastasis.
Academic Article Computational modeling of in vivo and in vitro protein-DNA interactions by multiple instance learning.
Academic Article Logo2PWM: a tool to convert sequence logo to position weight matrix.
Academic Article Comparative evaluation of network features for the prediction of breast cancer metastasis.
Concept Computational Biology
Academic Article An iterated loop matching approach to the prediction of RNA secondary structures with pseudoknots.
Academic Article A bi-dimensional regression tree approach to the modeling of gene expression regulation.
Academic Article CAGER: classification analysis of gene expression regulation using multiple information sources.
Academic Article Cis-regulatory element based targeted gene finding: genome-wide identification of abscisic acid- and abiotic stress-responsive genes in Arabidopsis thaliana.
Academic Article Building and analyzing protein interactome networks by cross-species comparisons.
Academic Article Robust edge-based biomarker discovery improves prediction of breast cancer metastasis.
Academic Article Spatial mapping of single cells in the Drosophila embryo from transcriptomic data based on topological consistency.
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  • Bioinformatics
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