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McCarrey, John R.
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overview Research in Dr. McCarrey’s lab is centered on mammalian germ cells and stem cells. Experimental models include the mouse, the baboon, and the opossum. The lab is interested in the epigenetic regulation of cell functions, including determination of cell fates, maintenance of genetic integrity, regulation of gene expression, genomic imprinting, X-chromosome inactivation and meiotic sex chromosome inactivation, methods of assisted reproduction, the evolution of tissue-specific gene expression in mammalian species, and developing the baboon as a model system for testing stem cell-based therapeutic applications.
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Item TypeName
Academic Article Epigenetic regulation of genetic integrity is reprogrammed during cloning.
Academic Article Sex chromosome inactivation in the male.
Academic Article Primary epimutations introduced during intracytoplasmic sperm injection (ICSI) are corrected by germline-specific epigenetic reprogramming.
Academic Article The epigenome as a target for heritable environmental disruptions of cellular function.
Academic Article Environmentally induced transgenerational epigenetic reprogramming of primordial germ cells and the subsequent germ line.
Academic Article Distinctions between transgenerational and non-transgenerational epimutations.
Academic Article Parallel evolution of male germline epigenetic poising and somatic development in animals.
Academic Article Pluripotent cells display enhanced resistance to mutagenesis.
Academic Article EPIGENETICS. The epigenome--a family affair.
Academic Article Corrigendum: Parallel evolution of male germline epigenetic poising and somatic development in animals.
Academic Article Tertiary Epimutations - A Novel Aspect of Epigenetic Transgenerational Inheritance Promoting Genome Instability.
Academic Article Transgenerational sperm DNA methylation epimutation developmental origins following ancestral vinclozolin exposure.
Academic Article Epigenetic regulation of testis-specific gene expression.
Academic Article Unique Epigenetic Programming Distinguishes Regenerative Spermatogonial Stem Cells in the Developing Mouse Testis.
Academic Article Germ cells: ENCODE's forgotten cell type?.
Academic Article Epigenetic priming as a mechanism of predetermination of spermatogonial stem cell fate.
Academic Article The epigenetic mechanisms underlying gamete origin of adult-onset diseases.
Academic Article Profiling the Epigenetic Landscape of the Spermatogonial Stem Cell: Part 2-Computational Analysis of Epigenomics Data.
Academic Article Profiling the Epigenetic Landscape of the Spermatogonial Stem Cell-Part 1: Epigenomics Assays.
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  • Epigenetics
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