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Schiaffino, Melody
Person
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Metformin induces a senescence-associated gene signature in breast cancer cells.
Academic Article
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p53 is required for metformin-induced growth inhibition, senescence and apoptosis in breast cancer cells.
Academic Article
Why?
Id4 promotes senescence and sensitivity to doxorubicin-induced apoptosis in DU145 prostate cancer cells.
Academic Article
Why?
Zbtb7a suppresses prostate cancer through repression of a Sox9-dependent pathway for cellular senescence bypass and tumor invasion.
Academic Article
Why?
Physiologic frailty as a sign of accelerated aging among adult survivors of childhood cancer: a report from the St Jude Lifetime cohort study.
Academic Article
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Braun, Kathryn L.
Person
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Building capacity for cancer surveillance and public health research: The Cancer Task Force Project for Cooperation in the Caribbean and Aging Research.
Academic Article
Why?
Co-targeting SKP2 and KDM5B inhibits prostate cancer progression by abrogating AKT signaling with induction of senescence and apoptosis.
Academic Article
Why?
Inhibition of protein kinase C delta leads to cellular senescence to induce anti-tumor effects in colorectal cancer.
Academic Article
Why?
Host age is a systemic regulator of gene expression impacting cancer progression.
Academic Article
Why?
A novel type of cellular senescence that can be enhanced in mouse models and human tumor xenografts to suppress prostate tumorigenesis.
Academic Article
Why?
The KDM5 inhibitor PBIT reduces proliferation of castration-resistant prostate cancer cells via cell cycle arrest and the induction of senescence.
Academic Article
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Sharma, Sudha
Person
Why?
Chitrala, Kumaraswamy Naidu
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