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One or more keywords matched the following properties of Appleyard, Caroline
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overview Caroline B. Appleyard, PhD is a Professor in the Department of Basic Sciences (Physiology Division) and Internal Medicine at Ponce Health Sciences University (PHSU) - Ponce Research Institute. She obtained her Bachelor’s degree in Pharmacology from the University of Edinburgh, Scotland before completing her doctoral studies at the University of Southampton, England. She then gained extensive experience in the field of gastrointestinal inflammation, through her post-doctoral studies at the University of Calgary, Canada and at the University of South Dakota. Her current studies center on the interactions between inflammatory mediators, microflora, and behavior, in the pathogenesis and exacerbation of inflammatory conditions of the intestine. She has developed several animal models to study these conditions and help elucidate the neuro-immune mechanisms involved with a view to developing complementary therapies. Dr. Appleyard strongly believes that mentoring and exposure to training, and learning from others experiences will help to ensure that women and minorities stay in science. At PHSU she is heavily involved in scientific training in her capacity as Program Director of the NIGMS RISE graduate training program, and co-leader for the Research Education Core of the U54 PSM-Moffitt Cancer Center partnership, and this extends to her involvement in mentoring programs at the national level. Most recently she was recognized at the national level becoming the Inaugural recipient of the A. Clifford Barger Underrepresented Minority Mentorship Award from the American Physiological Society. She regularly reviews for academic journals and funding agencies and has coordinated several scientific workshops and meetings. She is an active member of several professional societies including the American Physiological Society (currently Chair of the Career Opportunities in Physiology Committee; Past-President of the Puerto Rico Physiological Society), the American Gastroenterology Association, the American Association for Cancer Research and the Association for Women In Science.
One or more keywords matched the following items that are connected to Appleyard, Caroline
Item TypeName
Grant Physical activity as a therapeutic intervention in endometriosis
Grant Stress: Potential Impact on an Animal Model of Endometriosis
Academic Article Pretreatment with the probiotic VSL#3 delays transition from inflammation to dysplasia in a rat model of colitis-associated cancer.
Academic Article Gut microbial diversity is reduced by the probiotic VSL#3 and correlates with decreased TNBS-induced colitis.
Academic Article Effect of a neurokinin-1 receptor antagonist in a rat model of colitis-associated colon cancer.
Academic Article Erlotinib inhibits progression to dysplasia in a colitis-associated colon cancer model.
Academic Article Stress exacerbates endometriosis manifestations and inflammatory parameters in an animal model.
Academic Article Stress management affects outcomes in the pathophysiology of an endometriosis model.
Academic Article Double immunofluorescent staining of rat macrophages in formalin-fixed paraffin-embedded tissue using two monoclonal mouse antibodies.
Academic Article Colonic macrophage polarization in homeostasis, inflammation, and cancer.
Academic Article Impact of Psychological Stress on Pain Perception in an Animal Model of Endometriosis.
Academic Article Endometriosis Is Associated With a Shift in MU Opioid and NMDA Receptor Expression in the Brain Periaqueductal Gray.
Academic Article Impact of physical activity on pain perception in an animal model of endometriosis.
Academic Article The Probiotic VSL#3 Modulates Colonic Macrophages, Inflammation, and Microflora in Acute Trinitrobenzene Sulfonic Acid Colitis.
Academic Article Antagonizing the corticotropin releasing hormone receptor 1 with antalarmin reduces the progression of endometriosis.
Academic Article Stress During Development of Experimental Endometriosis Influences Nerve Growth and Disease Progression.
Academic Article Environmental Manipulations as an Effective Alternative Treatment to Reduce Endometriosis Progression.
Academic Article Infusion of HIV-1 Nef-expressing astrocytes into the rat hippocampus induces enteropathy and interstitial pneumonitis and increases blood-brain-barrier permeability.
Academic Article Inhibition of Histone Methyltransferase EZH2 Suppresses Endometriotic Vesicle Development in a Rat Model of Endometriosis.
Academic Article Short treatment with antalarmin alters adrenal gland receptors in the rat model of endometriosis.
Academic Article The Link Between Stress and Endometriosis: from Animal Models to the Clinical Scenario.
Academic Article Influence of Stress on the Vitamin D-Vitamin D Receptor System, Macrophages, and the Local Inflammatory Milieu in Endometriosis.
Academic Article Temporal changes in colonic vascular architecture and inflammatory mediator levels in animal models of colitis.
Academic Article Bacterial load in animal models of acute and chronic 'reactivated' colitis.
Academic Article Effect of bacterial chemotactic peptides on intestinal inflammation in animal models of acute and chronic "relapsed" colitis.
Academic Article Role of tumor necrosis factor receptors in an animal model of acute colitis.
Academic Article Molecular profiling of experimental endometriosis identified gene expression patterns in common with human disease.
Academic Article Experimental intestinal endometriosis is characterized by increased levels of soluble TNFRSF1B and downregulation of Tnfrsf1a and Tnfrsf1b gene expression.
Academic Article Regional variations in neurokinin receptor subtype contributions to muscularis mucosae and epithelial function in rat colon.
Academic Article Molecular profiling of a rat model of colitis: validation of known inflammatory genes and identification of novel disease-associated targets.
Academic Article Prolonged chronic inflammation progresses to dysplasia in a novel rat model of colitis-associated colon cancer.
Academic Article An angiotensin II receptor antagonist reduces inflammatory parameters in two models of colitis.
Academic Article Chronic inflammation alters the contribution of neurokinin receptor subtypes to epithelial function in rat colon.
Academic Article Experimental endometriosis in the rat is correlated with colonic motor function alterations but not with bacterial load.
Concept Animals
Concept Animal Feed
Concept Behavior, Animal
Concept Disease Models, Animal
Concept Housing, Animal
Concept Models, Animal
Academic Article Reactivation of hapten-induced colitis and its prevention by anti-inflammatory drugs.
Academic Article Hapten-induced chronic colitis in the rat: alternatives to trinitrobenzene sulfonic acid.
Academic Article Tumor necrosis factor mediation of NSAID-induced gastric damage: role of leukocyte adherence.
Academic Article NO-naproxen vs. naproxen: ulcerogenic, analgesic and anti-inflammatory effects.
Academic Article TNF-alpha facilitates inflammation-induced glucocorticoid secretion in rats with biliary obstruction.
Academic Article TNF-alpha contributes to the pathogenesis of ethanol-induced gastric damage in cirrhotic rats.
Academic Article Experimental colitis increases blood-brain barrier permeability in rabbits.
Academic Article Endogenous glucocorticoids released during acute toxic liver injury enhance hepatic IL-10 synthesis and release.
Academic Article Temporal patterns of colonic blood flow and tissue damage in an animal model of colitis.
Academic Article Persistent epithelial dysfunction and bacterial translocation after resolution of intestinal inflammation.
Academic Article Metabolomics in endometriosis: challenges and perspectives for future studies.
Academic Article Beyond depression and anxiety; a systematic review about the role of corticotropin-releasing hormone antagonists in diseases of the pelvic and abdominal organs.
Academic Article Voluntary Wheel Running Reduces Vesicle Development in an Endometriosis Animal Model Through Modulation of Immune Parameters.
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