This page shows the details of why an item matched the keywords from your search.
| Item Type | Name |
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Grant
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HOST CELL INVASION BY TRYPANOSOMA CRUZI
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Grant
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Molecular Analysis of Trypanosome Infection
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Grant
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Molecular Analysis of Trypanosome Infection
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Academic Article
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Crystal structures of Trypanosoma brucei sterol 14alpha-demethylase and implications for selective treatment of human infections.
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Academic Article
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VNI cures acute and chronic experimental Chagas disease.
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Academic Article
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Cocaine enhances HIV-1-induced CD4(+) T-cell apoptosis: implications in disease progression in cocaine-abusing HIV-1 patients.
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Academic Article
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Structural basis for rational design of inhibitors targeting Trypanosoma cruzi sterol 14a-demethylase: two regions of the enzyme molecule potentiate its inhibition.
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Academic Article
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VFV as a New Effective CYP51 Structure-Derived Drug Candidate for Chagas Disease and Visceral Leishmaniasis.
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Academic Article
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Clinical Candidate VT-1161's Antiparasitic Effect In Vitro, Activity in a Murine Model of Chagas Disease, and Structural Characterization in Complex with the Target Enzyme CYP51 from Trypanosoma cruzi.
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Academic Article
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Sterol 14a-Demethylase Structure-Based Design of VNI (( R)- N-(1-(2,4-Dichlorophenyl)-2-(1 H-imidazol-1-yl)ethyl)-4-(5-phenyl-1,3,4-oxadiazol-2-yl)benzamide)) Derivatives To Target Fungal Infections: Synthesis, Biological Evaluation, and Crystallographic Analysis.
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Academic Article
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Sterol 14a-Demethylase Structure-Based Optimization of Drug Candidates for Human Infections with the Protozoan Trypanosomatidae.
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Academic Article
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Poly (ADP-Ribose) Polymerase-1 (PARP-1) Induction by Cocaine Is Post-Transcriptionally Regulated by miR-125b.
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Academic Article
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Phospho-proteomic analysis of primary human colon epithelial cells during the early Trypanosoma cruzi infection phase.
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Academic Article
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Successful Aspects of the Coadministration of Sterol 14a-Demethylase Inhibitor VFV and Benznidazole in Experimental Mouse Models of Chagas Disease Caused by the Drug-Resistant Strain of Trypanosoma cruzi.
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Academic Article
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Cocaine-regulated microRNA miR-124 controls poly (ADP-ribose) polymerase-1 expression in neuronal cells.
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Academic Article
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Thrombospondin-1 Plays an Essential Role in Yes-Associated Protein Nuclear Translocation during the Early Phase of Trypanosoma cruzi Infection in Heart Endothelial Cells.
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Academic Article
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Molecular cloning of a Trypanosoma cruzi cell surface casein kinase II substrate, Tc-1, involved in cellular infection.
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Concept
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Disease Models, Animal
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Concept
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Models, Biological
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Concept
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Models, Molecular
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Concept
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Cocaine-Related Disorders
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Concept
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Models, Animal
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Concept
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Rats
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Academic Article
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Thrombospondin-1 expression and modulation of Wnt and hippo signaling pathways during the early phase of Trypanosoma cruzi infection of heart endothelial cells.
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- Cocaine addiction
- rat
- model