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Perry, George

One or more keywords matched the following items that are connected to Perry, George

Item Type	Name
Academic Article	Hydroxynonenal-generated crosslinking fluorophore accumulation in Alzheimer disease reveals a dichotomy of protein turnover.
Academic Article	High molecular weight neurofilament proteins are physiological substrates of adduction by the lipid peroxidation product hydroxynonenal.
Academic Article	Hydroxynonenal adducts indicate a role for lipid peroxidation in neocortical and brainstem Lewy bodies in humans.
Academic Article	Formation of aberrant phosphotau fibrillar polymers in neural cultured cells.
Academic Article	4-hydroxynonenal contributes to NGF withdrawal-induced neuronal apoptosis.
Academic Article	Oxidative damage in cultured human olfactory neurons from Alzheimer's disease patients.
Academic Article	Oxidative stress increases expression and activity of BACE in NT2 neurons.
Academic Article	Hydroxynonenal, toxic carbonyls, and Alzheimer disease.
Academic Article	Regulation of glycogen synthase kinase-3beta by products of lipid peroxidation in human neuroblastoma cells.
Academic Article	Tau modifiers as therapeutic targets for Alzheimer's disease.
Academic Article	Alzheimer-specific epitopes of tau represent lipid peroxidation-induced conformations.
Academic Article	4-Oxo-2-nonenal is both more neurotoxic and more protein reactive than 4-hydroxy-2-nonenal.
Academic Article	Metal ions and oxidative protein modification in neurological disease.
Academic Article	Lipid peroxidation and 4-hydroxy-2-nonenal formation by copper ion bound to amyloid-beta peptide.
Academic Article	The essential role of ERK in 4-oxo-2-nonenal-mediated cytotoxicity in SH-SY5Y human neuroblastoma cells.
Academic Article	Oxidative stress is an early event in hydrostatic pressure induced retinal ganglion cell damage.
Concept	Aldehydes
Academic Article	Neurofilaments are the major neuronal target of hydroxynonenal-mediated protein cross-links.
Academic Article	4-Hydroxynonenal-derived advanced lipid peroxidation end products are increased in Alzheimer's disease.
Academic Article	Amyloid-beta deposition in Alzheimer transgenic mice is associated with oxidative stress.
Academic Article	In situ methods for detection and localization of markers of oxidative stress: application in neurodegenerative disorders.
Academic Article	In Alzheimer's disease, heme oxygenase is coincident with Alz50, an epitope of tau induced by 4-hydroxy-2-nonenal modification.
Academic Article	Increased levels of oxidative stress markers detected in the brains of mice devoid of prion protein.
Academic Article	Early glycoxidation damage in brains from Down's syndrome.
Academic Article	Lipoperoxidation is selectively involved in progressive supranuclear palsy.
Academic Article	Phosphorylated, but not native, tau protein assembles following reaction with the lipid peroxidation product, 4-hydroxy-2-nonenal.
Academic Article	Beta-site APP cleaving enzyme up-regulation induced by 4-hydroxynonenal is mediated by stress-activated protein kinases pathways.

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