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Deficiency in Six2 during prenatal development is associated with reduced nephron number, chronic renal failure, and hypertension in Br/+ adult mice.
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has minor subject area list Animals; Down-Regulation; Endothelin-1; Gene Expression Regulation, Developmental; Kidney Glomerulus; Kidney Tubules; Mice; Mice, Inbred C3H; Mice, Mutant Strains; Microscopy, Electron; Receptors, Endothelin; Sodium-Potassium-Exchanging ATPase
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  • Receptor Endothelin A
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