RCMI Coordinating Center (RCMI CC) Header Logo

Connection

Suranganie Dharmawardhane to Humans

This is a "connection" page, showing publications Suranganie Dharmawardhane has written about Humans.
Connection Strength

0.439
  1. Cruz-Collazo AM, Katsara O, Grafals-Ruiz N, Colon Gonzalez J, Dorta-Estremera S, Carlo VP, Chorna N, Schneider RJ, Dharmawardhane S. Novel Inhibition of Central Carbon Metabolism Pathways by Rac and CDC42 inhibitor MBQ167 and Paclitaxel. Mol Cancer Ther. 2024 Nov 04; 23(11):1613-1625.
    View in: PubMed
    Score: 0.041
  2. Cruz-Collazo A, Ruiz-Calderon JF, Picon H, Borrero-Garcia LD, Lopez I, Castillo-Pichardo L, Del Mar Maldonado M, Duconge J, Medina JI, Bayro MJ, Hern?ndez-O'Farrill E, Vlaar CP, Dharmawardhane S. Efficacy of Rac and Cdc42 Inhibitor MBQ-167 in Triple-negative Breast Cancer. Mol Cancer Ther. 2021 12; 20(12):2420-2432.
    View in: PubMed
    Score: 0.033
  3. Borrero-Garc?a LD, Del Mar Maldonado M, Medina-Vel?zquez J, Troche-Torres AL, Velazquez L, Grafals-Ruiz N, Dharmawardhane S. Rac inhibition as a novel therapeutic strategy for EGFR/HER2 targeted therapy resistant breast cancer. BMC Cancer. 2021 Jun 01; 21(1):652.
    View in: PubMed
    Score: 0.032
  4. Maldonado MDM, Dharmawardhane S. Targeting Rac and Cdc42 GTPases in Cancer. Cancer Res. 2018 06 15; 78(12):3101-3111.
    View in: PubMed
    Score: 0.026
  5. Humphries-Bickley T, Castillo-Pichardo L, Hernandez-O'Farrill E, Borrero-Garcia LD, Forestier-Roman I, Gerena Y, Blanco M, Rivera-Robles MJ, Rodriguez-Medina JR, Cubano LA, Vlaar CP, Dharmawardhane S. Characterization of a Dual Rac/Cdc42 Inhibitor MBQ-167 in Metastatic Cancer. Mol Cancer Ther. 2017 05; 16(5):805-818.
    View in: PubMed
    Score: 0.024
  6. Rivera Rivera A, Castillo-Pichardo L, Gerena Y, Dharmawardhane S. Anti-Breast Cancer Potential of Quercetin via the Akt/AMPK/Mammalian Target of Rapamycin (mTOR) Signaling Cascade. PLoS One. 2016; 11(6):e0157251.
    View in: PubMed
    Score: 0.023
  7. de la Parra C, Castillo-Pichardo L, Cruz-Collazo A, Cubano L, Redis R, Calin GA, Dharmawardhane S. Soy Isoflavone Genistein-Mediated Downregulation of miR-155 Contributes to the Anticancer Effects of Genistein. Nutr Cancer. 2016; 68(1):154-64.
    View in: PubMed
    Score: 0.022
  8. de la Parra C, Borrero-Garcia LD, Cruz-Collazo A, Schneider RJ, Dharmawardhane S. Equol, an isoflavone metabolite, regulates cancer cell viability and protein synthesis initiation via c-Myc and eIF4G. J Biol Chem. 2015 Mar 06; 290(10):6047-57.
    View in: PubMed
    Score: 0.021
  9. Dharmawardhane S, Hernandez E, Vlaar C. Development of EHop-016: a small molecule inhibitor of Rac. Enzymes. 2013; 33 Pt A:117-46.
    View in: PubMed
    Score: 0.019
  10. de la Parra C, Otero-Franqui E, Martinez-Montemayor M, Dharmawardhane S. The soy isoflavone equol may increase cancer malignancy via up-regulation of eukaryotic protein synthesis initiation factor eIF4G. J Biol Chem. 2012 Dec 07; 287(50):41640-50.
    View in: PubMed
    Score: 0.018
  11. Montalvo-Ortiz BL, Castillo-Pichardo L, Hern?ndez E, Humphries-Bickley T, De la Mota-Peynado A, Cubano LA, Vlaar CP, Dharmawardhane S. Characterization of EHop-016, novel small molecule inhibitor of Rac GTPase. J Biol Chem. 2012 Apr 13; 287(16):13228-38.
    View in: PubMed
    Score: 0.017
  12. Castillo-Pichardo L, Dharmawardhane SF. Grape polyphenols inhibit Akt/mammalian target of rapamycin signaling and potentiate the effects of gefitinib in breast cancer. Nutr Cancer. 2012; 64(7):1058-69.
    View in: PubMed
    Score: 0.017
  13. Mart?nez-Montemayor MM, Acevedo RR, Otero-Franqui E, Cubano LA, Dharmawardhane SF. Ganoderma lucidum (Reishi) inhibits cancer cell growth and expression of key molecules in inflammatory breast cancer. Nutr Cancer. 2011; 63(7):1085-94.
    View in: PubMed
    Score: 0.016
  14. Mart?nez-Montemayor MM, Otero-Franqui E, Martinez J, De La Mota-Peynado A, Cubano LA, Dharmawardhane S. Individual and combined soy isoflavones exert differential effects on metastatic cancer progression. Clin Exp Metastasis. 2010 Oct; 27(7):465-80.
    View in: PubMed
    Score: 0.015
  15. Castillo-Pichardo L, Mart?nez-Montemayor MM, Mart?nez JE, Wall KM, Cubano LA, Dharmawardhane S. Inhibition of mammary tumor growth and metastases to bone and liver by dietary grape polyphenols. Clin Exp Metastasis. 2009; 26(6):505-16.
    View in: PubMed
    Score: 0.014
  16. Azios NG, Krishnamoorthy L, Harris M, Cubano LA, Cammer M, Dharmawardhane SF. Estrogen and resveratrol regulate Rac and Cdc42 signaling to the actin cytoskeleton of metastatic breast cancer cells. Neoplasia. 2007 Feb; 9(2):147-58.
    View in: PubMed
    Score: 0.012
  17. Baugher PJ, Krishnamoorthy L, Price JE, Dharmawardhane SF. Rac1 and Rac3 isoform activation is involved in the invasive and metastatic phenotype of human breast cancer cells. Breast Cancer Res. 2005; 7(6):R965-74.
    View in: PubMed
    Score: 0.011
  18. Baker MJ, Zhang S, Zhang D, Searle J, Lal P, Vlaar CP, Dharmawardhane S, Abba MC, Kazanietz MG, Cooke M. VAV2 Drives EGFR-Mediated Rac1 Responses in Prostate Cancer. Mol Cancer Res. 2025 Aug 04; 23(8):684-698.
    View in: PubMed
    Score: 0.011
  19. Azios NG, Dharmawardhane SF. Resveratrol and estradiol exert disparate effects on cell migration, cell surface actin structures, and focal adhesion assembly in MDA-MB-231 human breast cancer cells. Neoplasia. 2005 Feb; 7(2):128-40.
    View in: PubMed
    Score: 0.010
  20. Lacourt-Ventura MY, Vilanova-Cuevas B, Rivera-Rodr?guez D, Rosario-Acevedo R, Miranda C, Maldonado-Mart?nez G, Maysonet J, Vargas D, Ruiz Y, Hunter-Mellado R, Cubano LA, Dharmawardhane S, Lampe JW, Baerga-Ortiz A, Godoy-Vitorino F, Mart?nez-Montemayor MM. Soy and Frequent Dairy Consumption with Subsequent Equol Production Reveals Decreased Gut Health in a Cohort of Healthy Puerto Rican Women. Int J Environ Res Public Health. 2021 08 04; 18(16).
    View in: PubMed
    Score: 0.008
  21. Al-Jawadi A, Rasha F, Ramalingam L, Alhaj S, Moussa H, Gollahon L, Dharmawardhane S, Moustaid-Moussa N. Protective effects of eicosapentaenoic acid in adipocyte-breast cancer cell cross talk. J Nutr Biochem. 2020 01; 75:108244.
    View in: PubMed
    Score: 0.007
  22. Butler-Fern?ndez KM, Ramos Z, Francis-Malav? AM, Bloom J, Dharmawardhane S, Hern?ndez E. Synthesis, Anti-Cancer and Anti-Migratory Evaluation of 3,6-Dibromocarbazole and 5-Bromoindole Derivatives. Molecules. 2019 Jul 24; 24(15).
    View in: PubMed
    Score: 0.007
  23. Al-Jawadi A, Moussa H, Ramalingam L, Dharmawardhane S, Gollahon L, Gunaratne P, Layeequr Rahman R, Moustaid-Moussa N. Protective properties of n-3 fatty acids and implications in obesity-associated breast cancer. J Nutr Biochem. 2018 03; 53:1-8.
    View in: PubMed
    Score: 0.006
  24. Cekanova M, Fernando RI, Siriwardhana N, Sukhthankar M, Parra C, Woraratphoka J, Malone C, Str?m A, Baek SJ, Wade PA, Saxton AM, Donnell RM, Pestell RG, Dharmawardhane S, Wimalasena J. BCL-2 family protein, BAD is down-regulated in breast cancer and inhibits cell invasion. Exp Cell Res. 2015 Feb 01; 331(1):1-10.
    View in: PubMed
    Score: 0.005
  25. Ramos G, Loperena Y, Ortiz G, Reyes F, Szeto A, Vera J, Velez J, Morales J, Morrero D, Castillo L, Dharmawardhane S, Melendez E, Washington AV. The addition of a pregnenolone pendant group enhances the anticancer properties of titanocene dichloride in a mcf-7 xenograft model. Anticancer Res. 2014 Apr; 34(4):1609-15.
    View in: PubMed
    Score: 0.005
  26. Martin H, Mali RS, Ma P, Chatterjee A, Ramdas B, Sims E, Munugalavadla V, Ghosh J, Mattingly RR, Visconte V, Tiu RV, Vlaar CP, Dharmawardhane S, Kapur R. Pak and Rac GTPases promote oncogenic KIT-induced neoplasms. J Clin Invest. 2013 Oct; 123(10):4449-63.
    View in: PubMed
    Score: 0.005
  27. Hern?ndez E, De La Mota-Peynado A, Dharmawardhane S, Vlaar CP. Novel inhibitors of Rac1 in metastatic breast cancer. P R Health Sci J. 2010 Dec; 29(4):348-56.
    View in: PubMed
    Score: 0.004
  28. Calabria LM, Piacente S, Kapusta I, Dharmawardhane SF, Segarra FM, Pessiki PJ, Mabry TJ. Triterpene saponins from Silphium radula. Phytochemistry. 2008 Feb; 69(4):961-72.
    View in: PubMed
    Score: 0.003
  29. Sokolov K, Nida D, Descour M, Lacy A, Levy M, Hall B, Dharmawardhane S, Ellington A, Korgel B, Richards-Kortum R. Molecular optical imaging of therapeutic targets of cancer. Adv Cancer Res. 2007; 96:299-344.
    View in: PubMed
    Score: 0.003
  30. Hsu ER, Anslyn EV, Dharmawardhane S, Alizadeh-Naderi R, Aaron JS, Sokolov KV, El-Naggar AK, Gillenwater AM, Richards-Kortum RR. A far-red fluorescent contrast agent to image epidermal growth factor receptor expression. Photochem Photobiol. 2004 Mar; 79(3):272-9.
    View in: PubMed
    Score: 0.002
  31. Brownson DM, Azios NG, Fuqua BK, Dharmawardhane SF, Mabry TJ. Flavonoid effects relevant to cancer. J Nutr. 2002 11; 132(11 Suppl):3482S-3489S.
    View in: PubMed
    Score: 0.002
  32. Lacy AA, Collier T, Price JE, Dharmawardhane S, Richards-Kortum R. Near real-time in vivo confocal imaging of mouse mammary tumors. Front Biosci. 2002 Jan 01; 7:f1-7.
    View in: PubMed
    Score: 0.002
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
RCMI CC is supported by the National Institute on Minority Health and Health Disparities, National Institutes of Health (NIH), through Grant Number U24MD015970. The contents of this site are solely the responsibility of the authors and do not necessarily represent the official views of the NIH

For technical support please contact support