Robert A. Nichols to Animals
This is a "connection" page, showing publications Robert A. Nichols has written about Animals.
Connection Strength
0.975
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Lantz MJ, Roberts AM, Delgado DD, Nichols RA. The neuroprotective N-terminal amyloid-? core hexapeptide reverses reactive gliosis and gliotoxicity in Alzheimer's disease pathology models. J Neuroinflammation. 2023 May 27; 20(1):129.
Score: 0.073
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Arora K, Belcaid M, Lantz MJ, Taketa R, Nichols RA. Transcriptome Profile of Nicotinic Receptor-Linked Sensitization of Beta Amyloid Neurotoxicity. Sci Rep. 2020 03 30; 10(1):5696.
Score: 0.059
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Forest KH, Nichols RA. Assessing Neuroprotective Agents for A?-Induced Neurotoxicity. Trends Mol Med. 2019 08; 25(8):685-695.
Score: 0.056
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Kabbani N, Nichols RA. Beyond the Channel: Metabotropic Signaling by Nicotinic Receptors. Trends Pharmacol Sci. 2018 04; 39(4):354-366.
Score: 0.051
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Forest KH, Alfulaij N, Arora K, Taketa R, Sherrin T, Todorovic C, Lawrence JLM, Yoshikawa GT, Ng HL, Hruby VJ, Nichols RA. Protection against ?-amyloid neurotoxicity by a non-toxic endogenous N-terminal ?-amyloid fragment and its active hexapeptide core sequence. J Neurochem. 2018 01; 144(2):201-217.
Score: 0.050
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Nichols RG, Hume NE, Smith PB, Peters JM, Patterson AD. Omics Approaches To Probe Microbiota and Drug Metabolism Interactions. Chem Res Toxicol. 2016 12 19; 29(12):1987-1997.
Score: 0.046
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Arora K, Cheng J, Nichols RA. Nicotinic Acetylcholine Receptors Sensitize a MAPK-linked Toxicity Pathway on Prolonged Exposure to ?-Amyloid. J Biol Chem. 2015 Aug 28; 290(35):21409-20.
Score: 0.042
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Lawrence JL, Tong M, Alfulaij N, Sherrin T, Contarino M, White MM, Bellinger FP, Todorovic C, Nichols RA. Regulation of presynaptic Ca2+, synaptic plasticity and contextual fear conditioning by a N-terminal ?-amyloid fragment. J Neurosci. 2014 Oct 22; 34(43):14210-8.
Score: 0.040
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Arora K, Alfulaij N, Higa JK, Panee J, Nichols RA. Impact of sustained exposure to ?-amyloid on calcium homeostasis and neuronal integrity in model nerve cell system expressing a4?2 nicotinic acetylcholine receptors. J Biol Chem. 2013 Apr 19; 288(16):11175-90.
Score: 0.036
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Nichols RA. Serotonin, presynaptic 5-HT3 receptors and synaptic plasticity in the developing cerebellum. J Physiol. 2011 Nov 01; 589(Pt 21):5019-20.
Score: 0.033
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Tong M, Arora K, White MM, Nichols RA. Role of key aromatic residues in the ligand-binding domain of alpha7 nicotinic receptors in the agonist action of beta-amyloid. J Biol Chem. 2011 Sep 30; 286(39):34373-81.
Score: 0.032
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Khan GM, Tong M, Jhun M, Arora K, Nichols RA. beta-Amyloid activates presynaptic alpha7 nicotinic acetylcholine receptors reconstituted into a model nerve cell system: involvement of lipid rafts. Eur J Neurosci. 2010 Mar; 31(5):788-96.
Score: 0.029
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Dougherty JJ, Nichols RA. Cross-regulation between colocalized nicotinic acetylcholine and 5-HT3 serotonin receptors on presynaptic nerve terminals. Acta Pharmacol Sin. 2009 Jun; 30(6):788-94.
Score: 0.028
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Mehta TK, Dougherty JJ, Wu J, Choi CH, Khan GM, Nichols RA. Defining pre-synaptic nicotinic receptors regulated by beta amyloid in mouse cortex and hippocampus with receptor null mutants. J Neurochem. 2009 Jun; 109(5):1452-8.
Score: 0.027
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Dougherty JJ, Wu J, Mehta TK, Brown B, Nichols RA. Chronic nicotine alters nicotinic receptor-induced presynaptic Ca2+ responses in isolated nerve terminals. Neurochem Res. 2008 Jun; 33(6):1106-12.
Score: 0.025
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Nichols RA, Dengler AF, Nakagawa EM, Bashkin M, Paul BT, Wu J, Khan GM. A constitutive, transient receptor potential-like Ca2+ influx pathway in presynaptic nerve endings independent of voltage-gated Ca2+ channels and Na+/Ca2+ exchange. J Biol Chem. 2007 Dec 07; 282(49):36102-11.
Score: 0.025
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Wu J, Khan GM, Nichols RA. Dopamine release in prefrontal cortex in response to beta-amyloid activation of alpha7 * nicotinic receptors. Brain Res. 2007 Nov 28; 1182:82-9.
Score: 0.025
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Wu J, Dougherty JJ, Nichols RA. Dopamine receptor regulation of Ca2+ levels in individual isolated nerve terminals from rat striatum: comparison of presynaptic D1-like and D2-like receptors. J Neurochem. 2006 Jul; 98(2):481-94.
Score: 0.023
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Dougherty JJ, Wu J, Nichols RA. Beta-amyloid regulation of presynaptic nicotinic receptors in rat hippocampus and neocortex. J Neurosci. 2003 Jul 30; 23(17):6740-7.
Score: 0.018
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Xu M, Lantz MJ, Nichols RA, Li QX. Anti-Neuroinflammatory Effects of a Semi-Synthetic Isoorientin-Based Glycogen Synthase Kinase-3? Inhibitor in Lipopolysaccharide-Activated Microglial Cells. ACS Chem Neurosci. 2022 01 05; 13(1):43-52.
Score: 0.017
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Liu Q, Zhang L, Allman EL, Hubbard TD, Murray IA, Hao F, Tian Y, Gui W, Nichols RG, Smith PB, Anitha M, Perdew GH, Patterson AD. The aryl hydrocarbon receptor activates ceramide biosynthesis in mice contributing to hepatic lipogenesis. Toxicology. 2021 06 30; 458:152831.
Score: 0.016
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Cai C, Li C, Sun R, Zhang B, Nichols RL, Hake KD, Pan X. Small RNA and degradome deep sequencing reveals important roles of microRNAs in cotton (Gossypium hirsutum L.) response to root-knot nematode Meloidogyne incognita infection. Genomics. 2021 05; 113(3):1146-1156.
Score: 0.016
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Nayak SV, Dougherty JJ, McIntosh JM, Nichols RA. Ca(2+) changes induced by different presynaptic nicotinic receptors in separate populations of individual striatal nerve terminals. J Neurochem. 2001 Mar; 76(6):1860-70.
Score: 0.016
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Roberts JP, Stokoe SA, Sathler MF, Nichols RA, Kim S. Selective coactivation of a7- and a4?2-nicotinic acetylcholine receptors reverses beta-amyloid-induced synaptic dysfunction. J Biol Chem. 2021 Jan-Jun; 296:100402.
Score: 0.016
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Rond? P, Nichols RA. Postsynaptic target regulates functional responses induced by 5-HT3 serotonin receptors on axonal varicosities of NG108-15 hybrid neuroblastoma cells. Neuroscience. 2001; 102(4):979-87.
Score: 0.015
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Rond? P, Dougherty JJ, Nichols RA. Functional IP3- and ryanodine-sensitive calcium stores in presynaptic varicosities of NG108-15 (rodent neuroblastoma x glioma hybrid) cells. J Physiol. 2000 Dec 01; 529 Pt 2:307-19.
Score: 0.015
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Tan X, Liang Z, Li Y, Zhi Y, Yi L, Bai S, Forest KH, Nichols RA, Dong Y, Li QX. Isoorientin, a GSK-3? inhibitor, rescues synaptic dysfunction, spatial memory deficits and attenuates pathological progression in APP/PS1 model mice. Behav Brain Res. 2021 02 01; 398:112968.
Score: 0.015
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Nayak SV, Rond? P, Spier AD, Lummis SC, Nichols RA. Nicotinic receptors co-localize with 5-HT(3) serotonin receptors on striatal nerve terminals. Neuropharmacology. 2000 Oct; 39(13):2681-90.
Score: 0.015
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Zhang L, Rimal B, Nichols RG, Tian Y, Smith PB, Hatzakis E, Chang SC, Butenhoff JL, Peters JM, Patterson AD. Perfluorooctane sulfonate alters gut microbiota-host metabolic homeostasis in mice. Toxicology. 2020 02 15; 431:152365.
Score: 0.014
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Tian Y, Cai J, Gui W, Nichols RG, Koo I, Zhang J, Anitha M, Patterson AD. Berberine Directly Affects the Gut Microbiota to Promote Intestinal Farnesoid X Receptor Activation. Drug Metab Dispos. 2019 02; 47(2):86-93.
Score: 0.013
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Pathak P, Xie C, Nichols RG, Ferrell JM, Boehme S, Krausz KW, Patterson AD, Gonzalez FJ, Chiang JYL. Intestine farnesoid X receptor agonist and the gut microbiota activate G-protein bile acid receptor-1 signaling to improve metabolism. Hepatology. 2018 10; 68(4):1574-1588.
Score: 0.013
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Morel C, Sherrin T, Kennedy NJ, Forest KH, Avcioglu Barutcu S, Robles M, Carpenter-Hyland E, Alfulaij N, Standen CL, Nichols RA, Benveniste M, Davis RJ, Todorovic C. JIP1-Mediated JNK Activation Negatively Regulates Synaptic Plasticity and Spatial Memory. J Neurosci. 2018 04 11; 38(15):3708-3728.
Score: 0.013
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Tian Y, Nichols RG, Cai J, Patterson AD, Cantorna MT. Vitamin A deficiency in mice alters host and gut microbial metabolism leading to altered energy homeostasis. J Nutr Biochem. 2018 04; 54:28-34.
Score: 0.012
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Zhang L, Hatzakis E, Nichols RG, Hao R, Correll J, Smith PB, Chiaro CR, Perdew GH, Patterson AD. Metabolomics Reveals that Aryl Hydrocarbon Receptor Activation by Environmental Chemicals Induces Systemic Metabolic Dysfunction in Mice. Environ Sci Technol. 2015 Jul 07; 49(13):8067-77.
Score: 0.011
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Zhang L, Nichols RG, Correll J, Murray IA, Tanaka N, Smith PB, Hubbard TD, Sebastian A, Albert I, Hatzakis E, Gonzalez FJ, Perdew GH, Patterson AD. Persistent Organic Pollutants Modify Gut Microbiota-Host Metabolic Homeostasis in Mice Through Aryl Hydrocarbon Receptor Activation. Environ Health Perspect. 2015 Jul; 123(7):679-88.
Score: 0.010
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Jiang C, Xie C, Li F, Zhang L, Nichols RG, Krausz KW, Cai J, Qi Y, Fang ZZ, Takahashi S, Tanaka N, Desai D, Amin SG, Albert I, Patterson AD, Gonzalez FJ. Intestinal farnesoid X receptor signaling promotes nonalcoholic fatty liver disease. J Clin Invest. 2015 Jan; 125(1):386-402.
Score: 0.010
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Pitts MW, Raman AV, Hashimoto AC, Todorovic C, Nichols RA, Berry MJ. Deletion of selenoprotein P results in impaired function of parvalbumin interneurons and alterations in fear learning and sensorimotor gating. Neuroscience. 2012 Apr 19; 208:58-68.
Score: 0.008
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Yang K, Buhlman L, Khan GM, Nichols RA, Jin G, McIntosh JM, Whiteaker P, Lukas RJ, Wu J. Functional nicotinic acetylcholine receptors containing a6 subunits are on GABAergic neuronal boutons adherent to ventral tegmental area dopamine neurons. J Neurosci. 2011 Feb 16; 31(7):2537-48.
Score: 0.008
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van Hooft JA, Dougherty JJ, Endeman D, Nichols RA, Wadman WJ. Gabapentin inhibits presynaptic Ca(2+) influx and synaptic transmission in rat hippocampus and neocortex. Eur J Pharmacol. 2002 Aug 09; 449(3):221-28.
Score: 0.004