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Connection

David A. Foster to Humans

This is a "connection" page, showing publications David A. Foster has written about Humans.
Connection Strength

1.016
  1. Frias MA, Hatipoglu A, Foster DA. Regulation of mTOR by phosphatidic acid. Trends Endocrinol Metab. 2023 03; 34(3):170-180.
    View in: PubMed
    Score: 0.041
  2. Hatipoglu A, Menon D, Levy T, Frias MA, Foster DA. Inhibiting glutamine utilization creates a synthetic lethality for suppression of ATP citrate lyase in KRas-driven cancer cells. PLoS One. 2022; 17(10):e0276579.
    View in: PubMed
    Score: 0.041
  3. Chakraborty S, Utter MB, Frias MA, Foster DA. Cancer cells with defective RB and CDKN2A are resistant to the apoptotic effects of rapamycin. Cancer Lett. 2021 12 01; 522:164-170.
    View in: PubMed
    Score: 0.038
  4. Uddin S, Melnyk N, Foster DA. Albumin promotes the progression of fibroblasts through late G1 into S-phase in the absence of growth factors. Cell Cycle. 2020 09; 19(17):2158-2167.
    View in: PubMed
    Score: 0.035
  5. Frias MA, Mukhopadhyay S, Lehman E, Walasek A, Utter M, Menon D, Foster DA. Phosphatidic acid drives mTORC1 lysosomal translocation in the absence of amino acids. J Biol Chem. 2020 01 03; 295(1):263-274.
    View in: PubMed
    Score: 0.033
  6. Bernfeld E, Foster DA. Glutamine as an Essential Amino Acid for KRas-Driven Cancer Cells. Trends Endocrinol Metab. 2019 06; 30(6):357-368.
    View in: PubMed
    Score: 0.032
  7. Bernfeld E, Menon D, Vaghela V, Zerin I, Faruque P, Frias MA, Foster DA. Phospholipase D-dependent mTOR complex 1 (mTORC1) activation by glutamine. J Biol Chem. 2018 10 19; 293(42):16390-16401.
    View in: PubMed
    Score: 0.031
  8. Utter M, Chakraborty S, Goren L, Feuser L, Zhu YS, Foster DA. Elevated phospholipase D activity in androgen-insensitive prostate cancer cells promotes both survival and metastatic phenotypes. Cancer Lett. 2018 06 01; 423:28-35.
    View in: PubMed
    Score: 0.029
  9. Menon D, Salloum D, Bernfeld E, Gorodetsky E, Akselrod A, Frias MA, Sudderth J, Chen PH, DeBerardinis R, Foster DA. Lipid sensing by mTOR complexes via de novo synthesis of phosphatidic acid. J Biol Chem. 2017 04 14; 292(15):6303-6311.
    View in: PubMed
    Score: 0.027
  10. Patel D, Salloum D, Saqcena M, Chatterjee A, Mroz V, Ohh M, Foster DA. A Late G1 Lipid Checkpoint That Is Dysregulated in Clear Cell Renal Carcinoma Cells. J Biol Chem. 2017 01 20; 292(3):936-944.
    View in: PubMed
    Score: 0.027
  11. Patel D, Menon D, Bernfeld E, Mroz V, Kalan S, Loayza D, Foster DA. Aspartate Rescues S-phase Arrest Caused by Suppression of Glutamine Utilization in KRas-driven Cancer Cells. J Biol Chem. 2016 Apr 22; 291(17):9322-9.
    View in: PubMed
    Score: 0.026
  12. Mukhopadhyay S, Frias MA, Chatterjee A, Yellen P, Foster DA. The Enigma of Rapamycin Dosage. Mol Cancer Ther. 2016 Mar; 15(3):347-53.
    View in: PubMed
    Score: 0.026
  13. Saqcena M, Patel D, Menon D, Mukhopadhyay S, Foster DA. Apoptotic effects of high-dose rapamycin occur in S-phase of the cell cycle. Cell Cycle. 2015; 14(14):2285-92.
    View in: PubMed
    Score: 0.024
  14. Chatterjee A, Mukhopadhyay S, Tung K, Patel D, Foster DA. Rapamycin-induced G1 cell cycle arrest employs both TGF-? and Rb pathways. Cancer Lett. 2015 May 01; 360(2):134-40.
    View in: PubMed
    Score: 0.024
  15. Mukhopadhyay S, Saqcena M, Chatterjee A, Garcia A, Frias MA, Foster DA. Reciprocal regulation of AMP-activated protein kinase and phospholipase D. J Biol Chem. 2015 Mar 13; 290(11):6986-93.
    View in: PubMed
    Score: 0.024
  16. Mukhopadhyay S, Chatterjee A, Kogan D, Patel D, Foster DA. 5-Aminoimidazole-4-carboxamide-1-?-4-ribofuranoside (AICAR) enhances the efficacy of rapamycin in human cancer cells. Cell Cycle. 2015; 14(20):3331-9.
    View in: PubMed
    Score: 0.024
  17. Yellen P, Foster DA. Inhibition of fatty acid synthase induces pro-survival Akt and ERK signaling in K-Ras-driven cancer cells. Cancer Lett. 2014 Oct 28; 353(2):258-63.
    View in: PubMed
    Score: 0.023
  18. Foster DA, Salloum D, Menon D, Frias MA. Phospholipase D and the maintenance of phosphatidic acid levels for regulation of mammalian target of rapamycin (mTOR). J Biol Chem. 2014 Aug 15; 289(33):22583-22588.
    View in: PubMed
    Score: 0.023
  19. Salloum D, Mukhopadhyay S, Tung K, Polonetskaya A, Foster DA. Mutant ras elevates dependence on serum lipids and creates a synthetic lethality for rapamycin. Mol Cancer Ther. 2014 Mar; 13(3):733-41.
    View in: PubMed
    Score: 0.022
  20. Saqcena M, Menon D, Patel D, Mukhopadhyay S, Chow V, Foster DA. Amino acids and mTOR mediate distinct metabolic checkpoints in mammalian G1 cell cycle. PLoS One. 2013; 8(8):e74157.
    View in: PubMed
    Score: 0.021
  21. Foster DA. Phosphatidic acid and lipid-sensing by mTOR. Trends Endocrinol Metab. 2013 Jun; 24(6):272-8.
    View in: PubMed
    Score: 0.021
  22. Le Gendre O, Sookdeo A, Duliepre SA, Utter M, Frias M, Foster DA. Suppression of AKT phosphorylation restores rapamycin-based synthetic lethality in SMAD4-defective pancreatic cancer cells. Mol Cancer Res. 2013 May; 11(5):474-81.
    View in: PubMed
    Score: 0.021
  23. Yellen P, Chatterjee A, Preda A, Foster DA. Inhibition of S6 kinase suppresses the apoptotic effect of eIF4E ablation by inducing TGF-?-dependent G1 cell cycle arrest. Cancer Lett. 2013 Jun 10; 333(2):239-43.
    View in: PubMed
    Score: 0.021
  24. Yellen P, Saqcena M, Salloum D, Feng J, Preda A, Xu L, Rodrik-Outmezguine V, Foster DA. High-dose rapamycin induces apoptosis in human cancer cells by dissociating mTOR complex 1 and suppressing phosphorylation of 4E-BP1. Cell Cycle. 2011 Nov 15; 10(22):3948-56.
    View in: PubMed
    Score: 0.019
  25. Xu L, Salloum D, Medlin PS, Saqcena M, Yellen P, Perrella B, Foster DA. Phospholipase D mediates nutrient input to mammalian target of rapamycin complex 1 (mTORC1). J Biol Chem. 2011 Jul 22; 286(29):25477-86.
    View in: PubMed
    Score: 0.018
  26. Toschi A, Lee E, Thompson S, Gadir N, Yellen P, Drain CM, Ohh M, Foster DA. Phospholipase D-mTOR requirement for the Warburg effect in human cancer cells. Cancer Lett. 2010 Dec 18; 299(1):72-9.
    View in: PubMed
    Score: 0.018
  27. Lyo D, Xu L, Foster DA. Phospholipase D stabilizes HDM2 through an mTORC2/SGK1 pathway. Biochem Biophys Res Commun. 2010 May 28; 396(2):562-5.
    View in: PubMed
    Score: 0.017
  28. Foster DA. Reduced mortality and moderate alcohol consumption: the phospholipase D-mTOR connection. Cell Cycle. 2010 Apr 01; 9(7):1291-4.
    View in: PubMed
    Score: 0.017
  29. Foster DA, Toschi A. Targeting mTOR with rapamycin: one dose does not fit all. Cell Cycle. 2009 Apr 01; 8(7):1026-9.
    View in: PubMed
    Score: 0.016
  30. Foster DA. Phosphatidic acid signaling to mTOR: signals for the survival of human cancer cells. Biochim Biophys Acta. 2009 Sep; 1791(9):949-55.
    View in: PubMed
    Score: 0.016
  31. Toschi A, Lee E, Xu L, Garcia A, Gadir N, Foster DA. Regulation of mTORC1 and mTORC2 complex assembly by phosphatidic acid: competition with rapamycin. Mol Cell Biol. 2009 Mar; 29(6):1411-20.
    View in: PubMed
    Score: 0.016
  32. Toschi A, Lee E, Gadir N, Ohh M, Foster DA. Differential dependence of hypoxia-inducible factors 1 alpha and 2 alpha on mTORC1 and mTORC2. J Biol Chem. 2008 Dec 12; 283(50):34495-9.
    View in: PubMed
    Score: 0.015
  33. Foster DA, Gadir N. [Can defective TGF-Beta signaling be an Achilles heel in human cancer?]. Ai Zheng. 2008 Aug; 27(8):882-4.
    View in: PubMed
    Score: 0.015
  34. Bonis PA, Pickens GT, Rind DM, Foster DA. Association of a clinical knowledge support system with improved patient safety, reduced complications and shorter length of stay among Medicare beneficiaries in acute care hospitals in the United States. Int J Med Inform. 2008 Nov; 77(11):745-53.
    View in: PubMed
    Score: 0.015
  35. Shi M, Zheng Y, Garcia A, Xu L, Foster DA. Phospholipase D provides a survival signal in human cancer cells with activated H-Ras or K-Ras. Cancer Lett. 2007 Dec 18; 258(2):268-75.
    View in: PubMed
    Score: 0.014
  36. Gadir N, Lee E, Garcia A, Toschi A, Foster DA. Suppression of TGF-beta signaling by phospholipase D. Cell Cycle. 2007 Nov 15; 6(22):2840-5.
    View in: PubMed
    Score: 0.014
  37. Foster DA. Regulation of mTOR by phosphatidic acid? Cancer Res. 2007 Jan 01; 67(1):1-4.
    View in: PubMed
    Score: 0.014
  38. Rodrik V, Gomes E, Hui L, Rockwell P, Foster DA. Myc stabilization in response to estrogen and phospholipase D in MCF-7 breast cancer cells. FEBS Lett. 2006 Oct 16; 580(24):5647-52.
    View in: PubMed
    Score: 0.013
  39. Zheng Y, Rodrik V, Toschi A, Shi M, Hui L, Shen Y, Foster DA. Phospholipase D couples survival and migration signals in stress response of human cancer cells. J Biol Chem. 2006 Jun 09; 281(23):15862-8.
    View in: PubMed
    Score: 0.013
  40. Rodrik V, Zheng Y, Harrow F, Chen Y, Foster DA. Survival signals generated by estrogen and phospholipase D in MCF-7 breast cancer cells are dependent on Myc. Mol Cell Biol. 2005 Sep; 25(17):7917-25.
    View in: PubMed
    Score: 0.012
  41. Hui L, Rodrik V, Pielak RM, Knirr S, Zheng Y, Foster DA. mTOR-dependent suppression of protein phosphatase 2A is critical for phospholipase D survival signals in human breast cancer cells. J Biol Chem. 2005 Oct 28; 280(43):35829-35.
    View in: PubMed
    Score: 0.012
  42. Chen Y, Rodrik V, Foster DA. Alternative phospholipase D/mTOR survival signal in human breast cancer cells. Oncogene. 2005 Jan 20; 24(4):672-9.
    View in: PubMed
    Score: 0.012
  43. Foster DA. Targeting mTOR-mediated survival signals in anticancer therapeutic strategies. Expert Rev Anticancer Ther. 2004 Aug; 4(4):691-701.
    View in: PubMed
    Score: 0.011
  44. Jackson DN, Foster DA. The enigmatic protein kinase Cdelta: complex roles in cell proliferation and survival. FASEB J. 2004 Apr; 18(6):627-36.
    View in: PubMed
    Score: 0.011
  45. Foster DA, Xu L. Phospholipase D in cell proliferation and cancer. Mol Cancer Res. 2003 Sep; 1(11):789-800.
    View in: PubMed
    Score: 0.011
  46. Chen Y, Zheng Y, Foster DA. Phospholipase D confers rapamycin resistance in human breast cancer cells. Oncogene. 2003 Jun 19; 22(25):3937-42.
    View in: PubMed
    Score: 0.011
  47. Zhong M, Shen Y, Zheng Y, Joseph T, Jackson D, Foster DA. Phospholipase D prevents apoptosis in v-Src-transformed rat fibroblasts and MDA-MB-231 breast cancer cells. Biochem Biophys Res Commun. 2003 Mar 14; 302(3):615-9.
    View in: PubMed
    Score: 0.010
  48. Shen Y, Zheng Y, Foster DA. Phospholipase D2 stimulates cell protrusion in v-Src-transformed cells. Biochem Biophys Res Commun. 2002 Apr 26; 293(1):201-6.
    View in: PubMed
    Score: 0.010
  49. Jiang Y, Lu Z, Zang Q, Foster DA. Regulation of phosphatidic acid phosphohydrolase by epidermal growth factor. Reduced association with the EGF receptor followed by increased association with protein kinase Cepsilon. J Biol Chem. 1996 Nov 22; 271(47):29529-32.
    View in: PubMed
    Score: 0.007
  50. Einbond LS, Mighty J, Kashiwazaki R, Figueroa M, Jalees F, Acuna UM, Le Gendre O, Foster DA, Kennelly EJ. Garcinia benzophenones inhibit the growth of human colon cancer cells and synergize with sulindac sulfide and turmeric. Anticancer Agents Med Chem. 2013 Dec; 13(10):1540-50.
    View in: PubMed
    Score: 0.005
  51. Roberts AM, Watson IR, Evans AJ, Foster DA, Irwin MS, Ohh M. Suppression of hypoxia-inducible factor 2alpha restores p53 activity via Hdm2 and reverses chemoresistance of renal carcinoma cells. Cancer Res. 2009 Dec 01; 69(23):9056-64.
    View in: PubMed
    Score: 0.004
  52. Garcia A, Zheng Y, Zhao C, Toschi A, Fan J, Shraibman N, Brown HA, Bar-Sagi D, Foster DA, Arbiser JL. Honokiol suppresses survival signals mediated by Ras-dependent phospholipase D activity in human cancer cells. Clin Cancer Res. 2008 Jul 01; 14(13):4267-74.
    View in: PubMed
    Score: 0.004
  53. Mor A, Campi G, Du G, Zheng Y, Foster DA, Dustin ML, Philips MR. The lymphocyte function-associated antigen-1 receptor costimulates plasma membrane Ras via phospholipase D2. Nat Cell Biol. 2007 Jun; 9(6):713-9.
    View in: PubMed
    Score: 0.003
  54. Cai D, Netzer WJ, Zhong M, Lin Y, Du G, Frohman M, Foster DA, Sisodia SS, Xu H, Gorelick FS, Greengard P. Presenilin-1 uses phospholipase D1 as a negative regulator of beta-amyloid formation. Proc Natl Acad Sci U S A. 2006 Feb 07; 103(6):1941-6.
    View in: PubMed
    Score: 0.003
  55. Chen X, Hui L, Foster DA, Drain CM. Efficient synthesis and photodynamic activity of porphyrin-saccharide conjugates: targeting and incapacitating cancer cells. Biochemistry. 2004 Aug 31; 43(34):10918-29.
    View in: PubMed
    Score: 0.003
  56. Abbas T, White D, Hui L, Yoshida K, Foster DA, Bargonetti J. Inhibition of human p53 basal transcription by down-regulation of protein kinase Cdelta. J Biol Chem. 2004 Mar 12; 279(11):9970-7.
    View in: PubMed
    Score: 0.003
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
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