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Connection

Zhigang Xiong to Neurons

This is a "connection" page, showing publications Zhigang Xiong has written about Neurons.
Connection Strength

4.654
  1. Zhou R, Leng T, Yang T, Chen F, Hu W, Xiong ZG. ?-Estradiol Protects Against Acidosis-Mediated and Ischemic Neuronal Injury by Promoting ASIC1a (Acid-Sensing Ion Channel 1a) Protein Degradation. Stroke. 2019 10; 50(10):2902-2911.
    View in: PubMed
    Score: 0.424
  2. Huang Y, Leng TD, Inoue K, Yang T, Liu M, Horgen FD, Fleig A, Li J, Xiong ZG. TRPM7 channels play a role in high glucose-induced endoplasmic reticulum stress and neuronal cell apoptosis. J Biol Chem. 2018 09 14; 293(37):14393-14406.
    View in: PubMed
    Score: 0.395
  3. O'Bryant Z, Leng T, Liu M, Inoue K, Vann KT, Xiong ZG. Acid Sensing Ion Channels (ASICs) in NS20Y cells - potential role in neuronal differentiation. Mol Brain. 2016 06 24; 9(1):68.
    View in: PubMed
    Score: 0.341
  4. Chu XP, Xiong ZG. Physiological and pathological functions of acid-sensing ion channels in the central nervous system. Curr Drug Targets. 2012 Feb; 13(2):263-71.
    View in: PubMed
    Score: 0.252
  5. Lin J, Chu X, Maysami S, Li M, Si H, Cottrell JE, Simon RP, Xiong Z. Inhibition of acid sensing ion channel currents by lidocaine in cultured mouse cortical neurons. Anesth Analg. 2011 Apr; 112(4):977-81.
    View in: PubMed
    Score: 0.236
  6. Li M, Kratzer E, Inoue K, Simon RP, Xiong ZG. Developmental change in the electrophysiological and pharmacological properties of acid-sensing ion channels in CNS neurons. J Physiol. 2010 Oct 15; 588(Pt 20):3883-900.
    View in: PubMed
    Score: 0.228
  7. Li M, Inoue K, Branigan D, Kratzer E, Hansen JC, Chen JW, Simon RP, Xiong ZG. Acid-sensing ion channels in acidosis-induced injury of human brain neurons. J Cereb Blood Flow Metab. 2010 Jun; 30(6):1247-60.
    View in: PubMed
    Score: 0.221
  8. Inoue K, Branigan D, Xiong ZG. Zinc-induced neurotoxicity mediated by transient receptor potential melastatin 7 channels. J Biol Chem. 2010 Mar 05; 285(10):7430-9.
    View in: PubMed
    Score: 0.218
  9. Xu TL, Xiong ZG. Dynamic regulation of acid-sensing ion channels by extracellular and intracellular modulators. Curr Med Chem. 2007; 14(16):1753-63.
    View in: PubMed
    Score: 0.177
  10. Wang WZ, Chu XP, Li MH, Seeds J, Simon RP, Xiong ZG. Modulation of acid-sensing ion channel currents, acid-induced increase of intracellular Ca2+, and acidosis-mediated neuronal injury by intracellular pH. J Biol Chem. 2006 Sep 29; 281(39):29369-78.
    View in: PubMed
    Score: 0.172
  11. Chu XP, Close N, Saugstad JA, Xiong ZG. ASIC1a-specific modulation of acid-sensing ion channels in mouse cortical neurons by redox reagents. J Neurosci. 2006 May 17; 26(20):5329-39.
    View in: PubMed
    Score: 0.169
  12. Chu XP, Wemmie JA, Wang WZ, Zhu XM, Saugstad JA, Price MP, Simon RP, Xiong ZG. Subunit-dependent high-affinity zinc inhibition of acid-sensing ion channels. J Neurosci. 2004 Oct 06; 24(40):8678-89.
    View in: PubMed
    Score: 0.152
  13. Chu XP, Zhu XM, Wei WL, Li GH, Simon RP, MacDonald JF, Xiong ZG. Acidosis decreases low Ca(2+)-induced neuronal excitation by inhibiting the activity of calcium-sensing cation channels in cultured mouse hippocampal neurons. J Physiol. 2003 Jul 15; 550(Pt 2):385-99.
    View in: PubMed
    Score: 0.138
  14. Wang T, Zhou G, He M, Xu Y, Rusyniak WG, Xu Y, Ji Y, Simon RP, Xiong ZG, Zha XM. GPR68 Is a Neuroprotective Proton Receptor in Brain Ischemia. Stroke. 2020 12; 51(12):3690-3700.
    View in: PubMed
    Score: 0.115
  15. Zhang L, Leng TD, Yang T, Li J, Xiong ZG. Protein Kinase C Regulates ASIC1a Protein Expression and Channel Function via NF-kB Signaling Pathway. Mol Neurobiol. 2020 Nov; 57(11):4754-4766.
    View in: PubMed
    Score: 0.114
  16. Zhou RP, Leng TD, Yang T, Chen FH, Xiong ZG. Acute Ethanol Exposure Promotes Autophagy-Lysosome Pathway-Dependent ASIC1a Protein Degradation and Protects Against Acidosis-Induced Neurotoxicity. Mol Neurobiol. 2019 May; 56(5):3326-3340.
    View in: PubMed
    Score: 0.099
  17. Jiang N, Wu J, Leng T, Yang T, Zhou Y, Jiang Q, Wang B, Hu Y, Ji YH, Simon RP, Chu XP, Xiong ZG, Zha XM. Region specific contribution of ASIC2 to acidosis-and ischemia-induced neuronal injury. J Cereb Blood Flow Metab. 2017 Feb; 37(2):528-540.
    View in: PubMed
    Score: 0.086
  18. Leng TD, Si HF, Li J, Yang T, Zhu M, Wang B, Simon RP, Xiong ZG. Amiloride Analogs as ASIC1a Inhibitors. CNS Neurosci Ther. 2016 06; 22(6):468-76.
    View in: PubMed
    Score: 0.083
  19. Wang YZ, Wang JJ, Huang Y, Liu F, Zeng WZ, Li Y, Xiong ZG, Zhu MX, Xu TL. Tissue acidosis induces neuronal necroptosis via ASIC1a channel independent of its ionic conduction. Elife. 2015 Nov 02; 4.
    View in: PubMed
    Score: 0.082
  20. Huang Y, Jiang N, Li J, Ji YH, Xiong ZG, Zha XM. Two aspects of ASIC function: Synaptic plasticity and neuronal injury. Neuropharmacology. 2015 Jul; 94:42-8.
    View in: PubMed
    Score: 0.077
  21. Leng TD, Lin J, Sun HW, Zeng Z, O'Bryant Z, Inoue K, Xiong ZG. Local anesthetic lidocaine inhibits TRPM7 current and TRPM7-mediated zinc toxicity. CNS Neurosci Ther. 2015 Jan; 21(1):32-9.
    View in: PubMed
    Score: 0.075
  22. Leng T, Lin J, Cottrell JE, Xiong ZG. Subunit and frequency-dependent inhibition of acid sensing ion channels by local anesthetic tetracaine. Mol Pain. 2013 Jun 10; 9:27.
    View in: PubMed
    Score: 0.069
  23. Li MH, Inoue K, Si HF, Xiong ZG. Calcium-permeable ion channels involved in glutamate receptor-independent ischemic brain injury. Acta Pharmacol Sin. 2011 Jun; 32(6):734-40.
    View in: PubMed
    Score: 0.060
  24. Duan B, Wang YZ, Yang T, Chu XP, Yu Y, Huang Y, Cao H, Hansen J, Simon RP, Zhu MX, Xiong ZG, Xu TL. Extracellular spermine exacerbates ischemic neuronal injury through sensitization of ASIC1a channels to extracellular acidosis. J Neurosci. 2011 Feb 09; 31(6):2101-12.
    View in: PubMed
    Score: 0.059
  25. Coombes E, Jiang J, Chu XP, Inoue K, Seeds J, Branigan D, Simon RP, Xiong ZG. Pathophysiologically relevant levels of hydrogen peroxide induce glutamate-independent neurodegeneration that involves activation of transient receptor potential melastatin 7 channels. Antioxid Redox Signal. 2011 May 15; 14(10):1815-27.
    View in: PubMed
    Score: 0.059
  26. Chai S, Li M, Branigan D, Xiong ZG, Simon RP. Activation of acid-sensing ion channel 1a (ASIC1a) by surface trafficking. J Biol Chem. 2010 Apr 23; 285(17):13002-11.
    View in: PubMed
    Score: 0.055
  27. Jiang Q, Li MH, Papasian CJ, Branigan D, Xiong ZG, Wang JQ, Chu XP. Characterization of acid-sensing ion channels in medium spiny neurons of mouse striatum. Neuroscience. 2009 Aug 04; 162(1):55-66.
    View in: PubMed
    Score: 0.052
  28. Xiong ZG, Pignataro G, Li M, Chang SY, Simon RP. Acid-sensing ion channels (ASICs) as pharmacological targets for neurodegenerative diseases. Curr Opin Pharmacol. 2008 Feb; 8(1):25-32.
    View in: PubMed
    Score: 0.047
  29. Wei WL, Sun HS, Olah ME, Sun X, Czerwinska E, Czerwinski W, Mori Y, Orser BA, Xiong ZG, Jackson MF, Tymianski M, MacDonald JF. TRPM7 channels in hippocampal neurons detect levels of extracellular divalent cations. Proc Natl Acad Sci U S A. 2007 Oct 09; 104(41):16323-8.
    View in: PubMed
    Score: 0.047
  30. Murphy B, Dunleavy M, Shinoda S, Schindler C, Meller R, Bellver-Estelles C, Hatazaki S, Dicker P, Yamamoto A, Koegel I, Chu X, Wang W, Xiong Z, Prehn J, Simon R, Henshall D. Bcl-w protects hippocampus during experimental status epilepticus. Am J Pathol. 2007 Oct; 171(4):1258-68.
    View in: PubMed
    Score: 0.046
  31. Xiong ZG, Chu XP, Simon RP. Acid sensing ion channels--novel therapeutic targets for ischemic brain injury. Front Biosci. 2007 Jan 01; 12:1376-86.
    View in: PubMed
    Score: 0.044
  32. Xiong ZG, Chu XP, Simon RP. Ca2+ -permeable acid-sensing ion channels and ischemic brain injury. J Membr Biol. 2006 Jan; 209(1):59-68.
    View in: PubMed
    Score: 0.042
  33. Ye JH, Wang F, Krnjevic K, Wang W, Xiong ZG, Zhang J. Presynaptic glycine receptors on GABAergic terminals facilitate discharge of dopaminergic neurons in ventral tegmental area. J Neurosci. 2004 Oct 13; 24(41):8961-74.
    View in: PubMed
    Score: 0.038
  34. Chen D, Jin K, Kawaguchi K, Nakayama M, Zhou X, Xiong Z, Zhou A, Mao XO, Greenberg DA, Graham SH, Simon RP. Ero1-L, an ischemia-inducible gene from rat brain with homology to global ischemia-induced gene 11 (Giig11), is localized to neuronal dendrites by a dispersed identifier (ID) element-dependent mechanism. J Neurochem. 2003 May; 85(3):670-9.
    View in: PubMed
    Score: 0.034
  35. Wu BM, Bargaineer J, Zhang L, Yang T, Xiong ZG, Leng TD. Upregulation of acid sensing ion channel 1a (ASIC1a) by hydrogen peroxide through the JNK pathway. Acta Pharmacol Sin. 2021 Aug; 42(8):1248-1255.
    View in: PubMed
    Score: 0.029
  36. Xiao L, Chang SY, Xiong ZG, Selveraj P, Peng Loh Y. Absence of Carboxypeptidase E/Neurotrophic Factor-?1 in Knock-Out Mice Leads to Dysfunction of BDNF-TRKB Signaling in Hippocampus. J Mol Neurosci. 2017 May; 62(1):79-87.
    View in: PubMed
    Score: 0.023
  37. Leng T, Liu A, Wang Y, Chen X, Zhou S, Li Q, Zhu W, Zhou Y, Su X, Huang Y, Yin W, Qiu P, Hu H, Xiong ZG, Zhang J, Yan G. Naturally occurring marine steroid 24-methylenecholestane-3?,5a,6?,19-tetraol functions as a novel neuroprotectant. Steroids. 2016 Jan; 105:96-105.
    View in: PubMed
    Score: 0.020
  38. Liu AJ, Zang P, Guo JM, Wang W, Dong WZ, Guo W, Xiong ZG, Wang WZ, Su DF. Involvement of acetylcholine-a7nAChR in the protective effects of arterial baroreflex against ischemic stroke. CNS Neurosci Ther. 2012 Nov; 18(11):918-26.
    View in: PubMed
    Score: 0.017
  39. Chen X, Numata T, Li M, Mori Y, Orser BA, Jackson MF, Xiong ZG, MacDonald JF. The modulation of TRPM7 currents by nafamostat mesilate depends directly upon extracellular concentrations of divalent cations. Mol Brain. 2010 Dec 01; 3:38.
    View in: PubMed
    Score: 0.015
  40. Chen X, Qiu L, Li M, D?rrnagel S, Orser BA, Xiong ZG, MacDonald JF. Diarylamidines: high potency inhibitors of acid-sensing ion channels. Neuropharmacology. 2010 Jun; 58(7):1045-53.
    View in: PubMed
    Score: 0.014
  41. Meller R, Thompson SJ, Lusardi TA, Ordonez AN, Ashley MD, Jessick V, Wang W, Torrey DJ, Henshall DC, Gafken PR, Saugstad JA, Xiong ZG, Simon RP. Ubiquitin proteasome-mediated synaptic reorganization: a novel mechanism underlying rapid ischemic tolerance. J Neurosci. 2008 Jan 02; 28(1):50-9.
    View in: PubMed
    Score: 0.012
  42. Chai S, Li M, Lan J, Xiong ZG, Saugstad JA, Simon RP. A kinase-anchoring protein 150 and calcineurin are involved in regulation of acid-sensing ion channels ASIC1a and ASIC2a. J Biol Chem. 2007 Aug 03; 282(31):22668-77.
    View in: PubMed
    Score: 0.011
  43. Zhou A, Minami M, Zhu X, Bae S, Minthorne J, Lan J, Xiong ZG, Simon RP. Altered biosynthesis of neuropeptide processing enzyme carboxypeptidase E after brain ischemia: molecular mechanism and implication. J Cereb Blood Flow Metab. 2004 Jun; 24(6):612-22.
    View in: PubMed
    Score: 0.009
Connection Strength

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