George Perry to Neurons
This is a "connection" page, showing publications George Perry has written about Neurons.
Connection Strength
6.742
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Hofer T, Perry G. Nucleic acid oxidative damage in Alzheimer's disease-explained by the hepcidin-ferroportin neuronal iron overload hypothesis? J Trace Elem Med Biol. 2016 Dec; 38:1-9.
Score: 0.329
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Zhu X, Castellani RJ, Ziats NP, Petersen RB, Gon Lee H, Perry G. Mark A. Smith: neurocytochemistry innovator. J Neurochem. 2012 Mar; 120(6):1139-40.
Score: 0.243
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Nunomura A, Tamaoki T, Tanaka K, Motohashi N, Nakamura M, Hayashi T, Yamaguchi H, Shimohama S, Lee HG, Zhu X, Smith MA, Perry G. Intraneuronal amyloid beta accumulation and oxidative damage to nucleic acids in Alzheimer disease. Neurobiol Dis. 2010 Mar; 37(3):731-7.
Score: 0.210
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Nunomura A, Moreira PI, Lee HG, Zhu X, Castellani RJ, Smith MA, Perry G. Neuronal death and survival under oxidative stress in Alzheimer and Parkinson diseases. CNS Neurol Disord Drug Targets. 2007 Dec; 6(6):411-23.
Score: 0.182
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Moreira PI, Zhu X, Lee HG, Honda K, Smith MA, Perry G. The (un)balance between metabolic and oxidative abnormalities and cellular compensatory responses in Alzheimer disease. Mech Ageing Dev. 2006 Jun; 127(6):501-6.
Score: 0.162
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Moreira PI, Zhu X, Liu Q, Honda K, Siedlak SL, Harris PL, Smith MA, Perry G. Compensatory responses induced by oxidative stress in Alzheimer disease. Biol Res. 2006; 39(1):7-13.
Score: 0.160
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Nunomura A, Chiba S, Lippa CF, Cras P, Kalaria RN, Takeda A, Honda K, Smith MA, Perry G. Neuronal RNA oxidation is a prominent feature of familial Alzheimer's disease. Neurobiol Dis. 2004 Oct; 17(1):108-13.
Score: 0.146
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Ghanbari HA, Ghanbari K, Harris PL, Jones PK, Kubat Z, Castellani RJ, Wolozin BL, Smith MA, Perry G. Oxidative damage in cultured human olfactory neurons from Alzheimer's disease patients. Aging Cell. 2004 02; 3(1):41-4.
Score: 0.140
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Lee HG, Petersen RB, Zhu X, Honda K, Aliev G, Smith MA, Perry G. Will preventing protein aggregates live up to its promise as prophylaxis against neurodegenerative diseases? Brain Pathol. 2003 Oct; 13(4):630-8.
Score: 0.136
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Aliev G, Seyidova D, Lamb BT, Obrenovich ME, Siedlak SL, Vinters HV, Friedland RP, LaManna JC, Smith MA, Perry G. Mitochondria and vascular lesions as a central target for the development of Alzheimer's disease and Alzheimer disease-like pathology in transgenic mice. Neurol Res. 2003 Sep; 25(6):665-74.
Score: 0.136
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Perry G, Castellani RJ, Smith MA, Harris PL, Kubat Z, Ghanbari K, Jones PK, Cordone G, Tabaton M, Wolozin B, Ghanbari H. Oxidative damage in the olfactory system in Alzheimer's disease. Acta Neuropathol. 2003 Dec; 106(6):552-6.
Score: 0.136
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Perry G, Zhu X, Smith MA. Do neurons have a choice in death? Am J Pathol. 2001 Jan; 158(1):1-2.
Score: 0.113
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Mart?nez-Maldonado A, Ontiveros-Torres M?, Harrington CR, Montiel-Sosa JF, Prandiz RG, Bocanegra-L?pez P, Sorsby-Vargas AM, Bravo-Mu?oz M, Flor?n-Gardu?o B, Villanueva-Fierro I, Perry G, Garc?s-Ram?rez L, de la Cruz F, Mart?nez-Robles S, Pacheco-Herrero M, Luna-Mu?oz J. Molecular Processing of Tau Protein in Progressive Supranuclear Palsy: Neuronal and Glial Degeneration. J Alzheimers Dis. 2021; 79(4):1517-1531.
Score: 0.113
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Avila J, Perry G. A Multilevel View of the Development of Alzheimer's Disease. Neuroscience. 2021 03 01; 457:283-293.
Score: 0.112
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Smith MA, Rottkamp CA, Nunomura A, Raina AK, Perry G. Oxidative stress in Alzheimer's disease. Biochim Biophys Acta. 2000 Jul 26; 1502(1):139-44.
Score: 0.109
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Perry G, Nunomura A, Hirai K, Takeda A, Aliev G, Smith MA. Oxidative damage in Alzheimer's disease: the metabolic dimension. Int J Dev Neurosci. 2000 Jul-Aug; 18(4-5):417-21.
Score: 0.109
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Wang W, Zhao F, Ma X, Perry G, Zhu X. Mitochondria dysfunction in the pathogenesis of Alzheimer's disease: recent advances. Mol Neurodegener. 2020 05 29; 15(1):30.
Score: 0.108
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Perry G, Roder H, Nunomura A, Takeda A, Friedlich AL, Zhu X, Raina AK, Holbrook N, Siedlak SL, Harris PL, Smith MA. Activation of neuronal extracellular receptor kinase (ERK) in Alzheimer disease links oxidative stress to abnormal phosphorylation. Neuroreport. 1999 Aug 02; 10(11):2411-5.
Score: 0.102
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Perry G, Nunomura A, Lucassen P, Lassmann H, Smith MA. Apoptosis and Alzheimer's disease. Science. 1998 Nov 13; 282(5392):1268-9.
Score: 0.097
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Perry G, Nunomura A, Smith MA. A suicide note from Alzheimer disease neurons? Nat Med. 1998 Aug; 4(8):897-8.
Score: 0.095
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Jiang S, Nandy P, Wang W, Ma X, Hsia J, Wang C, Wang Z, Niu M, Siedlak SL, Torres S, Fujioka H, Xu Y, Lee HG, Perry G, Liu J, Zhu X. Mfn2 ablation causes an oxidative stress response and eventual neuronal death in the hippocampus and cortex. Mol Neurodegener. 2018 02 01; 13(1):5.
Score: 0.092
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Nunomura A, Lee HG, Zhu X, Perry G. Consequences of RNA oxidation on protein synthesis rate and fidelity: implications for the pathophysiology of neuropsychiatric disorders. Biochem Soc Trans. 2017 Oct 15; 45(5):1053-1066.
Score: 0.089
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Smith MA, Richey Harris PL, Sayre LM, Beckman JS, Perry G. Widespread peroxynitrite-mediated damage in Alzheimer's disease. J Neurosci. 1997 Apr 15; 17(8):2653-7.
Score: 0.087
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Siedlak SL, Jiang Y, Huntley ML, Wang L, Gao J, Xie F, Liu J, Su B, Perry G, Wang X. TMEM230 Accumulation in Granulovacuolar Degeneration Bodies and Dystrophic Neurites of Alzheimer's Disease. J Alzheimers Dis. 2017; 58(4):1027-1033.
Score: 0.086
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DeWitt DA, Richey PL, Praprotnik D, Silver J, Perry G. Chondroitin sulfate proteoglycans are a common component of neuronal inclusions and astrocytic reaction in neurodegenerative diseases. Brain Res. 1994 Sep 05; 656(1):205-9.
Score: 0.073
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Bonda DJ, Wang X, Lee HG, Smith MA, Perry G, Zhu X. Neuronal failure in Alzheimer's disease: a view through the oxidative stress looking-glass. Neurosci Bull. 2014 Apr; 30(2):243-52.
Score: 0.071
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Kalaria RN, Bhatti SU, Lust WD, Perry G. The amyloid precursor protein in ischemic brain injury and chronic hypoperfusion. Ann N Y Acad Sci. 1993 Sep 24; 695:190-3.
Score: 0.068
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Bonda DJ, Stone JG, Torres SL, Siedlak SL, Perry G, Kryscio R, Jicha G, Casadesus G, Smith MA, Zhu X, Lee HG. Dysregulation of leptin signaling in Alzheimer disease: evidence for neuronal leptin resistance. J Neurochem. 2014 Jan; 128(1):162-72.
Score: 0.068
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Nunomura A, Tamaoki T, Motohashi N, Nakamura M, McKeel DW, Tabaton M, Lee HG, Smith MA, Perry G, Zhu X. The earliest stage of cognitive impairment in transition from normal aging to Alzheimer disease is marked by prominent RNA oxidation in vulnerable neurons. J Neuropathol Exp Neurol. 2012 Mar; 71(3):233-41.
Score: 0.061
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Kudo W, Lee HP, Zou WQ, Wang X, Perry G, Zhu X, Smith MA, Petersen RB, Lee HG. Cellular prion protein is essential for oligomeric amyloid-?-induced neuronal cell death. Hum Mol Genet. 2012 Mar 01; 21(5):1138-44.
Score: 0.060
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Zhu X, Castellani RJ, Moreira PI, Aliev G, Shenk JC, Siedlak SL, Harris PLR, Fujioka H, Sayre LM, Szweda PA, Szweda LI, Smith MA, Perry G. Hydroxynonenal-generated crosslinking fluorophore accumulation in Alzheimer disease reveals a dichotomy of protein turnover. Free Radic Biol Med. 2012 Feb 01; 52(3):699-704.
Score: 0.060
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Cras P, Kawai M, Lowery D, Gonzalez-DeWhitt P, Greenberg B, Perry G. Senile plaque neurites in Alzheimer disease accumulate amyloid precursor protein. Proc Natl Acad Sci U S A. 1991 Sep 01; 88(17):7552-6.
Score: 0.059
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Wang X, Su B, Liu W, He X, Gao Y, Castellani RJ, Perry G, Smith MA, Zhu X. DLP1-dependent mitochondrial fragmentation mediates 1-methyl-4-phenylpyridinium toxicity in neurons: implications for Parkinson's disease. Aging Cell. 2011 Oct; 10(5):807-23.
Score: 0.058
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Cras P, Kawai M, Siedlak S, Mulvihill P, Gambetti P, Lowery D, Gonzalez-DeWhitt P, Greenberg B, Perry G. Neuronal and microglial involvement in beta-amyloid protein deposition in Alzheimer's disease. Am J Pathol. 1990 Aug; 137(2):241-6.
Score: 0.055
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Valdez CM, Smith MA, Perry G, Phelix CF, Santamaria F. Cholesterol homeostasis markers are localized to mouse hippocampal pyramidal and granule layers. Hippocampus. 2010 Aug; 20(8):902-5.
Score: 0.055
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Wang X, Perry G, Smith MA, Zhu X. Amyloid-beta-derived diffusible ligands cause impaired axonal transport of mitochondria in neurons. Neurodegener Dis. 2010; 7(1-3):56-9.
Score: 0.053
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Su B, Wang X, Bonda D, Perry G, Smith M, Zhu X. Abnormal mitochondrial dynamics--a novel therapeutic target for Alzheimer's disease? Mol Neurobiol. 2010 Jun; 41(2-3):87-96.
Score: 0.053
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Wang X, Su B, Lee HG, Li X, Perry G, Smith MA, Zhu X. Impaired balance of mitochondrial fission and fusion in Alzheimer's disease. J Neurosci. 2009 Jul 15; 29(28):9090-103.
Score: 0.051
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Bonda DJ, Evans TA, Santocanale C, Llos? JC, Vi?a J, Bajic V, Castellani RJ, Siedlak SL, Perry G, Smith MA, Lee HG. Evidence for the progression through S-phase in the ectopic cell cycle re-entry of neurons in Alzheimer disease. Aging (Albany NY). 2009 Apr; 1(4):382-8.
Score: 0.050
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Castellani RJ, Zhu X, Lee HG, Smith MA, Perry G. Molecular pathogenesis of Alzheimer's disease: reductionist versus expansionist approaches. Int J Mol Sci. 2009 Mar; 10(3):1386-1406.
Score: 0.050
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Nunomura A, Hofer T, Moreira PI, Castellani RJ, Smith MA, Perry G. RNA oxidation in Alzheimer disease and related neurodegenerative disorders. Acta Neuropathol. 2009 Jul; 118(1):151-66.
Score: 0.050
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Lee HG, Casadesus G, Nunomura A, Zhu X, Castellani RJ, Richardson SL, Perry G, Felsher DW, Petersen RB, Smith MA. The neuronal expression of MYC causes a neurodegenerative phenotype in a novel transgenic mouse. Am J Pathol. 2009 Mar; 174(3):891-7.
Score: 0.049
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Lee HG, Zhu X, Casadesus G, Pall?s M, Camins A, O'Neill MJ, Nakanishi S, Perry G, Smith MA. The effect of mGluR2 activation on signal transduction pathways and neuronal cell survival. Brain Res. 2009 Jan 16; 1249:244-50.
Score: 0.049
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Obrenovich ME, Morales LA, Cobb CJ, Shenk JC, M?ndez GM, Fischbach K, Smith MA, Qasimov EK, Perry G, Aliev G. Insights into cerebrovascular complications and Alzheimer disease through the selective loss of GRK2 regulation. J Cell Mol Med. 2009 May; 13(5):853-65.
Score: 0.048
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Aliev G, Liu J, Shenk JC, Fischbach K, Pacheco GJ, Chen SG, Obrenovich ME, Ward WF, Richardson AG, Smith MA, Gasimov E, Perry G, Ames BN. Neuronal mitochondrial amelioration by feeding acetyl-L-carnitine and lipoic acid to aged rats. J Cell Mol Med. 2009 Feb; 13(2):320-33.
Score: 0.047
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Aliev G, Gasimov E, Obrenovich ME, Fischbach K, Shenk JC, Smith MA, Perry G. Atherosclerotic lesions and mitochondria DNA deletions in brain microvessels: implication in the pathogenesis of Alzheimer's disease. Vasc Health Risk Manag. 2008; 4(3):721-30.
Score: 0.046
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Zhu X, Siedlak SL, Wang Y, Perry G, Castellani RJ, Cohen ML, Smith MA. Neuronal binucleation in Alzheimer disease hippocampus. Neuropathol Appl Neurobiol. 2008 Aug; 34(4):457-65.
Score: 0.045
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Evans TA, Raina AK, Delacourte A, Aprelikova O, Lee HG, Zhu X, Perry G, Smith MA. BRCA1 may modulate neuronal cell cycle re-entry in Alzheimer disease. Int J Med Sci. 2007 May 12; 4(3):140-5.
Score: 0.044
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Casadesus G, Moreira PI, Nunomura A, Siedlak SL, Bligh-Glover W, Balraj E, Petot G, Smith MA, Perry G. Indices of metabolic dysfunction and oxidative stress. Neurochem Res. 2007 Apr-May; 32(4-5):717-22.
Score: 0.043
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Lee HG, Ueda M, Miyamoto Y, Yoneda Y, Perry G, Smith MA, Zhu X. Aberrant localization of importin alpha1 in hippocampal neurons in Alzheimer disease. Brain Res. 2006 Dec 08; 1124(1):1-4.
Score: 0.042
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Zhu X, Raina AK, Perry G, Smith MA. Apoptosis in Alzheimer disease: a mathematical improbability. Curr Alzheimer Res. 2006 Sep; 3(4):393-6.
Score: 0.042
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Nunomura A, Castellani RJ, Lee HG, Moreira PI, Zhu X, Perry G, Smith MA. Neuropathology in Alzheimer's disease: awaking from a hundred-year-old dream. Sci Aging Knowledge Environ. 2006 May 03; 2006(8):pe10.
Score: 0.041
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Strocchi P, Smith MA, Perry G, Tamagno E, Danni O, Pession A, Gaiba A, Dozza B. Clusterin up-regulation following sub-lethal oxidative stress and lipid peroxidation in human neuroblastoma cells. Neurobiol Aging. 2006 Nov; 27(11):1588-94.
Score: 0.040
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Moreira PI, Honda K, Zhu X, Nunomura A, Casadesus G, Smith MA, Perry G. Brain and brawn: parallels in oxidative strength. Neurology. 2006 Jan 24; 66(2 Suppl 1):S97-101.
Score: 0.040
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Webber KM, Raina AK, Marlatt MW, Zhu X, Prat MI, Morelli L, Casadesus G, Perry G, Smith MA. The cell cycle in Alzheimer disease: a unique target for neuropharmacology. Mech Ageing Dev. 2005 Oct; 126(10):1019-25.
Score: 0.039
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Lin D, Lee HG, Liu Q, Perry G, Smith MA, Sayre LM. 4-Oxo-2-nonenal is both more neurotoxic and more protein reactive than 4-hydroxy-2-nonenal. Chem Res Toxicol. 2005 Aug; 18(8):1219-31.
Score: 0.039
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Honda K, Smith MA, Zhu X, Baus D, Merrick WC, Tartakoff AM, Hattier T, Harris PL, Siedlak SL, Fujioka H, Liu Q, Moreira PI, Miller FP, Nunomura A, Shimohama S, Perry G. Ribosomal RNA in Alzheimer disease is oxidized by bound redox-active iron. J Biol Chem. 2005 Jun 03; 280(22):20978-86.
Score: 0.038
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Tamagno E, Parola M, Bardini P, Piccini A, Borghi R, Guglielmotto M, Santoro G, Davit A, Danni O, Smith MA, Perry G, Tabaton M. Beta-site APP cleaving enzyme up-regulation induced by 4-hydroxynonenal is mediated by stress-activated protein kinases pathways. J Neurochem. 2005 Feb; 92(3):628-36.
Score: 0.037
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Sahin M, Karauzum SB, Perry G, Smith MA, Aliciguzel Y. Retinoic acid isomers protect hippocampal neurons from amyloid-beta induced neurodegeneration. Neurotox Res. 2005; 7(3):243-50.
Score: 0.037
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Lee HG, Moreira PI, Zhu X, Smith MA, Perry G. Staying connected: synapses in Alzheimer disease. Am J Pathol. 2004 Nov; 165(5):1461-4.
Score: 0.037
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Zhu X, Wang Y, Ogawa O, Lee HG, Raina AK, Siedlak SL, Harris PL, Fujioka H, Shimohama S, Tabaton M, Atwood CS, Petersen RB, Perry G, Smith MA. Neuroprotective properties of Bcl-w in Alzheimer disease. J Neurochem. 2004 Jun; 89(5):1233-40.
Score: 0.036
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Lee HG, Ogawa O, Zhu X, O'Neill MJ, Petersen RB, Castellani RJ, Ghanbari H, Perry G, Smith MA. Aberrant expression of metabotropic glutamate receptor 2 in the vulnerable neurons of Alzheimer's disease. Acta Neuropathol. 2004 Apr; 107(4):365-71.
Score: 0.035
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Liu T, Perry G, Chan HW, Verdile G, Martins RN, Smith MA, Atwood CS. Amyloid-beta-induced toxicity of primary neurons is dependent upon differentiation-associated increases in tau and cyclin-dependent kinase 5 expression. J Neurochem. 2004 Feb; 88(3):554-63.
Score: 0.035
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Perry G, Nunomura A, Raina AK, Aliev G, Siedlak SL, Harris PL, Casadesus G, Petersen RB, Bligh-Glover W, Balraj E, Petot GJ, Smith MA. A metabolic basis for Alzheimer disease. Neurochem Res. 2003 Oct; 28(10):1549-52.
Score: 0.034
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Zhu X, Raina AK, Lee HG, Chao M, Nunomura A, Tabaton M, Petersen RB, Perry G, Smith MA. Oxidative stress and neuronal adaptation in Alzheimer disease: the role of SAPK pathways. Antioxid Redox Signal. 2003 Oct; 5(5):571-6.
Score: 0.034
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Kitamura Y, Tsuchiya D, Takata K, Shibagaki K, Taniguchi T, Smith MA, Perry G, Miki H, Takenawa T, Shimohama S. Possible involvement of Wiskott-Aldrich syndrome protein family in aberrant neuronal sprouting in Alzheimer's disease. Neurosci Lett. 2003 Aug 07; 346(3):149-52.
Score: 0.034
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Cash AD, Aliev G, Siedlak SL, Nunomura A, Fujioka H, Zhu X, Raina AK, Vinters HV, Tabaton M, Johnson AB, Paula-Barbosa M, Av?la J, Jones PK, Castellani RJ, Smith MA, Perry G. Microtubule reduction in Alzheimer's disease and aging is independent of tau filament formation. Am J Pathol. 2003 May; 162(5):1623-7.
Score: 0.033
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Bruckner SR, Perry G, Estus S. 4-hydroxynonenal contributes to NGF withdrawal-induced neuronal apoptosis. J Neurochem. 2003 May; 85(4):999-1005.
Score: 0.033
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G?mez-Ramos A, D?az-Nido J, Smith MA, Perry G, Avila J. Effect of the lipid peroxidation product acrolein on tau phosphorylation in neural cells. J Neurosci Res. 2003 Mar 15; 71(6):863-70.
Score: 0.033
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Raina AK, Zhu X, Shimohama S, Perry G, Smith MA. Tipping the apoptotic balance in Alzheimer's disease: the abortosis concept. Cell Biochem Biophys. 2003; 39(3):249-55.
Score: 0.032
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Castellani R, Hirai K, Aliev G, Drew KL, Nunomura A, Takeda A, Cash AD, Obrenovich ME, Perry G, Smith MA. Role of mitochondrial dysfunction in Alzheimer's disease. J Neurosci Res. 2002 Nov 01; 70(3):357-60.
Score: 0.032
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Tamagno E, Bardini P, Obbili A, Vitali A, Borghi R, Zaccheo D, Pronzato MA, Danni O, Smith MA, Perry G, Tabaton M. Oxidative stress increases expression and activity of BACE in NT2 neurons. Neurobiol Dis. 2002 Aug; 10(3):279-88.
Score: 0.031
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Atwood CS, Martins RN, Smith MA, Perry G. Senile plaque composition and posttranslational modification of amyloid-beta peptide and associated proteins. Peptides. 2002 Jul; 23(7):1343-50.
Score: 0.031
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Pappolla MA, Simovich MJ, Bryant-Thomas T, Chyan YJ, Poeggeler B, Dubocovich M, Bick R, Perry G, Cruz-Sanchez F, Smith MA. The neuroprotective activities of melatonin against the Alzheimer beta-protein are not mediated by melatonin membrane receptors. J Pineal Res. 2002 Apr; 32(3):135-42.
Score: 0.031
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Zhu X, Castellani RJ, Takeda A, Nunomura A, Atwood CS, Perry G, Smith MA. Differential activation of neuronal ERK, JNK/SAPK and p38 in Alzheimer disease: the 'two hit' hypothesis. Mech Ageing Dev. 2001 Dec; 123(1):39-46.
Score: 0.030
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Clapp-Lilly KL, Smith MA, Perry G, Harris PL, Zhu X, Duffy LK. Melatonin acts as antioxidant and pro-oxidant in an organotypic slice culture model of Alzheimer's disease. Neuroreport. 2001 May 08; 12(6):1277-80.
Score: 0.029
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Rottkamp CA, Raina AK, Zhu X, Gaier E, Bush AI, Atwood CS, Chevion M, Perry G, Smith MA. Redox-active iron mediates amyloid-beta toxicity. Free Radic Biol Med. 2001 Feb 15; 30(4):447-50.
Score: 0.028
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Perry G, Avila J, Espey MG, Wink DA, Atwood CS, Smith MA. Biochemistry of neurodegeneration. Science. 2001 Jan 26; 291(5504):595-7.
Score: 0.028
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Zhu X, Raina AK, Rottkamp CA, Aliev G, Perry G, Boux H, Smith MA. Activation and redistribution of c-jun N-terminal kinase/stress activated protein kinase in degenerating neurons in Alzheimer's disease. J Neurochem. 2001 Jan; 76(2):435-41.
Score: 0.028
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Wang L, Liu M, Gao J, Smith AM, Fujioka H, Liang J, Perry G, Wang X. Mitochondrial Fusion Suppresses Tau Pathology-Induced Neurodegeneration and Cognitive Decline. J Alzheimers Dis. 2021; 84(3):1057-1069.
Score: 0.028
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Nunomura A, Perry G, Pappolla MA, Friedland RP, Hirai K, Chiba S, Smith MA. Neuronal oxidative stress precedes amyloid-beta deposition in Down syndrome. J Neuropathol Exp Neurol. 2000 Nov; 59(11):1011-7.
Score: 0.028
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Takeda A, Smith MA, Avil? J, Nunomura A, Siedlak SL, Zhu X, Perry G, Sayre LM. In Alzheimer's disease, heme oxygenase is coincident with Alz50, an epitope of tau induced by 4-hydroxy-2-nonenal modification. J Neurochem. 2000 Sep; 75(3):1234-41.
Score: 0.028
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Takeda A, Perry G, Abraham NG, Dwyer BE, Kutty RK, Laitinen JT, Petersen RB, Smith MA. Overexpression of heme oxygenase in neuronal cells, the possible interaction with Tau. J Biol Chem. 2000 Feb 25; 275(8):5395-9.
Score: 0.027
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Kim HT, Russell RL, Raina AK, Harris PL, Siedlak SL, Zhu X, Petersen RB, Shimohama S, Smith MA, Perry G. Protein disulfide isomerase in Alzheimer disease. Antioxid Redox Signal. 2000; 2(3):485-9.
Score: 0.026
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Gao J, Wang L, Gao C, Arakawa H, Perry G, Wang X. TDP-43 inhibitory peptide alleviates neurodegeneration and memory loss in an APP transgenic mouse model for Alzheimer's disease. Biochim Biophys Acta Mol Basis Dis. 2020 01 01; 1866(1):165580.
Score: 0.026
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Gao J, Wang L, Yan T, Perry G, Wang X. TDP-43 proteinopathy and mitochondrial abnormalities in neurodegeneration. Mol Cell Neurosci. 2019 10; 100:103396.
Score: 0.026
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Zhang J, Perry G, Smith MA, Robertson D, Olson SJ, Graham DG, Montine TJ. Parkinson's disease is associated with oxidative damage to cytoplasmic DNA and RNA in substantia nigra neurons. Am J Pathol. 1999 May; 154(5):1423-9.
Score: 0.025
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Nunomura A, Perry G, Pappolla MA, Wade R, Hirai K, Chiba S, Smith MA. RNA oxidation is a prominent feature of vulnerable neurons in Alzheimer's disease. J Neurosci. 1999 Mar 15; 19(6):1959-64.
Score: 0.025
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Wang C, Zhao F, Shen K, Wang W, Siedlak SL, Lee HG, Phelix CF, Perry G, Shen L, Tang B, Yan R, Zhu X. The sterol regulatory element-binding protein 2 is dysregulated by tau alterations in Alzheimer disease. Brain Pathol. 2019 07; 29(4):530-543.
Score: 0.025
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Liu M, Wang L, Gao J, Dong Q, Perry G, Ma X, Wang X. Inhibition of Calpain Protects Against Tauopathy in Transgenic P301S Tau Mice. J Alzheimers Dis. 2019; 69(4):1077-1087.
Score: 0.025
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Nunomura A, Perry G, Hirai K, Aliev G, Takeda A, Chiba S, Smith MA. Neuronal RNA oxidation in Alzheimer's disease and Down's syndrome. Ann N Y Acad Sci. 1999; 893:362-4.
Score: 0.025
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Velasco ME, Smith MA, Siedlak SL, Nunomura A, Perry G. Striation is the characteristic neuritic abnormality in Alzheimer disease. Brain Res. 1998 Dec 07; 813(2):329-33.
Score: 0.024
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Smith MA, Vas?k M, Knipp M, Castellani RJ, Perry G. Dimethylargininase, a nitric oxide regulatory protein, in Alzheimer disease. Free Radic Biol Med. 1998 Nov 15; 25(8):898-902.
Score: 0.024
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Hattori N, Kitagawa K, Higashida T, Yagyu K, Shimohama S, Wataya T, Perry G, Smith MA, Inagaki C. CI-ATPase and Na+/K(+)-ATPase activities in Alzheimer's disease brains. Neurosci Lett. 1998 Oct 02; 254(3):141-4.
Score: 0.024
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Smith MA, Sayre LM, Anderson VE, Harris PL, Beal MF, Kowall N, Perry G. Cytochemical demonstration of oxidative damage in Alzheimer disease by immunochemical enhancement of the carbonyl reaction with 2,4-dinitrophenylhydrazine. J Histochem Cytochem. 1998 Jun; 46(6):731-5.
Score: 0.024
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Vasquez V, Mitra J, Perry G, Rao KS, Hegde ML. An Inducible Alpha-Synuclein Expressing Neuronal Cell Line Model for Parkinson's Disease1. J Alzheimers Dis. 2018; 66(2):453-460.
Score: 0.023
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Wang W, Yin J, Ma X, Zhao F, Siedlak SL, Wang Z, Torres S, Fujioka H, Xu Y, Perry G, Zhu X. Inhibition of mitochondrial fragmentation protects against Alzheimer's disease in rodent model. Hum Mol Genet. 2017 11 01; 26(21):4118-4131.
Score: 0.023
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Castellani R, Smith MA, Richey PL, Perry G. Glycoxidation and oxidative stress in Parkinson disease and diffuse Lewy body disease. Brain Res. 1996 Oct 21; 737(1-2):195-200.
Score: 0.021
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Smith MA, Sayre LM, Monnier VM, Perry G. Oxidative posttranslational modifications in Alzheimer disease. A possible pathogenic role in the formation of senile plaques and neurofibrillary tangles. Mol Chem Neuropathol. 1996 May-Aug; 28(1-3):41-8.
Score: 0.020
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Castellani R, Smith MA, Richey PL, Kalaria R, Gambetti P, Perry G. Evidence for oxidative stress in Pick disease and corticobasal degeneration. Brain Res. 1995 Oct 23; 696(1-2):268-71.
Score: 0.020
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Smith MA, Sayre LM, Monnier VM, Perry G. Radical AGEing in Alzheimer's disease. Trends Neurosci. 1995 Apr; 18(4):172-6.
Score: 0.019
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Richey PL, Siedlak SL, Smith MA, Perry G. Apolipoprotein E interaction with the neurofibrillary tangles and senile plaques in Alzheimer disease: implications for disease pathogenesis. Biochem Biophys Res Commun. 1995 Mar 17; 208(2):657-63.
Score: 0.019
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Smith MA, Perry G. Alzheimer disease: an imbalance of proteolytic regulation? Med Hypotheses. 1994 Apr; 42(4):277-9.
Score: 0.018
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Paley EL, Perry G, Sokolova O. Tryptamine induces axonopathy and mitochondriopathy mimicking neurodegenerative diseases via tryptophanyl-tRNA deficiency. Curr Alzheimer Res. 2013 Nov; 10(9):987-1004.
Score: 0.017
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Zhu X, Perry G, Smith MA, Wang X. Abnormal mitochondrial dynamics in the pathogenesis of Alzheimer's disease. J Alzheimers Dis. 2013; 33 Suppl 1:S253-62.
Score: 0.016
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Candeias E, Duarte AI, Carvalho C, Correia SC, Cardoso S, Santos RX, Pl?cido AI, Perry G, Moreira PI. The impairment of insulin signaling in Alzheimer's disease. IUBMB Life. 2012 Dec; 64(12):951-7.
Score: 0.016
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Wang X, Yan MH, Fujioka H, Liu J, Wilson-Delfosse A, Chen SG, Perry G, Casadesus G, Zhu X. LRRK2 regulates mitochondrial dynamics and function through direct interaction with DLP1. Hum Mol Genet. 2012 May 01; 21(9):1931-44.
Score: 0.015
-
Bonda DJ, Castellani RJ, Zhu X, Nunomura A, Lee HG, Perry G, Smith MA. A novel perspective on tau in Alzheimer's disease. Curr Alzheimer Res. 2011 Sep; 8(6):639-42.
Score: 0.015
-
Tabaton M, Cammarata S, Mancardi G, Manetto V, Autilio-Gambetti L, Perry G, Gambetti P. Ultrastructural localization of beta-amyloid, tau, and ubiquitin epitopes in extracellular neurofibrillary tangles. Proc Natl Acad Sci U S A. 1991 Mar 15; 88(6):2098-102.
Score: 0.014
-
Heath JE, Siedlak SL, Zhu X, Lee HG, Thakur A, Yan R, Perry G, Smith MA, Castellani RJ. Widespread distribution of reticulon-3 in various neurodegenerative diseases. Neuropathology. 2010 Dec; 30(6):574-9.
Score: 0.014
-
Bonda DJ, Wang X, Perry G, Smith MA, Zhu X. Mitochondrial dynamics in Alzheimer's disease: opportunities for future treatment strategies. Drugs Aging. 2010 Mar 01; 27(3):181-92.
Score: 0.013
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Bonda DJ, Mailankot M, Stone JG, Garrett MR, Staniszewska M, Castellani RJ, Siedlak SL, Zhu X, Lee HG, Perry G, Nagaraj RH, Smith MA. Indoleamine 2,3-dioxygenase and 3-hydroxykynurenine modifications are found in the neuropathology of Alzheimer's disease. Redox Rep. 2010; 15(4):161-8.
Score: 0.013
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Perez M, Santa-Maria I, Gomez de Barreda E, Zhu X, Cuadros R, Cabrero JR, Sanchez-Madrid F, Dawson HN, Vitek MP, Perry G, Smith MA, Avila J. Tau--an inhibitor of deacetylase HDAC6 function. J Neurochem. 2009 Jun; 109(6):1756-66.
Score: 0.013
-
Wang X, Su B, Zheng L, Perry G, Smith MA, Zhu X. The role of abnormal mitochondrial dynamics in the pathogenesis of Alzheimer's disease. J Neurochem. 2009 May; 109 Suppl 1:153-9.
Score: 0.013
-
Liu G, Men P, Kudo W, Perry G, Smith MA. Nanoparticle-chelator conjugates as inhibitors of amyloid-beta aggregation and neurotoxicity: a novel therapeutic approach for Alzheimer disease. Neurosci Lett. 2009 May 22; 455(3):187-90.
Score: 0.012
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Tabaton M, Perry G, Autilio-Gambetti L, Manetto V, Gambetti P. Influence of neuronal location on antigenic properties of neurofibrillary tangles. Ann Neurol. 1988 Jun; 23(6):604-10.
Score: 0.012
-
Sayre LM, Perry G, Smith MA. Oxidative stress and neurotoxicity. Chem Res Toxicol. 2008 Jan; 21(1):172-88.
Score: 0.011
-
Wang X, Su B, Perry G, Smith MA, Zhu X. Insights into amyloid-beta-induced mitochondrial dysfunction in Alzheimer disease. Free Radic Biol Med. 2007 Dec 15; 43(12):1569-73.
Score: 0.011
-
Thakur A, Wang X, Siedlak SL, Perry G, Smith MA, Zhu X. c-Jun phosphorylation in Alzheimer disease. J Neurosci Res. 2007 Jun; 85(8):1668-73.
Score: 0.011
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Perry G, Friedman R, Shaw G, Chau V. Ubiquitin is detected in neurofibrillary tangles and senile plaque neurites of Alzheimer disease brains. Proc Natl Acad Sci U S A. 1987 May; 84(9):3033-6.
Score: 0.011
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Petersen RB, Nunomura A, Lee HG, Casadesus G, Perry G, Smith MA, Zhu X. Signal transduction cascades associated with oxidative stress in Alzheimer's disease. J Alzheimers Dis. 2007 May; 11(2):143-52.
Score: 0.011
-
Galloway PG, Perry G, Gambetti P. Hirano body filaments contain actin and actin-associated proteins. J Neuropathol Exp Neurol. 1987 Mar; 46(2):185-99.
Score: 0.011
-
Lee HG, Zhu X, Castellani RJ, Nunomura A, Perry G, Smith MA. Amyloid-beta in Alzheimer disease: the null versus the alternate hypotheses. J Pharmacol Exp Ther. 2007 Jun; 321(3):823-9.
Score: 0.011
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Nunomura A, Castellani RJ, Zhu X, Moreira PI, Perry G, Smith MA. Involvement of oxidative stress in Alzheimer disease. J Neuropathol Exp Neurol. 2006 Jul; 65(7):631-41.
Score: 0.010
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Zhu X, Perry G, Moreira PI, Aliev G, Cash AD, Hirai K, Smith MA. Mitochondrial abnormalities and oxidative imbalance in Alzheimer disease. J Alzheimers Dis. 2006 Jul; 9(2):147-53.
Score: 0.010
-
Forero DA, Casadesus G, Perry G, Arboleda H. Synaptic dysfunction and oxidative stress in Alzheimer's disease: emerging mechanisms. J Cell Mol Med. 2006 Jul-Sep; 10(3):796-805.
Score: 0.010
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Aliev G, Miller JP, Leifer DW, Obrenovich ME, Shenk JC, Smith MA, Lamanna JC, Perry G, Lust DW, Cohen AR. Ultrastructural analysis of a murine model of congenital hydrocephalus produced by overexpression of transforming growth factor-beta1 in the central nervous system. J Submicrosc Cytol Pathol. 2006 Jun-Sep; 38(2-3):85-91.
Score: 0.010
-
Zhu X, Mei M, Lee HG, Wang Y, Han J, Perry G, Smith MA. P38 activation mediates amyloid-beta cytotoxicity. Neurochem Res. 2005 Jun-Jul; 30(6-7):791-6.
Score: 0.010
-
Webber KM, Smith MA, Lee HG, Harris PL, Moreira P, Perry G, Zhu X. Mitogen- and stress-activated protein kinase 1: convergence of the ERK and p38 pathways in Alzheimer's disease. J Neurosci Res. 2005 Feb 15; 79(4):554-60.
Score: 0.009
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Santa-Mar?a I, Smith MA, Perry G, Hern?ndez F, Avila J, Moreno FJ. Effect of quinones on microtubule polymerization: a link between oxidative stress and cytoskeletal alterations in Alzheimer's disease. Biochim Biophys Acta. 2005 Jun 10; 1740(3):472-80.
Score: 0.009
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Castellani RJ, Honda K, Zhu X, Cash AD, Nunomura A, Perry G, Smith MA. Contribution of redox-active iron and copper to oxidative damage in Alzheimer disease. Ageing Res Rev. 2004 Jul; 3(3):319-26.
Score: 0.009
-
Lee HG, Casadesus G, Zhu X, Takeda A, Perry G, Smith MA. Challenging the amyloid cascade hypothesis: senile plaques and amyloid-beta as protective adaptations to Alzheimer disease. Ann N Y Acad Sci. 2004 Jun; 1019:1-4.
Score: 0.009
-
Lee HG, Casadesus G, Zhu X, Joseph JA, Perry G, Smith MA. Perspectives on the amyloid-beta cascade hypothesis. J Alzheimers Dis. 2004 Apr; 6(2):137-45.
Score: 0.009
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Zhu X, McShea A, Harris PL, Raina AK, Castellani RJ, Funk JO, Shah S, Atwood C, Bowen R, Bowser R, Morelli L, Perry G, Smith MA. Elevated expression of a regulator of the G2/M phase of the cell cycle, neuronal CIP-1-associated regulator of cyclin B, in Alzheimer's disease. J Neurosci Res. 2004 Mar 01; 75(5):698-703.
Score: 0.009
-
Marlatt M, Lee HG, Perry G, Smith MA, Zhu X. Sources and mechanisms of cytoplasmic oxidative damage in Alzheimer's disease. Acta Neurobiol Exp (Wars). 2004; 64(1):81-7.
Score: 0.009
-
Zhu X, Sun Z, Lee HG, Siedlak SL, Perry G, Smith MA. Distribution, levels, and activation of MEK1 in Alzheimer's disease. J Neurochem. 2003 Jul; 86(1):136-42.
Score: 0.008
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Cash AD, Perry G, Ogawa O, Raina AK, Zhu X, Smith MA. Is Alzheimer's disease a mitochondrial disorder? Neuroscientist. 2002 Oct; 8(5):489-96.
Score: 0.008
-
Rottkamp CA, Atwood CS, Joseph JA, Nunomura A, Perry G, Smith MA. The state versus amyloid-beta: the trial of the most wanted criminal in Alzheimer disease. Peptides. 2002 Jul; 23(7):1333-41.
Score: 0.008
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Castellani RJ, Perry G, Siedlak SL, Nunomura A, Shimohama S, Zhang J, Montine T, Sayre LM, Smith MA. Hydroxynonenal adducts indicate a role for lipid peroxidation in neocortical and brainstem Lewy bodies in humans. Neurosci Lett. 2002 Feb 08; 319(1):25-8.
Score: 0.008
-
Nunomura A, Perry G, Aliev G, Hirai K, Takeda A, Balraj EK, Jones PK, Ghanbari H, Wataya T, Shimohama S, Chiba S, Atwood CS, Petersen RB, Smith MA. Oxidative damage is the earliest event in Alzheimer disease. J Neuropathol Exp Neurol. 2001 Aug; 60(8):759-67.
Score: 0.007
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Hirai K, Aliev G, Nunomura A, Fujioka H, Russell RL, Atwood CS, Johnson AB, Kress Y, Vinters HV, Tabaton M, Shimohama S, Cash AD, Siedlak SL, Harris PL, Jones PK, Petersen RB, Perry G, Smith MA. Mitochondrial abnormalities in Alzheimer's disease. J Neurosci. 2001 May 01; 21(9):3017-23.
Score: 0.007
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Raina AK, Hochman A, Zhu X, Rottkamp CA, Nunomura A, Siedlak SL, Boux H, Castellani RJ, Perry G, Smith MA. Abortive apoptosis in Alzheimer's disease. Acta Neuropathol. 2001 Apr; 101(4):305-10.
Score: 0.007
-
Zhu X, Rottkamp CA, Boux H, Takeda A, Perry G, Smith MA. Activation of p38 kinase links tau phosphorylation, oxidative stress, and cell cycle-related events in Alzheimer disease. J Neuropathol Exp Neurol. 2000 Oct; 59(10):880-8.
Score: 0.007
-
Rottkamp CA, Nunomura A, Hirai K, Sayre LM, Perry G, Smith MA. Will antioxidants fulfill their expectations for the treatment of Alzheimer disease? Mech Ageing Dev. 2000 Jul 31; 116(2-3):169-79.
Score: 0.007
-
Cuajungco MP, Goldstein LE, Nunomura A, Smith MA, Lim JT, Atwood CS, Huang X, Farrag YW, Perry G, Bush AI. Evidence that the beta-amyloid plaques of Alzheimer's disease represent the redox-silencing and entombment of abeta by zinc. J Biol Chem. 2000 Jun 30; 275(26):19439-42.
Score: 0.007
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Sayre LM, Perry G, Smith MA. In situ methods for detection and localization of markers of oxidative stress: application in neurodegenerative disorders. Methods Enzymol. 1999; 309:133-52.
Score: 0.006
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Sayre LM, Zelasko DA, Harris PL, Perry G, Salomon RG, Smith MA. 4-Hydroxynonenal-derived advanced lipid peroxidation end products are increased in Alzheimer's disease. J Neurochem. 1997 May; 68(5):2092-7.
Score: 0.005
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Kalaria RN, Bhatti SU, Palatinsky EA, Pennington DH, Shelton ER, Chan HW, Perry G, Lust WD. Accumulation of the beta amyloid precursor protein at sites of ischemic injury in rat brain. Neuroreport. 1993 Feb; 4(2):211-4.
Score: 0.004
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Whitehouse PJ, Gambetti P, Harik SI, Kalaria RN, Perry G, Younkin SI, Tabaton M, Unnerstall JR. Neurochemistry of dementia: establishing the links. Prog Clin Biol Res. 1989; 317:131-42.
Score: 0.003
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Tabaton M, Whitehouse PJ, Perry G, Davies P, Autilio-Gambetti L, Gambetti P. Alz 50 recognizes abnormal filaments in Alzheimer's disease and progressive supranuclear palsy. Ann Neurol. 1988 Sep; 24(3):407-13.
Score: 0.003
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Galloway PG, Perry G, Kosik KS, Gambetti P. Hirano bodies contain tau protein. Brain Res. 1987 Feb 17; 403(2):337-40.
Score: 0.003