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Connection

George Perry to Brain

This is a "connection" page, showing publications George Perry has written about Brain.
Connection Strength

11.960
  1. Plascencia-Villa G, Castellani RJ, Perry G. Central role of brain regulatory T cells in the inflammatory cascade in Alzheimer's disease. Proc Natl Acad Sci U S A. 2024 Aug 06; 121(32):e2412255121.
    View in: PubMed
    Score: 0.561
  2. Liang J, LaFleur B, Hussainy S, Perry G. Gene Co-Expression Analysis of Multiple Brain Tissues Reveals Correlation of FAM222A Expression with Multiple Alzheimer's Disease-Related Genes. J Alzheimers Dis. 2024; 99(s2):S249-S263.
    View in: PubMed
    Score: 0.539
  3. Mandal PK, Perry G. SWADESH: A Comprehensive Platform for Multimodal Data and Analytics for Advanced Research in Alzheimer's Disease and Other Brain Disorders. J Alzheimers Dis. 2022; 85(1):1-5.
    View in: PubMed
    Score: 0.470
  4. Nunomura A, Perry G. RNA and Oxidative Stress in Alzheimer's Disease: Focus on microRNAs. Oxid Med Cell Longev. 2020; 2020:2638130.
    View in: PubMed
    Score: 0.435
  5. Mahmoudi M, Pakpour S, Perry G. Drug-Abuse Nanotechnology: Opportunities and Challenges. ACS Chem Neurosci. 2018 10 17; 9(10):2288-2298.
    View in: PubMed
    Score: 0.366
  6. Paley EL, Perry G. Towards an Integrative Understanding of tRNA Aminoacylation-Diet-Host-Gut Microbiome Interactions in Neurodegeneration. Nutrients. 2018 Mar 26; 10(4).
    View in: PubMed
    Score: 0.362
  7. Plascencia-Villa G, Ponce A, Collingwood JF, Arellano-Jim?nez MJ, Zhu X, Rogers JT, Betancourt I, Jos?-Yacam?n M, Perry G. High-resolution analytical imaging and electron holography of magnetite particles in amyloid cores of Alzheimer's disease. Sci Rep. 2016 04 28; 6:24873.
    View in: PubMed
    Score: 0.317
  8. Ashford JW, Salehi A, Furst A, Bayley P, Frisoni GB, Jack CR, Sabri O, Adamson MM, Coburn KL, Olichney J, Schuff N, Spielman D, Edland SD, Black S, Rosen A, Kennedy D, Weiner M, Perry G. Imaging the Alzheimer brain. J Alzheimers Dis. 2011; 26 Suppl 3:1-27.
    View in: PubMed
    Score: 0.219
  9. Nunomura A, Tamaoki T, Tanaka K, Motohashi N, Nakamura M, Hayashi T, Yamaguchi H, Shimohama S, Lee HG, Zhu X, Smith MA, Perry G. Intraneuronal amyloid beta accumulation and oxidative damage to nucleic acids in Alzheimer disease. Neurobiol Dis. 2010 Mar; 37(3):731-7.
    View in: PubMed
    Score: 0.204
  10. Nunomura A, Hofer T, Moreira PI, Castellani RJ, Smith MA, Perry G. RNA oxidation in Alzheimer disease and related neurodegenerative disorders. Acta Neuropathol. 2009 Jul; 118(1):151-66.
    View in: PubMed
    Score: 0.193
  11. Aliev G, Gasimov E, Obrenovich ME, Fischbach K, Shenk JC, Smith MA, Perry G. Atherosclerotic lesions and mitochondria DNA deletions in brain microvessels: implication in the pathogenesis of Alzheimer's disease. Vasc Health Risk Manag. 2008; 4(3):721-30.
    View in: PubMed
    Score: 0.178
  12. Moreira PI, Siedlak SL, Wang X, Santos MS, Oliveira CR, Tabaton M, Nunomura A, Szweda LI, Aliev G, Smith MA, Zhu X, Perry G. Autophagocytosis of mitochondria is prominent in Alzheimer disease. J Neuropathol Exp Neurol. 2007 Jun; 66(6):525-32.
    View in: PubMed
    Score: 0.171
  13. Zhu X, Smith MA, Honda K, Aliev G, Moreira PI, Nunomura A, Casadesus G, Harris PL, Siedlak SL, Perry G. Vascular oxidative stress in Alzheimer disease. J Neurol Sci. 2007 Jun 15; 257(1-2):240-6.
    View in: PubMed
    Score: 0.168
  14. Perry G. Solving the insoluble. J Alzheimers Dis. 2006; 9(3 Suppl):301-4.
    View in: PubMed
    Score: 0.155
  15. Petersen RB, Siedlak SL, Lee HG, Kim YS, Nunomura A, Tagliavini F, Ghetti B, Cras P, Moreira PI, Castellani RJ, Guentchev M, Budka H, Ironside JW, Gambetti P, Smith MA, Perry G. Redox metals and oxidative abnormalities in human prion diseases. Acta Neuropathol. 2005 Sep; 110(3):232-8.
    View in: PubMed
    Score: 0.151
  16. Nunomura A, Chiba S, Lippa CF, Cras P, Kalaria RN, Takeda A, Honda K, Smith MA, Perry G. Neuronal RNA oxidation is a prominent feature of familial Alzheimer's disease. Neurobiol Dis. 2004 Oct; 17(1):108-13.
    View in: PubMed
    Score: 0.142
  17. Aliev G, Seyidova D, Lamb BT, Obrenovich ME, Siedlak SL, Vinters HV, Friedland RP, LaManna JC, Smith MA, Perry G. Mitochondria and vascular lesions as a central target for the development of Alzheimer's disease and Alzheimer disease-like pathology in transgenic mice. Neurol Res. 2003 Sep; 25(6):665-74.
    View in: PubMed
    Score: 0.132
  18. Cash AD, Aliev G, Siedlak SL, Nunomura A, Fujioka H, Zhu X, Raina AK, Vinters HV, Tabaton M, Johnson AB, Paula-Barbosa M, Av?la J, Jones PK, Castellani RJ, Smith MA, Perry G. Microtubule reduction in Alzheimer's disease and aging is independent of tau filament formation. Am J Pathol. 2003 May; 162(5):1623-7.
    View in: PubMed
    Score: 0.129
  19. Plascencia-Villa G, Perry G. Neuropathologic Changes Provide Insights into Key Mechanisms of Alzheimer Disease and Related Dementia. Am J Pathol. 2022 10; 192(10):1340-1346.
    View in: PubMed
    Score: 0.122
  20. Smith MA, Atwood CS, Joseph JA, Perry G. Ill-fated amyloid-beta vaccine. J Neurosci Res. 2002 Aug 01; 69(3):285.
    View in: PubMed
    Score: 0.122
  21. Perry G, Nunomura A, Cash AD, Taddeo MA, Hirai K, Aliev G, Avila J, Wataya T, Shimohama S, Atwood CS, Smith MA. Reactive oxygen: its sources and significance in Alzheimer disease. J Neural Transm Suppl. 2002; (62):69-75.
    View in: PubMed
    Score: 0.117
  22. Pappolla MA, Perry G, Fang X, Zagorski M, Sambamurti K, Poeggeler B. Indoles as essential mediators in the gut-brain axis. Their role in Alzheimer's disease. Neurobiol Dis. 2021 08; 156:105403.
    View in: PubMed
    Score: 0.113
  23. Orkin JD, Montague MJ, Tejada-Martinez D, de Manuel M, Del Campo J, Cheves Hernandez S, Di Fiore A, Fontsere C, Hodgson JA, Janiak MC, Kuderna LFK, Lizano E, Martin MP, Niimura Y, Perry GH, Valverde CS, Tang J, Warren WC, de Magalh?es JP, Kawamura S, Marqu?s-Bonet T, Krawetz R, Melin AD. The genomics of ecological flexibility, large brains, and long lives in capuchin monkeys revealed with fecalFACS. Proc Natl Acad Sci U S A. 2021 02 16; 118(7).
    View in: PubMed
    Score: 0.110
  24. Perry G, Avila J, Espey MG, Wink DA, Atwood CS, Smith MA. Biochemistry of neurodegeneration. Science. 2001 Jan 26; 291(5504):595-7.
    View in: PubMed
    Score: 0.110
  25. Avila J, Perry G. A Multilevel View of the Development of Alzheimer's Disease. Neuroscience. 2021 03 01; 457:283-293.
    View in: PubMed
    Score: 0.109
  26. Kelley AR, Colley M, Dyer S, Bach SBH, Zhu X, Perry G. Ethanol-Fixed, Paraffin-Embedded Tissue Imaging: Implications for Alzheimer's Disease Research. J Am Soc Mass Spectrom. 2020 Dec 02; 31(12):2416-2420.
    View in: PubMed
    Score: 0.107
  27. Wang W, Zhao F, Ma X, Perry G, Zhu X. Mitochondria dysfunction in the pathogenesis of Alzheimer's disease: recent advances. Mol Neurodegener. 2020 05 29; 15(1):30.
    View in: PubMed
    Score: 0.105
  28. Friedland RP, Shi J, Lamanna JC, Smith MA, Perry G. Prospects for noninvasive imaging of brain amyloid beta in Alzheimer's disease. Ann N Y Acad Sci. 2000 Apr; 903:123-8.
    View in: PubMed
    Score: 0.104
  29. Smith MA, Joseph JA, Perry G. Arson. Tracking the culprit in Alzheimer's disease. Ann N Y Acad Sci. 2000; 924:35-8.
    View in: PubMed
    Score: 0.102
  30. Reyes-Pablo AE, Campa-C?rdoba BB, Luna-Viramontes NI, Ontiveros-Torres M?, Villanueva-Fierro I, Bravo-Mu?oz M, S?enz-Ibarra B, Barbosa O, Guadarrama-Ort?z P, Garc?s-Ram?rez L, de la Cruz F, Harrington CR, Mart?nez-Robles S, Gonz?lez-Ballesteros E, Perry G, Pacheco-Herrero M, Luna-Mu?oz J. National Dementia BioBank: A Strategy for the Diagnosis and Study of Neurodegenerative Diseases in M?xico. J Alzheimers Dis. 2020; 76(3):853-862.
    View in: PubMed
    Score: 0.102
  31. Espay AJ, Vizcarra JA, Marsili L, Lang AE, Simon DK, Merola A, Josephs KA, Fasano A, Morgante F, Savica R, Greenamyre JT, Cambi F, Yamasaki TR, Tanner CM, Gan-Or Z, Litvan I, Mata IF, Zabetian CP, Brundin P, Fernandez HH, Standaert DG, Kauffman MA, Schwarzschild MA, Sardi SP, Sherer T, Perry G, Leverenz JB. Revisiting protein aggregation as pathogenic in sporadic Parkinson and Alzheimer diseases. Neurology. 2019 02 12; 92(7):329-337.
    View in: PubMed
    Score: 0.096
  32. Castellani RJ, Smith M, Bailey K, Perry G, deJong JL. Neuropathology in Consecutive Forensic Consultation Cases with a History of Remote Traumatic Brain Injury. J Alzheimers Dis. 2019; 72(3):683-691.
    View in: PubMed
    Score: 0.095
  33. Smith MA, Perry G. What are the facts and artifacts of the pathogenesis and etiology of Alzheimer disease? J Chem Neuroanat. 1998 Dec; 16(1):35-41.
    View in: PubMed
    Score: 0.095
  34. Perry G, Nunomura A, Lucassen P, Lassmann H, Smith MA. Apoptosis and Alzheimer's disease. Science. 1998 Nov 13; 282(5392):1268-9.
    View in: PubMed
    Score: 0.094
  35. Pinho TS, Correia SC, Perry G, Ambr?sio AF, Moreira PI. Diminished O-GlcNAcylation in Alzheimer's disease is strongly correlated with mitochondrial anomalies. Biochim Biophys Acta Mol Basis Dis. 2019 08 01; 1865(8):2048-2059.
    View in: PubMed
    Score: 0.094
  36. Perry G, Nunomura A, Smith MA. A suicide note from Alzheimer disease neurons? Nat Med. 1998 Aug; 4(8):897-8.
    View in: PubMed
    Score: 0.093
  37. Everett J, Collingwood JF, Tjendana-Tjhin V, Brooks J, Lermyte F, Plascencia-Villa G, Hands-Portman I, Dobson J, Perry G, Telling ND. Nanoscale synchrotron X-ray speciation of iron and calcium compounds in amyloid plaque cores from Alzheimer's disease subjects. Nanoscale. 2018 Jul 05; 10(25):11782-11796.
    View in: PubMed
    Score: 0.092
  38. Jiang S, Nandy P, Wang W, Ma X, Hsia J, Wang C, Wang Z, Niu M, Siedlak SL, Torres S, Fujioka H, Xu Y, Lee HG, Perry G, Liu J, Zhu X. Mfn2 ablation causes an oxidative stress response and eventual neuronal death in the hippocampus and cortex. Mol Neurodegener. 2018 02 01; 13(1):5.
    View in: PubMed
    Score: 0.089
  39. Kelley AR, Perry G, Bach SBH. Characterization of Proteins Present in Isolated Senile Plaques from Alzheimer's Diseased Brains by MALDI-TOF MS with MS/MS. ACS Chem Neurosci. 2018 04 18; 9(4):708-714.
    View in: PubMed
    Score: 0.089
  40. Yan T, Wang L, Gao J, Siedlak SL, Huntley ML, Termsarasab P, Perry G, Chen SG, Wang X. Rab10 Phosphorylation is a Prominent Pathological Feature in Alzheimer's Disease. J Alzheimers Dis. 2018; 63(1):157-165.
    View in: PubMed
    Score: 0.089
  41. Zabel M, Nackenoff A, Kirsch WM, Harrison FE, Perry G, Schrag M. Markers of oxidative damage to lipids, nucleic acids and proteins and antioxidant enzymes activities in Alzheimer's disease brain: A meta-analysis in human pathological specimens. Free Radic Biol Med. 2018 02 01; 115:351-360.
    View in: PubMed
    Score: 0.089
  42. Sayre LM, Zagorski MG, Surewicz WK, Krafft GA, Perry G. Mechanisms of neurotoxicity associated with amyloid beta deposition and the role of free radicals in the pathogenesis of Alzheimer's disease: a critical appraisal. Chem Res Toxicol. 1997 May; 10(5):518-26.
    View in: PubMed
    Score: 0.085
  43. Mondrag?n-Rodr?guez S, Perry G, Pena-Ortega F, Williams S. Tau, Amyloid Beta and Deep Brain Stimulation: Aiming to Restore Cognitive Deficit in Alzheimer's Disease. Curr Alzheimer Res. 2017; 14(1):40-46.
    View in: PubMed
    Score: 0.083
  44. Rueli RH, Torres DJ, Dewing AS, Kiyohara AC, Barayuga SM, Bellinger MT, Uyehara-Lock JH, White LR, Moreira PI, Berry MJ, Perry G, Bellinger FP. Selenoprotein S Reduces Endoplasmic Reticulum Stress-Induced Phosphorylation of Tau: Potential Role in Selenate Mitigation of Tau Pathology. J Alzheimers Dis. 2017; 55(2):749-762.
    View in: PubMed
    Score: 0.083
  45. Smith MA, Sayre LM, Monnier VM, Perry G. Oxidative posttranslational modifications in Alzheimer disease. A possible pathogenic role in the formation of senile plaques and neurofibrillary tangles. Mol Chem Neuropathol. 1996 May-Aug; 28(1-3):41-8.
    View in: PubMed
    Score: 0.079
  46. Castellani RJ, Perry G, Iverson GL. Chronic effects of mild neurotrauma: putting the cart before the horse? J Neuropathol Exp Neurol. 2015 Jun; 74(6):493-9.
    View in: PubMed
    Score: 0.074
  47. Carvalho C, Correia SC, Perry G, Castellani RJ, Moreira PI. Cerebrovascular and mitochondrial abnormalities in Alzheimer's disease: a brief overview. J Neural Transm (Vienna). 2016 Feb; 123(2):107-11.
    View in: PubMed
    Score: 0.073
  48. Petersen RB, Lissemore FM, Appleby B, Aggarwal N, Boyatzis R, Casadesus G, Cummings J, Jack A, Perry G, Safar J, Sajatovic M, Surewicz WK, Wang Y, Whitehouse P, Lerner A. From Neurodegeneration to Brain Health: An Integrated Approach. J Alzheimers Dis. 2015; 46(1):271-83.
    View in: PubMed
    Score: 0.072
  49. Mondrag?n-Rodr?guez S, Perry G, Luna-Mu?oz J, Acevedo-Aquino MC, Williams S. Phosphorylation of tau protein at sites Ser(396-404) is one of the earliest events in Alzheimer's disease and Down syndrome. Neuropathol Appl Neurobiol. 2014 Feb; 40(2):121-35.
    View in: PubMed
    Score: 0.068
  50. Fawver JN, Ghiwot Y, Koola C, Carrera W, Rodriguez-Rivera J, Hernandez C, Dineley KT, Kong Y, Li J, Jhamandas J, Perry G, Murray IV. Islet amyloid polypeptide (IAPP): a second amyloid in Alzheimer's disease. Curr Alzheimer Res. 2014; 11(10):928-40.
    View in: PubMed
    Score: 0.067
  51. Jarero-Basulto JJ, Luna-Mu?oz J, Mena R, Kristofikova Z, Ripova D, Perry G, Binder LI, Garcia-Sierra F. Proteolytic cleavage of polymeric tau protein by caspase-3: implications for Alzheimer disease. J Neuropathol Exp Neurol. 2013 Dec; 72(12):1145-61.
    View in: PubMed
    Score: 0.067
  52. Kalaria RN, Bhatti SU, Lust WD, Perry G. The amyloid precursor protein in ischemic brain injury and chronic hypoperfusion. Ann N Y Acad Sci. 1993 Sep 24; 695:190-3.
    View in: PubMed
    Score: 0.066
  53. DeWitt DA, Silver J, Canning DR, Perry G. Chondroitin sulfate proteoglycans are associated with the lesions of Alzheimer's disease. Exp Neurol. 1993 Jun; 121(2):149-52.
    View in: PubMed
    Score: 0.065
  54. Correia SC, Santos RX, Santos MS, Casadesus G, Lamanna JC, Perry G, Smith MA, Moreira PI. Mitochondrial abnormalities in a streptozotocin-induced rat model of sporadic Alzheimer's disease. Curr Alzheimer Res. 2013 May 01; 10(4):406-19.
    View in: PubMed
    Score: 0.064
  55. Perry G. Neuritic plaques in Alzheimer disease originate from neurofibrillary tangles. Med Hypotheses. 1993 Apr; 40(4):257-8.
    View in: PubMed
    Score: 0.064
  56. Harik SI, Hall AK, Richey P, Andersson L, Lundahl P, Perry G. Ontogeny of the erythroid/HepG2-type glucose transporter (GLUT-1) in the rat nervous system. Brain Res Dev Brain Res. 1993 Mar 19; 72(1):41-9.
    View in: PubMed
    Score: 0.064
  57. Zhu X, Perry G, Smith MA, Wang X. Abnormal mitochondrial dynamics in the pathogenesis of Alzheimer's disease. J Alzheimers Dis. 2013; 33 Suppl 1:S253-62.
    View in: PubMed
    Score: 0.063
  58. Colom LV, Perry G, Kuljis RO. Tackling the elusive challenges relevant to conquering the 100-plus year old problem of Alzheimer's disease. Curr Alzheimer Res. 2013 Jan; 10(1):108-16.
    View in: PubMed
    Score: 0.063
  59. Santos RX, Correia SC, Zhu X, Smith MA, Moreira PI, Castellani RJ, Nunomura A, Perry G. Mitochondrial DNA oxidative damage and repair in aging and Alzheimer's disease. Antioxid Redox Signal. 2013 Jun 20; 18(18):2444-57.
    View in: PubMed
    Score: 0.063
  60. Candeias E, Duarte AI, Carvalho C, Correia SC, Cardoso S, Santos RX, Pl?cido AI, Perry G, Moreira PI. The impairment of insulin signaling in Alzheimer's disease. IUBMB Life. 2012 Dec; 64(12):951-7.
    View in: PubMed
    Score: 0.062
  61. Kalaria RN, Kroon SN, Grahovac I, Perry G. Acetylcholinesterase and its association with heparan sulphate proteoglycans in cortical amyloid deposits of Alzheimer's disease. Neuroscience. 1992 Nov; 51(1):177-84.
    View in: PubMed
    Score: 0.062
  62. Nunomura A, Tamaoki T, Motohashi N, Nakamura M, McKeel DW, Tabaton M, Lee HG, Smith MA, Perry G, Zhu X. The earliest stage of cognitive impairment in transition from normal aging to Alzheimer disease is marked by prominent RNA oxidation in vulnerable neurons. J Neuropathol Exp Neurol. 2012 Mar; 71(3):233-41.
    View in: PubMed
    Score: 0.059
  63. Bonda DJ, Liu G, Men P, Perry G, Smith MA, Zhu X. Nanoparticle delivery of transition-metal chelators to the brain: Oxidative stress will never see it coming! CNS Neurol Disord Drug Targets. 2012 Feb; 11(1):81-5.
    View in: PubMed
    Score: 0.059
  64. Cras P, Perry G. Dementia with argyrophilic grains. Ann Neurol. 1991 Dec; 30(6):853-4.
    View in: PubMed
    Score: 0.058
  65. Zhu X, Castellani RJ, Moreira PI, Aliev G, Shenk JC, Siedlak SL, Harris PLR, Fujioka H, Sayre LM, Szweda PA, Szweda LI, Smith MA, Perry G. Hydroxynonenal-generated crosslinking fluorophore accumulation in Alzheimer disease reveals a dichotomy of protein turnover. Free Radic Biol Med. 2012 Feb 01; 52(3):699-704.
    View in: PubMed
    Score: 0.058
  66. Bonda DJ, Castellani RJ, Zhu X, Nunomura A, Lee HG, Perry G, Smith MA. A novel perspective on tau in Alzheimer's disease. Curr Alzheimer Res. 2011 Sep; 8(6):639-42.
    View in: PubMed
    Score: 0.057
  67. Kalaria RN, Galloway PG, Perry G. Widespread serum amyloid P immunoreactivity in cortical amyloid deposits and the neurofibrillary pathology of Alzheimer's disease and other degenerative disorders. Neuropathol Appl Neurobiol. 1991 Jun; 17(3):189-201.
    View in: PubMed
    Score: 0.056
  68. Correia SC, Santos RX, Perry G, Zhu X, Moreira PI, Smith MA. Insulin-resistant brain state: the culprit in sporadic Alzheimer's disease? Ageing Res Rev. 2011 Apr; 10(2):264-73.
    View in: PubMed
    Score: 0.055
  69. Heath JE, Siedlak SL, Zhu X, Lee HG, Thakur A, Yan R, Perry G, Smith MA, Castellani RJ. Widespread distribution of reticulon-3 in various neurodegenerative diseases. Neuropathology. 2010 Dec; 30(6):574-9.
    View in: PubMed
    Score: 0.054
  70. Moreira PI, Sayre LM, Zhu X, Nunomura A, Smith MA, Perry G. Detection and localization of markers of oxidative stress by in situ methods: application in the study of Alzheimer disease. Methods Mol Biol. 2010; 610:419-34.
    View in: PubMed
    Score: 0.051
  71. Smith MA, Zhu X, Tabaton M, Liu G, McKeel DW, Cohen ML, Wang X, Siedlak SL, Dwyer BE, Hayashi T, Nakamura M, Nunomura A, Perry G. Increased iron and free radical generation in preclinical Alzheimer disease and mild cognitive impairment. J Alzheimers Dis. 2010; 19(1):363-72.
    View in: PubMed
    Score: 0.051
  72. Borghi R, Piccini A, Barini E, Cirmena G, Guglielmotto M, Tamagno E, Fornaro M, Perry G, Smith MA, Garuti A, Tabaton M. Upregulation of presenilin 1 in brains of sporadic, late-onset Alzheimer's disease. J Alzheimers Dis. 2010; 22(3):771-5.
    View in: PubMed
    Score: 0.051
  73. Lee HP, Casadesus G, Zhu X, Lee HG, Perry G, Smith MA, Gustaw-Rothenberg K, Lerner A. All-trans retinoic acid as a novel therapeutic strategy for Alzheimer's disease. Expert Rev Neurother. 2009 Nov; 9(11):1615-21.
    View in: PubMed
    Score: 0.051
  74. Moreira PI, Carvalho C, Zhu X, Smith MA, Perry G. Mitochondrial dysfunction is a trigger of Alzheimer's disease pathophysiology. Biochim Biophys Acta. 2010 Jan; 1802(1):2-10.
    View in: PubMed
    Score: 0.050
  75. Carvalho C, Correia SC, Santos RX, Cardoso S, Moreira PI, Clark TA, Zhu X, Smith MA, Perry G. Role of mitochondrial-mediated signaling pathways in Alzheimer disease and hypoxia. J Bioenerg Biomembr. 2009 Oct; 41(5):433-40.
    View in: PubMed
    Score: 0.050
  76. Dwyer BE, Stone ML, Gorman N, Sinclair PR, Perry G, Smith MA, Zhu X. Heme-a, the heme prosthetic group of cytochrome c oxidase, is increased in Alzheimer's disease. Neurosci Lett. 2009 Sep 25; 461(3):302-5.
    View in: PubMed
    Score: 0.049
  77. Perez M, Santa-Maria I, Gomez de Barreda E, Zhu X, Cuadros R, Cabrero JR, Sanchez-Madrid F, Dawson HN, Vitek MP, Perry G, Smith MA, Avila J. Tau--an inhibitor of deacetylase HDAC6 function. J Neurochem. 2009 Jun; 109(6):1756-66.
    View in: PubMed
    Score: 0.049
  78. Cardoso S, Correia S, Santos RX, Carvalho C, Santos MS, Oliveira CR, Perry G, Smith MA, Zhu X, Moreira PI. Insulin is a two-edged knife on the brain. J Alzheimers Dis. 2009; 18(3):483-507.
    View in: PubMed
    Score: 0.048
  79. Aliev G, Obrenovich ME, Reddy VP, Shenk JC, Moreira PI, Nunomura A, Zhu X, Smith MA, Perry G. Antioxidant therapy in Alzheimer's disease: theory and practice. Mini Rev Med Chem. 2008 Nov; 8(13):1395-406.
    View in: PubMed
    Score: 0.047
  80. Mondrag?n-Rodr?guez S, Basurto-Islas G, Santa-Maria I, Mena R, Binder LI, Avila J, Smith MA, Perry G, Garc?a-Sierra F. Cleavage and conformational changes of tau protein follow phosphorylation during Alzheimer's disease. Int J Exp Pathol. 2008 Apr; 89(2):81-90.
    View in: PubMed
    Score: 0.045
  81. Gonzalez-Cuyar LF, Perry G, Miyajima H, Atwood CS, Riveros-Angel M, Lyons PF, Siedlak SL, Smith MA, Castellani RJ. Redox active iron accumulation in aceruloplasminemia. Neuropathology. 2008 Oct; 28(5):466-71.
    View in: PubMed
    Score: 0.045
  82. Mondrag?n-Rodr?guez S, Mena R, Binder LI, Smith MA, Perry G, Garc?a-Sierra F. Conformational changes and cleavage of tau in Pick bodies parallel the early processing of tau found in Alzheimer pathology. Neuropathol Appl Neurobiol. 2008 Feb; 34(1):62-75.
    View in: PubMed
    Score: 0.044
  83. Perry G, Friedman R, Kang DH, Manetto V, Autilio-Gambetti L, Gambetti P. Antibodies to the neuronal cytoskeleton are elicited by Alzheimer paired helical filament fractions. Brain Res. 1987 Sep 15; 420(2):233-42.
    View in: PubMed
    Score: 0.044
  84. Perry G, Friedman R, Shaw G, Chau V. Ubiquitin is detected in neurofibrillary tangles and senile plaque neurites of Alzheimer disease brains. Proc Natl Acad Sci U S A. 1987 May; 84(9):3033-6.
    View in: PubMed
    Score: 0.042
  85. Zhu X, Avila J, Perry G, Smith MA. Treating the lesions, not the disease. Am J Pathol. 2007 May; 170(5):1457-9.
    View in: PubMed
    Score: 0.042
  86. Bishop GM, Smith MA, LaManna JC, Wilson AC, Perry G, Atwood CS. Iron homeostasis is maintained in the brain, but not the liver, following mild hypoxia. Redox Rep. 2007; 12(6):257-66.
    View in: PubMed
    Score: 0.042
  87. Zhu X, Raina AK, Perry G, Smith MA. Apoptosis in Alzheimer disease: a mathematical improbability. Curr Alzheimer Res. 2006 Sep; 3(4):393-6.
    View in: PubMed
    Score: 0.041
  88. Liu G, Men P, Harris PL, Rolston RK, Perry G, Smith MA. Nanoparticle iron chelators: a new therapeutic approach in Alzheimer disease and other neurologic disorders associated with trace metal imbalance. Neurosci Lett. 2006 Oct 09; 406(3):189-93.
    View in: PubMed
    Score: 0.040
  89. Obrenovich ME, Smith MA, Siedlak SL, Chen SG, de la Torre JC, Perry G, Aliev G. Overexpression of GRK2 in Alzheimer disease and in a chronic hypoperfusion rat model is an early marker of brain mitochondrial lesions. Neurotox Res. 2006 Aug; 10(1):43-56.
    View in: PubMed
    Score: 0.040
  90. Castellani RJ, Lee HG, Zhu X, Nunomura A, Perry G, Smith MA. Neuropathology of Alzheimer disease: pathognomonic but not pathogenic. Acta Neuropathol. 2006 Jun; 111(6):503-9.
    View in: PubMed
    Score: 0.040
  91. Lee HG, Zhu X, Perry G, Smith MA. The fallacy of amyloid and cognition in Alzheimer's disease. Drugs Aging. 2006; 23(2):179.
    View in: PubMed
    Score: 0.039
  92. Castellani RJ, Siedlak SL, Fortino AE, Perry G, Ghetti B, Smith MA. Chitin-like polysaccharides in Alzheimer's disease brains. Curr Alzheimer Res. 2005 Oct; 2(4):419-23.
    View in: PubMed
    Score: 0.038
  93. Zhu X, Smith MA, Perry G, Wang Y, Ross AP, Zhao HW, Lamanna JC, Drew KL. MAPKs are differentially modulated in arctic ground squirrels during hibernation. J Neurosci Res. 2005 Jun 15; 80(6):862-8.
    View in: PubMed
    Score: 0.037
  94. Lee HG, Castellani RJ, Zhu X, Perry G, Smith MA. Amyloid-beta in Alzheimer's disease: the horse or the cart? Pathogenic or protective? Int J Exp Pathol. 2005 Jun; 86(3):133-8.
    View in: PubMed
    Score: 0.037
  95. Ashford JW, Atwood CS, Blass JP, Bowen RL, Finch CE, Iqbal K, Joseph JA, Perry G. What is aging? What is its role in Alzheimer's disease? What can we do about it? J Alzheimers Dis. 2005 Jun; 7(3):247-53; discussion 255-62.
    View in: PubMed
    Score: 0.037
  96. Honda K, Smith MA, Zhu X, Baus D, Merrick WC, Tartakoff AM, Hattier T, Harris PL, Siedlak SL, Fujioka H, Liu Q, Moreira PI, Miller FP, Nunomura A, Shimohama S, Perry G. Ribosomal RNA in Alzheimer disease is oxidized by bound redox-active iron. J Biol Chem. 2005 Jun 03; 280(22):20978-86.
    View in: PubMed
    Score: 0.037
  97. Aliyev A, Seyidova D, Rzayev N, Obrenovich ME, Lamb BT, Chen SG, Smith MA, Perry G, de la Torre JC, Aliev G. Is nitric oxide a key target in the pathogenesis of brain lesions during the development of Alzheimer's disease? Neurol Res. 2004 Jul; 26(5):547-53.
    View in: PubMed
    Score: 0.035
  98. Castellani RJ, Smith MA, Perry G, Friedland RP. Cerebral amyloid angiopathy: major contributor or decorative response to Alzheimer's disease pathogenesis. Neurobiol Aging. 2004 May-Jun; 25(5):599-602; discussion 603-4.
    View in: PubMed
    Score: 0.034
  99. Seyidova D, Aliyev A, Rzayev N, Obrenovich M, Lamb BT, Smith MA, de la Torre JC, Perry G, Aliev G. The role of nitric oxide in the pathogenesis of brain lesions during the development of Alzheimer's disease. In Vivo. 2004 May-Jun; 18(3):325-33.
    View in: PubMed
    Score: 0.034
  100. Everett J, Brooks J, Tjendana Tjhin V, Lermyte F, Hands-Portman I, Plascencia-Villa G, Perry G, Sadler PJ, O'Connor PB, Collingwood JF, Telling ND. Label-Free In Situ Chemical Characterization of Amyloid Plaques in Human Brain Tissues. ACS Chem Neurosci. 2024 04 03; 15(7):1469-1483.
    View in: PubMed
    Score: 0.034
  101. Garc?a-Carlos CA, Basurto-Islas G, Perry G, Mondrag?n-Rodr?guez S. Meta-Analysis in Transgenic Alzheimer's Disease Mouse Models Reveals Opposite Brain Network Effects of Amyloid-? and Phosphorylated Tau Proteins. J Alzheimers Dis. 2024; 99(2):595-607.
    View in: PubMed
    Score: 0.034
  102. Lathe R, Schultek NM, Balin BJ, Ehrlich GD, Auber LA, Perry G, Breitschwerdt EB, Corry DB, Doty RL, Rissman RA, Nara PL, Itzhaki R, Eimer WA, Tanzi RE. Establishment of a consensus protocol to explore the brain pathobiome in patients with mild cognitive impairment and Alzheimer's disease: Research outline and call for collaboration. Alzheimers Dement. 2023 11; 19(11):5209-5231.
    View in: PubMed
    Score: 0.032
  103. Wang W, Zhao F, Lu Y, Siedlak SL, Fujioka H, Feng H, Perry G, Zhu X. Damaged mitochondria coincide with presynaptic vesicle loss and abnormalities in alzheimer's disease brain. Acta Neuropathol Commun. 2023 03 31; 11(1):54.
    View in: PubMed
    Score: 0.032
  104. Hampel H, Hu Y, Hardy J, Blennow K, Chen C, Perry G, Kim SH, Villemagne VL, Aisen P, Vendruscolo M, Iwatsubo T, Masters CL, Cho M, Lannfelt L, Cummings JL, Vergallo A. The amyloid-? pathway in Alzheimer's disease: a plain language summary. Neurodegener Dis Manag. 2023 06; 13(3):141-149.
    View in: PubMed
    Score: 0.032
  105. Perry G, Taddeo MA, Petersen RB, Castellani RJ, Harris PL, Siedlak SL, Cash AD, Liu Q, Nunomura A, Atwood CS, Smith MA. Adventiously-bound redox active iron and copper are at the center of oxidative damage in Alzheimer disease. Biometals. 2003 Mar; 16(1):77-81.
    View in: PubMed
    Score: 0.032
  106. Atwood CS, Perry G, Smith MA. Cerebral hemorrhage and amyloid-beta. Science. 2003 Feb 14; 299(5609):1014; author reply 1014.
    View in: PubMed
    Score: 0.032
  107. Atwood CS, Bishop GM, Perry G, Smith MA. Amyloid-beta: a vascular sealant that protects against hemorrhage? J Neurosci Res. 2002 Nov 01; 70(3):356.
    View in: PubMed
    Score: 0.031
  108. Castellani R, Hirai K, Aliev G, Drew KL, Nunomura A, Takeda A, Cash AD, Obrenovich ME, Perry G, Smith MA. Role of mitochondrial dysfunction in Alzheimer's disease. J Neurosci Res. 2002 Nov 01; 70(3):357-60.
    View in: PubMed
    Score: 0.031
  109. Smith MA, Casadesus G, Joseph JA, Perry G. Amyloid-beta and tau serve antioxidant functions in the aging and Alzheimer brain. Free Radic Biol Med. 2002 Nov 01; 33(9):1194-9.
    View in: PubMed
    Score: 0.031
  110. Takata K, Kitamura Y, Kakimura J, Shibagaki K, Taniguchi T, Gebicke-Haerter PJ, Smith MA, Perry G, Shimohama S. Possible protective mechanisms of heme oxygenase-1 in the brain. Ann N Y Acad Sci. 2002 Nov; 977:501-6.
    View in: PubMed
    Score: 0.031
  111. Shi J, Perry G, Berridge MS, Aliev G, Siedlak SL, Smith MA, LaManna JC, Friedland RP. Labeling of cerebral amyloid beta deposits in vivo using intranasal basic fibroblast growth factor and serum amyloid P component in mice. J Nucl Med. 2002 Aug; 43(8):1044-51.
    View in: PubMed
    Score: 0.031
  112. Clapp-Lilly KL, Smith MA, Perry G, Harris PL, Zhu X, Drew KL, Duffy LK. Melatonin exhibits antioxidant properties in a mouse brain slice model of excitotoxicity. Int J Circumpolar Health. 2002 Feb; 61(1):32-40.
    View in: PubMed
    Score: 0.030
  113. Aliev G, Smith MA, Seyidov D, Neal ML, Lamb BT, Nunomura A, Gasimov EK, Vinters HV, Perry G, LaManna JC, Friedland RP. The role of oxidative stress in the pathophysiology of cerebrovascular lesions in Alzheimer's disease. Brain Pathol. 2002 Jan; 12(1):21-35.
    View in: PubMed
    Score: 0.029
  114. Wang Q, Davis PB, Qi X, Chen SG, Gurney ME, Perry G, Doraiswamy PM, Xu R. Gut-microbiota-microglia-brain interactions in Alzheimer's disease: knowledge-based, multi-dimensional characterization. Alzheimers Res Ther. 2021 10 20; 13(1):177.
    View in: PubMed
    Score: 0.029
  115. Zhu X, Rottkamp CA, Hartzler A, Sun Z, Takeda A, Boux H, Shimohama S, Perry G, Smith MA. Activation of MKK6, an upstream activator of p38, in Alzheimer's disease. J Neurochem. 2001 Oct; 79(2):311-8.
    View in: PubMed
    Score: 0.029
  116. Clapp-Lilly KL, Smith MA, Perry G, Duffy LK. Melatonin reduces interleukin secretion in amyloid-beta stressed mouse brain slices. Chem Biol Interact. 2001 Mar 14; 134(1):101-7.
    View in: PubMed
    Score: 0.028
  117. Wong BS, Liu T, Li R, Pan T, Petersen RB, Smith MA, Gambetti P, Perry G, Manson JC, Brown DR, Sy MS. Increased levels of oxidative stress markers detected in the brains of mice devoid of prion protein. J Neurochem. 2001 Jan; 76(2):565-72.
    View in: PubMed
    Score: 0.027
  118. Mah AL, Perry G, Smith MA, Monteiro MJ. Identification of ubiquilin, a novel presenilin interactor that increases presenilin protein accumulation. J Cell Biol. 2000 Nov 13; 151(4):847-62.
    View in: PubMed
    Score: 0.027
  119. Shimohama S, Tanino H, Kawakami N, Okamura N, Kodama H, Yamaguchi T, Hayakawa T, Nunomura A, Chiba S, Perry G, Smith MA, Fujimoto S. Activation of NADPH oxidase in Alzheimer's disease brains. Biochem Biophys Res Commun. 2000 Jun 24; 273(1):5-9.
    View in: PubMed
    Score: 0.026
  120. Gonz?lez-S?nchez M, Bartolome F, Antequera D, Puertas-Mart?n V, Gonz?lez P, G?mez-Grande A, Llamas-Velasco S, Herrero-San Mart?n A, P?rez-Mart?nez D, Villarejo-Galende A, Atienza M, Palomar-Bonet M, Cantero JL, Perry G, Orive G, Iba?ez B, Bueno H, Fuster V, Carro E. Decreased salivary lactoferrin levels are specific to Alzheimer's disease. EBioMedicine. 2020 Jul; 57:102834.
    View in: PubMed
    Score: 0.026
  121. Smith MA, Nunomura A, Zhu X, Takeda A, Perry G. Metabolic, metallic, and mitotic sources of oxidative stress in Alzheimer disease. Antioxid Redox Signal. 2000; 2(3):413-20.
    View in: PubMed
    Score: 0.026
  122. Gao J, Wang L, Gao C, Arakawa H, Perry G, Wang X. TDP-43 inhibitory peptide alleviates neurodegeneration and memory loss in an APP transgenic mouse model for Alzheimer's disease. Biochim Biophys Acta Mol Basis Dis. 2020 01 01; 1866(1):165580.
    View in: PubMed
    Score: 0.025
  123. Perry G, Roder H, Nunomura A, Takeda A, Friedlich AL, Zhu X, Raina AK, Holbrook N, Siedlak SL, Harris PL, Smith MA. Activation of neuronal extracellular receptor kinase (ERK) in Alzheimer disease links oxidative stress to abnormal phosphorylation. Neuroreport. 1999 Aug 02; 10(11):2411-5.
    View in: PubMed
    Score: 0.025
  124. Raina AK, Takeda A, Nunomura A, Perry G, Smith MA. Genetic evidence for oxidative stress in Alzheimer's disease. Neuroreport. 1999 Apr 26; 10(6):1355-7.
    View in: PubMed
    Score: 0.024
  125. Wang C, Zhao F, Shen K, Wang W, Siedlak SL, Lee HG, Phelix CF, Perry G, Shen L, Tang B, Yan R, Zhu X. The sterol regulatory element-binding protein 2 is dysregulated by tau alterations in Alzheimer disease. Brain Pathol. 2019 07; 29(4):530-543.
    View in: PubMed
    Score: 0.024
  126. Tripathy A, Shade A, Erskine B, Bailey K, Grande A, deLong JJ, Perry G, Castellani RJ. No Evidence of Increased Chronic Traumatic Encephalopathy Pathology or Neurodegenerative Proteinopathy in Former Military Service Members: A Preliminary Study. J Alzheimers Dis. 2019; 67(4):1277-1289.
    View in: PubMed
    Score: 0.024
  127. Hattori N, Kitagawa K, Higashida T, Yagyu K, Shimohama S, Wataya T, Perry G, Smith MA, Inagaki C. CI-ATPase and Na+/K(+)-ATPase activities in Alzheimer's disease brains. Neurosci Lett. 1998 Oct 02; 254(3):141-4.
    View in: PubMed
    Score: 0.023
  128. Odetti P, Angelini G, Dapino D, Zaccheo D, Garibaldi S, Dagna-Bricarelli F, Piombo G, Perry G, Smith M, Traverso N, Tabaton M. Early glycoxidation damage in brains from Down's syndrome. Biochem Biophys Res Commun. 1998 Feb 24; 243(3):849-51.
    View in: PubMed
    Score: 0.022
  129. DeWitt DA, Perry G, Cohen M, Doller C, Silver J. Astrocytes regulate microglial phagocytosis of senile plaque cores of Alzheimer's disease. Exp Neurol. 1998 Feb; 149(2):329-40.
    View in: PubMed
    Score: 0.022
  130. Wang W, Yin J, Ma X, Zhao F, Siedlak SL, Wang Z, Torres S, Fujioka H, Xu Y, Perry G, Zhu X. Inhibition of mitochondrial fragmentation protects against Alzheimer's disease in rodent model. Hum Mol Genet. 2017 11 01; 26(21):4118-4131.
    View in: PubMed
    Score: 0.022
  131. Mart?n-Maestro P, Gargini R, Garc?a E, Perry G, Avila J, Garc?a-Escudero V. Slower Dynamics and Aged Mitochondria in Sporadic Alzheimer's Disease. Oxid Med Cell Longev. 2017; 2017:9302761.
    View in: PubMed
    Score: 0.022
  132. Salomon RG, Subbanagounder G, O'Neil J, Kaur K, Smith MA, Hoff HF, Perry G, Monnier VM. Levuglandin E2-protein adducts in human plasma and vasculature. Chem Res Toxicol. 1997 May; 10(5):536-45.
    View in: PubMed
    Score: 0.021
  133. Tabaton M, Perry G, Smith M, Vitek M, Angelini G, Dapino D, Garibaldi S, Zaccheo D, Odetti P. Is amyloid beta-protein glycated in Alzheimer's disease? Neuroreport. 1997 Mar 03; 8(4):907-9.
    View in: PubMed
    Score: 0.021
  134. Greenberg BD, Savage MJ, Howland DS, Ali SM, Siedlak SL, Perry G, Siman R, Scott RW. APP transgenesis: approaches toward the development of animal models for Alzheimer disease neuropathology. Neurobiol Aging. 1996 Mar-Apr; 17(2):153-71.
    View in: PubMed
    Score: 0.020
  135. Itzhaki RF, Lathe R, Balin BJ, Ball MJ, Bearer EL, Braak H, Bullido MJ, Carter C, Clerici M, Cosby SL, Del Tredici K, Field H, Fulop T, Grassi C, Griffin WS, Haas J, Hudson AP, Kamer AR, Kell DB, Licastro F, Letenneur L, L?vheim H, Mancuso R, Miklossy J, Otth C, Palamara AT, Perry G, Preston C, Pretorius E, Strandberg T, Tabet N, Taylor-Robinson SD, Whittum-Hudson JA. Microbes and Alzheimer's Disease. J Alzheimers Dis. 2016; 51(4):979-84.
    View in: PubMed
    Score: 0.019
  136. Mart?n-Maestro P, Gargini R, Perry G, Avila J, Garc?a-Escudero V. PARK2 enhancement is able to compensate mitophagy alterations found in sporadic Alzheimer's disease. Hum Mol Genet. 2016 Feb 15; 25(4):792-806.
    View in: PubMed
    Score: 0.019
  137. Sharoar MG, Shi Q, Ge Y, He W, Hu X, Perry G, Zhu X, Yan R. Dysfunctional tubular endoplasmic reticulum constitutes a pathological feature of Alzheimer's disease. Mol Psychiatry. 2016 09; 21(9):1263-71.
    View in: PubMed
    Score: 0.019
  138. Castellani R, Smith MA, Richey PL, Kalaria R, Gambetti P, Perry G. Evidence for oxidative stress in Pick disease and corticobasal degeneration. Brain Res. 1995 Oct 23; 696(1-2):268-71.
    View in: PubMed
    Score: 0.019
  139. Premkumar DR, Smith MA, Richey PL, Petersen RB, Castellani R, Kutty RK, Wiggert B, Perry G, Kalaria RN. Induction of heme oxygenase-1 mRNA and protein in neocortex and cerebral vessels in Alzheimer's disease. J Neurochem. 1995 Sep; 65(3):1399-402.
    View in: PubMed
    Score: 0.019
  140. Gerenu G, Liu K, Chojnacki JE, Saathoff JM, Mart?nez-Mart?n P, Perry G, Zhu X, Lee HG, Zhang S. Curcumin/melatonin hybrid 5-(4-hydroxy-phenyl)-3-oxo-pentanoic acid [2-(5-methoxy-1H-indol-3-yl)-ethyl]-amide ameliorates AD-like pathology in the APP/PS1 mouse model. ACS Chem Neurosci. 2015 Aug 19; 6(8):1393-1399.
    View in: PubMed
    Score: 0.018
  141. Luna-Mu?oz J, Perry G, Guevara J. Ra?l Mena: 1953-2014. J Alzheimers Dis. 2015; 45(2):325-7.
    View in: PubMed
    Score: 0.018
  142. Correia SC, Perry G, Castellani R, Moreira PI. Is exercise-in-a-bottle likely to proffer new insights into Alzheimer's disease? J Neurochem. 2013 Oct; 127(1):4-6.
    View in: PubMed
    Score: 0.017
  143. Shimohama S, Fujimoto S, Tresser N, Richey P, Perry G, Whitehouse PJ, Homma Y, Takenawa T, Taniguchi T, Suenaga T, et al. Aberrant phosphoinositide metabolism in Alzheimer's disease. Ann N Y Acad Sci. 1993 Sep 24; 695:46-9.
    View in: PubMed
    Score: 0.017
  144. Kalaria RN, Golde T, Kroon SN, Perry G. Serine protease inhibitor antithrombin III and its messenger RNA in the pathogenesis of Alzheimer's disease. Am J Pathol. 1993 Sep; 143(3):886-93.
    View in: PubMed
    Score: 0.016
  145. Kalaria RN, Bhatti SU, Palatinsky EA, Pennington DH, Shelton ER, Chan HW, Perry G, Lust WD. Accumulation of the beta amyloid precursor protein at sites of ischemic injury in rat brain. Neuroreport. 1993 Feb; 4(2):211-4.
    View in: PubMed
    Score: 0.016
  146. Ciss? S, Perry G, Lacoste-Royal G, Cabana T, Gauvreau D. Immunochemical identification of ubiquitin and heat-shock proteins in corpora amylacea from normal aged and Alzheimer's disease brains. Acta Neuropathol. 1993; 85(3):233-40.
    View in: PubMed
    Score: 0.016
  147. Williams WM, Castellani RJ, Weinberg A, Perry G, Smith MA. Do ?-defensins and other antimicrobial peptides play a role in neuroimmune function and neurodegeneration? ScientificWorldJournal. 2012; 2012:905785.
    View in: PubMed
    Score: 0.015
  148. Harik SI, Kalaria RN, Andersson L, Lundahl P, Perry G. Immunocytochemical localization of the erythroid glucose transporter: abundance in tissues with barrier functions. J Neurosci. 1990 Dec; 10(12):3862-72.
    View in: PubMed
    Score: 0.014
  149. Castellani RJ, Nugent SL, Morrison AL, Zhu X, Lee HG, Harris PL, Bajic V, Sharma HS, Chen SG, Oettgen P, Perry G, Smith MA. CD3 in Lewy pathology: does the abnormal recall of neurodevelopmental processes underlie Parkinson's disease. J Neural Transm (Vienna). 2011 Jan; 118(1):23-6.
    View in: PubMed
    Score: 0.014
  150. Cras P, Kawai M, Siedlak S, Mulvihill P, Gambetti P, Lowery D, Gonzalez-DeWhitt P, Greenberg B, Perry G. Neuronal and microglial involvement in beta-amyloid protein deposition in Alzheimer's disease. Am J Pathol. 1990 Aug; 137(2):241-6.
    View in: PubMed
    Score: 0.013
  151. Zou WQ, Puoti G, Xiao X, Yuan J, Qing L, Cali I, Shimoji M, Langeveld JP, Castellani R, Notari S, Crain B, Schmidt RE, Geschwind M, Dearmond SJ, Cairns NJ, Dickson D, Honig L, Torres JM, Mastrianni J, Capellari S, Giaccone G, Belay ED, Schonberger LB, Cohen M, Perry G, Kong Q, Parchi P, Tagliavini F, Gambetti P. Variably protease-sensitive prionopathy: a new sporadic disease of the prion protein. Ann Neurol. 2010 Aug; 68(2):162-72.
    View in: PubMed
    Score: 0.013
  152. Liu G, Men P, Perry G, Smith MA. Nanoparticle and iron chelators as a potential novel Alzheimer therapy. Methods Mol Biol. 2010; 610:123-44.
    View in: PubMed
    Score: 0.013
  153. Dwyer BE, Smith MA, Richardson SL, Perry G, Zhu X. Down-regulation of aminolevulinate synthase, the rate-limiting enzyme for heme biosynthesis in Alzheimer's disease. Neurosci Lett. 2009 Aug 28; 460(2):180-4.
    View in: PubMed
    Score: 0.012
  154. Liu G, Men P, Kudo W, Perry G, Smith MA. Nanoparticle-chelator conjugates as inhibitors of amyloid-beta aggregation and neurotoxicity: a novel therapeutic approach for Alzheimer disease. Neurosci Lett. 2009 May 22; 455(3):187-90.
    View in: PubMed
    Score: 0.012
  155. Rajendran R, Minqin R, Ynsa MD, Casadesus G, Smith MA, Perry G, Halliwell B, Watt F. A novel approach to the identification and quantitative elemental analysis of amyloid deposits--insights into the pathology of Alzheimer's disease. Biochem Biophys Res Commun. 2009 Apr 24; 382(1):91-5.
    View in: PubMed
    Score: 0.012
  156. Guglielmotto M, Aragno M, Autelli R, Giliberto L, Novo E, Colombatto S, Danni O, Parola M, Smith MA, Perry G, Tamagno E, Tabaton M. The up-regulation of BACE1 mediated by hypoxia and ischemic injury: role of oxidative stress and HIF1alpha. J Neurochem. 2009 Feb; 108(4):1045-56.
    View in: PubMed
    Score: 0.012
  157. Kalaria RN, Gravina SA, Schmidley JW, Perry G, Harik SI. The glucose transporter of the human brain and blood-brain barrier. Ann Neurol. 1988 Dec; 24(6):757-64.
    View in: PubMed
    Score: 0.012
  158. Manetto V, Sternberger NH, Perry G, Sternberger LA, Gambetti P. Phosphorylation of neurofilaments is altered in amyotrophic lateral sclerosis. J Neuropathol Exp Neurol. 1988 Nov; 47(6):642-53.
    View in: PubMed
    Score: 0.012
  159. Tabaton M, Whitehouse PJ, Perry G, Davies P, Autilio-Gambetti L, Gambetti P. Alz 50 recognizes abnormal filaments in Alzheimer's disease and progressive supranuclear palsy. Ann Neurol. 1988 Sep; 24(3):407-13.
    View in: PubMed
    Score: 0.012
  160. Manetto V, Perry G, Tabaton M, Mulvihill P, Fried VA, Smith HT, Gambetti P, Autilio-Gambetti L. Ubiquitin is associated with abnormal cytoplasmic filaments characteristic of neurodegenerative diseases. Proc Natl Acad Sci U S A. 1988 Jun; 85(12):4501-5.
    View in: PubMed
    Score: 0.011
  161. Su B, Wang X, Drew KL, Perry G, Smith MA, Zhu X. Physiological regulation of tau phosphorylation during hibernation. J Neurochem. 2008 Jun 01; 105(6):2098-108.
    View in: PubMed
    Score: 0.011
  162. Petersen RB, Nunomura A, Lee HG, Casadesus G, Perry G, Smith MA, Zhu X. Signal transduction cascades associated with oxidative stress in Alzheimer's disease. J Alzheimers Dis. 2007 May; 11(2):143-52.
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    Score: 0.011
  163. Gonzalez-Cuyar LF, Hunter B, Harris PL, Perry G, Smith MA, Castellani RJ. Cerebrotendinous xanthomatosis: case report with evidence of oxidative stress. Redox Rep. 2007; 12(3):119-24.
    View in: PubMed
    Score: 0.010
  164. Sparks DL, Friedland R, Petanceska S, Schreurs BG, Shi J, Perry G, Smith MA, Sharma A, Derosa S, Ziolkowski C, Stankovic G. Trace copper levels in the drinking water, but not zinc or aluminum influence CNS Alzheimer-like pathology. J Nutr Health Aging. 2006 Jul-Aug; 10(4):247-54.
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    Score: 0.010
  165. Castellani RJ, Lee HG, Perry G, Smith MA. Antioxidant protection and neurodegenerative disease: the role of amyloid-beta and tau. Am J Alzheimers Dis Other Demen. 2006 Mar-Apr; 21(2):126-30.
    View in: PubMed
    Score: 0.010
  166. Perry G, Selkoe DJ, Block BR, Stewart D, Autilio-Gambetti L, Gambetti P. Electron microscopic localization of Alzheimer neurofibrillary tangle components recognized by an antiserum to paired helical filaments. J Neuropathol Exp Neurol. 1986 Mar; 45(2):161-8.
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    Score: 0.010
  167. Santa-Mar?a I, Hern?ndez F, Smith MA, Perry G, Avila J, Moreno FJ. Neurotoxic dopamine quinone facilitates the assembly of tau into fibrillar polymers. Mol Cell Biochem. 2005 Oct; 278(1-2):203-12.
    View in: PubMed
    Score: 0.010
  168. Webber KM, Casadesus G, Marlatt MW, Perry G, Hamlin CR, Atwood CS, Bowen RL, Smith MA. Estrogen bows to a new master: the role of gonadotropins in Alzheimer pathogenesis. Ann N Y Acad Sci. 2005 Jun; 1052:201-9.
    View in: PubMed
    Score: 0.009
  169. Zhu X, Perry G, Smith MA. Insulin signaling, diabetes mellitus and risk of Alzheimer disease. J Alzheimers Dis. 2005 Feb; 7(1):81-4.
    View in: PubMed
    Score: 0.009
  170. Aliyev A, Chen SG, Seyidova D, Smith MA, Perry G, de la Torre J, Aliev G. Mitochondria DNA deletions in atherosclerotic hypoperfused brain microvessels as a primary target for the development of Alzheimer's disease. J Neurol Sci. 2005 Mar 15; 229-230:285-92.
    View in: PubMed
    Score: 0.009
  171. Zhu X, Smith MA, Perry G, Aliev G. Mitochondrial failures in Alzheimer's disease. Am J Alzheimers Dis Other Demen. 2004 Nov-Dec; 19(6):345-52.
    View in: PubMed
    Score: 0.009
  172. Dwyer BE, Raina AK, Perry G, Smith MA. Homocysteine and Alzheimer's disease: a modifiable risk? Free Radic Biol Med. 2004 Jun 01; 36(11):1471-5.
    View in: PubMed
    Score: 0.009
  173. Kang SC, Brown DR, Whiteman M, Li R, Pan T, Perry G, Wisniewski T, Sy MS, Wong BS. Prion protein is ubiquitinated after developing protease resistance in the brains of scrapie-infected mice. J Pathol. 2004 May; 203(1):603-8.
    View in: PubMed
    Score: 0.009
  174. Bowen RL, Verdile G, Liu T, Parlow AF, Perry G, Smith MA, Martins RN, Atwood CS. Luteinizing hormone, a reproductive regulator that modulates the processing of amyloid-beta precursor protein and amyloid-beta deposition. J Biol Chem. 2004 May 07; 279(19):20539-45.
    View in: PubMed
    Score: 0.008
  175. Kitamura Y, Tsuchiya D, Takata K, Shibagaki K, Taniguchi T, Smith MA, Perry G, Miki H, Takenawa T, Shimohama S. Possible involvement of Wiskott-Aldrich syndrome protein family in aberrant neuronal sprouting in Alzheimer's disease. Neurosci Lett. 2003 Aug 07; 346(3):149-52.
    View in: PubMed
    Score: 0.008
  176. Takata K, Kitamura Y, Kakimura J, Shibagaki K, Tsuchiya D, Taniguchi T, Smith MA, Perry G, Shimohama S. Role of high mobility group protein-1 (HMG1) in amyloid-beta homeostasis. Biochem Biophys Res Commun. 2003 Feb 14; 301(3):699-703.
    View in: PubMed
    Score: 0.008
  177. Raina AK, Zhu X, Shimohama S, Perry G, Smith MA. Tipping the apoptotic balance in Alzheimer's disease: the abortosis concept. Cell Biochem Biophys. 2003; 39(3):249-55.
    View in: PubMed
    Score: 0.008
  178. Obrenovich ME, Joseph JA, Atwood CS, Perry G, Smith MA. Amyloid-beta: a (life) preserver for the brain. Neurobiol Aging. 2002 Nov-Dec; 23(6):1097-9.
    View in: PubMed
    Score: 0.008
  179. Kakimura J, Kitamura Y, Takata K, Tsuchiya D, Taniguchi T, Gebicke-Haerter PJ, Smith MA, Perry G, Shimohama S. Possible involvement of ER chaperone Grp78 on reduced formation of amyloid-beta deposits. Ann N Y Acad Sci. 2002 Nov; 977:327-32.
    View in: PubMed
    Score: 0.008
  180. Lee HG, Zhu X, Ghanbari HA, Ogawa O, Raina AK, O'Neill MJ, Perry G, Smith MA. Differential regulation of glutamate receptors in Alzheimer's disease. Neurosignals. 2002 Sep-Oct; 11(5):282-92.
    View in: PubMed
    Score: 0.008
  181. Pappolla MA, Smith MA, Bryant-Thomas T, Bazan N, Petanceska S, Perry G, Thal LJ, Sano M, Refolo LM. Cholesterol, oxidative stress, and Alzheimer's disease: expanding the horizons of pathogenesis. Free Radic Biol Med. 2002 Jul 15; 33(2):173-81.
    View in: PubMed
    Score: 0.008
  182. Guentchev M, Siedlak SL, Jarius C, Tagliavini F, Castellani RJ, Perry G, Smith MA, Budka H. Oxidative damage to nucleic acids in human prion disease. Neurobiol Dis. 2002 Apr; 9(3):275-81.
    View in: PubMed
    Score: 0.007
  183. Nunomura A, Perry G, Aliev G, Hirai K, Takeda A, Balraj EK, Jones PK, Ghanbari H, Wataya T, Shimohama S, Chiba S, Atwood CS, Petersen RB, Smith MA. Oxidative damage is the earliest event in Alzheimer disease. J Neuropathol Exp Neurol. 2001 Aug; 60(8):759-67.
    View in: PubMed
    Score: 0.007
  184. Pappolla MA, Omar RA, Chyan YJ, Ghiso J, Hsiao K, Bozner P, Perry G, Smith MA, Cruz-Sanchez F. Induction of NADPH cytochrome P450 reductase by the Alzheimer beta-protein. Amyloid as a "foreign body". J Neurochem. 2001 Jul; 78(1):121-8.
    View in: PubMed
    Score: 0.007
  185. Cuajungco MP, Goldstein LE, Nunomura A, Smith MA, Lim JT, Atwood CS, Huang X, Farrag YW, Perry G, Bush AI. Evidence that the beta-amyloid plaques of Alzheimer's disease represent the redox-silencing and entombment of abeta by zinc. J Biol Chem. 2000 Jun 30; 275(26):19439-42.
    View in: PubMed
    Score: 0.007
  186. Nunomura A, Perry G, Pappolla MA, Wade R, Hirai K, Chiba S, Smith MA. RNA oxidation is a prominent feature of vulnerable neurons in Alzheimer's disease. J Neurosci. 1999 Mar 15; 19(6):1959-64.
    View in: PubMed
    Score: 0.006
  187. Pappolla MA, Chyan YJ, Omar RA, Hsiao K, Perry G, Smith MA, Bozner P. Evidence of oxidative stress and in vivo neurotoxicity of beta-amyloid in a transgenic mouse model of Alzheimer's disease: a chronic oxidative paradigm for testing antioxidant therapies in vivo. Am J Pathol. 1998 Apr; 152(4):871-7.
    View in: PubMed
    Score: 0.006
  188. Sayre LM, Zelasko DA, Harris PL, Perry G, Salomon RG, Smith MA. 4-Hydroxynonenal-derived advanced lipid peroxidation end products are increased in Alzheimer's disease. J Neurochem. 1997 May; 68(5):2092-7.
    View in: PubMed
    Score: 0.005
  189. Shimohama S, Fujimoto S, Matsushima H, Takenawa T, Taniguchi T, Perry G, Whitehouse PJ, Kimura J. Alteration of phospholipase C-delta protein level and specific activity in Alzheimer's disease. J Neurochem. 1995 Jun; 64(6):2629-34.
    View in: PubMed
    Score: 0.005
  190. Aikawa M, Brown A, Smith CD, Tegoshi T, Howard RJ, Hasler TH, Ito Y, Perry G, Collins WE, Webster K. A primate model for human cerebral malaria: Plasmodium coatneyi-infected rhesus monkeys. Am J Trop Med Hyg. 1992 Apr; 46(4):391-7.
    View in: PubMed
    Score: 0.004
  191. Palmert MR, Siedlak SL, Podlisny MB, Greenberg B, Shelton ER, Chan HW, Usiak M, Selkoe DJ, Perry G, Younkin SG. Soluble derivatives of the beta amyloid protein precursor of Alzheimer's disease are labeled by antisera to the beta amyloid protein. Biochem Biophys Res Commun. 1989 Nov 30; 165(1):182-8.
    View in: PubMed
    Score: 0.003
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
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