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Connection

Thomas Forsthuber to Mice

This is a "connection" page, showing publications Thomas Forsthuber has written about Mice.
Connection Strength

1.510
  1. Asmis R, Medrano MT, Chase Huizar C, Griffith WP, Forsthuber TG. Dietary Supplementation with 23-Hydroxy Ursolic Acid Reduces the Severity and Incidence of Acute Experimental Autoimmune Encephalomyelitis (EAE) in a Murine Model of Multiple Sclerosis. Nutrients. 2024 Jan 25; 16(3).
    View in: PubMed
    Score: 0.114
  2. Chase Huizar C, Ji N, Reddick R, Ostroff GR, Forsthuber TG. Glucan particles as a novel adjuvant for the induction of experimental autoimmune encephalomyelitis. Cell Immunol. 2021 08; 366:104383.
    View in: PubMed
    Score: 0.094
  3. Raphael I, Gomez-Rivera F, Raphael RA, Robinson RR, Nalawade S, Forsthuber TG. TNFR2 limits proinflammatory astrocyte functions during EAE induced by pathogenic DR2b-restricted T cells. JCI Insight. 2019 12 19; 4(24).
    View in: PubMed
    Score: 0.086
  4. Ji N, Forsthuber TG. ELISPOT Techniques. Methods Mol Biol. 2016; 1304:63-71.
    View in: PubMed
    Score: 0.065
  5. Sosa RA, Murphey C, Ji N, Cardona AE, Forsthuber TG. The kinetics of myelin antigen uptake by myeloid cells in the central nervous system during experimental autoimmune encephalomyelitis. J Immunol. 2013 Dec 15; 191(12):5848-57.
    View in: PubMed
    Score: 0.056
  6. Ji N, Somanaboeina A, Dixit A, Kawamura K, Hayward NJ, Self C, Olson GL, Forsthuber TG. Small molecule inhibitor of antigen binding and presentation by HLA-DR2b as a therapeutic strategy for the treatment of multiple sclerosis. J Immunol. 2013 Nov 15; 191(10):5074-84.
    View in: PubMed
    Score: 0.056
  7. Ji N, Sosa RA, Forsthuber TG. More than just a T-box: the role of T-bet as a possible biomarker and therapeutic target in autoimmune diseases. Immunotherapy. 2011 Mar; 3(3):435-41.
    View in: PubMed
    Score: 0.047
  8. Ji N, Rao N, Guentzel NM, Arulanandam BP, Forsthuber TG. Anaphylaxis and mortality induced by treatment of mice with anti-VLA-4 antibody and pertussis toxin. J Immunol. 2011 Mar 01; 186(5):2750-6.
    View in: PubMed
    Score: 0.046
  9. Murphey C, Chang S, Zhang X, Arulanandam B, Forsthuber TG. Induction of polyclonal CD8+ T cell activation and effector function by Pertussis toxin. Cell Immunol. 2011; 267(1):50-5.
    View in: PubMed
    Score: 0.046
  10. Hofstetter HH, Forsthuber TG. Kinetics of IL-17- and interferon-gamma-producing PLPp-specific CD4 T cells in EAE induced by coinjection of PLPp/IFA with pertussis toxin in SJL mice. Neurosci Lett. 2010 Jun 07; 476(3):150-5.
    View in: PubMed
    Score: 0.044
  11. Smirnova IS, Chang S, Forsthuber TG. Prosurvival and proapoptotic functions of ERK1/2 activation in murine thymocytes in vitro. Cell Immunol. 2010; 261(1):29-36.
    View in: PubMed
    Score: 0.042
  12. Kawamura K, McLaughlin KA, Weissert R, Forsthuber TG. Myelin-reactive type B T cells and T cells specific for low-affinity MHC-binding myelin peptides escape tolerance in HLA-DR transgenic mice. J Immunol. 2008 Sep 01; 181(5):3202-11.
    View in: PubMed
    Score: 0.039
  13. Denkinger CM, Denkinger MD, Forsthuber TG. Pertussis toxin-induced cytokine differentiation and clonal expansion of T cells is mediated predominantly via costimulation. Cell Immunol. 2007 Mar; 246(1):46-54.
    View in: PubMed
    Score: 0.036
  14. Hofstetter HH, Kovalovsky A, Shive CL, Lehmann PV, Forsthuber TG. Neonatal induction of myelin-specific Th1/Th17 immunity does not result in experimental autoimmune encephalomyelitis and can protect against the disease in adulthood. J Neuroimmunol. 2007 Jul; 187(1-2):20-30.
    View in: PubMed
    Score: 0.036
  15. Kort JJ, Kawamura K, Fugger L, Weissert R, Forsthuber TG. Efficient presentation of myelin oligodendrocyte glycoprotein peptides but not protein by astrocytes from HLA-DR2 and HLA-DR4 transgenic mice. J Neuroimmunol. 2006 Apr; 173(1-2):23-34.
    View in: PubMed
    Score: 0.033
  16. Nekrasova T, Shive C, Gao Y, Kawamura K, Guardia R, Landreth G, Forsthuber TG. ERK1-deficient mice show normal T cell effector function and are highly susceptible to experimental autoimmune encephalomyelitis. J Immunol. 2005 Aug 15; 175(4):2374-80.
    View in: PubMed
    Score: 0.032
  17. Klehmet J, Shive C, Guardia-Wolff R, Petersen I, Spack EG, Boehm BO, Weissert R, Forsthuber TG. T cell epitope spreading to myelin oligodendrocyte glycoprotein in HLA-DR4 transgenic mice during experimental autoimmune encephalomyelitis. Clin Immunol. 2004 Apr; 111(1):53-60.
    View in: PubMed
    Score: 0.029
  18. Denkinger M, Shive CL, Pantenburg B, Forsthuber TG. Suramin has adjuvant properties and promotes expansion of antigen-specific Th1 and Th2 cells in vivo. Int Immunopharmacol. 2004 Jan; 4(1):15-24.
    View in: PubMed
    Score: 0.028
  19. Denkinger CM, Denkinger M, Kort JJ, Metz C, Forsthuber TG. In vivo blockade of macrophage migration inhibitory factor ameliorates acute experimental autoimmune encephalomyelitis by impairing the homing of encephalitogenic T cells to the central nervous system. J Immunol. 2003 Feb 01; 170(3):1274-82.
    View in: PubMed
    Score: 0.027
  20. Hofstetter HH, Shive CL, Forsthuber TG. Pertussis toxin modulates the immune response to neuroantigens injected in incomplete Freund's adjuvant: induction of Th1 cells and experimental autoimmune encephalomyelitis in the presence of high frequencies of Th2 cells. J Immunol. 2002 Jul 01; 169(1):117-25.
    View in: PubMed
    Score: 0.026
  21. Ebhardt MB, Shive CL, Guardia R, Gapin L, Boehm BO, Forsthuber TG. Immunological adjuvants efficiently induce antigen-specific T cell responses in old mice: implications for vaccine adjuvant development in aged individuals. Cell Immunol. 2002 Jan; 215(1):87-97.
    View in: PubMed
    Score: 0.025
  22. Forsthuber TG, Shive CL, Wienhold W, de Graaf K, Spack EG, Sublett R, Melms A, Kort J, Racke MK, Weissert R. T cell epitopes of human myelin oligodendrocyte glycoprotein identified in HLA-DR4 (DRB1*0401) transgenic mice are encephalitogenic and are presented by human B cells. J Immunol. 2001 Dec 15; 167(12):7119-25.
    View in: PubMed
    Score: 0.025
  23. Porritt RA, Chase Huizar C, Dick EJ, Kumar S, Escalona R, Gomez AC, Marek-Iannucci S, Noval Rivas M, Patterson J, Forsthuber TG, Arditi M, Gorelik M. Inhibition of IL-6 in the LCWE Mouse Model of Kawasaki Disease Inhibits Acute Phase Reactant Serum Amyloid A but Fails to Attenuate Vasculitis. Front Immunol. 2021; 12:630196.
    View in: PubMed
    Score: 0.023
  24. Manouchehri N, Hussain RZ, Cravens PD, Esaulova E, Artyomov MN, Edelson BT, Wu GF, Cross AH, Doelger R, Loof N, Eagar TN, Forsthuber TG, Calvier L, Herz J, St?ve O. CD11c+CD88+CD317+ myeloid cells are critical mediators of persistent CNS autoimmunity. Proc Natl Acad Sci U S A. 2021 04 06; 118(14).
    View in: PubMed
    Score: 0.023
  25. Shive CL, Hofstetter H, Arredondo L, Shaw C, Forsthuber TG. The enhanced antigen-specific production of cytokines induced by pertussis toxin is due to clonal expansion of T cells and not to altered effector functions of long-term memory cells. Eur J Immunol. 2000 Aug; 30(8):2422-31.
    View in: PubMed
    Score: 0.022
  26. Manouchehri N, Hussain RZ, Cravens PD, Doelger R, Greenberg BM, Okuda DT, Forsthuber TG, Eagar TN, St?ve O. Limitations of cell-lineage-specific non-dynamic gene recombination in CD11c.Cre+ITGA4fl/fl mice. J Neuroimmunol. 2020 07 15; 344:577245.
    View in: PubMed
    Score: 0.022
  27. Lehmann PV, Targoni OS, Forsthuber TG. Shifting T-cell activation thresholds in autoimmunity and determinant spreading. Immunol Rev. 1998 Aug; 164:53-61.
    View in: PubMed
    Score: 0.019
  28. Salekin S, Bari MG, Raphael I, Forsthuber TG, Zhang JM. Early response index: a statistic to discover potential early stage disease biomarkers. BMC Bioinformatics. 2017 Jun 23; 18(1):313.
    View in: PubMed
    Score: 0.018
  29. Bloom J, Metz C, Nalawade S, Casabar J, Cheng KF, He M, Sherry B, Coleman T, Forsthuber T, Al-Abed Y. Identification of Iguratimod as an Inhibitor of Macrophage Migration Inhibitory Factor (MIF) with Steroid-sparing Potential. J Biol Chem. 2016 Dec 16; 291(51):26502-26514.
    View in: PubMed
    Score: 0.017
  30. Cunningham AL, Guentzel MN, Yu JJ, Hung CY, Forsthuber TG, Navara CS, Yagita H, Williams IR, Klose KE, Eaves-Pyles TD, Arulanandam BP. M-Cells Contribute to the Entry of an Oral Vaccine but Are Not Essential for the Subsequent Induction of Protective Immunity against Francisella tularensis. PLoS One. 2016; 11(4):e0153402.
    View in: PubMed
    Score: 0.017
  31. Forsthuber T, Yip HC, Lehmann PV. Induction of TH1 and TH2 immunity in neonatal mice. Science. 1996 Mar 22; 271(5256):1728-30.
    View in: PubMed
    Score: 0.017
  32. Raphael I, Mahesula S, Purkar A, Black D, Catala A, Gelfond JA, Forsthuber TG, Haskins WE. Microwave & magnetic (M2) proteomics reveals CNS-specific protein expression waves that precede clinical symptoms of experimental autoimmune encephalomyelitis. Sci Rep. 2014 Sep 03; 4:6210.
    View in: PubMed
    Score: 0.015
  33. Li W, Murthy AK, Lanka GK, Chetty SL, Yu JJ, Chambers JP, Zhong G, Forsthuber TG, Guentzel MN, Arulanandam BP. A T cell epitope-based vaccine protects against chlamydial infection in HLA-DR4 transgenic mice. Vaccine. 2013 Nov 19; 31(48):5722-8.
    View in: PubMed
    Score: 0.014
  34. Garcia JA, Pino PA, Mizutani M, Cardona SM, Charo IF, Ransohoff RM, Forsthuber TG, Cardona AE. Regulation of adaptive immunity by the fractalkine receptor during autoimmune inflammation. J Immunol. 2013 Aug 01; 191(3):1063-72.
    View in: PubMed
    Score: 0.014
  35. Mahesula S, Raphael I, Raghunathan R, Kalsaria K, Kotagiri V, Purkar AB, Anjanappa M, Shah D, Pericherla V, Jadhav YL, Gelfond JA, Forsthuber TG, Haskins WE. Immunoenrichment microwave and magnetic proteomics for quantifying CD47 in the experimental autoimmune encephalomyelitis model of multiple sclerosis. Electrophoresis. 2012 Dec; 33(24):3820-9.
    View in: PubMed
    Score: 0.013
  36. Raphael I, Mahesula S, Kalsaria K, Kotagiri V, Purkar AB, Anjanappa M, Shah D, Pericherla V, Jadhav YL, Raghunathan R, Vaynberg M, Noriega D, Grimaldo NH, Wenk C, Gelfond JA, Forsthuber TG, Haskins WE. Microwave and magnetic (M(2) ) proteomics of the experimental autoimmune encephalomyelitis animal model of multiple sclerosis. Electrophoresis. 2012 Dec; 33(24):3810-9.
    View in: PubMed
    Score: 0.013
  37. Arellano B, Hussain R, Zacharias T, Yoon J, David C, Zein S, Steinman L, Forsthuber T, Greenberg BM, Lambracht-Washington D, Ritchie AM, Bennett JL, St?ve O. Human aquaporin 4281-300 is the immunodominant linear determinant in the context of HLA-DRB1*03:01: relevance for diagnosing and monitoring patients with neuromyelitis optica. Arch Neurol. 2012 Sep; 69(9):1125-31.
    View in: PubMed
    Score: 0.013
  38. Rodriguez AR, Yu JJ, Guentzel MN, Navara CS, Klose KE, Forsthuber TG, Chambers JP, Berton MT, Arulanandam BP. Mast cell TLR2 signaling is crucial for effective killing of Francisella tularensis. J Immunol. 2012 Jun 01; 188(11):5604-11.
    View in: PubMed
    Score: 0.013
  39. Thathiah P, Sanapala S, Rodriguez AR, Yu JJ, Murthy AK, Guentzel MN, Forsthuber TG, Chambers JP, Arulanandam BP. Non-FceR bearing mast cells secrete sufficient interleukin-4 to control Francisella tularensis replication within macrophages. Cytokine. 2011 Aug; 55(2):211-20.
    View in: PubMed
    Score: 0.012
  40. Murthy AK, Li W, Chaganty BK, Kamalakaran S, Guentzel MN, Seshu J, Forsthuber TG, Zhong G, Arulanandam BP. Tumor necrosis factor alpha production from CD8+ T cells mediates oviduct pathological sequelae following primary genital Chlamydia muridarum infection. Infect Immun. 2011 Jul; 79(7):2928-35.
    View in: PubMed
    Score: 0.012
  41. Cantor JR, Yoo TH, Dixit A, Iverson BL, Forsthuber TG, Georgiou G. Therapeutic enzyme deimmunization by combinatorial T-cell epitope removal using neutral drift. Proc Natl Acad Sci U S A. 2011 Jan 25; 108(4):1272-7.
    View in: PubMed
    Score: 0.012
  42. Rodriguez AR, Yu JJ, Murthy AK, Guentzel MN, Klose KE, Forsthuber TG, Chambers JP, Berton MT, Arulanandam BP. Mast cell/IL-4 control of Francisella tularensis replication and host cell death is associated with increased ATP production and phagosomal acidification. Mucosal Immunol. 2011 Mar; 4(2):217-26.
    View in: PubMed
    Score: 0.011
  43. Li W, Murthy AK, Guentzel MN, Chambers JP, Forsthuber TG, Seshu J, Zhong G, Arulanandam BP. Immunization with a combination of integral chlamydial antigens and a defined secreted protein induces robust immunity against genital chlamydial challenge. Infect Immun. 2010 Sep; 78(9):3942-9.
    View in: PubMed
    Score: 0.011
  44. Jupelli M, Selby DM, Guentzel MN, Chambers JP, Forsthuber TG, Zhong G, Murthy AK, Arulanandam BP. The contribution of interleukin-12/interferon-gamma axis in protection against neonatal pulmonary Chlamydia muridarum challenge. J Interferon Cytokine Res. 2010 Jun; 30(6):407-15.
    View in: PubMed
    Score: 0.011
  45. Yu JJ, Goluguri T, Guentzel MN, Chambers JP, Murthy AK, Klose KE, Forsthuber TG, Arulanandam BP. Francisella tularensis T-cell antigen identification using humanized HLA-DR4 transgenic mice. Clin Vaccine Immunol. 2010 Feb; 17(2):215-22.
    View in: PubMed
    Score: 0.011
  46. Ketavarapu JM, Rodriguez AR, Yu JJ, Cong Y, Murthy AK, Forsthuber TG, Guentzel MN, Klose KE, Berton MT, Arulanandam BP. Mast cells inhibit intramacrophage Francisella tularensis replication via contact and secreted products including IL-4. Proc Natl Acad Sci U S A. 2008 Jul 08; 105(27):9313-8.
    View in: PubMed
    Score: 0.010
  47. Li W, Murthy AK, Guentzel MN, Seshu J, Forsthuber TG, Zhong G, Arulanandam BP. Antigen-specific CD4+ T cells produce sufficient IFN-gamma to mediate robust protective immunity against genital Chlamydia muridarum infection. J Immunol. 2008 Mar 01; 180(5):3375-82.
    View in: PubMed
    Score: 0.009
  48. Jane-wit D, Altuntas CZ, Monti J, Johnson JM, Forsthuber TG, Tuohy VK. Sex-defined T-cell responses to cardiac self determine differential outcomes of murine dilated cardiomyopathy. Am J Pathol. 2008 Jan; 172(1):11-21.
    View in: PubMed
    Score: 0.009
  49. Hofstetter HH, Grau C, Buttmann M, Forsthuber TG, Gaupp S, Toyka KV, Gold R. The PLPp-specific T-cell population promoted by pertussis toxin is characterized by high frequencies of IL-17-producing cells. Cytokine. 2007 Oct; 40(1):35-43.
    View in: PubMed
    Score: 0.009
  50. Murthy AK, Cong Y, Murphey C, Guentzel MN, Forsthuber TG, Zhong G, Arulanandam BP. Chlamydial protease-like activity factor induces protective immunity against genital chlamydial infection in transgenic mice that express the human HLA-DR4 allele. Infect Immun. 2006 Dec; 74(12):6722-9.
    View in: PubMed
    Score: 0.009
  51. Macaubas C, Wahlstrom J, Galv?o da Silva AP, Forsthuber TG, S?nderstrup G, Kwok WW, DeKruyff RH, Umetsu DT. Allergen-specific MHC class II tetramer+ cells are detectable in allergic, but not in nonallergic, individuals. J Immunol. 2006 Apr 15; 176(8):5069-77.
    View in: PubMed
    Score: 0.008
  52. Hofstetter HH, Karulin AY, Forsthuber TG, Ott PA, Tary-Lehmann M, Lehmann PV. The cytokine signature of MOG-specific CD4 cells in the EAE of C57BL/6 mice. J Neuroimmunol. 2005 Dec 30; 170(1-2):105-14.
    View in: PubMed
    Score: 0.008
  53. Hofstetter HH, Targoni OS, Karulin AY, Forsthuber TG, Tary-Lehmann M, Lehmann PV. Does the frequency and avidity spectrum of the neuroantigen-specific T cells in the blood mirror the autoimmune process in the central nervous system of mice undergoing experimental allergic encephalomyelitis? J Immunol. 2005 Apr 15; 174(8):4598-605.
    View in: PubMed
    Score: 0.008
  54. Fingerle-Rowson G, Petrenko O, Metz CN, Forsthuber TG, Mitchell R, Huss R, Moll U, M?ller W, Bucala R. The p53-dependent effects of macrophage migration inhibitory factor revealed by gene targeting. Proc Natl Acad Sci U S A. 2003 Aug 05; 100(16):9354-9.
    View in: PubMed
    Score: 0.007
  55. Hofstetter HH, Sewell DL, Liu F, Sandor M, Forsthuber T, Lehmann PV, Fabry Z. Autoreactive T cells promote post-traumatic healing in the central nervous system. J Neuroimmunol. 2003 Jan; 134(1-2):25-34.
    View in: PubMed
    Score: 0.007
  56. Targoni OS, Baus J, Hofstetter HH, Hesse MD, Karulin AY, Boehm BO, Forsthuber TG, Lehmann PV. Frequencies of neuroantigen-specific T cells in the central nervous system versus the immune periphery during the course of experimental allergic encephalomyelitis. J Immunol. 2001 Apr 01; 166(7):4757-64.
    View in: PubMed
    Score: 0.006
  57. Benson JM, Campbell KA, Guan Z, Gienapp IE, Stuckman SS, Forsthuber T, Whitacre CC. T-cell activation and receptor downmodulation precede deletion induced by mucosally administered antigen. J Clin Invest. 2000 Oct; 106(8):1031-8.
    View in: PubMed
    Score: 0.006
  58. Lovett-Racke AE, Smith ME, Arredondo LR, Bittner PS, Ratts RB, Shive CL, Forsthuber TG, Racke MK. Developmentally regulated gene expression of Th2 cytokines in the brain. Brain Res. 2000 Jul 07; 870(1-2):27-35.
    View in: PubMed
    Score: 0.006
  59. Heeger PS, Forsthuber T, Shive C, Biekert E, Genain C, Hofstetter HH, Karulin A, Lehmann PV. Revisiting tolerance induced by autoantigen in incomplete Freund's adjuvant. J Immunol. 2000 Jun 01; 164(11):5771-81.
    View in: PubMed
    Score: 0.006
  60. Yip HC, Karulin AY, Tary-Lehmann M, Hesse MD, Radeke H, Heeger PS, Trezza RP, Heinzel FP, Forsthuber T, Lehmann PV. Adjuvant-guided type-1 and type-2 immunity: infectious/noninfectious dichotomy defines the class of response. J Immunol. 1999 Apr 01; 162(7):3942-9.
    View in: PubMed
    Score: 0.005
  61. Gross DM, Forsthuber T, Tary-Lehmann M, Etling C, Ito K, Nagy ZA, Field JA, Steere AC, Huber BT. Identification of LFA-1 as a candidate autoantigen in treatment-resistant Lyme arthritis. Science. 1998 Jul 31; 281(5377):703-6.
    View in: PubMed
    Score: 0.005
  62. Tian J, Atkinson MA, Clare-Salzler M, Herschenfeld A, Forsthuber T, Lehmann PV, Kaufman DL. Nasal administration of glutamate decarboxylase (GAD65) peptides induces Th2 responses and prevents murine insulin-dependent diabetes. J Exp Med. 1996 Apr 01; 183(4):1561-7.
    View in: PubMed
    Score: 0.004
  63. Kaufman DL, Clare-Salzler M, Tian J, Forsthuber T, Ting GS, Robinson P, Atkinson MA, Sercarz EE, Tobin AJ, Lehmann PV. Spontaneous loss of T-cell tolerance to glutamic acid decarboxylase in murine insulin-dependent diabetes. Nature. 1993 Nov 04; 366(6450):69-72.
    View in: PubMed
    Score: 0.003
  64. Lehmann PV, Forsthuber T, Miller A, Sercarz EE. Spreading of T-cell autoimmunity to cryptic determinants of an autoantigen. Nature. 1992 Jul 09; 358(6382):155-7.
    View in: PubMed
    Score: 0.003
  65. Schmidt H, Forsthuber T, B?hring HJ, M?ller CA. Differential expression of the HLA-B7 and the HLA-A2 gene in transfected mouse L(tk-) cells after stimulation by mouse interferon. Immunobiology. 1987 Jan; 174(1):51-66.
    View in: PubMed
    Score: 0.002
Connection Strength

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