Hugues Ouellet to Mycobacterium tuberculosis
This is a "connection" page, showing publications Hugues Ouellet has written about Mycobacterium tuberculosis.
Connection Strength
3.300
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Ouellet H, Chow ED, Guan S, Cox JS, Burlingame AL, de Montellano PR. Genetic and mass spectrometric tools for elucidating the physiological function(s) of cytochrome P450 enzymes from Mycobacterium tuberculosis. Methods Mol Biol. 2013; 987:79-94.
Score: 0.402
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Ouellet H, Johnston JB, de Montellano PR. Cholesterol catabolism as a therapeutic target in Mycobacterium tuberculosis. Trends Microbiol. 2011 Nov; 19(11):530-9.
Score: 0.367
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Ouellet H, Kells PM, Ortiz de Montellano PR, Podust LM. Reverse type I inhibitor of Mycobacterium tuberculosis CYP125A1. Bioorg Med Chem Lett. 2011 Jan 01; 21(1):332-7.
Score: 0.346
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Ouellet H, Guan S, Johnston JB, Chow ED, Kells PM, Burlingame AL, Cox JS, Podust LM, de Montellano PR. Mycobacterium tuberculosis CYP125A1, a steroid C27 monooxygenase that detoxifies intracellularly generated cholest-4-en-3-one. Mol Microbiol. 2010 Aug; 77(3):730-42.
Score: 0.336
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Ouellet H, Johnston JB, Ortiz de Montellano PR. The Mycobacterium tuberculosis cytochrome P450 system. Arch Biochem Biophys. 2010 Jan 01; 493(1):82-95.
Score: 0.316
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Ouellet H, Lang J, Couture M, Ortiz de Montellano PR. Reaction of Mycobacterium tuberculosis cytochrome P450 enzymes with nitric oxide. Biochemistry. 2009 Feb 10; 48(5):863-72.
Score: 0.307
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Ouellet H, Podust LM, de Montellano PR. Mycobacterium tuberculosis CYP130: crystal structure, biophysical characterization, and interactions with antifungal azole drugs. J Biol Chem. 2008 Feb 22; 283(8):5069-80.
Score: 0.283
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Ouellet H, Juszczak L, Dantsker D, Samuni U, Ouellet YH, Savard PY, Wittenberg JB, Wittenberg BA, Friedman JM, Guertin M. Reactions of Mycobacterium tuberculosis truncated hemoglobin O with ligands reveal a novel ligand-inclusive hydrogen bond network. Biochemistry. 2003 May 20; 42(19):5764-74.
Score: 0.206
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Aguilera J, Karki CB, Li L, Vazquez Reyes S, Estevao I, Grajeda BI, Zhang Q, Arico CD, Ouellet H, Sun J. Na-Acetylation of the virulence factor EsxA is required for mycobacterial cytosolic translocation and virulence. J Biol Chem. 2020 04 24; 295(17):5785-5794.
Score: 0.165
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Zhang Q, Wang D, Jiang G, Liu W, Deng Q, Li X, Qian W, Ouellet H, Sun J. EsxA membrane-permeabilizing activity plays a key role in mycobacterial cytosolic translocation and virulence: effects of single-residue mutations at glutamine 5. Sci Rep. 2016 09 07; 6:32618.
Score: 0.130
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Johnston JB, Ouellet H, Ortiz de Montellano PR. Functional redundancy of steroid C26-monooxygenase activity in Mycobacterium tuberculosis revealed by biochemical and genetic analyses. J Biol Chem. 2010 Nov 19; 285(47):36352-60.
Score: 0.086
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Podust LM, Ouellet H, von Kries JP, de Montellano PR. Interaction of Mycobacterium tuberculosis CYP130 with heterocyclic arylamines. J Biol Chem. 2009 Sep 11; 284(37):25211-9.
Score: 0.079
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Podust LM, von Kries JP, Eddine AN, Kim Y, Yermalitskaya LV, Kuehne R, Ouellet H, Warrier T, Altek?ster M, Lee JS, Rademann J, Oschkinat H, Kaufmann SH, Waterman MR. Small-molecule scaffolds for CYP51 inhibitors identified by high-throughput screening and defined by X-ray crystallography. Antimicrob Agents Chemother. 2007 Nov; 51(11):3915-23.
Score: 0.069
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Dantsker D, Samuni U, Ouellet Y, Wittenberg BA, Wittenberg JB, Milani M, Bolognesi M, Guertin M, Friedman JM. Viscosity-dependent relaxation significantly modulates the kinetics of CO recombination in the truncated hemoglobin TrHbN from Mycobacterium tuberculosis. J Biol Chem. 2004 Sep 10; 279(37):38844-53.
Score: 0.056
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Mukai M, Ouellet Y, Ouellet H, Guertin M, Yeh SR. NO binding induced conformational changes in a truncated hemoglobin from Mycobacterium tuberculosis. Biochemistry. 2004 Mar 16; 43(10):2764-70.
Score: 0.055
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Mukai M, Savard PY, Ouellet H, Guertin M, Yeh SR. Unique ligand-protein interactions in a new truncated hemoglobin from Mycobacterium tuberculosis. Biochemistry. 2002 Mar 26; 41(12):3897-905.
Score: 0.048
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Sivaramakrishnan S, Ouellet H, Matsumura H, Guan S, Mo?nne-Loccoz P, Burlingame AL, Ortiz de Montellano PR. Proximal ligand electron donation and reactivity of the cytochrome P450 ferric-peroxo anion. J Am Chem Soc. 2012 Apr 18; 134(15):6673-84.
Score: 0.024
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Milani M, Ouellet Y, Ouellet H, Guertin M, Boffi A, Antonini G, Bocedi A, Mattu M, Bolognesi M, Ascenzi P. Cyanide binding to truncated hemoglobins: a crystallographic and kinetic study. Biochemistry. 2004 May 11; 43(18):5213-21.
Score: 0.014
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Milani M, Pesce A, Ouellet H, Guertin M, Bolognesi M. Truncated hemoglobins and nitric oxide action. IUBMB Life. 2003 Oct-Nov; 55(10-11):623-7.
Score: 0.013