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Connection

Renato J. Aguilera to Humans

This is a "connection" page, showing publications Renato J. Aguilera has written about Humans.
Connection Strength

0.779
  1. Borrego EA, Guerena CD, Schiaffino Bustamante AY, Gutierrez DA, Valenzuela CA, Betancourt AP, Varela-Ramirez A, Aguilera RJ. A Novel Pyrazole Exhibits Potent Anticancer Cytotoxicity via Apoptosis, Cell Cycle Arrest, and the Inhibition of Tubulin Polymerization in Triple-Negative Breast Cancer Cells. Cells. 2024 Jul 20; 13(14).
    View in: PubMed
    Score: 0.046
  2. Swain RM, Sanchez A, Gutierrez DA, Varela-Ramirez A, Aguilera RJ. Thiophene derivative inflicts cytotoxicity via an intrinsic apoptotic pathway on human acute lymphoblastic leukemia cells. PLoS One. 2023; 18(12):e0295441.
    View in: PubMed
    Score: 0.044
  3. Aguilera RJ. A virus changed my life. Mol Biol Cell. 2022 12 01; 33(14):ae2.
    View in: PubMed
    Score: 0.041
  4. Swain RM, Contreras L, Varela-Ramirez A, Hossain M, Das U, Valenzuela CA, Penichet ML, Dimmock JR, Aguilera RJ. Two novel piperidones induce apoptosis and antiproliferative effects on human prostate and lymphoma cancer cell lines. Invest New Drugs. 2022 Oct; 40(5):905-921.
    View in: PubMed
    Score: 0.040
  5. Gutierrez DA, Contreras L, Villanueva PJ, Borrego EA, Mor?n-Santiba?ez K, Hess JD, DeJesus R, Larragoity M, Betancourt AP, Mohl JE, Robles-Escajeda E, Begum K, Roy S, Kirken RA, Varela-Ramirez A, Aguilera RJ. Identification of a Potent Cytotoxic Pyrazole with Anti-Breast Cancer Activity That Alters Multiple Pathways. Cells. 2022 01 12; 11(2).
    View in: PubMed
    Score: 0.038
  6. Contreras L, Medina S, Schiaffino Bustamante AY, Borrego EA, Valenzuela CA, Das U, Karki SS, Dimmock JR, Aguilera RJ. Three novel piperidones exhibit tumor-selective cytotoxicity on leukemia cells via protein degradation and stress-mediated mechanisms. Pharmacol Rep. 2022 Feb; 74(1):159-174.
    View in: PubMed
    Score: 0.037
  7. Gutierrez DA, DeJesus RE, Contreras L, Rodriguez-Palomares IA, Villanueva PJ, Balderrama KS, Monterroza L, Larragoity M, Varela-Ramirez A, Aguilera RJ. A new pyridazinone exhibits potent cytotoxicity on human cancer cells via apoptosis and poly-ubiquitinated protein accumulation. Cell Biol Toxicol. 2019 12; 35(6):503-519.
    View in: PubMed
    Score: 0.032
  8. Villanueva PJ, Martinez A, Baca ST, DeJesus RE, Larragoity M, Contreras L, Gutierrez DA, Varela-Ramirez A, Aguilera RJ. Pyronaridine exerts potent cytotoxicity on human breast and hematological cancer cells through induction of apoptosis. PLoS One. 2018; 13(11):e0206467.
    View in: PubMed
    Score: 0.031
  9. Contreras L, Calderon RI, Varela-Ramirez A, Zhang HY, Quan Y, Das U, Dimmock JR, Skouta R, Aguilera RJ. Induction of apoptosis via proteasome inhibition in leukemia/lymphoma cells by two potent piperidones. Cell Oncol (Dordr). 2018 Dec; 41(6):623-636.
    View in: PubMed
    Score: 0.030
  10. Robles-Escajeda E, Das U, Ortega NM, Parra K, Francia G, Dimmock JR, Varela-Ramirez A, Aguilera RJ. A novel curcumin-like dienone induces apoptosis in triple-negative breast cancer cells. Cell Oncol (Dordr). 2016 Jun; 39(3):265-77.
    View in: PubMed
    Score: 0.026
  11. Robles-Escajeda E, Mart?nez A, Varela-Ramirez A, S?nchez-Delgado RA, Aguilera RJ. Analysis of the cytotoxic effects of ruthenium-ketoconazole and ruthenium-clotrimazole complexes on cancer cells. Cell Biol Toxicol. 2013 Dec; 29(6):431-43.
    View in: PubMed
    Score: 0.022
  12. Aguilera RJ. Issues on diversity, training, and mentorship of young scientists: an interview. Mol Biol Cell. 2012 Jun; 23(12):2237-9.
    View in: PubMed
    Score: 0.020
  13. Varela-Ramirez A, Costanzo M, Carrasco YP, Pannell KH, Aguilera RJ. Cytotoxic effects of two organotin compounds and their mode of inflicting cell death on four mammalian cancer cells. Cell Biol Toxicol. 2011 Jun; 27(3):159-68.
    View in: PubMed
    Score: 0.018
  14. Mart?nez A, Rajapakse CS, S?nchez-Delgado RA, Varela-Ramirez A, Lema C, Aguilera RJ. Arene-Ru(II)-chloroquine complexes interact with DNA, induce apoptosis on human lymphoid cell lines and display low toxicity to normal mammalian cells. J Inorg Biochem. 2010 Sep; 104(9):967-77.
    View in: PubMed
    Score: 0.017
  15. Montoya J, Varela-Ramirez A, Shanmugasundram M, Martinez LE, Primm TP, Aguilera RJ. Tandem screening of toxic compounds on GFP-labeled bacteria and cancer cells in microtiter plates. Biochem Biophys Res Commun. 2005 Sep 23; 335(2):367-72.
    View in: PubMed
    Score: 0.012
  16. Varela-Ramirez A, Mejia A, Garcia D, Bader J, Aguilera RJ. HIV infection and risk behavior of Hispanic farm workers at the west Texas-Mexico border. Ethn Dis. 2005; 15(4 Suppl 5):S5-92-6.
    View in: PubMed
    Score: 0.012
  17. Montoya J, Varela-Ramirez A, Estrada A, Martinez LE, Garza K, Aguilera RJ. A fluorescence-based rapid screening assay for cytotoxic compounds. Biochem Biophys Res Commun. 2004 Dec 24; 325(4):1517-23.
    View in: PubMed
    Score: 0.012
  18. ElMorsy SM, Gutierrez DA, Valdez S, Kumar J, Aguilera RJ, Noufal M, Sarma H, Chinnam S, Narayan M. Graphene acid quantum dots: A highly active multifunctional carbon nano material that intervene in the trajectory towards neurodegeneration. J Colloid Interface Sci. 2024 Sep 15; 670:357-363.
    View in: PubMed
    Score: 0.011
  19. Evans CJ, Aguilera RJ. DNase II: genes, enzymes and function. Gene. 2003 Dec 11; 322:1-15.
    View in: PubMed
    Score: 0.011
  20. Jain PM, Gutierrez DA, Kumar S, Aguilera RJ, Karki SS. Synthesis of Novel Pyrazole-Oxindole Conjugates with Cytotoxicity in Human Cancer Cells via Apoptosis. Chem Biodivers. 2023 Sep; 20(9):e202300843.
    View in: PubMed
    Score: 0.011
  21. Tchounwou PB, Malouhi M, Ofili EO, Fern?ndez-Repollet E, Sarpong DF, Yanagihara R, Aguilera RJ, Ay?n C, Chen X, Dasmahapatra A, Gao S, Hinton CV, Holt R, Kolesnichenko V, Powell MD, Merchant F, Redda KK, Roche-Lima A, Shikuma CM, Stevens JJ, Torres JA, Trotter RT, Wachira J, Wang P, Wells KJ, White J, Wu Y. Research Infrastructure Core Facilities at Research Centers in Minority Institutions: Part I-Research Resources Management, Operation, and Best Practices. Int J Environ Res Public Health. 2022 12 17; 19(24).
    View in: PubMed
    Score: 0.010
  22. Ma Y, Qiu C, Wang B, Zhang X, Wang X, Aguilera RJ, Zhang JY. Autoantibody against Tumor-Associated Antigens as Diagnostic Biomarkers in Hispanic Patients with Hepatocellular Carcinoma. Cells. 2022 10 14; 11(20).
    View in: PubMed
    Score: 0.010
  23. Chhikara A, Roayapalley PK, Sakagami H, Amano S, Satoh K, Uesawa Y, Das U, Das S, Borrego EA, Guerena CD, Hernandez CR, Aguilera RJ, Dimmock JR. Novel Unsymmetric 3,5-Bis(benzylidene)-4-piperidones That Display Tumor-Selective Toxicity. Molecules. 2022 Oct 09; 27(19).
    View in: PubMed
    Score: 0.010
  24. Huda MN, Deaguero IG, Borrego EA, Kumar R, Islam T, Afrin H, Varela-Ramirez A, Aguilera RJ, Tanner EEL, Nurunnabi M. Ionic liquid-mediated delivery of a BCL-2 inhibitor for topical treatment of skin melanoma. J Control Release. 2022 09; 349:783-795.
    View in: PubMed
    Score: 0.010
  25. Evans CJ, Merriam JR, Aguilera RJ. Drosophila acid DNase is a homolog of mammalian DNase II. Gene. 2002 Jul 24; 295(1):61-70.
    View in: PubMed
    Score: 0.010
  26. Roayapalley PK, Dimmock JR, Contreras L, Balderrama KS, Aguilera RJ, Sakagami H, Amano S, Sharma RK, Das U. Design, Synthesis and Tumour-Selective Toxicity of Novel 1-[3-{3,5-Bis(benzylidene)-4-oxo-1-piperidino}-3-oxopropyl]-4-piperidone Oximes and Related Quaternary Ammonium Salts. Molecules. 2021 Nov 25; 26(23).
    View in: PubMed
    Score: 0.010
  27. Tilekar K, Hess JD, Upadhyay N, Bianco AL, Schweipert M, Laghezza A, Loiodice F, Meyer-Almes FJ, Aguilera RJ, Lavecchia A, C S R. Thiazolidinedione "Magic Bullets" Simultaneously Targeting PPAR? and HDACs: Design, Synthesis, and Investigations of their In Vitro and In Vivo Antitumor Effects. J Med Chem. 2021 05 27; 64(10):6949-6971.
    View in: PubMed
    Score: 0.009
  28. Choodamani B, Cano Hernandez KG, Kumar S, Tony AM, Schiaffino Bustamante AY, Aguilera RJ, Schols D, Gopi Mohan C, Karki SS. Synthesis, Molecular Docking and Preliminary Antileukemic Activity of 4-Methoxybenzyl Derivatives Bearing Imidazo[2,1-b][1,3,4]thiadiazole. Chem Biodivers. 2021 Feb; 18(2):e2000800.
    View in: PubMed
    Score: 0.009
  29. Nakamura-Bencomo S, Gutierrez DA, Robles-Escajeda E, Iglesias-Figueroa B, Siqueiros-Cend?n TS, Espinoza-S?nchez EA, Ar?valo-Gallegos S, Aguilera RJ, Rasc?n-Cruz Q, Varela-Ramirez A. Recombinant human lactoferrin carrying humanized glycosylation exhibits antileukemia selective cytotoxicity, microfilament disruption, cell cycle arrest, and apoptosis activities. Invest New Drugs. 2021 04; 39(2):400-415.
    View in: PubMed
    Score: 0.009
  30. Philipovskiy A, Dwivedi AK, Gamez R, McCallum R, Mukherjee D, Nahleh Z, Aguilera RJ, Gaur S. Association between tumor mutation profile and clinical outcomes among Hispanic Latina women with triple-negative breast cancer. PLoS One. 2020; 15(9):e0238262.
    View in: PubMed
    Score: 0.009
  31. Lyon CJ, Evans CJ, Bill BR, Otsuka AJ, Aguilera RJ. The C. elegans apoptotic nuclease NUC-1 is related in sequence and activity to mammalian DNase II. Gene. 2000 Jul 11; 252(1-2):147-54.
    View in: PubMed
    Score: 0.009
  32. Tilekar K, Upadhyay N, Hess JD, Macias LH, Mrowka P, Aguilera RJ, Meyer-Almes FJ, Iancu CV, Choe JY, Ramaa CS. Structure guided design and synthesis of furyl thiazolidinedione derivatives as inhibitors of GLUT 1 and GLUT 4, and evaluation of their anti-leukemic potential. Eur J Med Chem. 2020 Sep 15; 202:112603.
    View in: PubMed
    Score: 0.009
  33. Donoso-Bustamante V, Borrego EA, Schiaffino-Bustamante Y, Guti?rrez DA, Millas-Vargas JP, Fuentes-Retamal S, Correa P, Carrillo I, Aguilera RJ, Miranda D, Ch?vez-B?ez I, Pulgar R, Urra FA, Varela-Ram?rez A, Araya-Maturana R. An acylhydroquinone derivative produces OXPHOS uncoupling and sensitization to BH3 mimetic ABT-199 (Venetoclax) in human promyelocytic leukemia cells. Bioorg Chem. 2020 07; 100:103935.
    View in: PubMed
    Score: 0.009
  34. Upadhyay N, Tilekar K, J?nsch N, Schweipert M, Hess JD, Henze Macias L, Mrowka P, Aguilera RJ, Choe JY, Meyer-Almes FJ, Ramaa CS. Discovery of novel N-substituted thiazolidinediones (TZDs) as HDAC8 inhibitors: in-silico studies, synthesis, and biological evaluation. Bioorg Chem. 2020 07; 100:103934.
    View in: PubMed
    Score: 0.009
  35. Philipovskiy A, Campbell A, Heydarian R, Castillo B, Dwivedi AK, McCallum R, Aguilera R, Gaur S, Nahleh Z. Adherence to Adjuvant Aromatase Inhibitor Therapy Among Postmenopausal Hispanic/Latino Women With Breast Cancer. Anticancer Res. 2020 02; 40(2):857-864.
    View in: PubMed
    Score: 0.008
  36. Iglesias-Figueroa BF, Siqueiros-Cend?n TS, Gutierrez DA, Aguilera RJ, Espinoza-S?nchez EA, Ar?valo-Gallegos S, Varela-Ramirez A, Rasc?n-Cruz Q. Recombinant human lactoferrin induces apoptosis, disruption of F-actin structure and cell cycle arrest with selective cytotoxicity on human triple negative breast cancer cells. Apoptosis. 2019 08; 24(7-8):562-577.
    View in: PubMed
    Score: 0.008
  37. Montoya A, Varela-Ramirez A, Dickerson E, Pasquier E, Torabi A, Aguilera R, Nahleh Z, Bryan B. The beta adrenergic receptor antagonist propranolol alters mitogenic and apoptotic signaling in late stage breast cancer. Biomed J. 2019 06; 42(3):155-165.
    View in: PubMed
    Score: 0.008
  38. Solis LH, Ayala Y, Portillo S, Varela-Ramirez A, Aguilera R, Boland T. Thermal inkjet bioprinting triggers the activation of the VEGF pathway in human microvascular endothelial cells in vitro. Biofabrication. 2019 07 09; 11(4):045005.
    View in: PubMed
    Score: 0.008
  39. Sharma S, Aguilera R, Rao J, Gimzewski JK. Piezoelectric needle sensor reveals mechanical heterogeneity in human thyroid tissue lesions. Sci Rep. 2019 06 26; 9(1):9282.
    View in: PubMed
    Score: 0.008
  40. Ruiz-Medina BE, Lerma D, Hwang M, Ross JA, Skouta R, Aguilera RJ, Kirken RA, Varela-Ramirez A, Robles-Escajeda E. Green barley mitigates cytotoxicity in human lymphocytes undergoing aggressive oxidative stress, via activation of both the Lyn/PI3K/Akt and MAPK/ERK pathways. Sci Rep. 2019 04 12; 9(1):6005.
    View in: PubMed
    Score: 0.008
  41. Galic Z, Alva JA, Lin A, Lyon CJ, Aguilera RJ. Characterization of a novel DNA binding domain within the amino-terminal region of the RAG-1 protein. Biochem Mol Biol Int. 1998 Jul; 45(3):535-44.
    View in: PubMed
    Score: 0.008
  42. Montoya A, Amaya CN, Belmont A, Diab N, Trevino R, Villanueva G, Rains S, Sanchez LA, Badri N, Otoukesh S, Khammanivong A, Liss D, Baca ST, Aguilera RJ, Dickerson EB, Torabi A, Dwivedi AK, Abbas A, Chambers K, Bryan BA, Nahleh Z. Use of non-selective ?-blockers is associated with decreased tumor proliferative indices in early stage breast cancer. Oncotarget. 2017 Jan 24; 8(4):6446-6460.
    View in: PubMed
    Score: 0.007
  43. Miranda GA, Chokler I, Aguilera RJ. The murine nucleolin protein is an inducible DNA and ATP binding protein which is readily detected in nuclear extracts of lipopolysaccharide-treated splenocytes. Exp Cell Res. 1995 Apr; 217(2):294-308.
    View in: PubMed
    Score: 0.006
  44. Liu M, Varela-Ramirez A, Li J, Dai L, Aguilera RJ, Zhang JY. Humoral autoimmune response to nucleophosmin in the immunodiagnosis of hepatocellular carcinoma. Oncol Rep. 2015 May; 33(5):2245-52.
    View in: PubMed
    Score: 0.006
  45. Nunes LM, Robles-Escajeda E, Santiago-Vazquez Y, Ortega NM, Lema C, Muro A, Almodovar G, Das U, Das S, Dimmock JR, Aguilera RJ, Varela-Ramirez A. The gender of cell lines matters when screening for novel anti-cancer drugs. AAPS J. 2014 Jul; 16(4):872-4.
    View in: PubMed
    Score: 0.006
  46. Santiago-Vazquez Y, Das S, Das U, Robles-Escajeda E, Ortega NM, Lema C, Varela-Ram?rez A, Aguilera RJ, Balzarini J, De Clercq E, Dimmock SG, Gorecki DK, Dimmock JR. Novel 3,5-bis(arylidene)-4-oxo-1-piperidinyl dimers: structure-activity relationships and potent antileukemic and antilymphoma cytotoxicity. Eur J Med Chem. 2014 Apr 22; 77:315-22.
    View in: PubMed
    Score: 0.006
  47. Pedroza DA, De Leon F, Varela-Ramirez A, Lema C, Aguilera RJ, Mito S. The cytotoxic effect of 2-acylated-1,4-naphthohydroquinones on leukemia/lymphoma cells. Bioorg Med Chem. 2014 Jan 15; 22(2):842-7.
    View in: PubMed
    Score: 0.005
  48. Robles-Escajeda E, Lerma D, Nyakeriga AM, Ross JA, Kirken RA, Aguilera RJ, Varela-Ramirez A. Searching in mother nature for anti-cancer activity: anti-proliferative and pro-apoptotic effect elicited by green barley on leukemia/lymphoma cells. PLoS One. 2013; 8(9):e73508.
    View in: PubMed
    Score: 0.005
  49. Oldham ED, Seelam S, Lema C, Aguilera RJ, Fiegel J, Rankin SE, Knutson BL, Lehmler HJ. Synthesis, surface properties, and biocompatibility of 1,2,3-triazole-containing alkyl ?-D-xylopyranoside surfactants. Carbohydr Res. 2013 Sep 20; 379:68-77.
    View in: PubMed
    Score: 0.005
  50. Xu W, Osei-Prempeh G, Lema C, Davis Oldham E, Aguilera RJ, Parkin S, Rankin SE, Knutson BL, Lehmler HJ. Synthesis, thermal properties, and cytotoxicity evaluation of hydrocarbon and fluorocarbon alkyl ?-D-xylopyranoside surfactants. Carbohydr Res. 2012 Feb 15; 349:12-23.
    View in: PubMed
    Score: 0.005
  51. Gonz?lez-Pantoja JF, Stern M, Jarzecki AA, Royo E, Robles-Escajeda E, Varela-Ram?rez A, Aguilera RJ, Contel M. Titanocene-phosphine derivatives as precursors to cytotoxic heterometallic TiAu2 and TiM (M = Pd, Pt) compounds. Studies of their interactions with DNA. Inorg Chem. 2011 Nov 07; 50(21):11099-110.
    View in: PubMed
    Score: 0.005
  52. Das S, Das U, Varela-Ram?rez A, Lema C, Aguilera RJ, Balzarini J, De Clercq E, Dimmock SG, Gorecki DK, Dimmock JR. Bis[3,5-bis(benzylidene)-4-oxo-1-piperidinyl]amides: a novel class of potent cytotoxins. ChemMedChem. 2011 Oct 04; 6(10):1892-9.
    View in: PubMed
    Score: 0.005
  53. Liu F, Anis R, Hwang E, Ovalle R, Varela-Ram?rez A, Aguilera RJ, Contel M. Group 11 Metal Compounds with Tripodal Bis(imidazole) Thioether Ligands. Applications as Catalysts in the Oxidation of Alkenes and as Antimicrobial Agents. Molecules. 2011 Aug 08; 16(8):6701-20.
    View in: PubMed
    Score: 0.005
  54. Nohara LL, Lema C, Bader JO, Aguilera RJ, Almeida IC. High-content imaging for automated determination of host-cell infection rate by the intracellular parasite Trypanosoma cruzi. Parasitol Int. 2010 Dec; 59(4):565-70.
    View in: PubMed
    Score: 0.004
  55. Shaik N, Mart?nez A, Augustin I, Giovinazzo H, Varela-Ram?rez A, Sana? M, Aguilera RJ, Contel M. Synthesis of apoptosis-inducing iminophosphorane organogold(III) complexes and study of their interactions with biomolecular targets. Inorg Chem. 2009 Feb 16; 48(4):1577-87.
    View in: PubMed
    Score: 0.004
  56. Cruz-Campa I, Arzola A, Santiago L, Parsons JG, Varela-Ramirez A, Aguilera RJ, Noveron JC. A novel class of metal-directed supramolecular DNA-delivery systems. Chem Commun (Camb). 2007 Jul 28; (28):2944-6.
    View in: PubMed
    Score: 0.003
  57. Rajabi L, Courreges C, Montoya J, Aguilera RJ, Primm TP. Acetophenones with selective antimycobacterial activity. Lett Appl Microbiol. 2005; 40(3):212-7.
    View in: PubMed
    Score: 0.003
  58. Solorzano-Vargas RS, Wang J, Jiang L, Tsai HV, Ontiveros LO, Vazir MA, Aguilera RJ, Mart?n MG. Multiple transcription factors in 5'-flanking region of human polymeric Ig receptor control its basal expression. Am J Physiol Gastrointest Liver Physiol. 2002 Aug; 283(2):G415-25.
    View in: PubMed
    Score: 0.002
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
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