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Connection

Co-Authors

This is a "connection" page, showing publications co-authored by Robert Kirken and Georgialina Rodriguez.
Connection Strength

3.638
  1. Rodriguez G, Martinez GS, Negrete OD, Sun S, Guo W, Xie Y, Li L, Xiao C, Ross JA, Kirken RA. JAK3 Y841 Autophosphorylation Is Critical for STAT5B Activation, Kinase Domain Stability and Dimer Formation. Int J Mol Sci. 2023 Jul 25; 24(15).
    View in: PubMed
    Score: 0.927
  2. Rodriguez G, Ross JA, Nagy ZS, Kirken RA. Forskolin-inducible cAMP pathway negatively regulates T-cell proliferation by uncoupling the interleukin-2 receptor complex. J Biol Chem. 2013 Mar 08; 288(10):7137-46.
    View in: PubMed
    Score: 0.448
  3. Rodriguez Moncivais OJ, Chavez SA, Estrada Jimenez VH, Sun S, Li L, Kirken RA, Rodriguez G. Structural Analysis of Janus Tyrosine Kinase Variants in Hematological Malignancies: Implications for Drug Development and Opportunities for Novel Therapeutic Strategies. Int J Mol Sci. 2023 Sep 26; 24(19).
    View in: PubMed
    Score: 0.235
  4. Grant AH, Rodriguez AC, Rodriguez Moncivais OJ, Sun S, Li L, Mohl JE, Leung MY, Kirken RA, Rodriguez G. JAK1 Pseudokinase V666G Mutant Dominantly Impairs JAK3 Phosphorylation and IL-2 Signaling. Int J Mol Sci. 2023 Apr 06; 24(7).
    View in: PubMed
    Score: 0.227
  5. Robles-Escajeda E, Mohl JE, Contreras L, Betancourt AP, Mancera BM, Kirken RA, Rodriguez G. Rapid Shift from SARS-CoV-2 Delta to Omicron Sub-Variants within a Dynamic Southern U.S. Borderplex. Viruses. 2023 02 28; 15(3).
    View in: PubMed
    Score: 0.225
  6. Ayala-Marin YM, Grant AH, Rodriguez G, Kirken RA. Quadruple and Truncated MEK3 Mutants Identified from Acute Lymphoblastic Leukemia Promote Degradation and Enhance Proliferation. Int J Mol Sci. 2021 Nov 11; 22(22).
    View in: PubMed
    Score: 0.206
  7. Estrada A, Rodriguez AC, Rodriguez G, Grant AH, Ayala-Marin YM, Arrieta AJ, Kirken RA. Phosphorylation of CrkL S114 induced by common gamma chain cytokines and T-cell receptor signal transduction. Sci Rep. 2021 08 20; 11(1):16951.
    View in: PubMed
    Score: 0.203
  8. Grant AH, Estrada A, Ayala-Marin YM, Alvidrez-Camacho AY, Rodriguez G, Robles-Escajeda E, Cadena-Medina DA, Rodriguez AC, Kirken RA. The Many Faces of JAKs and STATs Within the COVID-19 Storm. Front Immunol. 2021; 12:690477.
    View in: PubMed
    Score: 0.201
  9. Grant AH, Ayala-Marin YM, Mohl JE, Robles-Escajeda E, Rodriguez G, Dutil J, Kirken RA. The Genomic Landscape of a Restricted ALL Cohort from Patients Residing on the U.S./Mexico Border. Int J Environ Res Public Health. 2021 07 09; 18(14).
    View in: PubMed
    Score: 0.201
  10. Oaxaca DM, Yang-Reid SA, Ross JA, Rodriguez G, Staniswalis JG, Kirken RA. Sensitivity of imatinib-resistant T315I BCR-ABL CML to a synergistic combination of ponatinib and forskolin treatment. Tumour Biol. 2016 Sep; 37(9):12643-12654.
    View in: PubMed
    Score: 0.143
  11. Nagy ZS, Ross JA, Rodriguez G, Balint BL, Szeles L, Nagy L, Kirken RA. Genome wide mapping reveals PDE4B as an IL-2 induced STAT5 target gene in activated human PBMCs and lymphoid cancer cells. PLoS One. 2013; 8(2):e57326.
    View in: PubMed
    Score: 0.113
  12. Ross JA, Rodriguez G, Kirken RA. Analysis of Janus tyrosine kinase phosphorylation and activation. Methods Mol Biol. 2013; 967:3-20.
    View in: PubMed
    Score: 0.111
  13. Mitra A, Ross JA, Rodriguez G, Nagy ZS, Wilson HL, Kirken RA. Signal transducer and activator of transcription 5b (Stat5b) serine 193 is a novel cytokine-induced phospho-regulatory site that is constitutively activated in primary hematopoietic malignancies. J Biol Chem. 2012 May 11; 287(20):16596-608.
    View in: PubMed
    Score: 0.106
  14. Nagy ZS, Ross JA, Rodriguez G, Bader J, Dimmock J, Kirken RA. Uncoupling JAK3 activation induces apoptosis in human lymphoid cancer cells via regulating critical survival pathways. FEBS Lett. 2010 Apr 16; 584(8):1515-20.
    View in: PubMed
    Score: 0.092
  15. Sun S, Rodriguez G, Zhao G, Sanchez JE, Guo W, Du D, Rodriguez Moncivais OJ, Hu D, Liu J, Kirken RA, Li L. A novel approach to study multi-domain motions in JAK1's activation mechanism based on energy landscape. Brief Bioinform. 2024 Jan 22; 25(2).
    View in: PubMed
    Score: 0.060
  16. Sun S, Rodriguez G, Xie Y, Guo W, Hernandez AEL, Sanchez JE, Kirken RA, Li L. Phosphorylation of Tyrosine 841 Plays a Significant Role in JAK3 Activation. Life (Basel). 2023 Apr 10; 13(4).
    View in: PubMed
    Score: 0.057
  17. Valenzuela P, Oaxaca D, Di Desidero T, Parra K, Rodriguez G, Manciu M, Allegrini G, Falcone A, Bocci G, Kirken RA, Francia G. Pharmacodynamic biomarkers in metronomic chemotherapy: multiplex cytokine measurements in gastrointestinal cancer patients. Clin Exp Med. 2021 Feb; 21(1):149-159.
    View in: PubMed
    Score: 0.048
  18. Parra K, Valenzuela P, Lerma N, Gallegos A, Reza LC, Rodriguez G, Emmenegger U, Di Desidero T, Bocci G, Felder MS, Manciu M, Kirken RA, Francia G. Impact of CTLA-4 blockade in conjunction with metronomic chemotherapy on preclinical breast cancer growth. Br J Cancer. 2017 01; 116(3):324-334.
    View in: PubMed
    Score: 0.037
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
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