Seth Y. Ablordeppey to Animals
This is a "connection" page, showing publications Seth Y. Ablordeppey has written about Animals.
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0.765
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Onyameh EK, Bricker BA, Eyunni SVK, Voshavar C, Gonela UM, Ofori E, Jenkins A, Ablordeppey SY. A study of the structure-affinity relationship in SYA16263; is a D2 receptor interaction essential for inhibition of apormorphine-induced climbing behavior in mice? Bioorg Med Chem. 2021 01 15; 30:115943.
Score: 0.059
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Bricker BA, Peprah K, Kang HJ, Ablordeppey SY. Evaluation of SYA16263 as a new potential antipsychotic agent without catalepsy. Pharmacol Biochem Behav. 2019 04; 179:55-62.
Score: 0.052
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Al-Ghanim L, Zhu XY, Asong G, Ablordeppey SY. SYA 013 analogs as moderately selective sigma-2 (s2) ligands: Structure-affinity relationship studies. Bioorg Med Chem. 2019 06 15; 27(12):2421-2426.
Score: 0.052
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Etukala JR, Zhu XY, Eyunni SV, Onyameh EK, Ofori E, Bricker BA, Kang HJ, Huang XP, Roth BL, Ablordeppey SY. Development of CNS multi-receptor ligands: Modification of known D2 pharmacophores. Bioorg Med Chem. 2016 08 15; 24(16):3671-9.
Score: 0.043
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Sampson D, Bricker B, Zhu XY, Peprah K, Lamango NS, Setola V, Roth BL, Ablordeppey SY. Further evaluation of the tropane analogs of haloperidol. Bioorg Med Chem Lett. 2014 Sep 01; 24(17):4294-7.
Score: 0.038
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Sampson D, Zhu XY, Eyunni SV, Etukala JR, Ofori E, Bricker B, Lamango NS, Setola V, Roth BL, Ablordeppey SY. Identification of a new selective dopamine D4 receptor ligand. Bioorg Med Chem. 2014 Jun 15; 22(12):3105-14.
Score: 0.037
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Bricker B, Sampson D, Ablordeppey SY. Evaluation of the potential of antipsychotic agents to induce catalepsy in rats: assessment of a new, commercially available, semi-automated instrument. Pharmacol Biochem Behav. 2014 May; 120:109-16.
Score: 0.037
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Bolden S, Zhu XY, Etukala JR, Boateng C, Mazu T, Flores-Rozas H, Jacob MR, Khan SI, Walker LA, Ablordeppey SY. Structure-activity relationship (SAR) and preliminary mode of action studies of 3-substituted benzylthioquinolinium iodide as anti-opportunistic infection agents. Eur J Med Chem. 2013; 70:130-42.
Score: 0.036
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Bolden S, Boateng CA, Zhu XY, Etukala JR, Eyunni SK, Jacob MR, Khan SI, Ablordeppey SY. CoMFA studies and in vitro evaluation of some 3-substituted benzylthio quinolinium salts as anticryptococcal agents. Bioorg Med Chem. 2013 Nov 15; 21(22):7194-201.
Score: 0.035
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Sikazwe D, Grillo A, Ramsinghani S, Davis J, McQuiston K, Ablordeppey SY. Small diverse antioxidant functionalities for oxidative stress disease drug discovery. Mini Rev Med Chem. 2012 Jul; 12(8):768-74.
Score: 0.033
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Bricker B, Jackson T, Boateng B, Zhu XY, Ablordeppey SY. Evaluation of the behavioral and pharmacokinetic profile of SYA013, a homopiperazine analog of haloperidol in rats. Pharmacol Biochem Behav. 2012 Aug; 102(2):294-301.
Score: 0.032
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Mazu TK, Etukala JR, Jacob MR, Khan SI, Walker LA, Ablordeppey SY. d-Carbolines and their ring-opened analogs: synthesis and evaluation against fungal and bacterial opportunistic pathogens. Eur J Med Chem. 2011 Jun; 46(6):2378-85.
Score: 0.030
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Boateng CA, Zhu XY, Jacob MR, Khan SI, Walker LA, Ablordeppey SY. Optimization of 3-(phenylthio)quinolinium compounds against opportunistic fungal pathogens. Eur J Med Chem. 2011 May; 46(5):1789-97.
Score: 0.030
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Boateng CA, Eyunni SV, Zhu XY, Etukala JR, Bricker BA, Ashfaq MK, Jacob MR, Khan SI, Walker LA, Ablordeppey SY. Benzothieno[3,2-b]quinolinium and 3-(phenylthio)quinolinium compounds: Synthesis and evaluation against opportunistic fungal pathogens. Bioorg Med Chem. 2011 Jan 01; 19(1):458-70.
Score: 0.029
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Ablordeppey SY, Altundas R, Bricker B, Zhu XY, Kumar EV, Jackson T, Khan A, Roth BL. Identification of a butyrophenone analog as a potential atypical antipsychotic agent: 4-[4-(4-chlorophenyl)-1,4-diazepan-1-yl]-1-(4-fluorophenyl)butan-1-one. Bioorg Med Chem. 2008 Aug 01; 16(15):7291-301.
Score: 0.025
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Kumar EV, Etukala JR, Ablordeppey SY. Indolo[3,2-b]quinolines: synthesis, biological evaluation and structure activity-relationships. Mini Rev Med Chem. 2008 Jun; 8(6):538-54.
Score: 0.025
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Zhu XY, Mardenborough LG, Li S, Khan A, Zhang W, Fan P, Jacob M, Khan S, Walker L, Ablordeppey SY. Synthesis and evaluation of isosteres of N-methyl indolo[3,2-b]-quinoline (cryptolepine) as new antiinfective agents. Bioorg Med Chem. 2007 Jan 15; 15(2):686-95.
Score: 0.022
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Ablordeppey SY, Lyles-Eggleston M, Bricker B, Zhang W, Zhu X, Goodman C, Roth BL. Evaluation of the eutomer of 4-{3-(4-chlorophenyl)-3-hydroxypyrrolidin-1-yl}-1-(4-fluorophenyl)butan-1-one, {(+)-SYA 09}, a pyrrolidine analog of haloperidol. Bioorg Med Chem Lett. 2006 Jun 15; 16(12):3219-23.
Score: 0.021
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Mardenborough LG, Zhu XY, Fan P, Jacob MR, Khan SI, Walker LA, Ablordeppey SY. Identification of bis-quindolines as new antiinfective agents. Bioorg Med Chem. 2005 Jun 02; 13(12):3955-63.
Score: 0.020
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Lyles-Eggleston M, Altundas R, Xia J, Sikazwe DM, Fan P, Yang Q, Li S, Zhang W, Zhu X, Schmidt AW, Vanase-Frawley M, Shrihkande A, Villalobos A, Borne RF, Ablordeppey SY. Design, synthesis, and evaluation of metabolism-based analogues of haloperidol incapable of forming MPP+-like species. J Med Chem. 2004 Jan 29; 47(3):497-508.
Score: 0.018
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Sikazwe DM, Li S, Lyles-Eggleston M, Ablordeppey SY. The acute EPS of haloperidol may be unrelated to its metabolic transformation to BCPP+. Bioorg Med Chem Lett. 2003 Nov 03; 13(21):3779-82.
Score: 0.018
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Ablordeppey SY, Fischer JB, Law H, Glennon RA. Probing the proposed phenyl-A region of the sigma-1 receptor. Bioorg Med Chem. 2002 Aug; 10(8):2759-65.
Score: 0.016
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Ablordeppey SY, Fischer JB, Glennon RA. Is a nitrogen atom an important pharmacophoric element in sigma ligand binding? Bioorg Med Chem. 2000 Aug; 8(8):2105-11.
Score: 0.014
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Ablordeppey SY, Borne RF. Detection of a neurotoxic quaternary pyridinium metabolite in the liver of haloperidol-treated rats. Pharmacol Biochem Behav. 1993 Nov; 46(3):739-44.
Score: 0.009
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Oyekan AO, Ablordeppey SY. Effects of cryptolepine on collagen-induced aggregation and on the mobilization and metabolism of arachidonic acid by rabbit platelets. Gen Pharmacol. 1993 Sep; 24(5):1285-90.
Score: 0.009
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Oyekan AO, Ablordeppey SY. The mechanism(s) of the antiaggregatory effects of cryptolepine: the role of cyclic adenosine monophosphate and cellular Ca2+. Gen Pharmacol. 1993 Mar; 24(2):461-9.
Score: 0.009
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Duverna R, Ablordeppey SY, Lamango NS. Biochemical and docking analysis of substrate interactions with polyisoprenylated methylated protein methyl esterase. Curr Cancer Drug Targets. 2010 Sep; 10(6):634-48.
Score: 0.007
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Billups J, Jones C, Jackson TL, Ablordeppey SY, Spencer SD. Simultaneous RP-HPLC-DAD quantification of bromocriptine, haloperidol and its diazepane structural analog in rat plasma with droperidol as internal standard for application to drug-interaction pharmacokinetics. Biomed Chromatogr. 2010 Jul; 24(7):699-705.
Score: 0.007
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Glennon RA, Ablordeppey SY, Ismaiel AM, el-Ashmawy MB, Fischer JB, Howie KB. Structural features important for sigma 1 receptor binding. J Med Chem. 1994 Apr 15; 37(8):1214-9.
Score: 0.002
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Salako Q, Ablordeppey SY, Dwuma-Badu D, Thornback JR. Radioiodination and preliminary in vivo investigation of the alkaloid cryptolepine. Int J Appl Radiat Isot. 1985 Dec; 36(12):1003-4.
Score: 0.001