Khosrow Kashfi to Humans
This is a "connection" page, showing publications Khosrow Kashfi has written about Humans.
Connection Strength
1.608
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O'Connor JL, Fountos DM, Firouzan B, Azizi F, Ghasemi R, Kashfi K. The role of gasotransmitters in Parkinson's disease: Interplay of nitric oxide, carbon monoxide, and hydrogen sulfide. Neurotherapeutics. 2025 Oct; 22(6):e00710.
Score: 0.043
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Kolawole OR, Kashfi K. Reprogramming inflammation: Mechanisms and therapeutic targeting of eicosanoids and pro-resolving mediators. Eur J Pharmacol. 2025 Sep 15; 1003:177924.
Score: 0.043
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Ghasemi A, Jeddi S, Kashfi K. Brain glucose metabolism: Role of nitric oxide. Biochem Pharmacol. 2025 02; 232:116728.
Score: 0.041
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Chattopadhyay M, Nath N, Kodela R, Metkar S, Soyemi SA, Kashfi K. NOSH-aspirin (NBS-1120) inhibits estrogen receptor-negative breast cancer in?vitro and in?vivo by modulating redox-sensitive signaling pathways. J Pharmacol Exp Ther. 2025 Jan; 392(1):100019.
Score: 0.041
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Dos Reis RA, Sarkar I, Rodrigues MG, Matson JB, Seabra AB, Kashfi K. NO- and H2S- releasing nanomaterials: A crosstalk signaling pathway in cancer. Nitric Oxide. 2024 Oct 01; 151:17-30.
Score: 0.040
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Oza PP, Kashfi K. The Triple Crown: NO, CO, and H2S in cancer cell biology. Pharmacol Ther. 2023 09; 249:108502.
Score: 0.037
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Oza PP, Kashfi K. The evolving landscape of PCSK9 inhibition in cancer. Eur J Pharmacol. 2023 Jun 15; 949:175721.
Score: 0.036
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Alimardan Z, Abbasi M, Hasanzadeh F, Aghaei M, Khodarahmi G, Kashfi K. Heat shock proteins and cancer: The FoxM1 connection. Biochem Pharmacol. 2023 05; 211:115505.
Score: 0.036
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Kashfi K. Dedication to Dr. Larry K. Keefer at the Sixth International Workshop on Nitric Oxide in Cancer and Beyond. Crit Rev Oncog. 2023; 28(1):xi-xviii.
Score: 0.036
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Kashfi K. Fifty Years of Diazeniumdiolate Research: A Tribute to Dr. Larry K. Keefer. Crit Rev Oncog. 2023; 28(1):47-55.
Score: 0.036
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Ranjbar T, Oza PP, Kashfi K. The Renin-Angiotensin-Aldosterone System, Nitric Oxide, and Hydrogen Sulfide at the Crossroads of Hypertension and COVID-19: Racial Disparities and Outcomes. Int J Mol Sci. 2022 Nov 11; 23(22).
Score: 0.035
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Kashfi K, Patel KK. Carbon monoxide and its role in human physiology: A brief historical perspective. Biochem Pharmacol. 2022 10; 204:115230.
Score: 0.035
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Oza PP, Kashfi K. Utility of NO and H2S donating platforms in managing COVID-19: Rationale and promise. Nitric Oxide. 2022 11 01; 128:72-102.
Score: 0.035
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Patel KK, Sehgal VS, Kashfi K. Molecular targets of statins and their potential side effects: Not all the glitter is gold. Eur J Pharmacol. 2022 May 05; 922:174906.
Score: 0.034
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Kolawole OR, Kashfi K. NSAIDs and Cancer Resolution: New Paradigms beyond Cyclooxygenase. Int J Mol Sci. 2022 Jan 27; 23(3).
Score: 0.034
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Kashfi K, Kannikal J, Nath N. Macrophage Reprogramming and Cancer Therapeutics: Role of iNOS-Derived NO. Cells. 2021 11 16; 10(11).
Score: 0.033
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Patel KK, Kashfi K. Lipoproteins and cancer: The role of HDL-C, LDL-C, and cholesterol-lowering drugs. Biochem Pharmacol. 2022 02; 196:114654.
Score: 0.032
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Panigrahy D, Gilligan MM, Serhan CN, Kashfi K. Resolution of inflammation: An organizing principle in biology and medicine. Pharmacol Ther. 2021 11; 227:107879.
Score: 0.032
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Kashfi K. Nitric oxide in cancer and beyond. Biochem Pharmacol. 2020 06; 176:114006.
Score: 0.030
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Dillon KM, Carrazzone RJ, Matson JB, Kashfi K. The evolving landscape for cellular nitric oxide and hydrogen sulfide delivery systems: A new era of customized medications. Biochem Pharmacol. 2020 06; 176:113931.
Score: 0.029
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Nath N, Kashfi K. Tumor associated macrophages and 'NO'. Biochem Pharmacol. 2020 06; 176:113899.
Score: 0.029
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Gheibi S, Samsonov AP, Gheibi S, Vazquez AB, Kashfi K. Regulation of carbohydrate metabolism by nitric oxide and hydrogen sulfide: Implications in diabetes. Biochem Pharmacol. 2020 06; 176:113819.
Score: 0.029
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Bahadoran Z, Mirmiran P, Ghasemi A, Kashfi K. Type 2 Diabetes and Cancer: The Nitric Oxide Connection. Crit Rev Oncog. 2019; 24(3):235-242.
Score: 0.027
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Kashfi K, Rosen CL, Aslan M. Obesity, Type-2 Diabetes and Cancer: Mechanistic Insights. Crit Rev Oncog. 2019; 24(3):285-305.
Score: 0.027
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Kashfi K. The role of hydrogen sulfide in health and disease. Biochem Pharmacol. 2018 03; 149:1-4.
Score: 0.026
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Kashfi K. The dichotomous role of H2S in cancer cell biology? D?j? vu all over again. Biochem Pharmacol. 2018 03; 149:205-223.
Score: 0.025
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Kashfi K. Utility Of Nitric Oxide And Hydrogen Sulfide-Releasing Chimeras As Anticancer Agents. Redox Biol. 2015 08; 5:420.
Score: 0.022
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Vannini F, Kodela R, Chattopadhyay M, Kashfi K. NOSH-Aspirin Inhibits Colon Cancer Cell Growth: Effects Of Positional Isomerism. Redox Biol. 2015 08; 5:421.
Score: 0.022
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Kodela R, Chattopadhyay M, Vel?zquez-Mart?nez CA, Kashfi K. NOSH-aspirin (NBS-1120), a novel nitric oxide- and hydrogen sulfide-releasing hybrid has enhanced chemo-preventive properties compared to aspirin, is gastrointestinal safe with all the classic therapeutic indications. Biochem Pharmacol. 2015 Dec 15; 98(4):564-72.
Score: 0.022
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Kodela R, Nath N, Chattopadhyay M, Nesbitt DE, Vel?zquez-Mart?nez CA, Kashfi K. Hydrogen sulfide-releasing naproxen suppresses colon cancer cell growth and inhibits NF-?B signaling. Drug Des Devel Ther. 2015; 9:4873-82.
Score: 0.021
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Vannini F, Chattopadhyay M, Kodela R, Rao PPN, Kashfi K. Positional isomerism markedly affects the growth inhibition of colon cancer cells by NOSH-aspirin: COX inhibition and modeling. Redox Biol. 2015 Dec; 6:318-325.
Score: 0.021
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Vannini F, MacKessack-Leitch AC, Eschbach EK, Chattopadhyay M, Kodela R, Kashfi K. Synthesis and anti-cancer potential of the positional isomers of NOSH-aspirin (NBS-1120) a dual nitric oxide and hydrogen sulfide releasing hybrid. Bioorg Med Chem Lett. 2015 Oct 15; 25(20):4677-82.
Score: 0.021
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Nath N, Chattopadhyay M, Rodes DB, Nazarenko A, Kodela R, Kashfi K. Nitric Oxide-Releasing Aspirin Suppresses NF-?B Signaling in Estrogen Receptor Negative Breast Cancer Cells in Vitro and in Vivo. Molecules. 2015 Jul 09; 20(7):12481-99.
Score: 0.021
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Chattopadhyay M, Nath N, Kodela R, Sobocki T, Metkar S, Gan ZY, Kashfi K. Hydrogen sulfide-releasing aspirin inhibits the growth of leukemic Jurkat cells and modulates ?-catenin expression. Leuk Res. 2013 Oct; 37(10):1302-8.
Score: 0.019
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Kashfi K. Anti-cancer activity of new designer hydrogen sulfide-donating hybrids. Antioxid Redox Signal. 2014 Feb 10; 20(5):831-46.
Score: 0.018
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Nath N, Liu X, Jacobs L, Kashfi K. Flurbiprofen benzyl nitrate (NBS-242) inhibits the growth of A-431 human epidermoid carcinoma cells and targets ?-catenin. Drug Des Devel Ther. 2013; 7:389-96.
Score: 0.018
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Kodela R, Chattopadhyay M, Goswami S, Gan ZY, Rao PP, Nia KV, Vel?zquez-Mart?nez CA, Kashfi K. Positional isomers of aspirin are equally potent in inhibiting colon cancer cell growth: differences in mode of cyclooxygenase inhibition. J Pharmacol Exp Ther. 2013 Apr; 345(1):85-94.
Score: 0.018
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Kashfi K. Dysfunctional cell signaling dynamics in oncology: diagnostic, prognostic and treatment opportunities. Biochem Pharmacol. 2013 Mar 01; 85(5):595-596.
Score: 0.018
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Kashfi K, Olson KR. Biology and therapeutic potential of hydrogen sulfide and hydrogen sulfide-releasing chimeras. Biochem Pharmacol. 2013 Mar 01; 85(5):689-703.
Score: 0.018
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Chattopadhyay M, Kodela R, Olson KR, Kashfi K. NOSH-aspirin (NBS-1120), a novel nitric oxide- and hydrogen sulfide-releasing hybrid is a potent inhibitor of colon cancer cell growth in vitro and in a xenograft mouse model. Biochem Biophys Res Commun. 2012 Mar 16; 419(3):523-8.
Score: 0.017
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Chattopadhyay M, Kodela R, Nath N, Dastagirzada YM, Vel?zquez-Mart?nez CA, Boring D, Kashfi K. Hydrogen sulfide-releasing NSAIDs inhibit the growth of human cancer cells: a general property and evidence of a tissue type-independent effect. Biochem Pharmacol. 2012 Mar 15; 83(6):715-22.
Score: 0.017
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Chattopadhyay M, Kodela R, Nath N, Street CR, Vel?zquez-Mart?nez CA, Boring D, Kashfi K. Hydrogen sulfide-releasing aspirin modulates xenobiotic metabolizing enzymes in vitro and in vivo. Biochem Pharmacol. 2012 Mar 15; 83(6):733-40.
Score: 0.017
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Chattopadhyay M, Kodela R, Nath N, Barsegian A, Boring D, Kashfi K. Hydrogen sulfide-releasing aspirin suppresses NF-?B signaling in estrogen receptor negative breast cancer cells in vitro and in vivo. Biochem Pharmacol. 2012 Mar 15; 83(6):723-32.
Score: 0.017
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Kodela R, Chattopadhyay M, Nath N, Cieciura LZ, Pospishill L, Boring D, Crowell JA, Kashfi K. Synthesis and biological activity of acetyl-protected hydroxybenzyl diethyl phosphates (EHBP) as potential chemotherapeutic agents. Bioorg Med Chem Lett. 2011 Dec 01; 21(23):7146-50.
Score: 0.016
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Nath N, Chattopadhyay M, Pospishil L, Cieciura LZ, Goswami S, Kodela R, Saavedra JE, Keefer LK, Kashfi K. JS-K, a nitric oxide-releasing prodrug, modulates ?-catenin/TCF signaling in leukemic Jurkat cells: evidence of an S-nitrosylated mechanism. Biochem Pharmacol. 2010 Dec 01; 80(11):1641-9.
Score: 0.015
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Chattopadhyay M, Goswami S, Rodes DB, Kodela R, Velazquez CA, Boring D, Crowell JA, Kashfi K. NO-releasing NSAIDs suppress NF-?B signaling in vitro and in vivo through S-nitrosylation. Cancer Lett. 2010 Dec 08; 298(2):204-11.
Score: 0.015
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Nath N, Chattopadhyay M, Kodela R, Tian S, Vlismas P, Boring D, Crowell JA, Kashfi K. Modulation of stress genes expression profile by nitric oxide-releasing aspirin in Jurkat T leukemia cells. Biochem Pharmacol. 2010 Jun 15; 79(12):1759-71.
Score: 0.015
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Kashfi K. Anti-inflammatory agents as cancer therapeutics. Adv Pharmacol. 2009; 57:31-89.
Score: 0.014
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Nath N, Vassell R, Chattopadhyay M, Kogan M, Kashfi K. Nitro-aspirin inhibits MCF-7 breast cancer cell growth: effects on COX-2 expression and Wnt/beta-catenin/TCF-4 signaling. Biochem Pharmacol. 2009 Nov 15; 78(10):1298-304.
Score: 0.014
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Kashfi K, Rigas B. The mechanism of action of nitric oxide-donating aspirin. Biochem Biophys Res Commun. 2007 Jul 13; 358(4):1096-101.
Score: 0.012
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Kashfi K, Rigas B. Non-COX-2 targets and cancer: expanding the molecular target repertoire of chemoprevention. Biochem Pharmacol. 2005 Oct 01; 70(7):969-86.
Score: 0.011
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Kashfi K, Rigas B. Molecular targets of nitric-oxide-donating aspirin in cancer. Biochem Soc Trans. 2005 Aug; 33(Pt 4):701-4.
Score: 0.011
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Jeddi S, Kashfi K, Ghasemi A. The potential role of nitrate, a nitric oxide donor, in the prevention and treatment of diabetic osteoporosis. Front Endocrinol (Lausanne). 2025; 16:1480838.
Score: 0.011
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Farahani A, Farahani A, Kashfi K, Ghasemi A. Inducible nitric oxide synthase (iNOS): More than an inducible enzyme? Rethinking the classification of NOS isoforms. Pharmacol Res. 2025 Jun; 216:107781.
Score: 0.011
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Mousavi M, Moridi Farimani M, Kashfi K, Ghasemi A. Antidiabetic Potential of Sophora Species: Mechanisms, Bioactive Constituents, and Therapeutic Prospects. Planta Med. 2025 Sep; 91(10-11):546-557.
Score: 0.010
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Farahani A, Farahani A, Kashfi K, Ghasemi A. Inhibition of hepatic gluconeogenesis in type 2 diabetes by metformin: complementary role of nitric oxide. Med Gas Res. 2025 Dec 01; 15(4):507-519.
Score: 0.010
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Rigas B, Kashfi K. Cancer prevention: a new era beyond cyclooxygenase-2. J Pharmacol Exp Ther. 2005 Jul; 314(1):1-8.
Score: 0.010
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Nath N, Labaze G, Rigas B, Kashfi K. NO-donating aspirin inhibits the growth of leukemic Jurkat cells and modulates beta-catenin expression. Biochem Biophys Res Commun. 2005 Jan 07; 326(1):93-9.
Score: 0.010
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Bahadoran Z, Mirmiran P, Kashfi K, Ghasemi A. Effects of time-restricted feeding (TRF)-model of intermittent fasting on adipose organ: a narrative review. Eat Weight Disord. 2024 Dec 24; 29(1):77.
Score: 0.010
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Kashfi K, Borgo S, Williams JL, Chen J, Gao J, Glekas A, Benedini F, Del Soldato P, Rigas B. Positional isomerism markedly affects the growth inhibition of colon cancer cells by nitric oxide-donating aspirin in vitro and in vivo. J Pharmacol Exp Ther. 2005 Mar; 312(3):978-88.
Score: 0.010
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Bahadoran Z, Mirmiran P, Hosseinpanah F, Kashfi K, Ghasemi A. Nitric oxide-based treatments improve wound healing associated with diabetes mellitus. Med Gas Res. 2025 Mar 01; 15(1):23-35.
Score: 0.010
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Rigas B, Kashfi K. Nitric-oxide-donating NSAIDs as agents for cancer prevention. Trends Mol Med. 2004 Jul; 10(7):324-30.
Score: 0.010
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Ghasemi A, Jeddi S, Yousefzadeh N, Kashfi K, Norouzirad R. Dissolving sodium hydrosulfide in drinking water is not a good source of hydrogen sulfide for animal studies. Sci Rep. 2023 12 09; 13(1):21839.
Score: 0.010
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Bahadoran Z, Mirmiran P, Kashfi K, Ghasemi A. Vascular nitric oxide resistance in type 2 diabetes. Cell Death Dis. 2023 07 11; 14(7):410.
Score: 0.009
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Aghaz F, Asadi Z, Sajadimajd S, Kashfi K, Arkan E, Rahimi Z. Codelivery of resveratrol melatonin utilizing pH responsive sericin based nanocarriers inhibits the proliferation of breast cancer cell line at the different pH. Sci Rep. 2023 07 08; 13(1):11090.
Score: 0.009
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Yousefzadeh N, Jeddi S, Zarkesh M, Norouzirad R, Kashfi K, Ghasemi A. Protective effects of long-term nitrate administration against ovariectomy-induced kidney dysfunction in rats. Pharmacol Rep. 2023 Aug; 75(4):979-994.
Score: 0.009
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Abbasi M, Mahboubi-Rabbani M, Kashfi K, Sadeghi-Aliabadi H. Prediction of dual NF-?B/I?B inhibitors using an integrative in-silico approaches. J Biomol Struct Dyn. 2023; 41(23):14164-14178.
Score: 0.009
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Bagheripour F, Jeddi S, Kashfi K, Ghasemi A. Metabolic effects of L-citrulline in type 2 diabetes. Acta Physiol (Oxf). 2023 03; 237(3):e13937.
Score: 0.009
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Kashfi K, Rayyan Y, Qiao LL, Williams JL, Chen J, Del Soldato P, Traganos F, Rigas B, Ryann Y. Nitric oxide-donating nonsteroidal anti-inflammatory drugs inhibit the growth of various cultured human cancer cells: evidence of a tissue type-independent effect. J Pharmacol Exp Ther. 2002 12; 303(3):1273-82.
Score: 0.009
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Bahadoran Z, Mirmiran P, Kashfi K, Ghasemi A. Carbon monoxide and ?-cell function: Implications for type 2 diabetes mellitus. Biochem Pharmacol. 2022 07; 201:115048.
Score: 0.009
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Bahadoran Z, Jeddi S, Mirmiran P, Kashfi K, Azizi F, Ghasemi A. Association between serum hydrogen sulfide concentrations and dysglycemia: a population-based study. BMC Endocr Disord. 2022 Mar 28; 22(1):79.
Score: 0.008
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Jeddi S, Yousefzadeh N, Kashfi K, Ghasemi A. Role of nitric oxide in type 1 diabetes-induced osteoporosis. Biochem Pharmacol. 2022 03; 197:114888.
Score: 0.008
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Baidoo JNE, Mukherjee S, Kashfi K, Banerjee P. A New Perspective on Cancer Therapy: Changing the Treaded Path? Int J Mol Sci. 2021 Sep 11; 22(18).
Score: 0.008
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Bahadoran Z, Mirmiran P, Kashfi K, Ghasemi A. Hyperuricemia-induced endothelial insulin resistance: the nitric oxide connection. Pflugers Arch. 2022 01; 474(1):83-98.
Score: 0.008
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Kaur K, Enders P, Zhu Y, Bratton AF, Powell CR, Kashfi K, Matson JB. Amino acid-based H2S donors: N-thiocarboxyanhydrides that release H2S with innocuous byproducts. Chem Commun (Camb). 2021 Jun 03; 57(45):5522-5525.
Score: 0.008
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Bahadoran Z, Mirmiran P, Kashfi K, Ghasemi A. Lost-in-Translation of Metabolic Effects of Inorganic Nitrate in Type 2 Diabetes: Is Ascorbic Acid the Answer? Int J Mol Sci. 2021 Apr 29; 22(9).
Score: 0.008
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Tabatabaei Dakhili SA, P?rez DJ, Gopal K, Haque M, Ussher JR, Kashfi K, Vel?zquez-Mart?nez CA. SP1-independent inhibition of FOXM1 by modified thiazolidinediones. Eur J Med Chem. 2021 Jan 01; 209:112902.
Score: 0.008
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Bahadoran Z, Mirmiran P, Kashfi K, Ghasemi A. Importance of Systematic Reviews and Meta-analyses of Animal Studies: Challenges for Animal-to-Human Translation. J Am Assoc Lab Anim Sci. 2020 09 01; 59(5):469-477.
Score: 0.008
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Gheibi S, Jeddi S, Kashfi K, Ghasemi A. Regulation of vascular tone homeostasis by NO and H2S: Implications in hypertension. Biochem Pharmacol. 2018 03; 149:42-59.
Score: 0.006
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Vannini F, Kashfi K, Nath N. The dual role of iNOS in cancer. Redox Biol. 2015 Dec; 6:334-343.
Score: 0.005
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Lee M, McGeer E, Kodela R, Kashfi K, McGeer PL. NOSH-aspirin (NBS-1120), a novel nitric oxide and hydrogen sulfide releasing hybrid, attenuates neuroinflammation induced by microglial and astrocytic activation: a new candidate for treatment of neurodegenerative disorders. Glia. 2013 Oct; 61(10):1724-34.
Score: 0.005
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Jain S, Tran S, El Gendy MA, Kashfi K, Jurasz P, Vel?zquez-Mart?nez CA. Nitric oxide release is not required to decrease the ulcerogenic profile of nonsteroidal anti-inflammatory drugs. J Med Chem. 2012 Jan 26; 55(2):688-96.
Score: 0.004
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Gao J, Kashfi K, Liu X, Rigas B. NO-donating aspirin induces phase II enzymes in vitro and in vivo. Carcinogenesis. 2006 Apr; 27(4):803-10.
Score: 0.003
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Spiegel A, Hundley TR, Chen J, Gao J, Ouyang N, Liu X, Go MF, Tsioulias GJ, Kashfi K, Rigas B. NO-donating aspirin inhibits both the expression and catalytic activity of inducible nitric oxide synthase in HT-29 human colon cancer cells. Biochem Pharmacol. 2005 Oct 01; 70(7):993-1000.
Score: 0.003
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Gao J, Kashfi K, Rigas B. In vitro metabolism of nitric oxide-donating aspirin: the effect of positional isomerism. J Pharmacol Exp Ther. 2005 Mar; 312(3):989-97.
Score: 0.003
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Yeh RK, Chen J, Williams JL, Baluch M, Hundley TR, Rosenbaum RE, Kalala S, Traganos F, Benardini F, del Soldato P, Kashfi K, Rigas B. NO-donating nonsteroidal antiinflammatory drugs (NSAIDs) inhibit colon cancer cell growth more potently than traditional NSAIDs: a general pharmacological property? Biochem Pharmacol. 2004 Jun 15; 67(12):2197-205.
Score: 0.002
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Williams JL, Nath N, Chen J, Hundley TR, Gao J, Kopelovich L, Kashfi K, Rigas B. Growth inhibition of human colon cancer cells by nitric oxide (NO)-donating aspirin is associated with cyclooxygenase-2 induction and beta-catenin/T-cell factor signaling, nuclear factor-kappaB, and NO synthase 2 inhibition: implications for chemoprevention. Cancer Res. 2003 Nov 15; 63(22):7613-8.
Score: 0.002
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Nath N, Kashfi K, Chen J, Rigas B. Nitric oxide-donating aspirin inhibits beta-catenin/T cell factor (TCF) signaling in SW480 colon cancer cells by disrupting the nuclear beta-catenin-TCF association. Proc Natl Acad Sci U S A. 2003 Oct 28; 100(22):12584-9.
Score: 0.002
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Kaza CS, Kashfi K, Rigas B. Colon cancer prevention with NO-releasing NSAIDs. Prostaglandins Other Lipid Mediat. 2002 Feb; 67(2):107-20.
Score: 0.002