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Khosrow Kashfi to Animals

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This is a "connection" page, showing publications Khosrow Kashfi has written about Animals.
Khosrow Kashfi
Connection Strength
1.893
Animals
  1. O'Connor JL, Fountos DM, Firouzan B, Azizi F, Ghasemi R, Kashfi K. The role of gasotransmitters in Parkinson's disease: Interplay of nitric oxide, carbon monoxide, and hydrogen sulfide. Neurotherapeutics. 2025 Oct; 22(6):e00710.
    View in: PubMed
    Score: 0.071
  2. Kolawole OR, Kashfi K. Reprogramming inflammation: Mechanisms and therapeutic targeting of eicosanoids and pro-resolving mediators. Eur J Pharmacol. 2025 Sep 15; 1003:177924.
    View in: PubMed
    Score: 0.070
  3. Firouzan B, Ghasemi R, Tetteh MT, Matson JB, Kashfi K. NOSH-aspirin (NBS-1120) attenuates motor defects and dopaminergic neuron degeneration in a rat model of Parkinson's disease. Eur J Pharmacol. 2025 Sep 05; 1002:177733.
    View in: PubMed
    Score: 0.070
  4. Ghasemi A, Jeddi S, Kashfi K. Brain glucose metabolism: Role of nitric oxide. Biochem Pharmacol. 2025 02; 232:116728.
    View in: PubMed
    Score: 0.068
  5. Chattopadhyay M, Nath N, Kodela R, Metkar S, Soyemi SA, Kashfi K. NOSH-aspirin (NBS-1120) inhibits estrogen receptor-negative breast cancer in?vitro and in?vivo by modulating redox-sensitive signaling pathways. J Pharmacol Exp Ther. 2025 Jan; 392(1):100019.
    View in: PubMed
    Score: 0.067
  6. Dos Reis RA, Sarkar I, Rodrigues MG, Matson JB, Seabra AB, Kashfi K. NO- and H2S- releasing nanomaterials: A crosstalk signaling pathway in cancer. Nitric Oxide. 2024 Oct 01; 151:17-30.
    View in: PubMed
    Score: 0.066
  7. Kashfi K, Kannikal J, Nath N. Macrophage Reprogramming and Cancer Therapeutics: Role of iNOS-Derived NO. Cells. 2021 11 16; 10(11).
    View in: PubMed
    Score: 0.055
  8. Patel KK, Kashfi K. Lipoproteins and cancer: The role of HDL-C, LDL-C, and cholesterol-lowering drugs. Biochem Pharmacol. 2022 02; 196:114654.
    View in: PubMed
    Score: 0.053
  9. Dillon KM, Carrazzone RJ, Matson JB, Kashfi K. The evolving landscape for cellular nitric oxide and hydrogen sulfide delivery systems: A new era of customized medications. Biochem Pharmacol. 2020 06; 176:113931.
    View in: PubMed
    Score: 0.049
  10. Nath N, Kashfi K. Tumor associated macrophages and 'NO'. Biochem Pharmacol. 2020 06; 176:113899.
    View in: PubMed
    Score: 0.049
  11. Chattopadhyay M, Kodela R, Santiago G, Le TTC, Nath N, Kashfi K. NOSH-aspirin (NBS-1120) inhibits pancreatic cancer cell growth in a xenograft mouse model: Modulation of FoxM1, p53, NF-?B, iNOS, caspase-3 and ROS. Biochem Pharmacol. 2020 06; 176:113857.
    View in: PubMed
    Score: 0.048
  12. Gheibi S, Samsonov AP, Gheibi S, Vazquez AB, Kashfi K. Regulation of carbohydrate metabolism by nitric oxide and hydrogen sulfide: Implications in diabetes. Biochem Pharmacol. 2020 06; 176:113819.
    View in: PubMed
    Score: 0.048
  13. Bahadoran Z, Mirmiran P, Ghasemi A, Kashfi K. Type 2 Diabetes and Cancer: The Nitric Oxide Connection. Crit Rev Oncog. 2019; 24(3):235-242.
    View in: PubMed
    Score: 0.045
  14. Kashfi K. The dichotomous role of H2S in cancer cell biology? D?j? vu all over again. Biochem Pharmacol. 2018 03; 149:205-223.
    View in: PubMed
    Score: 0.042
  15. Kashfi K. Utility Of Nitric Oxide And Hydrogen Sulfide-Releasing Chimeras As Anticancer Agents. Redox Biol. 2015 08; 5:420.
    View in: PubMed
    Score: 0.036
  16. Kodela R, Chattopadhyay M, Vel?zquez-Mart?nez CA, Kashfi K. NOSH-aspirin (NBS-1120), a novel nitric oxide- and hydrogen sulfide-releasing hybrid has enhanced chemo-preventive properties compared to aspirin, is gastrointestinal safe with all the classic therapeutic indications. Biochem Pharmacol. 2015 Dec 15; 98(4):564-72.
    View in: PubMed
    Score: 0.036
  17. Kodela R, Nath N, Chattopadhyay M, Nesbitt DE, Vel?zquez-Mart?nez CA, Kashfi K. Hydrogen sulfide-releasing naproxen suppresses colon cancer cell growth and inhibits NF-?B signaling. Drug Des Devel Ther. 2015; 9:4873-82.
    View in: PubMed
    Score: 0.035
  18. Vannini F, Chattopadhyay M, Kodela R, Rao PPN, Kashfi K. Positional isomerism markedly affects the growth inhibition of colon cancer cells by NOSH-aspirin: COX inhibition and modeling. Redox Biol. 2015 Dec; 6:318-325.
    View in: PubMed
    Score: 0.035
  19. Kashfi K, Chattopadhyay M, Kodela R. NOSH-sulindac (AVT-18A) is a novel nitric oxide- and hydrogen sulfide-releasing hybrid that is gastrointestinal safe and has potent anti-inflammatory, analgesic, antipyretic, anti-platelet, and anti-cancer properties. Redox Biol. 2015 Dec; 6:287-296.
    View in: PubMed
    Score: 0.035
  20. Nath N, Chattopadhyay M, Rodes DB, Nazarenko A, Kodela R, Kashfi K. Nitric Oxide-Releasing Aspirin Suppresses NF-?B Signaling in Estrogen Receptor Negative Breast Cancer Cells in Vitro and in Vivo. Molecules. 2015 Jul 09; 20(7):12481-99.
    View in: PubMed
    Score: 0.035
  21. Kashfi K. Anti-cancer activity of new designer hydrogen sulfide-donating hybrids. Antioxid Redox Signal. 2014 Feb 10; 20(5):831-46.
    View in: PubMed
    Score: 0.030
  22. Kodela R, Chattopadhyay M, Goswami S, Gan ZY, Rao PP, Nia KV, Vel?zquez-Mart?nez CA, Kashfi K. Positional isomers of aspirin are equally potent in inhibiting colon cancer cell growth: differences in mode of cyclooxygenase inhibition. J Pharmacol Exp Ther. 2013 Apr; 345(1):85-94.
    View in: PubMed
    Score: 0.030
  23. Kashfi K, Olson KR. Biology and therapeutic potential of hydrogen sulfide and hydrogen sulfide-releasing chimeras. Biochem Pharmacol. 2013 Mar 01; 85(5):689-703.
    View in: PubMed
    Score: 0.029
  24. Chattopadhyay M, Kodela R, Olson KR, Kashfi K. NOSH-aspirin (NBS-1120), a novel nitric oxide- and hydrogen sulfide-releasing hybrid is a potent inhibitor of colon cancer cell growth in vitro and in a xenograft mouse model. Biochem Biophys Res Commun. 2012 Mar 16; 419(3):523-8.
    View in: PubMed
    Score: 0.028
  25. Chattopadhyay M, Kodela R, Nath N, Street CR, Vel?zquez-Mart?nez CA, Boring D, Kashfi K. Hydrogen sulfide-releasing aspirin modulates xenobiotic metabolizing enzymes in vitro and in vivo. Biochem Pharmacol. 2012 Mar 15; 83(6):733-40.
    View in: PubMed
    Score: 0.028
  26. Chattopadhyay M, Kodela R, Nath N, Barsegian A, Boring D, Kashfi K. Hydrogen sulfide-releasing aspirin suppresses NF-?B signaling in estrogen receptor negative breast cancer cells in vitro and in vivo. Biochem Pharmacol. 2012 Mar 15; 83(6):723-32.
    View in: PubMed
    Score: 0.028
  27. Kashfi K, Mynatt RL, Park EA, Cook GA. Membrane microenvironment regulation of carnitine palmitoyltranferases I and II. Biochem Soc Trans. 2011 Jun; 39(3):833-7.
    View in: PubMed
    Score: 0.026
  28. Chattopadhyay M, Velazquez CA, Pruski A, Nia KV, Abdellatif KR, Keefer LK, Kashfi K. Comparison between 3-Nitrooxyphenyl acetylsalicylate (NO-ASA) and O2-(acetylsalicyloxymethyl)-1-(pyrrolidin-1-yl)diazen-1-ium-1,2-diolate (NONO-ASA) as safe anti-inflammatory, analgesic, antipyretic, antioxidant prodrugs. J Pharmacol Exp Ther. 2010 Nov; 335(2):443-50.
    View in: PubMed
    Score: 0.025
  29. Chattopadhyay M, Goswami S, Rodes DB, Kodela R, Velazquez CA, Boring D, Crowell JA, Kashfi K. NO-releasing NSAIDs suppress NF-?B signaling in vitro and in vivo through S-nitrosylation. Cancer Lett. 2010 Dec 08; 298(2):204-11.
    View in: PubMed
    Score: 0.025
  30. Kashfi K. Anti-inflammatory agents as cancer therapeutics. Adv Pharmacol. 2009; 57:31-89.
    View in: PubMed
    Score: 0.024
  31. Kashfi K, Rigas B. Non-COX-2 targets and cancer: expanding the molecular target repertoire of chemoprevention. Biochem Pharmacol. 2005 Oct 01; 70(7):969-86.
    View in: PubMed
    Score: 0.018
  32. Kashfi K, Rigas B. Molecular targets of nitric-oxide-donating aspirin in cancer. Biochem Soc Trans. 2005 Aug; 33(Pt 4):701-4.
    View in: PubMed
    Score: 0.018
  33. Jeddi S, Kashfi K, Ghasemi A. The potential role of nitrate, a nitric oxide donor, in the prevention and treatment of diabetic osteoporosis. Front Endocrinol (Lausanne). 2025; 16:1480838.
    View in: PubMed
    Score: 0.017
  34. Farahani A, Farahani A, Kashfi K, Ghasemi A. Inducible nitric oxide synthase (iNOS): More than an inducible enzyme? Rethinking the classification of NOS isoforms. Pharmacol Res. 2025 Jun; 216:107781.
    View in: PubMed
    Score: 0.017
  35. Mousavi M, Moridi Farimani M, Kashfi K, Ghasemi A. Antidiabetic Potential of Sophora Species: Mechanisms, Bioactive Constituents, and Therapeutic Prospects. Planta Med. 2025 Sep; 91(10-11):546-557.
    View in: PubMed
    Score: 0.017
  36. Farahani A, Farahani A, Kashfi K, Ghasemi A. Inhibition of hepatic gluconeogenesis in type 2 diabetes by metformin: complementary role of nitric oxide. Med Gas Res. 2025 Dec 01; 15(4):507-519.
    View in: PubMed
    Score: 0.017
  37. Rigas B, Kashfi K. Cancer prevention: a new era beyond cyclooxygenase-2. J Pharmacol Exp Ther. 2005 Jul; 314(1):1-8.
    View in: PubMed
    Score: 0.017
  38. Bahadoran Z, Mirmiran P, Kashfi K, Ghasemi A. Effects of time-restricted feeding (TRF)-model of intermittent fasting on adipose organ: a narrative review. Eat Weight Disord. 2024 Dec 24; 29(1):77.
    View in: PubMed
    Score: 0.017
  39. Bahadoran Z, Mirmiran P, Hosseinpanah F, Kashfi K, Ghasemi A. Nitric oxide-based treatments improve wound healing associated with diabetes mellitus. Med Gas Res. 2025 Mar 01; 15(1):23-35.
    View in: PubMed
    Score: 0.016
  40. Rigas B, Kashfi K. Nitric-oxide-donating NSAIDs as agents for cancer prevention. Trends Mol Med. 2004 Jul; 10(7):324-30.
    View in: PubMed
    Score: 0.016
  41. Bagheripour F, Jeddi S, Kashfi K, Ghasemi A. Anti-obesity and anti-diabetic effects of L-citrulline are sex-dependent. Life Sci. 2024 Feb 15; 339:122432.
    View in: PubMed
    Score: 0.016
  42. Ghasemi A, Jeddi S, Yousefzadeh N, Kashfi K, Norouzirad R. Dissolving sodium hydrosulfide in drinking water is not a good source of hydrogen sulfide for animal studies. Sci Rep. 2023 12 09; 13(1):21839.
    View in: PubMed
    Score: 0.016
  43. Yassaghi Y, Jeddi S, Yousefzadeh N, Kashfi K, Ghasemi A. Long-term inorganic nitrate administration protects against myocardial ischemia-reperfusion injury in female rats. BMC Cardiovasc Disord. 2023 08 21; 23(1):411.
    View in: PubMed
    Score: 0.015
  44. Yousefzadeh N, Jeddi S, Zarkesh M, Norouzirad R, Kashfi K, Ghasemi A. Protective effects of long-term nitrate administration against ovariectomy-induced kidney dysfunction in rats. Pharmacol Rep. 2023 Aug; 75(4):979-994.
    View in: PubMed
    Score: 0.015
  45. Yousefzadeh N, Jeddi S, Zarkesh M, Kashfi K, Ghasemi A. Altered sialin mRNA gene expression in type 2 diabetic male Wistar rats: implications for nitric oxide deficiency. Sci Rep. 2023 03 10; 13(1):4013.
    View in: PubMed
    Score: 0.015
  46. Mohapatra S, Cafiero J, Kashfi K, Mehta P, Banerjee P. Why Don't the Mutant Cells That Evade DNA Repair Cause Cancer More Frequently? Importance of the Innate Immune System in the Tumor Microenvironment. Int J Mol Sci. 2023 Mar 06; 24(5).
    View in: PubMed
    Score: 0.015
  47. Bagheripour F, Jeddi S, Kashfi K, Ghasemi A. Metabolic effects of L-citrulline in type 2 diabetes. Acta Physiol (Oxf). 2023 03; 237(3):e13937.
    View in: PubMed
    Score: 0.015
  48. Yousefzadeh N, Jeddi S, Afzali H, Kashfi K, Ghasemi A. Chronic nitrate administration increases the expression the genes involved in the browning of white adipose tissue in female rats. Cell Biochem Funct. 2022 Oct; 40(7):750-759.
    View in: PubMed
    Score: 0.014
  49. Jeddi S, Gheibi S, Afzali H, Carlstr?m M, Kashfi K, Ghasemi A. Hydrogen sulfide potentiates the protective effects of nitrite against myocardial ischemia-reperfusion injury in type 2 diabetic rats. Nitric Oxide. 2022 07 01; 124:15-23.
    View in: PubMed
    Score: 0.014
  50. Jeddi S, Yousefzadeh N, Kashfi K, Ghasemi A. Role of nitric oxide in type 1 diabetes-induced osteoporosis. Biochem Pharmacol. 2022 03; 197:114888.
    View in: PubMed
    Score: 0.014
  51. Yousefzadeh N, Jeddi S, Shokri M, Afzali H, Norouzirad R, Kashfi K, Ghasemi A. Long Term Sodium Nitrate Administration Positively Impacts Metabolic and Obesity Indices in Ovariectomized Rats. Arch Med Res. 2022 02; 53(2):147-156.
    View in: PubMed
    Score: 0.014
  52. Baidoo JNE, Mukherjee S, Kashfi K, Banerjee P. A New Perspective on Cancer Therapy: Changing the Treaded Path? Int J Mol Sci. 2021 Sep 11; 22(18).
    View in: PubMed
    Score: 0.013
  53. Jeddi S, Gheibi S, Kashfi K, Ghasemi A. Sodium hydrosulfide has no additive effects on nitrite-inhibited renal gluconeogenesis in type 2 diabetic rats. Life Sci. 2021 Oct 15; 283:119870.
    View in: PubMed
    Score: 0.013
  54. Bahadoran Z, Mirmiran P, Kashfi K, Ghasemi A. Hyperuricemia-induced endothelial insulin resistance: the nitric oxide connection. Pflugers Arch. 2022 01; 474(1):83-98.
    View in: PubMed
    Score: 0.013
  55. Bahadoran Z, Mirmiran P, Kashfi K, Ghasemi A. Lost-in-Translation of Metabolic Effects of Inorganic Nitrate in Type 2 Diabetes: Is Ascorbic Acid the Answer? Int J Mol Sci. 2021 Apr 29; 22(9).
    View in: PubMed
    Score: 0.013
  56. Afzali H, Khaksari M, Jeddi S, Kashfi K, Abdollahifar MA, Ghasemi A. Acidified Nitrite Accelerates Wound Healing in Type 2 Diabetic Male Rats: A Histological and Stereological Evaluation. Molecules. 2021 Mar 26; 26(7).
    View in: PubMed
    Score: 0.013
  57. Shokri M, Jeddi S, Faridnouri H, Khorasani V, Kashfi K, Ghasemi A. Effect of Nitrate on Gene and Protein Expression of Nitric Oxide Synthase Enzymes in Insulin-Sensitive Tissues of Type 2 Diabetic Male Rats Endocr Metab Immune Disord Drug Targets. 2021; 21(12):2220-2230.
    View in: PubMed
    Score: 0.013
  58. Jeddi S, Gheibi S, Carlstr?m M, Kashfi K, Ghasemi A. Long-term co-administration of sodium nitrite and sodium hydrosulfide inhibits hepatic gluconeogenesis in male type 2 diabetic rats: Role of PI3K-Akt-eNOS pathway. Life Sci. 2021 Jan 15; 265:118770.
    View in: PubMed
    Score: 0.013
  59. Bahadoran Z, Mirmiran P, Kashfi K, Ghasemi A. Importance of Systematic Reviews and Meta-analyses of Animal Studies: Challenges for Animal-to-Human Translation. J Am Assoc Lab Anim Sci. 2020 09 01; 59(5):469-477.
    View in: PubMed
    Score: 0.012
  60. Afzali H, Khaksari M, Norouzirad R, Jeddi S, Kashfi K, Ghasemi A. Acidified nitrite improves wound healing in type 2 diabetic rats: Role of oxidative stress and inflammation. Nitric Oxide. 2020 10 01; 103:20-28.
    View in: PubMed
    Score: 0.012
  61. Iloun P, Hooshmandi E, Gheibi S, Kashfi K, Ghasemi R, Ahmadiani A. Roles and Interaction of the MAPK Signaling Cascade in A?25-35-Induced Neurotoxicity Using an Isolated Primary Hippocampal Cell Culture System. Cell Mol Neurobiol. 2021 Oct; 41(7):1497-1507.
    View in: PubMed
    Score: 0.012
  62. Jeddi S, Gheibi S, Kashfi K, Carlstr?m M, Ghasemi A. Protective effect of intermediate doses of hydrogen sulfide against myocardial ischemia-reperfusion injury in obese type 2 diabetic rats. Life Sci. 2020 Sep 01; 256:117855.
    View in: PubMed
    Score: 0.012
  63. Jeddi S, Gheibi S, Kashfi K, Carlstr?m M, Ghasemi A. Dose-Dependent Effects of Long-Term Administration of Hydrogen Sulfide on Myocardial Ischemia-Reperfusion Injury in Male Wistar Rats: Modulation of RKIP, NF-?B, and Oxidative Stress. Int J Mol Sci. 2020 Feb 19; 21(4).
    View in: PubMed
    Score: 0.012
  64. Salehi S, Kashfi K, Manaheji H, Haghparast A. Chemical stimulation of the lateral hypothalamus induces antiallodynic and anti-thermal hyperalgesic effects in animal model of neuropathic pain: Involvement of orexin receptors in the spinal cord. Brain Res. 2020 04 01; 1732:146674.
    View in: PubMed
    Score: 0.012
  65. Gheibi S, Jeddi S, Carlstr?m M, Kashfi K, Ghasemi A. Hydrogen sulfide potentiates the favorable metabolic effects of inorganic nitrite in type 2 diabetic rats. Nitric Oxide. 2019 11 01; 92:60-72.
    View in: PubMed
    Score: 0.012
  66. Jeddi S, Gholami H, Gheibi S, Kashfi K, Ghasemi A. Altered gene expression of hydrogen sulfide-producing enzymes in the liver and muscles tissues of hyperthyroid rats. J Cell Physiol. 2019 08; 234(10):17937-17945.
    View in: PubMed
    Score: 0.011
  67. Gheibi S, Jeddi S, Kashfi K, Ghasemi A. Effects of Hydrogen Sulfide on Carbohydrate Metabolism in Obese Type 2 Diabetic Rats. Molecules. 2019 Jan 06; 24(1).
    View in: PubMed
    Score: 0.011
  68. Bakhtiarzadeh F, Siavoshi F, Gheibi S, Kashfi K, Samadi R, Jeddi S, Ghasemi A. Effects of long-term oral nitrate administration on adiposity in normal adult female rats. Life Sci. 2018 Oct 01; 210:76-85.
    View in: PubMed
    Score: 0.011
  69. Gheibi S, Jeddi S, Kashfi K, Ghasemi A. Regulation of vascular tone homeostasis by NO and H2S: Implications in hypertension. Biochem Pharmacol. 2018 03; 149:42-59.
    View in: PubMed
    Score: 0.010
  70. Gheibi S, Kashfi K, Ghasemi A. A practical guide for induction of type-2 diabetes in rat: Incorporating a high-fat diet and streptozotocin. Biomed Pharmacother. 2017 Nov; 95:605-613.
    View in: PubMed
    Score: 0.010
  71. Vannini F, Kashfi K, Nath N. The dual role of iNOS in cancer. Redox Biol. 2015 Dec; 6:334-343.
    View in: PubMed
    Score: 0.009
  72. Jain S, Tran S, El Gendy MA, Kashfi K, Jurasz P, Vel?zquez-Mart?nez CA. Nitric oxide release is not required to decrease the ulcerogenic profile of nonsteroidal anti-inflammatory drugs. J Med Chem. 2012 Jan 26; 55(2):688-96.
    View in: PubMed
    Score: 0.007
  73. Ouyang N, Williams JL, Tsioulias GJ, Gao J, Iatropoulos MJ, Kopelovich L, Kashfi K, Rigas B. Nitric oxide-donating aspirin prevents pancreatic cancer in a hamster tumor model. Cancer Res. 2006 Apr 15; 66(8):4503-11.
    View in: PubMed
    Score: 0.005
  74. Gao J, Kashfi K, Liu X, Rigas B. NO-donating aspirin induces phase II enzymes in vitro and in vivo. Carcinogenesis. 2006 Apr; 27(4):803-10.
    View in: PubMed
    Score: 0.004
  75. Savle PS, Neptune NE, Yang Y, Rouden JH, Kite BL, Sugandhi EW, Macri RV, Kashfi K, Gandour RD. Comparison of (+)- and (-)-hemipalmitoylcarnitinium as inhibitors of hepatic mitochondrial carnitine palmitoyltransferases in diabetic rats. Med Chem. 2005 Sep; 1(5):445-53.
    View in: PubMed
    Score: 0.004
  76. Gao J, Kashfi K, Rigas B. In vitro metabolism of nitric oxide-donating aspirin: the effect of positional isomerism. J Pharmacol Exp Ther. 2005 Mar; 312(3):989-97.
    View in: PubMed
    Score: 0.004
  77. Williams JL, Kashfi K, Ouyang N, del Soldato P, Kopelovich L, Rigas B. NO-donating aspirin inhibits intestinal carcinogenesis in Min (APC(Min/+)) mice. Biochem Biophys Res Commun. 2004 Jan 16; 313(3):784-8.
    View in: PubMed
    Score: 0.004
  78. Kaza CS, Kashfi K, Rigas B. Colon cancer prevention with NO-releasing NSAIDs. Prostaglandins Other Lipid Mediat. 2002 Feb; 67(2):107-20.
    View in: PubMed
    Score: 0.003
Connection Strength

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