Chair of the Molecular Cellular and Biomedical Sciences Department
Molecular Cellular and Biomedical Sciences
University of Puerto Rico - Medical Science Campus
Yang L, Martin JH. Effects of motor cortex neuromodulation on the specificity of corticospinal tract spinal axon outgrowth and targeting in rats. Brain Stimul. 2023 May-Jun; 16(3):759-771.
Effects of motor cortex neuromodulation on the specificity of corticospinal tract spinal axon outgrowth and targeting in rats.
Sharif H, Alexander H, Azam A, Martin JH
Sharif H, Alexander H, Azam A, Martin JH. Dual motor cortex and spinal cord neuromodulation improves rehabilitation efficacy and restores skilled locomotor function in a rat cervical contusion injury model. Exp Neurol. 2021 07; 341:113715.
Dual motor cortex and spinal cord neuromodulation improves rehabilitation efficacy and restores skilled locomotor function in a rat cervical contusion injury model.
Williams PTJA, Schelbaum E, Ahmanna C, Alexander H, Kant? K, Soares S, Sharif H, Nothias F, Martin JH
Williams PTJA, Schelbaum E, Ahmanna C, Alexander H, Kant? K, Soares S, Sharif H, Nothias F, Martin JH. Combined biomaterial scaffold and neuromodulation strategy to promote tissue repair and corticospinal connectivity after spinal cord injury in a rodent model. Exp Neurol. 2024 Dec; 382:114965.
Combined biomaterial scaffold and neuromodulation strategy to promote tissue repair and corticospinal connectivity after spinal cord injury in a rodent model.
Zareen N, Yung H, Kaczetow W, Glattstein A, Mazalkova E, Alexander H, Chen L, Parra LC, Martin JH
Proceedings of the National Academy of Sciences of the United States of America
Zareen N, Yung H, Kaczetow W, Glattstein A, Mazalkova E, Alexander H, Chen L, Parra LC, Martin JH. Molecular signaling predicts corticospinal axon growth state and muscle response plasticity induced by neuromodulation. Proc Natl Acad Sci U S A. 2024 Nov 19; 121(47):e2408508121.
Molecular signaling predicts corticospinal axon growth state and muscle response plasticity induced by neuromodulation.
Developmental medicine and child neurology
Martin JH, Chakrabarty S, Friel KM. Harnessing activity-dependent plasticity to repair the damaged corticospinal tract in an animal model of cerebral palsy. Dev Med Child Neurol. 2011 Sep; 53 Suppl 4:9-13.
Harnessing activity-dependent plasticity to repair the damaged corticospinal tract in an animal model of cerebral palsy.
Tan AM, Chakrabarty S, Kimura H, Martin JH
The Journal of neuroscience : the official journal of the Society for Neuroscience
Tan AM, Chakrabarty S, Kimura H, Martin JH. Selective corticospinal tract injury in the rat induces primary afferent fiber sprouting in the spinal cord and hyperreflexia. J Neurosci. 2012 Sep 12; 32(37):12896-908.
Selective corticospinal tract injury in the rat induces primary afferent fiber sprouting in the spinal cord and hyperreflexia.
Williams PT, Martin JH. Motor Cortex Activity Organizes the Developing Rubrospinal System. J Neurosci. 2015 Sep 30; 35(39):13363-74.
Motor Cortex Activity Organizes the Developing Rubrospinal System.
Song W, Truong DQ, Bikson M, Martin JH. Transspinal direct current stimulation immediately modifies motor cortex sensorimotor maps. J Neurophysiol. 2015 Apr 01; 113(7):2801-11.
Transspinal direct current stimulation immediately modifies motor cortex sensorimotor maps.
Chakrabarty S, Martin J. Postnatal refinement of proprioceptive afferents in the cat cervical spinal cord. Eur J Neurosci. 2011 May; 33(9):1656-66.
Postnatal refinement of proprioceptive afferents in the cat cervical spinal cord.
Chakrabarty S, Martin JH. Co-development of proprioceptive afferents and the corticospinal tract within the cervical spinal cord. Eur J Neurosci. 2011 Sep; 34(5):682-94.
Co-development of proprioceptive afferents and the corticospinal tract within the cervical spinal cord.
Martin JH. Systems neurobiology of restorative neurology and future directions for repair of the damaged motor systems. Clin Neurol Neurosurg. 2012 Jun; 114(5):515-23.
Systems neurobiology of restorative neurology and future directions for repair of the damaged motor systems.
Williams PTJA, Jiang YQ, Martin JH. Motor system plasticity after unilateral injury in the developing brain. Dev Med Child Neurol. 2017 12; 59(12):1224-1229.
Motor system plasticity after unilateral injury in the developing brain.
Sharma M, Bhaskar V, Yang L, FallahRad M, Gebodh N, Zhang T, Esteller R, Martin J, Bikson M
Sharma M, Bhaskar V, Yang L, FallahRad M, Gebodh N, Zhang T, Esteller R, Martin J, Bikson M. Novel Evoked Synaptic Activity Potentials (ESAPs) Elicited by Spinal Cord Stimulation. eNeuro. 2023 05; 10(5).
Novel Evoked Synaptic Activity Potentials (ESAPs) Elicited by Spinal Cord Stimulation.
Zareen N, Dodson S, Armada K, Awad R, Sultana N, Hara E, Alexander H, Martin JH
Zareen N, Dodson S, Armada K, Awad R, Sultana N, Hara E, Alexander H, Martin JH. Stimulation-dependent remodeling of the corticospinal tract requires reactivation of growth-promoting developmental signaling pathways. Exp Neurol. 2018 09; 307:133-144.
Stimulation-dependent remodeling of the corticospinal tract requires reactivation of growth-promoting developmental signaling pathways.
Asante CO, Martin JH. Differential joint-specific corticospinal tract projections within the cervical enlargement. PLoS One. 2013; 8(9):e74454.
Differential joint-specific corticospinal tract projections within the cervical enlargement.
Bethea T, Adegbenro T, Martin JH. Hyperreflexia after corticospinal tract lesion reflects 1?A afferent circuit changes not increased KCC2 hyperexcitability. Exp Neurol. 2025 Dec; 394:115401.
Hyperreflexia after corticospinal tract lesion reflects 1?A afferent circuit changes not increased KCC2 hyperexcitability.
Friel KM, Chakrabarty S, Martin JH. Pathophysiological mechanisms of impaired limb use and repair strategies for motor systems after unilateral injury of the developing brain. Dev Med Child Neurol. 2013 Nov; 55 Suppl 4:27-31.
Pathophysiological mechanisms of impaired limb use and repair strategies for motor systems after unilateral injury of the developing brain.
Jiang YQ, Williams PT, Martin JH. Rapid and persistent impairments of the forelimb motor representations following cervical deafferentation in rats. Eur J Neurosci. 2013 Dec; 38(12):3702-11.
Rapid and persistent impairments of the forelimb motor representations following cervical deafferentation in rats.
Serradj N, Paix?o S, Sobocki T, Feinberg M, Klein R, Kullander K, Martin JH
Serradj N, Paix?o S, Sobocki T, Feinberg M, Klein R, Kullander K, Martin JH. EphA4-mediated ipsilateral corticospinal tract misprojections are necessary for bilateral voluntary movements but not bilateral stereotypic locomotion. J Neurosci. 2014 Apr 09; 34(15):5211-21.
EphA4-mediated ipsilateral corticospinal tract misprojections are necessary for bilateral voluntary movements but not bilateral stereotypic locomotion.
Williams PT, Kim S, Martin JH. Postnatal maturation of the red nucleus motor map depends on rubrospinal connections with forelimb motor pools. J Neurosci. 2014 Mar 19; 34(12):4432-41.
Postnatal maturation of the red nucleus motor map depends on rubrospinal connections with forelimb motor pools.
Song W, Amer A, Ryan D, Martin JH. Combined motor cortex and spinal cord neuromodulation promotes corticospinal system functional and structural plasticity and motor function after injury. Exp Neurol. 2016 Mar; 277:46-57.
Combined motor cortex and spinal cord neuromodulation promotes corticospinal system functional and structural plasticity and motor function after injury.
Martin JH. Harnessing neural activity to promote repair of the damaged corticospinal system after spinal cord injury. Neural Regen Res. 2016 Sep; 11(9):1389-1391.
Harnessing neural activity to promote repair of the damaged corticospinal system after spinal cord injury.
Serradj N, Martin JH. Motor Experience Reprograms Development of a Genetically-Altered Bilateral Corticospinal Motor Circuit. PLoS One. 2016; 11(9):e0163775.
Motor Experience Reprograms Development of a Genetically-Altered Bilateral Corticospinal Motor Circuit.
Jiang YQ, Zaaimi B, Martin JH. Competition with Primary Sensory Afferents Drives Remodeling of Corticospinal Axons in Mature Spinal Motor Circuits. J Neurosci. 2016 Jan 06; 36(1):193-203.
Competition with Primary Sensory Afferents Drives Remodeling of Corticospinal Axons in Mature Spinal Motor Circuits.
Jiang YQ, Armada K, Martin JH. Neuronal activity and microglial activation support corticospinal tract and proprioceptive afferent sprouting in spinal circuits after a corticospinal system lesion. Exp Neurol. 2019 11; 321:113015.
Neuronal activity and microglial activation support corticospinal tract and proprioceptive afferent sprouting in spinal circuits after a corticospinal system lesion.
Song W, Martin JH. Spinal cord direct current stimulation differentially modulates neuronal activity in the dorsal and ventral spinal cord. J Neurophysiol. 2017 03 01; 117(3):1143-1155.
Spinal cord direct current stimulation differentially modulates neuronal activity in the dorsal and ventral spinal cord.
Carmel JB, Kimura H, Martin JH. Electrical stimulation of motor cortex in the uninjured hemisphere after chronic unilateral injury promotes recovery of skilled locomotion through ipsilateral control. J Neurosci. 2014 Jan 08; 34(2):462-6.
Electrical stimulation of motor cortex in the uninjured hemisphere after chronic unilateral injury promotes recovery of skilled locomotion through ipsilateral control.
Martin JH. Neuroplasticity of spinal cord injury and repair. Handb Clin Neurol. 2022; 184:317-330.
Neuroplasticity of spinal cord injury and repair.
Amer A, Xia J, Smith M, Martin JH. Spinal cord representation of motor cortex plasticity reflects corticospinal tract LTP. Proc Natl Acad Sci U S A. 2021 12 28; 118(52).
Spinal cord representation of motor cortex plasticity reflects corticospinal tract LTP.
Williams PTJA, Truong DQ, Seifert AC, Xu J, Bikson M, Martin JH
Williams PTJA, Truong DQ, Seifert AC, Xu J, Bikson M, Martin JH. Selective augmentation of corticospinal motor drive with trans-spinal direct current stimulation in the cat. Brain Stimul. 2022 May-Jun; 15(3):624-634.
Selective augmentation of corticospinal motor drive with trans-spinal direct current stimulation in the cat.
Song W, Martin JH. Trans-Spinal Direct Current Stimulation Targets Ca2+ Channels to Induce Persistent Motor Unit Responses. Front Neurosci. 2022; 16:856948.
Trans-Spinal Direct Current Stimulation Targets Ca2+ Channels to Induce Persistent Motor Unit Responses.
Amer A, Martin JH. Repeated motor cortex theta-burst stimulation produces persistent strengthening of corticospinal motor output and durable spinal cord structural changes in the rat. Brain Stimul. 2022 Jul-Aug; 15(4):1013-1022.
Repeated motor cortex theta-burst stimulation produces persistent strengthening of corticospinal motor output and durable spinal cord structural changes in the rat.
Jiang YQ, Sarkar A, Amer A, Martin JH. Transneuronal Downregulation of the Premotor Cholinergic System After Corticospinal Tract Loss. J Neurosci. 2018 09 26; 38(39):8329-8344.
Transneuronal Downregulation of the Premotor Cholinergic System After Corticospinal Tract Loss.
El Seminario Internacional de Cuidadores de personas con Alzheimer