Methods in molecular biology (Clifton, N.J.)
Williams KP, Scott JE. Enzyme assay design for high-throughput screening. Methods Mol Biol. 2009; 565:107-26.
Enzyme assay design for high-throughput screening.
SLAS discovery : advancing life sciences R & D
Ahmad S, He Q, Williams KP, Scott JE. Identification of a Triple Drug Combination That Is Synergistically Cytotoxic for Triple-Negative Breast Cancer Cells Using a Novel Combination Discovery Approach. SLAS Discov. 2020 09; 25(8):923-938.
Identification of a Triple Drug Combination That Is Synergistically Cytotoxic for Triple-Negative Breast Cancer Cells Using a Novel Combination Discovery Approach.
Biomanufacturing Research Institute and Technology Enterprise (BRITE)
Biomanufacturing Research Institute and Technology Enterprise
College of Pharmacy and Pharmaceutical Sciences, Institute of Public Health
Small molecule inhibition of Rho GTPase activation to probe signaling cascades
Discovery of a Selective Agent that Activates PON1 Enzymatic Activity
Ahmad S, Wood KC, Scott JE. A high throughput proliferation and cytotoxicity assay for co-cultured isogenic cell lines. MethodsX. 2022; 9:101927.
A high throughput proliferation and cytotoxicity assay for co-cultured isogenic cell lines.
Biochemical and biophysical research communications
Kharabsheh HA, Scott JE. CoAsy knockdown in TNBC cell lines resulted in no overt effect on cell proliferation in?vitro. Biochem Biophys Res Commun. 2020 09 10; 530(1):136-141.
CoAsy knockdown in TNBC cell lines resulted in no overt effect on cell proliferation in?vitro.
Ahmad S, Carter JJ, Scott JE. A homogeneous cell-based assay for measurement of endogenous paraoxonase 1 activity. Anal Biochem. 2010 May 01; 400(1):1-9.
A homogeneous cell-based assay for measurement of endogenous paraoxonase 1 activity.
Ahmad S, Scott JE. Estradiol enhances cell-associated paraoxonase 1 (PON1) activity in vitro without altering PON1 expression. Biochem Biophys Res Commun. 2010 Jul 02; 397(3):441-6.
Estradiol enhances cell-associated paraoxonase 1 (PON1) activity in vitro without altering PON1 expression.
Ahmad S, Hughes MA, Lane KT, Redinbo MR, Yeh LA, Scott JE
Ahmad S, Hughes MA, Lane KT, Redinbo MR, Yeh LA, Scott JE. A High Throughput Assay for Discovery of Bacterial ?-Glucuronidase Inhibitors. Curr Chem Genomics. 2011; 5:13-20.
A High Throughput Assay for Discovery of Bacterial ?-Glucuronidase Inhibitors.
Ahmad S, Hughes MA, Yeh LA, Scott JE. Potential repurposing of known drugs as potent bacterial ?-glucuronidase inhibitors. J Biomol Screen. 2012 Aug; 17(7):957-65.
Potential repurposing of known drugs as potent bacterial ?-glucuronidase inhibitors.
Navarro H, Scott JE, Smith GR, Ghiabi P, Gibson E, Loppnau P, Harding RJ, Hossain MA, Bose MR, Pearce KH, Merten EM, Willson TM, Brown PJ
bioRxiv : the preprint server for biology
Navarro H, Scott JE, Smith GR, Ghiabi P, Gibson E, Loppnau P, Harding RJ, Hossain MA, Bose MR, Pearce KH, Merten EM, Willson TM, Brown PJ. Identification of Inhibitors of Chikungunya virus nsP2 ATPase. bioRxiv. 2025 Jan 14.
Identification of Inhibitors of Chikungunya virus nsP2 ATPase.
Graves TL, Zhang Y, Scott JE. A universal competitive fluorescence polarization activity assay for S-adenosylmethionine utilizing methyltransferases. Anal Biochem. 2008 Feb 15; 373(2):296-306.
A universal competitive fluorescence polarization activity assay for S-adenosylmethionine utilizing methyltransferases.
Graves TL, Scott JE. A high throughput serum paraoxonase assay for discovery of small molecule modulators of PON1 activity. Curr Chem Genomics. 2008 Nov 26; 2:51-61.
A high throughput serum paraoxonase assay for discovery of small molecule modulators of PON1 activity.
Ahmad S, Hughes MA, Johnson GL, Scott JE
Ahmad S, Hughes MA, Johnson GL, Scott JE. Development and validation of a high-throughput intrinsic ATPase activity assay for the discovery of MEKK2 inhibitors. J Biomol Screen. 2013 Apr; 18(4):388-99.
Development and validation of a high-throughput intrinsic ATPase activity assay for the discovery of MEKK2 inhibitors.
Kong R, Liu T, Zhu X, Ahmad S, Williams AL, Phan AT, Zhao H, Scott JE, Yeh LA, Wong ST
Clinical cancer research : an official journal of the American Association for Cancer Research
Kong R, Liu T, Zhu X, Ahmad S, Williams AL, Phan AT, Zhao H, Scott JE, Yeh LA, Wong ST. Old drug new use--amoxapine and its metabolites as potent bacterial ?-glucuronidase inhibitors for alleviating cancer drug toxicity. Clin Cancer Res. 2014 Jul 01; 20(13):3521-30.
Old drug new use--amoxapine and its metabolites as potent bacterial ?-glucuronidase inhibitors for alleviating cancer drug toxicity.
Ahmad S, Johnson GL, Scott JE. Identification of ponatinib and other known kinase inhibitors with?potent MEKK2 inhibitory activity. Biochem Biophys Res Commun. 2015 Aug 07; 463(4):888-93.
Identification of ponatinib and other known kinase inhibitors with?potent MEKK2 inhibitory activity.
Ahmad S, St Hilaire VR, Dandepally SR, Johnson GL, Williams AL, Scott JE
Ahmad S, St Hilaire VR, Dandepally SR, Johnson GL, Williams AL, Scott JE. Discovery and characterization of an iminocoumarin scaffold as an inhibitor of MEKK2 (MAP3K2). Biochem Biophys Res Commun. 2018 01 29; 496(1):205-211.
Discovery and characterization of an iminocoumarin scaffold as an inhibitor of MEKK2 (MAP3K2).
Tarpley M, Abdissa TT, Johnson GL, Scott JE
Tarpley M, Abdissa TT, Johnson GL, Scott JE. Bosutinib reduces the efficacy of Dasatinib in triple-negative breast cancer cell lines. Anticancer Res. 2014 Apr; 34(4):1629-35.
Bosutinib reduces the efficacy of Dasatinib in triple-negative breast cancer cell lines.
Molecular Biosciences and Bioengineering