Bradley Willcox to Longevity
This is a "connection" page, showing publications Bradley Willcox has written about Longevity.
Connection Strength
12.828
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Donlon TA, Morris BJ, Chen R, Lim E, Morgen EK, Fortney K, Shah N, Masaki KH, Willcox BJ. Proteomic basis of mortality resilience mediated by FOXO3 longevity genotype. Geroscience. 2023 08; 45(4):2303-2324.
Score: 0.674
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Donlon TA, Morris BJ, Masaki KH, Chen R, Davy PMC, Kallianpur KJ, Nakagawa K, Owens JB, Willcox DC, Allsopp RC, Willcox BJ. FOXO3, a Resilience Gene: Impact on Lifespan, Healthspan, and Deathspan. J Gerontol A Biol Sci Med Sci. 2022 08 12; 77(8):1479-1484.
Score: 0.648
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Morris BJ, Chen R, Donlon TA, Masaki KH, Willcox DC, Allsopp RC, Willcox BJ. Lifespan extension conferred by mitogen-activated protein kinase kinase kinase 5 (MAP3K5) longevity-associated gene variation is confined to at-risk men with a cardiometabolic disease. Aging (Albany NY). 2021 03 19; 13(6):7953-7974.
Score: 0.588
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Chen R, Morris BJ, Donlon TA, Masaki KH, Willcox DC, Davy PMC, Allsopp RC, Willcox BJ. FOXO3 longevity genotype mitigates the increased mortality risk in men with a cardiometabolic disease. Aging (Albany NY). 2020 12 01; 12(23):23509-23524.
Score: 0.576
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Donlon TA, Davy PMC, Willcox BJ. Analysis of FOXO3 Gene Polymorphisms Associated with Human Longevity. Methods Mol Biol. 2019; 1890:251-258.
Score: 0.505
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Donlon TA, Morris BJ, Chen R, Masaki KH, Allsopp RC, Willcox DC, Tiirikainen M, Willcox BJ. Analysis of Polymorphisms in 59 Potential Candidate Genes for Association With Human Longevity. J Gerontol A Biol Sci Med Sci. 2018 10 08; 73(11):1459-1464.
Score: 0.497
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Davy PMC, Willcox DC, Shimabukuro M, Donlon TA, Torigoe T, Suzuki M, Higa M, Masuzaki H, Sata M, Chen R, Murkofsky RL, Morris BJ, Lim E, Allsopp RC, Willcox BJ. Minimal Shortening of Leukocyte Telomere Length Across Age Groups in a Cross-Sectional Study for Carriers of a Longevity-Associated FOXO3 Allele. J Gerontol A Biol Sci Med Sci. 2018 10 08; 73(11):1448-1452.
Score: 0.497
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Davy PMC, Allsopp RC, Donlon TA, Morris BJ, Willcox DC, Willcox BJ. FOXO3 and Exceptional Longevity: Insights From Hydra to Humans. Curr Top Dev Biol. 2018; 127:193-212.
Score: 0.471
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Donlon TA, Morris BJ, He Q, Chen R, Masaki KH, Allsopp RC, Willcox DC, Tranah GJ, Parimi N, Evans DS, Flachsbart F, Nebel A, Kim DH, Park J, Willcox BJ. Association of Polymorphisms in Connective Tissue Growth Factor and Epidermal Growth Factor Receptor Genes With Human Longevity. J Gerontol A Biol Sci Med Sci. 2017 Aug 01; 72(8):1038-1044.
Score: 0.457
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Donlon TA, Morris BJ, Chen R, Masaki KH, Allsopp RC, Willcox DC, Elliott A, Willcox BJ. FOXO3 longevity interactome on chromosome 6. Aging Cell. 2017 10; 16(5):1016-1025.
Score: 0.456
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Willcox BJ, Willcox DC, Suzuki M. Demographic, phenotypic, and genetic characteristics of centenarians in Okinawa and Japan: Part 1-centenarians in Okinawa. Mech Ageing Dev. 2017 07; 165(Pt B):75-79.
Score: 0.435
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Morris BJ, Willcox DC, Donlon TA, Willcox BJ. FOXO3: A Major Gene for Human Longevity--A Mini-Review. Gerontology. 2015; 61(6):515-25.
Score: 0.389
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He Q, Morris BJ, Grove JS, Petrovitch H, Ross W, Masaki KH, Rodriguez B, Chen R, Donlon TA, Willcox DC, Willcox BJ. Shorter men live longer: association of height with longevity and FOXO3 genotype in American men of Japanese ancestry. PLoS One. 2014; 9(5):e94385.
Score: 0.365
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Bell CL, Chen R, Masaki K, Yee P, He Q, Grove J, Donlon T, Curb JD, Willcox DC, Poon LW, Willcox BJ. Late-life factors associated with healthy aging in older men. J Am Geriatr Soc. 2014 May; 62(5):880-8.
Score: 0.365
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Morris BJ, Donlon TA, He Q, Grove JS, Masaki KH, Elliott A, Willcox DC, Allsopp R, Willcox BJ. Genetic analysis of TOR complex gene variation with human longevity: a nested case-control study of American men of Japanese ancestry. J Gerontol A Biol Sci Med Sci. 2015 Feb; 70(2):133-42.
Score: 0.361
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Bendjilali N, Hsueh WC, He Q, Willcox DC, Nievergelt CM, Donlon TA, Kwok PY, Suzuki M, Willcox BJ. Who are the Okinawans? Ancestry, genome diversity, and implications for the genetic study of human longevity from a geographically isolated population. J Gerontol A Biol Sci Med Sci. 2014 Dec; 69(12):1474-84.
Score: 0.358
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Morris BJ, Donlon TA, He Q, Grove JS, Masaki KH, Elliott A, Willcox DC, Willcox BJ. Association analyses of insulin signaling pathway gene polymorphisms with healthy aging and longevity in Americans of Japanese ancestry. J Gerontol A Biol Sci Med Sci. 2014 Mar; 69(3):270-3.
Score: 0.343
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Willcox B. Successful aging: is there hope? CMAJ. 2012 Dec 11; 184(18):1973-4.
Score: 0.329
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Donlon TA, Curb JD, He Q, Grove JS, Masaki KH, Rodriguez B, Elliott A, Willcox DC, Willcox BJ. FOXO3 gene variants and human aging: coding variants may not be key players. J Gerontol A Biol Sci Med Sci. 2012 Nov; 67(11):1132-9.
Score: 0.316
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Willcox BJ, Willcox DC, Ferrucci L. Secrets of healthy aging and longevity from exceptional survivors around the globe: lessons from octogenarians to supercentenarians. J Gerontol A Biol Sci Med Sci. 2008 Nov; 63(11):1181-5.
Score: 0.249
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Willcox BJ, Donlon TA, He Q, Chen R, Grove JS, Yano K, Masaki KH, Willcox DC, Rodriguez B, Curb JD. FOXO3A genotype is strongly associated with human longevity. Proc Natl Acad Sci U S A. 2008 Sep 16; 105(37):13987-92.
Score: 0.247
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Abdi L, Lockwood G, Le Couteur D, Handelsman DJ, Naganathan V, Blyth F, Waite LM, Cogger V, Willcox B, Allsopp R. Protective effects of the FOXO3 gene in cardiometabolic disease in the Concord Health and Ageing in Men Project cohort. J Gerontol A Biol Sci Med Sci. 2026 Apr 07; 81(5).
Score: 0.209
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Willcox BJ, Willcox DC, He Q, Curb JD, Suzuki M. Siblings of Okinawan centenarians share lifelong mortality advantages. J Gerontol A Biol Sci Med Sci. 2006 Apr; 61(4):345-54.
Score: 0.208
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Martin P, Poon LW, Lee G, Obhi HK, Willcox BJ, Masaki KH. From 70 to 100: The Kuakini Hawaii Centenarian Study. J Gerontol A Biol Sci Med Sci. 2025 06 10; 80(7).
Score: 0.197
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Chen R, Morris BJ, Donlon TA, Nakagawa K, Allsopp RC, Willcox BJ, Masaki KH. FOXO3 Longevity Genotype Mitigates Risk Posed by Hypertension on Incident Coronary Artery Disease in Middle-Aged Men: Kuakini Honolulu Heart Program. J Gerontol A Biol Sci Med Sci. 2024 12 01; 79(12).
Score: 0.190
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Noureddine S, Schneider A, Strader S, Zhu X, Dhahbi J, Allsopp R, Willcox DC, Donlon TA, Shimabukuro M, Higa M, Suzuki M, Torigoe T, Ashiqueali S, Yadav H, Willcox BJ, Masternak MM. Circulating microRNA profile of long-lived Okinawans identifies novel potential targets for optimizing lifespan and health span. Aging Cell. 2024 08; 23(8):e14191.
Score: 0.183
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Harrison DE, Strong R, Reifsnyder P, Rosenthal N, Korstanje R, Fernandez E, Flurkey K, Ginsburg BC, Murrell MD, Javors MA, Lopez-Cruzan M, Nelson JF, Willcox BJ, Allsopp R, Watumull DM, Watumull DG, Cortopassi G, Kirkland JL, Tchkonia T, Choi YG, Yousefzadeh MJ, Robbins PD, Mitchell JR, Acar M, Sarnoski EA, Bene MR, Salmon A, Kumar N, Miller RA. Astaxanthin and meclizine extend lifespan in UM-HET3 male mice; fisetin, SG1002 (hydrogen sulfide donor), dimethyl fumarate, mycophenolic acid, and 4-phenylbutyrate do not significantly affect lifespan in either sex at the doses and schedules used. Geroscience. 2024 02; 46(1):795-816.
Score: 0.177
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Nakagawa K, Chen R, Ross GW, Donlon TA, Allsopp RC, Willcox DC, Morris BJ, Willcox BJ, Masaki KH. FOXO3 longevity genotype attenuates the impact of hypertension on cerebral microinfarct risk. J Hypertens. 2024 03 01; 42(3):484-489.
Score: 0.177
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Morris BJ, Chen R, Donlon TA, Kallianpur KJ, Masaki KH, Willcox BJ. Vascular endothelial growth factor receptor 1 gene (FLT1) longevity variant increases lifespan by reducing mortality risk posed by hypertension. Aging (Albany NY). 2023 05 12; 15(10):3967-3983.
Score: 0.171
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Orea-Soufi A, Paik J, Bragan?a J, Donlon TA, Willcox BJ, Link W. FOXO transcription factors as therapeutic targets in human diseases. Trends Pharmacol Sci. 2022 12; 43(12):1070-1084.
Score: 0.164
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Klinpudtan N, Allsopp RC, Kabayama M, Godai K, Gondo Y, Masui Y, Akagi Y, Srithumsuk W, Sugimoto K, Akasaka H, Takami Y, Takeya Y, Yamamoto K, Ikebe K, Yasumoto S, Ogawa M, Ishizaki T, Arai Y, Rakugi H, Chen R, Willcox BJ, Willcox DC, Kamide K. The Association Between Longevity-Associated FOXO3 Allele and Heart Disease in Septuagenarians and Octogenarians: The SONIC Study. J Gerontol A Biol Sci Med Sci. 2022 08 12; 77(8):1542-1548.
Score: 0.162
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Nakagawa K, Chen R, Greenberg SM, Ross GW, Willcox BJ, Donlon TA, Allsopp RC, Willcox DC, Morris BJ, Masaki KH. Forkhead box O3 longevity genotype may attenuate the impact of hypertension on risk of intracerebral haemorrhage. J Hypertens. 2022 11 01; 40(11):2230-2235.
Score: 0.162
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McIntyre RL, Liu YJ, Hu M, Morris BJ, Willcox BJ, Donlon TA, Houtkooper RH, Janssens GE. Pharmaceutical and nutraceutical activation of FOXO3 for healthy longevity. Ageing Res Rev. 2022 06; 78:101621.
Score: 0.158
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Frankum R, Jameson TSO, Knight BA, Stephens FB, Wall BT, Donlon TA, Torigoe T, Willcox BJ, Willcox DC, Allsopp RC, Harries LW. Extreme longevity variants at the FOXO3 locus may moderate FOXO3 isoform levels. Geroscience. 2022 04; 44(2):1129-1140.
Score: 0.152
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Donlon TA, Chen R, Masaki KH, Willcox BJ, Morris BJ. Association with Longevity of Phosphatidylinositol 3-Kinase Regulatory Subunit 1 Gene Variants Stems from Protection against Mortality Risk in Men with Cardiovascular Disease. Gerontology. 2022; 68(2):162-170.
Score: 0.149
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Donlon TA, Chen R, Masaki KH, Willcox DC, Allsopp RC, Willcox BJ, Morris BJ. Association of growth hormone receptor gene variant with longevity in men is due to amelioration of increased mortality risk from hypertension. Aging (Albany NY). 2021 06 01; 13(11):14745-14767.
Score: 0.149
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Donlon TA, Willcox BJ, Morris BJ. FOXO3 cell resilience gene neighborhood. Aging (Albany NY). 2017 Dec 14; 9(12):2467-2468.
Score: 0.117
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Willcox BJ, Morris BJ, Tranah GJ, Chen R, Masaki KH, He Q, Willcox DC, Allsopp RC, Moisyadi S, Gerschenson M, Davy PMC, Poon LW, Rodriguez B, Newman AB, Harris TB, Cummings SR, Liu Y, Parimi N, Evans DS, Donlon TA. Longevity-Associated FOXO3 Genotype and its Impact on Coronary Artery Disease Mortality in Japanese, Whites, and Blacks: A Prospective Study of Three American Populations. J Gerontol A Biol Sci Med Sci. 2017 May 01; 72(5):724-728.
Score: 0.112
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Morris BJ, Chen R, Donlon TA, Evans DS, Tranah GJ, Parimi N, Ehret GB, Newton-Cheh C, Seto T, Willcox DC, Masaki KH, Kamide K, Ryuno H, Oguro R, Nakama C, Kabayama M, Yamamoto K, Sugimoto K, Ikebe K, Masui Y, Arai Y, Ishizaki T, Gondo Y, Rakugi H, Willcox BJ. Association Analysis of FOXO3 Longevity Variants With Blood Pressure and Essential Hypertension. Am J Hypertens. 2016 11 01; 29(11):1292-1300.
Score: 0.109
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Martin P, Kelly N, Kahana B, Kahana E, Willcox BJ, Willcox DC, Poon LW. Defining successful aging: a tangible or elusive concept? Gerontologist. 2015 Feb; 55(1):14-25.
Score: 0.092
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Willcox DC, Scapagnini G, Willcox BJ. Healthy aging diets other than the Mediterranean: a focus on the Okinawan diet. Mech Ageing Dev. 2014 Mar-Apr; 136-137:148-62.
Score: 0.090
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Willcox BJ, Willcox DC. Caloric restriction, caloric restriction mimetics, and healthy aging in Okinawa: controversies and clinical implications. Curr Opin Clin Nutr Metab Care. 2014 Jan; 17(1):51-8.
Score: 0.089
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Anson RM, Willcox B, Austad S, Perls T. Within- and between-species study of extreme longevity--comments, commonalities, and goals. J Gerontol A Biol Sci Med Sci. 2012 Apr; 67(4):347-50.
Score: 0.079
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Rantanen T, Masaki K, He Q, Ross GW, Willcox BJ, White L. Midlife muscle strength and human longevity up to age 100 years: a 44-year prospective study among a decedent cohort. Age (Dordr). 2012 Jun; 34(3):563-70.
Score: 0.074
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Koropatnick TA, Kimbell J, Chen R, Grove JS, Donlon TA, Masaki KH, Rodriguez BL, Willcox BJ, Yano K, Curb JD. A prospective study of high-density lipoprotein cholesterol, cholesteryl ester transfer protein gene variants, and healthy aging in very old Japanese-american men. J Gerontol A Biol Sci Med Sci. 2008 Nov; 63(11):1235-40.
Score: 0.062
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Willcox DC, Willcox BJ, He Q, Wang NC, Suzuki M. They really are that old: a validation study of centenarian prevalence in Okinawa. J Gerontol A Biol Sci Med Sci. 2008 Apr; 63(4):338-49.
Score: 0.060
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Willcox DC, Willcox BJ, Todoriki H, Curb JD, Suzuki M. Caloric restriction and human longevity: what can we learn from the Okinawans? Biogerontology. 2006 Jun; 7(3):173-7.
Score: 0.053
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Bernstein AM, Willcox BJ, Tamaki H, Kunishima N, Suzuki M, Willcox DC, Yoo JS, Perls TT. First autopsy study of an Okinawan centenarian: absence of many age-related diseases. J Gerontol A Biol Sci Med Sci. 2004 Nov; 59(11):1195-9.
Score: 0.047
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Olshansky SJ, Willcox BJ, Demetrius L, Beltr?n-S?nchez H. Implausibility of radical life extension in humans in the twenty-first century. Nat Aging. 2024 Nov; 4(11):1635-1642.
Score: 0.047
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Morris BJ, Willcox BJ, Donlon TA. Genetic and epigenetic regulation of human aging and longevity. Biochim Biophys Acta Mol Basis Dis. 2019 07 01; 1865(7):1718-1744.
Score: 0.031
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Willcox DC, Willcox BJ, Todoriki H, Suzuki M. The Okinawan diet: health implications of a low-calorie, nutrient-dense, antioxidant-rich dietary pattern low in glycemic load. J Am Coll Nutr. 2009 Aug; 28 Suppl:500S-516S.
Score: 0.016
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Willcox DC, Willcox BJ, Sokolovsky J, Sakihara S. The cultural context of "successful aging" among older women weavers in a northern Okinawan village: the role of productive activity. J Cross Cult Gerontol. 2007 Jun; 22(2):137-65.
Score: 0.014