Olivier Le Saux to Multidrug Resistance-Associated Proteins
This is a "connection" page, showing publications Olivier Le Saux has written about Multidrug Resistance-Associated Proteins.
Connection Strength
5.020
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Shimada BK, Pomozi V, Zoll J, Kuo S, Martin L, Le Saux O. ABCC6, Pyrophosphate and Ectopic Calcification: Therapeutic Solutions. Int J Mol Sci. 2021 Apr 27; 22(9).
Score: 0.786
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Brampton C, Pomozi V, Chen LH, Apana A, McCurdy S, Zoll J, Boisvert WA, Lambert G, Henrion D, Blanchard S, Kuo S, Leftheriotis G, Martin L, Le Saux O. ABCC6 deficiency promotes dyslipidemia and atherosclerosis. Sci Rep. 2021 02 16; 11(1):3881.
Score: 0.776
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Pomozi V, Brampton C, Szeri F, Dedinszki D, Koz?k E, van de Wetering K, Hopkins H, Martin L, V?radi A, Le Saux O. Functional Rescue of ABCC6 Deficiency by 4-Phenylbutyrate Therapy Reduces Dystrophic Calcification in Abcc6-/- Mice. J Invest Dermatol. 2017 03; 137(3):595-602.
Score: 0.577
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Brampton C, Aherrahrou Z, Chen LH, Martin L, Bergen AA, Gorgels TG, Erdmann J, Erdfdi J, Schunkert H, Szab? Z, V?radi A, Le Saux O. The level of hepatic ABCC6 expression determines the severity of calcification after cardiac injury. Am J Pathol. 2014 Jan; 184(1):159-70.
Score: 0.474
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Le Saux O, F?l?p K, Yamaguchi Y, Ili?s A, Szab? Z, Brampton CN, Pomozi V, Husz?r K, Ar?nyi T, V?radi A. Expression and in vivo rescue of human ABCC6 disease-causing mutants in mouse liver. PLoS One. 2011; 6(9):e24738.
Score: 0.404
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Le Saux O, Bunda S, VanWart CM, Douet V, Got L, Martin L, Hinek A. Serum factors from pseudoxanthoma elasticum patients alter elastic fiber formation in vitro. J Invest Dermatol. 2006 Jul; 126(7):1497-505.
Score: 0.276
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De Vilder EYG, Cardoen S, Hosen MJ, Le Saux O, De Zaeytijd J, Leroy BP, De Reuck J, Coucke PJ, De Paepe A, Hemelsoet D, Vanakker OM. Pathogenic variants in the ABCC6 gene are associated with an increased risk for ischemic stroke. Brain Pathol. 2018 11; 28(6):822-831.
Score: 0.165
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Letavernier E, Kauffenstein G, Huguet L, Navasiolava N, Bouderlique E, Tang E, Delaitre L, Bazin D, de Frutos M, Gay C, Perez J, Verpont MC, Haymann JP, Pomozi V, Zoll J, Le Saux O, Daudon M, Leftheriotis G, Martin L. ABCC6 Deficiency Promotes Development of Randall Plaque. J Am Soc Nephrol. 2018 09; 29(9):2337-2347.
Score: 0.162
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Kauffenstein G, Yegutkin GG, Khiati S, Pomozi V, Le Saux O, Leftheriotis G, Lenaers G, Henrion D, Martin L. Alteration of Extracellular Nucleotide Metabolism in Pseudoxanthoma Elasticum. J Invest Dermatol. 2018 08; 138(8):1862-1870.
Score: 0.158
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Favre G, Laurain A, Aranyi T, Szeri F, Fulop K, Le Saux O, Duranton C, Kauffenstein G, Martin L, Lefth?riotis G. The ABCC6 Transporter: A New Player in Biomineralization. Int J Mol Sci. 2017 Sep 11; 18(9).
Score: 0.153
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Pomozi V, Brampton C, van de Wetering K, Zoll J, Calio B, Pham K, Owens JB, Marh J, Moisyadi S, V?radi A, Martin L, Bauer C, Erdmann J, Aherrahrou Z, Le Saux O. Pyrophosphate Supplementation Prevents Chronic and Acute Calcification in ABCC6-Deficient Mice. Am J Pathol. 2017 Jun; 187(6):1258-1272.
Score: 0.149
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Pomozi V, Brampton C, F?l?p K, Chen LH, Apana A, Li Q, Uitto J, Le Saux O, V?radi A. Analysis of pseudoxanthoma elasticum-causing missense mutants of ABCC6 in vivo; pharmacological correction of the mislocalized proteins. J Invest Dermatol. 2014 Apr; 134(4):946-953.
Score: 0.117
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Pomozi V, Le Saux O, Brampton C, Apana A, Ili?s A, Szeri F, Martin L, Monostory K, Paku S, Sarkadi B, Szak?cs G, V?radi A. ABCC6 is a basolateral plasma membrane protein. Circ Res. 2013 May 24; 112(11):e148-51.
Score: 0.113
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Brampton C, Yamaguchi Y, Vanakker O, Van Laer L, Chen LH, Thakore M, De Paepe A, Pomozi V, Szab? PT, Martin L, V?radi A, Le Saux O. Vitamin K does not prevent soft tissue mineralization in a mouse model of pseudoxanthoma elasticum. Cell Cycle. 2011 Jun 01; 10(11):1810-20.
Score: 0.099
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Martin L, Douet V, VanWart CM, Heller MB, Le Saux O. A mouse model of ?-thalassemia shows a liver-specific down-regulation of Abcc6 expression. Am J Pathol. 2011 Feb; 178(2):774-83.
Score: 0.097
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Costrop LM, Vanakker OO, Van Laer L, Le Saux O, Martin L, Chassaing N, Guerra D, Pasquali-Ronchetti I, Coucke PJ, De Paepe A. Novel deletions causing pseudoxanthoma elasticum underscore the genomic instability of the ABCC6 region. J Hum Genet. 2010 Feb; 55(2):112-7.
Score: 0.090
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Martin L, Ma?tre F, Bonicel P, Daudon P, Verny C, Bonneau D, Le Saux O, Chassaing N. Heterozygosity for a single mutation in the ABCC6 gene may closely mimic PXE: consequences of this phenotype overlap for the definition of PXE. Arch Dermatol. 2008 Mar; 144(3):301-6.
Score: 0.079
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Douet V, Heller MB, Le Saux O. DNA methylation and Sp1 binding determine the tissue-specific transcriptional activity of the mouse Abcc6 promoter. Biochem Biophys Res Commun. 2007 Mar 02; 354(1):66-71.
Score: 0.073
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Douet V, VanWart CM, Heller MB, Reinhard S, Le Saux O. HNF4alpha and NF-E2 are key transcriptional regulators of the murine Abcc6 gene expression. Biochim Biophys Acta. 2006 Aug-Sep; 1759(8-9):426-36.
Score: 0.071
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Beck K, Hayashi K, Nishiguchi B, Le Saux O, Hayashi M, Boyd CD. The distribution of Abcc6 in normal mouse tissues suggests multiple functions for this ABC transporter. J Histochem Cytochem. 2003 Jul; 51(7):887-902.
Score: 0.057
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Ili?s A, Urb?n Z, Seidl TL, Le Saux O, Sink? E, Boyd CD, Sarkadi B, V?radi A. Loss of ATP-dependent transport activity in pseudoxanthoma elasticum-associated mutants of human ABCC6 (MRP6). J Biol Chem. 2002 May 10; 277(19):16860-7.
Score: 0.052
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Dedinszki D, Szeri F, Koz?k E, Pomozi V, Tok?si N, Mezei TR, Merczel K, Letavernier E, Tang E, Le Saux O, Ar?nyi T, van de Wetering K, V?radi A. Oral administration of pyrophosphate inhibits connective tissue calcification. EMBO Mol Med. 2017 11; 9(11):1463-1470.
Score: 0.039
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Prunier F, Terrien G, Le Corre Y, Apana AL, Bi?re L, Kauffenstein G, Furber A, Bergen AA, Gorgels TG, Le Saux O, Leftheriotis G, Martin L. Pseudoxanthoma elasticum: cardiac findings in patients and Abcc6-deficient mouse model. PLoS One. 2013; 8(7):e68700.
Score: 0.029
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Le Corre Y, Le Saux O, Froeliger F, Libouban H, Kauffenstein G, Willoteaux S, Leftheriotis G, Martin L. Quantification of the calcification phenotype of Abcc6-deficient mice with microcomputed tomography. Am J Pathol. 2012 Jun; 180(6):2208-13.
Score: 0.026