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Connection

Olivier Le Saux to Humans

This is a "connection" page, showing publications Olivier Le Saux has written about Humans.
Connection Strength

0.363
  1. Brampton C, Pomozi V, Le Corre Y, Zoll J, Kauffenstein G, Ma C, Hoffmann PR, Martin L, Le Saux O. Bone Marrow-Derived ABCC6 Is an Essential Regulator of Ectopic Calcification In Pseudoxanthoma Elasticum. J Invest Dermatol. 2024 Aug; 144(8):1772-1783.e3.
    View in: PubMed
    Score: 0.044
  2. Shimada BK, Pomozi V, Zoll J, Kuo S, Martin L, Le Saux O. ABCC6, Pyrophosphate and Ectopic Calcification: Therapeutic Solutions. Int J Mol Sci. 2021 Apr 27; 22(9).
    View in: PubMed
    Score: 0.037
  3. Brampton C, Pomozi V, Chen LH, Apana A, McCurdy S, Zoll J, Boisvert WA, Lambert G, Henrion D, Blanchard S, Kuo S, Leftheriotis G, Martin L, Le Saux O. ABCC6 deficiency promotes dyslipidemia and atherosclerosis. Sci Rep. 2021 02 16; 11(1):3881.
    View in: PubMed
    Score: 0.036
  4. Pomozi V, Julian CB, Zoll J, Pham K, Kuo S, Tok?si N, Martin L, V?radi A, Le Saux O. Dietary Pyrophosphate Modulates Calcification in a Mouse Model of Pseudoxanthoma Elasticum: Implication for Treatment of Patients. J Invest Dermatol. 2019 05; 139(5):1082-1088.
    View in: PubMed
    Score: 0.031
  5. Pomozi V, Brampton C, Szeri F, Dedinszki D, Koz?k E, van de Wetering K, Hopkins H, Martin L, V?radi A, Le Saux O. Functional Rescue of ABCC6 Deficiency by 4-Phenylbutyrate Therapy Reduces Dystrophic Calcification in Abcc6-/- Mice. J Invest Dermatol. 2017 03; 137(3):595-602.
    View in: PubMed
    Score: 0.027
  6. Brampton C, Aherrahrou Z, Chen LH, Martin L, Bergen AA, Gorgels TG, Erdmann J, Erdfdi J, Schunkert H, Szab? Z, V?radi A, Le Saux O. The level of hepatic ABCC6 expression determines the severity of calcification after cardiac injury. Am J Pathol. 2014 Jan; 184(1):159-70.
    View in: PubMed
    Score: 0.022
  7. Le Saux O, F?l?p K, Yamaguchi Y, Ili?s A, Szab? Z, Brampton CN, Pomozi V, Husz?r K, Ar?nyi T, V?radi A. Expression and in vivo rescue of human ABCC6 disease-causing mutants in mouse liver. PLoS One. 2011; 6(9):e24738.
    View in: PubMed
    Score: 0.019
  8. Douet V, VanWart CM, Heller MB, Reinhard S, Le Saux O. HNF4alpha and NF-E2 are key transcriptional regulators of the murine Abcc6 gene expression. Biochim Biophys Acta. 2006 Aug-Sep; 1759(8-9):426-36.
    View in: PubMed
    Score: 0.013
  9. Le Saux O, Bunda S, VanWart CM, Douet V, Got L, Martin L, Hinek A. Serum factors from pseudoxanthoma elasticum patients alter elastic fiber formation in vitro. J Invest Dermatol. 2006 Jul; 126(7):1497-505.
    View in: PubMed
    Score: 0.013
  10. Hamlin N, Beck K, Bacchelli B, Cianciulli P, Pasquali-Ronchetti I, Le Saux O. Acquired Pseudoxanthoma elasticum-like syndrome in beta-thalassaemia patients. Br J Haematol. 2003 Sep; 122(5):852-4.
    View in: PubMed
    Score: 0.011
  11. Le Saux O, Beck K, Sachsinger C, Treiber C, G?ring HH, Curry K, Johnson EW, Bercovitch L, Marais AS, Terry SF, Viljoen DL, Boyd CD. Evidence for a founder effect for pseudoxanthoma elasticum in the Afrikaner population of South Africa. Hum Genet. 2002 Oct; 111(4-5):331-8.
    View in: PubMed
    Score: 0.010
  12. Panee J, Pomozi V, Franke AA, Le Saux O, Gerschenson M. Chronic marijuana use moderates the correlations of serum cholesterol with systemic mitochondrial function and fluid cognition. Mitochondrion. 2020 05; 52:135-143.
    View in: PubMed
    Score: 0.008
  13. De Vilder EYG, Cardoen S, Hosen MJ, Le Saux O, De Zaeytijd J, Leroy BP, De Reuck J, Coucke PJ, De Paepe A, Hemelsoet D, Vanakker OM. Pathogenic variants in the ABCC6 gene are associated with an increased risk for ischemic stroke. Brain Pathol. 2018 11; 28(6):822-831.
    View in: PubMed
    Score: 0.008
  14. Letavernier E, Kauffenstein G, Huguet L, Navasiolava N, Bouderlique E, Tang E, Delaitre L, Bazin D, de Frutos M, Gay C, Perez J, Verpont MC, Haymann JP, Pomozi V, Zoll J, Le Saux O, Daudon M, Leftheriotis G, Martin L. ABCC6 Deficiency Promotes Development of Randall Plaque. J Am Soc Nephrol. 2018 09; 29(9):2337-2347.
    View in: PubMed
    Score: 0.008
  15. Kauffenstein G, Yegutkin GG, Khiati S, Pomozi V, Le Saux O, Leftheriotis G, Lenaers G, Henrion D, Martin L. Alteration of Extracellular Nucleotide Metabolism in Pseudoxanthoma Elasticum. J Invest Dermatol. 2018 08; 138(8):1862-1870.
    View in: PubMed
    Score: 0.007
  16. Dedinszki D, Szeri F, Koz?k E, Pomozi V, Tok?si N, Mezei TR, Merczel K, Letavernier E, Tang E, Le Saux O, Ar?nyi T, van de Wetering K, V?radi A. Oral administration of pyrophosphate inhibits connective tissue calcification. EMBO Mol Med. 2017 11; 9(11):1463-1470.
    View in: PubMed
    Score: 0.007
  17. Favre G, Laurain A, Aranyi T, Szeri F, Fulop K, Le Saux O, Duranton C, Kauffenstein G, Martin L, Lefth?riotis G. The ABCC6 Transporter: A New Player in Biomineralization. Int J Mol Sci. 2017 Sep 11; 18(9).
    View in: PubMed
    Score: 0.007
  18. Leftheriotis G, Kauffenstein G, Hamel JF, Abraham P, Le Saux O, Willoteaux S, Henrion D, Martin L. The contribution of arterial calcification to peripheral arterial disease in pseudoxanthoma elasticum. PLoS One. 2014; 9(5):e96003.
    View in: PubMed
    Score: 0.006
  19. Hosen MJ, Coucke PJ, Le Saux O, De Paepe A, Vanakker OM. Perturbation of specific pro-mineralizing signalling pathways in human and murine pseudoxanthoma elasticum. Orphanet J Rare Dis. 2014 Apr 29; 9:66.
    View in: PubMed
    Score: 0.006
  20. Pomozi V, Brampton C, F?l?p K, Chen LH, Apana A, Li Q, Uitto J, Le Saux O, V?radi A. Analysis of pseudoxanthoma elasticum-causing missense mutants of ABCC6 in vivo; pharmacological correction of the mislocalized proteins. J Invest Dermatol. 2014 Apr; 134(4):946-953.
    View in: PubMed
    Score: 0.005
  21. Prunier F, Terrien G, Le Corre Y, Apana AL, Bi?re L, Kauffenstein G, Furber A, Bergen AA, Gorgels TG, Le Saux O, Leftheriotis G, Martin L. Pseudoxanthoma elasticum: cardiac findings in patients and Abcc6-deficient mouse model. PLoS One. 2013; 8(7):e68700.
    View in: PubMed
    Score: 0.005
  22. Pomozi V, Le Saux O, Brampton C, Apana A, Ili?s A, Szeri F, Martin L, Monostory K, Paku S, Sarkadi B, Szak?cs G, V?radi A. ABCC6 is a basolateral plasma membrane protein. Circ Res. 2013 May 24; 112(11):e148-51.
    View in: PubMed
    Score: 0.005
  23. Le Corre Y, Le Saux O, Froeliger F, Libouban H, Kauffenstein G, Willoteaux S, Leftheriotis G, Martin L. Quantification of the calcification phenotype of Abcc6-deficient mice with microcomputed tomography. Am J Pathol. 2012 Jun; 180(6):2208-13.
    View in: PubMed
    Score: 0.005
  24. Lefth?riotis G, Abraham P, Le Corre Y, Le Saux O, Henrion D, Ducluzeau PH, Prunier F, Martin L. Relationship between ankle brachial index and arterial remodeling in pseudoxanthoma elasticum. J Vasc Surg. 2011 Nov; 54(5):1390-4.
    View in: PubMed
    Score: 0.005
  25. Lefth?riotis G, Vanakker O, Le Saux O, Martin L. Reply to the article of C. Markello et al. entitled "Vascular pathology of medial arterial calcifications in NT5E deficiency: Implications for the role of adenosine in pseudoxanthoma elasticum". Mol Genet Metab. 2011 Jun; 103(2):199-200.
    View in: PubMed
    Score: 0.005
  26. Costrop LM, Vanakker OO, Van Laer L, Le Saux O, Martin L, Chassaing N, Guerra D, Pasquali-Ronchetti I, Coucke PJ, De Paepe A. Novel deletions causing pseudoxanthoma elasticum underscore the genomic instability of the ABCC6 region. J Hum Genet. 2010 Feb; 55(2):112-7.
    View in: PubMed
    Score: 0.004
  27. Martin L, Ma?tre F, Bonicel P, Daudon P, Verny C, Bonneau D, Le Saux O, Chassaing N. Heterozygosity for a single mutation in the ABCC6 gene may closely mimic PXE: consequences of this phenotype overlap for the definition of PXE. Arch Dermatol. 2008 Mar; 144(3):301-6.
    View in: PubMed
    Score: 0.004
  28. Beck K, Hayashi K, Nishiguchi B, Le Saux O, Hayashi M, Boyd CD. The distribution of Abcc6 in normal mouse tissues suggests multiple functions for this ABC transporter. J Histochem Cytochem. 2003 Jul; 51(7):887-902.
    View in: PubMed
    Score: 0.003
  29. Ili?s A, Urb?n Z, Seidl TL, Le Saux O, Sink? E, Boyd CD, Sarkadi B, V?radi A. Loss of ATP-dependent transport activity in pseudoxanthoma elasticum-associated mutants of human ABCC6 (MRP6). J Biol Chem. 2002 May 10; 277(19):16860-7.
    View in: PubMed
    Score: 0.002
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
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