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Connection

Xioxin Chen to Humans

This is a "connection" page, showing publications Xioxin Chen has written about Humans.
Connection Strength

0.685
  1. Li Y, Li Y, Chen X. NOTCH and Esophageal Squamous Cell Carcinoma. Adv Exp Med Biol. 2021; 1287:59-68.
    View in: PubMed
    Score: 0.036
  2. Yang CS, Chen XL. Research on esophageal cancer: With personal perspectives from studies in China and Kenya. Int J Cancer. 2021 07 15; 149(2):264-276.
    View in: PubMed
    Score: 0.036
  3. Odera JO, Xiong Z, Huang C, Gu N, Yang W, Githang'a J, Odera E, Paiboonrungruang C, Chen X. NRF2/ACSS2 axis mediates the metabolic effect of alcohol drinking on esophageal squamous cell carcinoma. Biochem J. 2020 08 28; 477(16):3075-3089.
    View in: PubMed
    Score: 0.035
  4. Fu J, Xiong Z, Huang C, Li J, Yang W, Han Y, Paiboonrungruan C, Major MB, Chen KN, Kang X, Chen X. Hyperactivity of the transcription factor Nrf2 causes metabolic reprogramming in mouse esophagus. J Biol Chem. 2019 01 04; 294(1):327-340.
    View in: PubMed
    Score: 0.031
  5. Ma S, Paiboonrungruan C, Yan T, Williams KP, Major MB, Chen XL. Targeted therapy of esophageal squamous cell carcinoma: the NRF2 signaling pathway as target. Ann N Y Acad Sci. 2018 12; 1434(1):164-172.
    View in: PubMed
    Score: 0.030
  6. Ma S, Yan T, Liu D, Wang K, Wang J, Song J, Wang T, He W, Bai J, Jin L, Chen X. Neoadjuvant chemotherapy followed by minimally invasive esophagectomy is safe and feasible for treatment of esophageal squamous cell carcinoma. Thorac Cancer. 2018 02; 9(2):310-315.
    View in: PubMed
    Score: 0.029
  7. Xiong Z, Ren S, Chen H, Liu Y, Huang C, Zhang YL, Odera JO, Chen T, Kist R, Peters H, Garman K, Sun Z, Chen X. PAX9 regulates squamous cell differentiation and carcinogenesis in the oro-oesophageal epithelium. J Pathol. 2018 02; 244(2):164-175.
    View in: PubMed
    Score: 0.029
  8. Liu Y, Xiong Z, Beasley A, D'Amico T, Chen XL. Personalized and targeted therapy of esophageal squamous cell carcinoma: an update. Ann N Y Acad Sci. 2016 10; 1381(1):66-73.
    View in: PubMed
    Score: 0.026
  9. Chen H, Beasley A, Hu Y, Chen X. A Zebrafish Model for Studies on Esophageal Epithelial Biology. PLoS One. 2015; 10(12):e0143878.
    View in: PubMed
    Score: 0.025
  10. Liu Y, Chen H, Sun Z, Chen X. Molecular mechanisms of ethanol-associated oro-esophageal squamous cell carcinoma. Cancer Lett. 2015 Jun 01; 361(2):164-73.
    View in: PubMed
    Score: 0.024
  11. Bellizzi AM, Nardone G, Compare D, Bor S, Capanoglu D, Farr? R, Neumann H, Neurath MF, Vieth M, Chen H, Chen X. Tissue resistance in the normal and diseased esophagus. Ann N Y Acad Sci. 2013 Oct; 1300:200-212.
    View in: PubMed
    Score: 0.022
  12. Ren D, Zheng G, Bream S, Tevebaugh W, Shaheen NJ, Chen X. Single nucleotide polymorphisms of caudal type homeobox 1 and 2 are associated with Barrett's esophagus. Dig Dis Sci. 2014 Jan; 59(1):57-63.
    View in: PubMed
    Score: 0.021
  13. Chen H, Hu Y, Fang Y, Djukic Z, Yamamoto M, Shaheen NJ, Orlando RC, Chen X. Nrf2 deficiency impairs the barrier function of mouse oesophageal epithelium. Gut. 2014 May; 63(5):711-9.
    View in: PubMed
    Score: 0.021
  14. Chen H, Fang Y, Tevebaugh W, Orlando RC, Shaheen NJ, Chen X. Molecular mechanisms of Barrett's esophagus. Dig Dis Sci. 2011 Dec; 56(12):3405-20.
    View in: PubMed
    Score: 0.019
  15. Wang J, Qin R, Ma Y, Wu H, Peters H, Tyska M, Shaheen NJ, Chen X. Differential gene expression in normal esophagus and Barrett's esophagus. J Gastroenterol. 2009; 44(9):897-911.
    View in: PubMed
    Score: 0.016
  16. Chen X, Qin R, Liu B, Ma Y, Su Y, Yang CS, Glickman JN, Odze RD, Shaheen NJ. Multilayered epithelium in a rat model and human Barrett's esophagus: similar expression patterns of transcription factors and differentiation markers. BMC Gastroenterol. 2008 Jan 11; 8:1.
    View in: PubMed
    Score: 0.015
  17. Sun Z, Sood S, Li N, Yang P, Newman RA, Yang CS, Chen X. Chemoprevention of 7,12-dimethylbenz[a]anthracene (DMBA)-induced oral carcinogenesis in hamster cheek pouch by topical application of a dual inhibitor of epidermal growth factor receptor (EGFR) and ErbB2 tyrosine kinases. Oral Oncol. 2008 Jul; 44(7):652-7.
    View in: PubMed
    Score: 0.014
  18. Zhang X, Yang F, Shim JY, Kirk KL, Anderson DE, Chen X. Identification of arsenic-binding proteins in human breast cancer cells. Cancer Lett. 2007 Sep 18; 255(1):95-106.
    View in: PubMed
    Score: 0.014
  19. Chen X, Sood S, Yang CS, Li N, Sun Z. Five-lipoxygenase pathway of arachidonic acid metabolism in carcino-genesis and cancer chemoprevention. Curr Cancer Drug Targets. 2006 Nov; 6(7):613-22.
    View in: PubMed
    Score: 0.013
  20. Liu T, Zhang X, So CK, Wang S, Wang P, Yan L, Myers R, Chen Z, Patterson AP, Yang CS, Chen X. Regulation of Cdx2 expression by promoter methylation, and effects of Cdx2 transfection on morphology and gene expression of human esophageal epithelial cells. Carcinogenesis. 2007 Feb; 28(2):488-96.
    View in: PubMed
    Score: 0.013
  21. Zhang X, Feng J, Ye X, Yao Y, Zhou P, Chen X. Development of an immunocytokine, IL-2-183B2scFv, for targeted immunotherapy of ovarian cancer. Gynecol Oncol. 2006 Dec; 103(3):848-52.
    View in: PubMed
    Score: 0.013
  22. Sood S, Shiff SJ, Yang CS, Chen X. Selection of topically applied non-steroidal anti-inflammatory drugs for oral cancer chemoprevention. Oral Oncol. 2005 Jul; 41(6):562-7.
    View in: PubMed
    Score: 0.012
  23. Li N, Sood S, Wang S, Fang M, Wang P, Sun Z, Yang CS, Chen X. Overexpression of 5-lipoxygenase and cyclooxygenase 2 in hamster and human oral cancer and chemopreventive effects of zileuton and celecoxib. Clin Cancer Res. 2005 Mar 01; 11(5):2089-96.
    View in: PubMed
    Score: 0.012
  24. Chen X, Wang S, Wu N, Sood S, Wang P, Jin Z, Beer DG, Giordano TJ, Lin Y, Shih WC, Lubet RA, Yang CS. Overexpression of 5-lipoxygenase in rat and human esophageal adenocarcinoma and inhibitory effects of zileuton and celecoxib on carcinogenesis. Clin Cancer Res. 2004 Oct 01; 10(19):6703-9.
    View in: PubMed
    Score: 0.012
  25. Chen X, Wang S, Wu N, Yang CS. Leukotriene A4 hydrolase as a target for cancer prevention and therapy. Curr Cancer Drug Targets. 2004 May; 4(3):267-83.
    View in: PubMed
    Score: 0.011
  26. Chen X, Li N, Wang S, Wu N, Hong J, Jiao X, Krasna MJ, Beer DG, Yang CS. Leukotriene A4 hydrolase in rat and human esophageal adenocarcinomas and inhibitory effects of bestatin. J Natl Cancer Inst. 2003 Jul 16; 95(14):1053-61.
    View in: PubMed
    Score: 0.011
  27. Chen X, Ding Y, Liu CG, Mikhail S, Yang CS. Overexpression of glucose-regulated protein 94 (Grp94) in esophageal adenocarcinomas of a rat surgical model and humans. Carcinogenesis. 2002 Jan; 23(1):123-30.
    View in: PubMed
    Score: 0.010
  28. Chen X, Yang CS. Esophageal adenocarcinoma: a review and perspectives on the mechanism of carcinogenesis and chemoprevention. Carcinogenesis. 2001 Aug; 22(8):1119-29.
    View in: PubMed
    Score: 0.009
  29. Shi M, Ren S, Chen H, Li J, Huang C, Li Y, Han Y, Li Y, Sun Z, Chen X, Xiong Z. Alcohol drinking inhibits NOTCH-PAX9 signaling in esophageal squamous epithelial cells. J Pathol. 2021 04; 253(4):384-395.
    View in: PubMed
    Score: 0.009
  30. Niture S, Lin M, Odera JO, Moore J, Zhe H, Chen X, Suy S, Collins SP, Kumar D. TNFAIP8 drives metabolic reprogramming to promote prostate cancer cell proliferation. Int J Biochem Cell Biol. 2021 01; 130:105885.
    View in: PubMed
    Score: 0.009
  31. Bowman BM, Montgomery SA, Schrank TP, Simon JM, Ptacek TS, Tamir TY, Mulvaney KM, Weir SJ, Nguyen TT, Murphy RM, Makowski L, Hayes DN, Chen XL, Randell SH, Weissman BE, Major MB. A conditional mouse expressing an activating mutation in NRF2 displays hyperplasia of the upper gastrointestinal tract and decreased white adipose tissue. J Pathol. 2020 10; 252(2):125-137.
    View in: PubMed
    Score: 0.009
  32. Chen X, Ding YW, Yang Gy, Bondoc F, Lee MJ, Yang CS. Oxidative damage in an esophageal adenocarcinoma model with rats. Carcinogenesis. 2000 Feb; 21(2):257-63.
    View in: PubMed
    Score: 0.008
  33. Adekoya TO, Smith N, Aladeniyi T, Blumer JB, Chen XL, Richardson RM. Activator of G protein signaling 3 modulates prostate tumor development and progression. Carcinogenesis. 2019 12 31; 40(12):1504-1513.
    View in: PubMed
    Score: 0.008
  34. Yang W, Liu H, Duan B, Xu X, Carmody D, Luo S, Walsh KM, Abbruzzese JL, Zhang X, Chen X, Wei Q. Three novel genetic variants in NRF2 signaling pathway genes are associated with pancreatic cancer risk. Cancer Sci. 2019 Jun; 110(6):2022-2032.
    View in: PubMed
    Score: 0.008
  35. Jiang M, Li H, Zhang Y, Yang Y, Lu R, Liu K, Lin S, Lan X, Wang H, Wu H, Zhu J, Zhou Z, Xu J, Lee DK, Zhang L, Lee YC, Yuan J, Abrams JA, Wang TC, Sepulveda AR, Wu Q, Chen H, Sun X, She J, Chen X, Que J. Transitional basal cells at the squamous-columnar junction generate Barrett's oesophagus. Nature. 2017 10 26; 550(7677):529-533.
    View in: PubMed
    Score: 0.007
  36. Liu Y, Li Y, Fu Y, Liu T, Liu X, Zhang X, Fu J, Guan X, Chen T, Chen X, Sun Z. Quantitative prediction of oral cancer risk in patients with oral leukoplakia. Oncotarget. 2017 Jul 11; 8(28):46057-46064.
    View in: PubMed
    Score: 0.007
  37. Cuevas-Nunez MC, Gomes CBF, Woo SB, Ramsey MR, Chen XL, Xu S, Xu T, Zhan Q, Murphy GF, Lian CG. Biological significance of 5-hydroxymethylcytosine in oral epithelial dysplasia and oral squamous cell carcinoma. Oral Surg Oral Med Oral Pathol Oral Radiol. 2018 Jan; 125(1):59-73.e2.
    View in: PubMed
    Score: 0.007
  38. Lan A, Li W, Liu Y, Xiong Z, Zhang X, Zhou S, Palko O, Chen H, Kapita M, Prigge JR, Schmidt EE, Chen X, Sun Z, Chen XL. Chemoprevention of oxidative stress-associated oral carcinogenesis by sulforaphane depends on NRF2 and the isothiocyanate moiety. Oncotarget. 2016 Aug 16; 7(33):53502-53514.
    View in: PubMed
    Score: 0.007
  39. Li J, Chen XL, Shaker A, Oshima T, Shan J, Miwa H, Feng C, Zhang J. Contribution of immunomodulators to gastroesophageal reflux disease and its complications: stromal cells, interleukin 4, and adiponectin. Ann N Y Acad Sci. 2016 09; 1380(1):183-194.
    View in: PubMed
    Score: 0.007
  40. Zhu Y, Wang P, Zhao Y, Yang C, Clark A, Leung T, Chen X, Sang S. Synthesis, evaluation, and metabolism of novel [6]-shogaol derivatives as potent Nrf2 activators. Free Radic Biol Med. 2016 06; 95:243-54.
    View in: PubMed
    Score: 0.006
  41. Zhu Y, Fu J, Shurlknight KL, Soroka DN, Hu Y, Chen X, Sang S. Novel Resveratrol-Based Aspirin Prodrugs: Synthesis, Metabolism, and Anticancer Activity. J Med Chem. 2015 Aug 27; 58(16):6494-506.
    View in: PubMed
    Score: 0.006
  42. Liu Y, Li J, Liu X, Liu X, Khawar W, Zhang X, Wang F, Chen X, Sun Z. Quantitative risk stratification of oral leukoplakia with exfoliative cytology. PLoS One. 2015; 10(5):e0126760.
    View in: PubMed
    Score: 0.006
  43. Dellon ES, Speck O, Woodward K, Covey S, Rusin S, Gebhart JH, Chen X, Woosley JT, Shaheen NJ. Markers of eosinophilic inflammation for diagnosis of eosinophilic esophagitis and proton pump inhibitor-responsive esophageal eosinophilia: a prospective study. Clin Gastroenterol Hepatol. 2014 Dec; 12(12):2015-22.
    View in: PubMed
    Score: 0.006
  44. Fang Y, Chen X, Bajpai M, Verma A, Das KM, Souza RF, Garman KS, Donohoe CL, O'Farrell NJ, Reynolds JV, Dvorak K. Cellular origins and molecular mechanisms of Barrett's esophagus and esophageal adenocarcinoma. Ann N Y Acad Sci. 2013 Oct; 1300:187-199.
    View in: PubMed
    Score: 0.005
  45. Liu K, Jiang M, Lu Y, Chen H, Sun J, Wu S, Ku WY, Nakagawa H, Kita Y, Natsugoe S, Peters JH, Rustgi A, Onaitis MW, Kiernan A, Chen X, Que J. Sox2 cooperates with inflammation-mediated Stat3 activation in the malignant transformation of foregut basal progenitor cells. Cell Stem Cell. 2013 Mar 07; 12(3):304-15.
    View in: PubMed
    Score: 0.005
  46. Su Y, Chen X, Klein M, Fang M, Wang S, Yang CS, Goyal RK. Phenotype of columnar-lined esophagus in rats with esophagogastroduodenal anastomosis: similarity to human Barrett's esophagus. Lab Invest. 2004 Jun; 84(6):753-65.
    View in: PubMed
    Score: 0.003
  47. Hong J, Bose M, Ju J, Ryu JH, Chen X, Sang S, Lee MJ, Yang CS. Modulation of arachidonic acid metabolism by curcumin and related beta-diketone derivatives: effects on cytosolic phospholipase A(2), cyclooxygenases and 5-lipoxygenase. Carcinogenesis. 2004 Sep; 25(9):1671-9.
    View in: PubMed
    Score: 0.003
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
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