Xioxin Chen to Animals
This is a "connection" page, showing publications Xioxin Chen has written about Animals.
Connection Strength
1.095
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Odera JO, Xiong Z, Huang C, Gu N, Yang W, Githang'a J, Odera E, Paiboonrungruang C, Chen X. NRF2/ACSS2 axis mediates the metabolic effect of alcohol drinking on esophageal squamous cell carcinoma. Biochem J. 2020 08 28; 477(16):3075-3089.
Score: 0.057
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Fu J, Xiong Z, Huang C, Li J, Yang W, Han Y, Paiboonrungruan C, Major MB, Chen KN, Kang X, Chen X. Hyperactivity of the transcription factor Nrf2 causes metabolic reprogramming in mouse esophagus. J Biol Chem. 2019 01 04; 294(1):327-340.
Score: 0.051
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Ma S, Paiboonrungruan C, Yan T, Williams KP, Major MB, Chen XL. Targeted therapy of esophageal squamous cell carcinoma: the NRF2 signaling pathway as target. Ann N Y Acad Sci. 2018 12; 1434(1):164-172.
Score: 0.049
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Xiong Z, Ren S, Chen H, Liu Y, Huang C, Zhang YL, Odera JO, Chen T, Kist R, Peters H, Garman K, Sun Z, Chen X. PAX9 regulates squamous cell differentiation and carcinogenesis in the oro-oesophageal epithelium. J Pathol. 2018 02; 244(2):164-175.
Score: 0.048
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Fan H, Paiboonrungruan C, Zhang X, Prigge JR, Schmidt EE, Sun Z, Chen X. Nrf2 regulates cellular behaviors and Notch signaling in oral squamous cell carcinoma cells. Biochem Biophys Res Commun. 2017 11 04; 493(1):833-839.
Score: 0.047
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Liu Y, Xiong Z, Beasley A, D'Amico T, Chen XL. Personalized and targeted therapy of esophageal squamous cell carcinoma: an update. Ann N Y Acad Sci. 2016 10; 1381(1):66-73.
Score: 0.043
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Chen H, Beasley A, Hu Y, Chen X. A Zebrafish Model for Studies on Esophageal Epithelial Biology. PLoS One. 2015; 10(12):e0143878.
Score: 0.041
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He J, Fang Y, Chen X. Surgical Models of Gastroesophageal Reflux with Mice. J Vis Exp. 2015 Aug 25; (102):e53012.
Score: 0.041
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Chen H, Hu Y, Fang Y, Djukic Z, Yamamoto M, Shaheen NJ, Orlando RC, Chen X. Nrf2 deficiency impairs the barrier function of mouse oesophageal epithelium. Gut. 2014 May; 63(5):711-9.
Score: 0.035
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Hu B, Chen H, Liu X, Zhang C, Cole GJ, Lee JA, Chen X. Transgenic overexpression of cdx1b induces metaplastic changes of gene expression in zebrafish esophageal squamous epithelium. Zebrafish. 2013 Jun; 10(2):218-27.
Score: 0.035
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Chen X, Zhang X, Lu Y, Shim JY, Sang S, Sun Z, Chen X. Chemoprevention of 7,12-dimethylbenz[a]anthracene (DMBA)-induced hamster cheek pouch carcinogenesis by a 5-lipoxygenase inhibitor, garcinol. Nutr Cancer. 2012; 64(8):1211-1218.
Score: 0.033
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Chen H, Li J, Li H, Hu Y, Tevebaugh W, Yamamoto M, Que J, Chen X. Transcript profiling identifies dynamic gene expression patterns and an important role for Nrf2/Keap1 pathway in the developing mouse esophagus. PLoS One. 2012; 7(5):e36504.
Score: 0.032
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Chen H, Fang Y, Tevebaugh W, Orlando RC, Shaheen NJ, Chen X. Molecular mechanisms of Barrett's esophagus. Dig Dis Sci. 2011 Dec; 56(12):3405-20.
Score: 0.031
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Rishniw M, Rodriguez P, Que J, Burke ZD, Tosh D, Chen H, Chen X. Molecular aspects of esophageal development. Ann N Y Acad Sci. 2011 Sep; 1232:309-15.
Score: 0.031
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Hu B, Zhang C, Baawo K, Qin R, Cole GJ, Lee JA, Chen X. Zebrafish K5 promoter driven GFP expression as a transgenic system for oral research. Oral Oncol. 2010 Jan; 46(1):31-7.
Score: 0.027
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Hao J, Liu B, Yang CS, Chen X. Gastroesophageal reflux leads to esophageal cancer in a surgical model with mice. BMC Gastroenterol. 2009 Jul 23; 9:59.
Score: 0.027
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Chen X, Qin R, Liu B, Ma Y, Su Y, Yang CS, Glickman JN, Odze RD, Shaheen NJ. Multilayered epithelium in a rat model and human Barrett's esophagus: similar expression patterns of transcription factors and differentiation markers. BMC Gastroenterol. 2008 Jan 11; 8:1.
Score: 0.024
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Sun Z, Sood S, Li N, Yang P, Newman RA, Yang CS, Chen X. Chemoprevention of 7,12-dimethylbenz[a]anthracene (DMBA)-induced oral carcinogenesis in hamster cheek pouch by topical application of a dual inhibitor of epidermal growth factor receptor (EGFR) and ErbB2 tyrosine kinases. Oral Oncol. 2008 Jul; 44(7):652-7.
Score: 0.024
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Chen X, Sood S, Yang CS, Li N, Sun Z. Five-lipoxygenase pathway of arachidonic acid metabolism in carcino-genesis and cancer chemoprevention. Curr Cancer Drug Targets. 2006 Nov; 6(7):613-22.
Score: 0.022
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Zhang X, Feng J, Ye X, Yao Y, Zhou P, Chen X. Development of an immunocytokine, IL-2-183B2scFv, for targeted immunotherapy of ovarian cancer. Gynecol Oncol. 2006 Dec; 103(3):848-52.
Score: 0.022
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Sun Z, Sood S, Li N, Ramji D, Yang P, Newman RA, Yang CS, Chen X. Involvement of the 5-lipoxygenase/leukotriene A4 hydrolase pathway in 7,12-dimethylbenz[a]anthracene (DMBA)-induced oral carcinogenesis in hamster cheek pouch, and inhibition of carcinogenesis by its inhibitors. Carcinogenesis. 2006 Sep; 27(9):1902-8.
Score: 0.021
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Sood S, Shiff SJ, Yang CS, Chen X. Selection of topically applied non-steroidal anti-inflammatory drugs for oral cancer chemoprevention. Oral Oncol. 2005 Jul; 41(6):562-7.
Score: 0.020
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Li N, Sood S, Wang S, Fang M, Wang P, Sun Z, Yang CS, Chen X. Overexpression of 5-lipoxygenase and cyclooxygenase 2 in hamster and human oral cancer and chemopreventive effects of zileuton and celecoxib. Clin Cancer Res. 2005 Mar 01; 11(5):2089-96.
Score: 0.020
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Chen X, Wang S, Wu N, Sood S, Wang P, Jin Z, Beer DG, Giordano TJ, Lin Y, Shih WC, Lubet RA, Yang CS. Overexpression of 5-lipoxygenase in rat and human esophageal adenocarcinoma and inhibitory effects of zileuton and celecoxib on carcinogenesis. Clin Cancer Res. 2004 Oct 01; 10(19):6703-9.
Score: 0.019
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Chen X, Wang S, Wu N, Yang CS. Leukotriene A4 hydrolase as a target for cancer prevention and therapy. Curr Cancer Drug Targets. 2004 May; 4(3):267-83.
Score: 0.019
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Chen X, Li N, Wang S, Wu N, Hong J, Jiao X, Krasna MJ, Beer DG, Yang CS. Leukotriene A4 hydrolase in rat and human esophageal adenocarcinomas and inhibitory effects of bestatin. J Natl Cancer Inst. 2003 Jul 16; 95(14):1053-61.
Score: 0.018
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Chen X, Li N, Wang S, Hong J, Fang M, Yousselfson J, Yang P, Newman RA, Lubet RA, Yang CS. Aberrant arachidonic acid metabolism in esophageal adenocarcinogenesis, and the effects of sulindac, nordihydroguaiaretic acid, and alpha-difluoromethylornithine on tumorigenesis in a rat surgical model. Carcinogenesis. 2002 Dec; 23(12):2095-102.
Score: 0.017
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Chen X, Ding Y, Liu CG, Mikhail S, Yang CS. Overexpression of glucose-regulated protein 94 (Grp94) in esophageal adenocarcinomas of a rat surgical model and humans. Carcinogenesis. 2002 Jan; 23(1):123-30.
Score: 0.016
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Chen X, Yang CS. Esophageal adenocarcinoma: a review and perspectives on the mechanism of carcinogenesis and chemoprevention. Carcinogenesis. 2001 Aug; 22(8):1119-29.
Score: 0.015
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Shi M, Ren S, Chen H, Li J, Huang C, Li Y, Han Y, Li Y, Sun Z, Chen X, Xiong Z. Alcohol drinking inhibits NOTCH-PAX9 signaling in esophageal squamous epithelial cells. J Pathol. 2021 04; 253(4):384-395.
Score: 0.015
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Bowman BM, Montgomery SA, Schrank TP, Simon JM, Ptacek TS, Tamir TY, Mulvaney KM, Weir SJ, Nguyen TT, Murphy RM, Makowski L, Hayes DN, Chen XL, Randell SH, Weissman BE, Major MB. A conditional mouse expressing an activating mutation in NRF2 displays hyperplasia of the upper gastrointestinal tract and decreased white adipose tissue. J Pathol. 2020 10; 252(2):125-137.
Score: 0.014
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Chen X, Mikhail SS, Ding YW, Yang Gy, Bondoc F, Yang CS. Effects of vitamin E and selenium supplementation on esophageal adenocarcinogenesis in a surgical model with rats. Carcinogenesis. 2000 Aug; 21(8):1531-6.
Score: 0.014
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Chen X, Ding YW, Yang Gy, Bondoc F, Lee MJ, Yang CS. Oxidative damage in an esophageal adenocarcinoma model with rats. Carcinogenesis. 2000 Feb; 21(2):257-63.
Score: 0.014
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Adekoya TO, Smith N, Aladeniyi T, Blumer JB, Chen XL, Richardson RM. Activator of G protein signaling 3 modulates prostate tumor development and progression. Carcinogenesis. 2019 12 31; 40(12):1504-1513.
Score: 0.014
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Chen X, Yang Gy, Ding WY, Bondoc F, Curtis SK, Yang CS. An esophagogastroduodenal anastomosis model for esophageal adenocarcinogenesis in rats and enhancement by iron overload. Carcinogenesis. 1999 Sep; 20(9):1801-8.
Score: 0.013
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Jiang M, Li H, Zhang Y, Yang Y, Lu R, Liu K, Lin S, Lan X, Wang H, Wu H, Zhu J, Zhou Z, Xu J, Lee DK, Zhang L, Lee YC, Yuan J, Abrams JA, Wang TC, Sepulveda AR, Wu Q, Chen H, Sun X, She J, Chen X, Que J. Transitional basal cells at the squamous-columnar junction generate Barrett's oesophagus. Nature. 2017 10 26; 550(7677):529-533.
Score: 0.012
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Cuevas-Nunez MC, Gomes CBF, Woo SB, Ramsey MR, Chen XL, Xu S, Xu T, Zhan Q, Murphy GF, Lian CG. Biological significance of 5-hydroxymethylcytosine in oral epithelial dysplasia and oral squamous cell carcinoma. Oral Surg Oral Med Oral Pathol Oral Radiol. 2018 Jan; 125(1):59-73.e2.
Score: 0.012
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Lan A, Li W, Liu Y, Xiong Z, Zhang X, Zhou S, Palko O, Chen H, Kapita M, Prigge JR, Schmidt EE, Chen X, Sun Z, Chen XL. Chemoprevention of oxidative stress-associated oral carcinogenesis by sulforaphane depends on NRF2 and the isothiocyanate moiety. Oncotarget. 2016 Aug 16; 7(33):53502-53514.
Score: 0.011
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Zhu Y, Wang P, Zhao Y, Yang C, Clark A, Leung T, Chen X, Sang S. Synthesis, evaluation, and metabolism of novel [6]-shogaol derivatives as potent Nrf2 activators. Free Radic Biol Med. 2016 06; 95:243-54.
Score: 0.011
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Zhu Y, Fu J, Shurlknight KL, Soroka DN, Hu Y, Chen X, Sang S. Novel Resveratrol-Based Aspirin Prodrugs: Synthesis, Metabolism, and Anticancer Activity. J Med Chem. 2015 Aug 27; 58(16):6494-506.
Score: 0.010
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Fang Y, Chen X, Bajpai M, Verma A, Das KM, Souza RF, Garman KS, Donohoe CL, O'Farrell NJ, Reynolds JV, Dvorak K. Cellular origins and molecular mechanisms of Barrett's esophagus and esophageal adenocarcinoma. Ann N Y Acad Sci. 2013 Oct; 1300:187-199.
Score: 0.009
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Raghuwanshi SK, Smith N, Rivers EJ, Thomas AJ, Sutton N, Hu Y, Mukhopadhyay S, Chen XL, Leung T, Richardson RM. G protein-coupled receptor kinase 6 deficiency promotes angiogenesis, tumor progression, and metastasis. J Immunol. 2013 May 15; 190(10):5329-36.
Score: 0.009
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Liu K, Jiang M, Lu Y, Chen H, Sun J, Wu S, Ku WY, Nakagawa H, Kita Y, Natsugoe S, Peters JH, Rustgi A, Onaitis MW, Kiernan A, Chen X, Que J. Sox2 cooperates with inflammation-mediated Stat3 activation in the malignant transformation of foregut basal progenitor cells. Cell Stem Cell. 2013 Mar 07; 12(3):304-15.
Score: 0.009
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Yang H, Jia X, Chen X, Yang CS, Li N. Time-selective chemoprevention of vitamin E and selenium on esophageal carcinogenesis in rats: the possible role of nuclear factor kappaB signaling pathway. Int J Cancer. 2012 Oct 01; 131(7):1517-27.
Score: 0.008
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Yang H, Fang J, Jia X, Han C, Chen X, Yang CS, Li N. Chemopreventive effects of early-stage and late-stage supplementation of vitamin E and selenium on esophageal carcinogenesis in rats maintained on a low vitamin E/selenium diet. Carcinogenesis. 2011 Mar; 32(3):381-8.
Score: 0.007
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Hao J, Zhang B, Liu B, Lee M, Hao X, Reuhl KR, Chen X, Yang CS. Effect of alpha-tocopherol, N-acetylcysteine and omeprazole on esophageal adenocarcinoma formation in a rat surgical model. Int J Cancer. 2009 Mar 15; 124(6):1270-5.
Score: 0.006
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Raghuwanshi SK, Nasser MW, Chen X, Strieter RM, Richardson RM. Depletion of beta-arrestin-2 promotes tumor growth and angiogenesis in a murine model of lung cancer. J Immunol. 2008 Apr 15; 180(8):5699-706.
Score: 0.006
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Su Y, Chen X, Klein M, Fang M, Wang S, Yang CS, Goyal RK. Phenotype of columnar-lined esophagus in rats with esophagogastroduodenal anastomosis: similarity to human Barrett's esophagus. Lab Invest. 2004 Jun; 84(6):753-65.
Score: 0.005
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Hong J, Bose M, Ju J, Ryu JH, Chen X, Sang S, Lee MJ, Yang CS. Modulation of arachidonic acid metabolism by curcumin and related beta-diketone derivatives: effects on cytosolic phospholipase A(2), cyclooxygenases and 5-lipoxygenase. Carcinogenesis. 2004 Sep; 25(9):1671-9.
Score: 0.005
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Li N, Chen X, Liao J, Yang G, Wang S, Josephson Y, Han C, Chen J, Huang MT, Yang CS. Inhibition of 7,12-dimethylbenz[a]anthracene (DMBA)-induced oral carcinogenesis in hamsters by tea and curcumin. Carcinogenesis. 2002 Aug; 23(8):1307-13.
Score: 0.004
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Goldstein SR, Yang GY, Chen X, Curtis SK, Yang CS. Studies of iron deposits, inducible nitric oxide synthase and nitrotyrosine in a rat model for esophageal adenocarcinoma. Carcinogenesis. 1998 Aug; 19(8):1445-9.
Score: 0.003
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Yang G, Wang ZY, Kim S, Liao J, Seril DN, Chen X, Smith TJ, Yang CS. Characterization of early pulmonary hyperproliferation and tumor progression and their inhibition by black tea in a 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced lung tumorigenesis model with A/J mice. Cancer Res. 1997 May 15; 57(10):1889-94.
Score: 0.003