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Gautam Chaudhuri

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InstitutionMeharry Medical College
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    R01HL040872     (CHAUDHURI, GAUTAM)Aug 1, 1989 - Mar 31, 1993
    NIH/NHLBI
    EDRF AND PROSTACYCLIN IN HUMAN UMBILICAL VESSELS
    Role: Principal Investigator

    R01HD031467     (CHAUDHURI, GAUTAM)Aug 1, 1989 - Jul 31, 1999
    NIH/NICHD
    EDRF AND PROSTACYCLIN IN HUMAN UMBILICAL VESSELS
    Role: Principal Investigator

    R01HL046843     (CHAUDHURI, GAUTAM)Aug 1, 1991 - Mar 31, 2001
    NIH/NHLBI
    EDNO AND UTERINE BLOOD FLOW IN PREGNANCY
    Role: Principal Investigator

    R01AI042327     (CHAUDHURI, GAUTAM)Dec 15, 1997 - Nov 30, 2001
    NIH/NIAID
    DNA ANTISENSE APPROACH AGAINST LEISHMANIASIS
    Role: Principal Investigator

    R01HD035991     (CHAUDHURI, GAUTAM)Feb 1, 1998 - Jan 31, 2005
    NIH/NICHD
    PREGNANCY AND GI MOTILITY: ROLE OF NITRIC OXIDE
    Role: Principal Investigator

    K12HD001281     (CHAUDHURI, GAUTAM)Sep 30, 1998 - Nov 30, 2003
    NIH/NICHD
    UCLA Women's Reproductive Health Research Center
    Role: Principal Investigator

    R01CA078357     (CHAUDHURI, GAUTAM)Jul 1, 2000 - Jun 30, 2006
    NIH/NCI
    ESTRADIOL, NITRIC OXIDE AND CYCLIN D1 IN BREAST CANCER
    Role: Principal Investigator

    K12HD001400     (CHAUDHURI, GAUTAM)Aug 30, 2000 - Jul 31, 2012
    NIH/NICHD
    Building Interdisciplinary Research Careers in Women's Health (BIRCWH) Center
    Role: Principal Investigator

    R01AG015857     (CHAUDHURI, GAUTAM)Sep 30, 2000 - Aug 31, 2006
    NIH/NIA
    ROLE OF NO AND ESTRADIOL IN AGING AND ATHEROGENESIS
    Role: Principal Investigator

    R01HL083038     (CHAUDHURI, GAUTAM)Aug 1, 2006 - Jul 31, 2011
    NIH/NHLBI
    Pregnancy, Pre-eclampsia, Anti-oxidants and Endothelial Cell Function
    Role: Principal Investigator

    R21AI076757     (CHAUDHURI, GAUTAM)Jun 1, 2008 - Oct 31, 2010
    NIH/NIAID
    SRP RNA level as a determinant of leishmanial parasitism of macrophages
    Role: Principal Investigator

    R21CA181920     (CHAUDHURI, GAUTAM)Aug 5, 2014 - Jul 31, 2016
    NIH/NCI
    Manipulation of macrophage Alu RNA metabolism by breast cancer cells
    Role: Principal Investigator

    R01HL135606     (CHAUDHURI, GAUTAM)Jul 1, 2017 - Jun 30, 2021
    NIH/NHLBI
    Gamma-Aminobutyric Acid is Synthesized by Endothelial Cells: Implications in Preeclampsia
    Role: Principal Investigator

    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Ellison M, Mittal M, Chaudhuri M, Chaudhuri G, Misra S. The role of the redox/miR-6855-3p/PRDX5A axis in reversing SLUG-mediated BRCA2 silencing in breast cancer cells. Cell Commun Signal. 2020 Jan 27; 18(1):15. PMID: 31987042.
      Citations:    Fields:    
    2. Kawahara B, Ramadoss S, Chaudhuri G, Janzen C, Sen S, Mascharak PK. Carbon monoxide sensitizes cisplatin-resistant ovarian cancer cell lines toward cisplatin via attenuation of levels of glutathione and nuclear metallothionein. J Inorg Biochem. 2019 02; 191:29-39. PMID: 30458366.
      Citations: 7     Fields:    Translation:HumansCells
    3. Janzen C, Sen S, Lei MY, Gagliardi de Assumpcao M, Challis J, Chaudhuri G. The Role of Epithelial to Mesenchymal Transition in Human Amniotic Membrane Rupture. J Clin Endocrinol Metab. 2017 04 01; 102(4):1261-1269. PMID: 28388726.
      Citations: 5     Fields:    Translation:Humans
    4. Ramadoss S, Sen S, Ramachandran I, Roy S, Chaudhuri G, Farias-Eisner R. Lysine-specific demethylase KDM3A regulates ovarian cancer stemness and chemoresistance. Oncogene. 2017 03; 36(11):1537-1545. PMID: 27694900.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    5. Martinez L, Thames E, Kim J, Chaudhuri G, Singh R, Pervin S. Increased sensitivity of African American triple negative breast cancer cells to nitric oxide-induced mitochondria-mediated apoptosis. BMC Cancer. 2016 07 29; 16:559. PMID: 27473585.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    6. Sen S, Roy S, Bandyopadhyay G, Scott B, Xiao D, Ramadoss S, Mahata SK, Chaudhuri G. ?-Aminobutyric Acid Is Synthesized and Released by the Endothelium: Potential Implications. Circ Res. 2016 Aug 19; 119(5):621-34. PMID: 27354210.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    7. Sen S, Kawahara B, Mahata SK, Tsai R, Yoon A, Hwang L, Hu-Moore K, Villanueva C, Vajihuddin A, Parameshwar P, You M, Bhaskar DL, Gomez O, Faull KF, Farias-Eisner R, Chaudhuri G. Cystathionine: A novel oncometabolite in human breast cancer. Arch Biochem Biophys. 2016 08 15; 604:95-102. PMID: 27311614.
      Citations: 5     Fields:    Translation:HumansCells
    8. Sen S, Kawahara B, Gupta D, Tsai R, Khachatryan M, Roy-Chowdhuri S, Bose S, Yoon A, Faull K, Farias-Eisner R, Chaudhuri G. Role of cystathionine ß-synthase in human breast Cancer. Free Radic Biol Med. 2015 Sep; 86:228-38. PMID: 26051168.
      Citations: 27     Fields:    Translation:HumansAnimalsCells
    9. Dhar G, Sen S, Chaudhuri G. Acid gradient across plasma membrane can drive phosphate bond synthesis in cancer cells: acidic tumor milieu as a potential energy source. PLoS One. 2015; 10(4):e0124070. PMID: 25874623.
      Citations: 1     Fields:    Translation:HumansCells
    10. Rao R, Sen S, Han B, Ramadoss S, Chaudhuri G. Gestational diabetes, preeclampsia and cytokine release: similarities and differences in endothelial cell function. Adv Exp Med Biol. 2014; 814:69-75. PMID: 25015801.
      Citations: 3     Fields:    Translation:Humans
    11. Singh R, Avliyakulov NK, Braga M, Haykinson MJ, Martinez L, Singh V, Parveen M, Chaudhuri G, Pervin S. Proteomic identification of mitochondrial targets of arginase in human breast cancer. PLoS One. 2013; 8(11):e79242. PMID: 24223914.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    12. Sen S, Kawahara B, Fry NL, Farias-Eisner R, Zhang D, Mascharak PK, Chaudhuri G. A light-activated NO donor attenuates anchorage independent growth of cancer cells: Important role of a cross talk between NO and other reactive oxygen species. Arch Biochem Biophys. 2013 Dec; 540(1-2):33-40. PMID: 24157690.
      Citations: 2     Fields:    Translation:HumansCells
    13. Sen S, Rao R, Chaudhuri G. Endothelial cell function in utero-placental circulation physiology and pathophysiology. Curr Vasc Pharmacol. 2013 Sep; 11(5):730-6. PMID: 24063384.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    14. Sen S, Kawahara B, Fukuto J, Chaudhuri G. Induction of a feed forward pro-apoptotic mechanistic loop by nitric oxide in a human breast cancer model. PLoS One. 2013; 8(8):e70593. PMID: 23950968.
      Citations: 1     Fields:    Translation:HumansCells
    15. Pervin S, Tran L, Urman R, Braga M, Parveen M, Li SA, Chaudhuri G, Singh R. Oxidative stress specifically downregulates survivin to promote breast tumour formation. Br J Cancer. 2013 Mar 05; 108(4):848-58. PMID: 23403820.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    16. Pervin S, Hewison M, Braga M, Tran L, Chun R, Karam A, Chaudhuri G, Norris K, Singh R. Down-regulation of vitamin D receptor in mammospheres: implications for vitamin D resistance in breast cancer and potential for combination therapy. PLoS One. 2013; 8(1):e53287. PMID: 23341935.
      Citations: 19     Fields:    Translation:HumansAnimalsCells
    17. Sen S, Kawahara B, Chaudhuri G. Mitochondrial-associated nitric oxide synthase activity inhibits cytochrome c oxidase: implications for breast cancer. Free Radic Biol Med. 2013 Apr; 57:210-20. PMID: 23089229.
      Citations: 12     Fields:    Translation:HumansCells
    18. Sen S, Kawahara B, Chaudhuri G. Maintenance of higher H2O2 levels, and its mechanism of action to induce growth in breast cancer cells: important roles of bioactive catalase and PP2A. Free Radic Biol Med. 2012 Oct 15; 53(8):1541-51. PMID: 22749807.
      Citations: 10     Fields:    Translation:HumansCells
    19. Tarallo V, Hirano Y, Gelfand BD, Dridi S, Kerur N, Kim Y, Cho WG, Kaneko H, Fowler BJ, Bogdanovich S, Albuquerque RJ, Hauswirth WW, Chiodo VA, Kugel JF, Goodrich JA, Ponicsan SL, Chaudhuri G, Murphy MP, Dunaief JL, Ambati BK, Ogura Y, Yoo JW, Lee DK, Provost P, Hinton DR, Núñez G, Baffi JZ, Kleinman ME, Ambati J. DICER1 loss and Alu RNA induce age-related macular degeneration via the NLRP3 inflammasome and MyD88. Cell. 2012 May 11; 149(4):847-59. PMID: 22541070.
      Citations: 203     Fields:    Translation:HumansAnimalsCells
    20. Bailey CK, Mittal MK, Misra S, Chaudhuri G. High motility of triple-negative breast cancer cells is due to repression of plakoglobin gene by metastasis modulator protein SLUG. J Biol Chem. 2012 Jun 01; 287(23):19472-86. PMID: 22496452.
      Citations: 14     Fields:    Translation:HumansCells
    21. Janzen C, Sen S, Cuevas J, Reddy ST, Chaudhuri G. Protein phosphatase 2A promotes endothelial survival via stabilization of translational inhibitor 4E-BP1 following exposure to tumor necrosis factor-a. Arterioscler Thromb Vasc Biol. 2011 Nov; 31(11):2586-94. PMID: 21903942.
      Citations: 4     Fields:    Translation:HumansCells
    22. Kaneko H, Dridi S, Tarallo V, Gelfand BD, Fowler BJ, Cho WG, Kleinman ME, Ponicsan SL, Hauswirth WW, Chiodo VA, Karikó K, Yoo JW, Lee DK, Hadziahmetovic M, Song Y, Misra S, Chaudhuri G, Buaas FW, Braun RE, Hinton DR, Zhang Q, Grossniklaus HE, Provis JM, Madigan MC, Milam AH, Justice NL, Albuquerque RJ, Blandford AD, Bogdanovich S, Hirano Y, Witta J, Fuchs E, Littman DR, Ambati BK, Rudin CM, Chong MM, Provost P, Kugel JF, Goodrich JA, Dunaief JL, Baffi JZ, Ambati J. DICER1 deficit induces Alu RNA toxicity in age-related macular degeneration. Nature. 2011 Mar 17; 471(7338):325-30. PMID: 21297615.
      Citations: 242     Fields:    Translation:HumansAnimalsCells
    23. Hall M, Misra S, Chaudhuri M, Chaudhuri G. Peptide aptamer mimicking RAD51-binding domain of BRCA2 inhibits DNA damage repair and survival in Trypanosoma brucei. Microb Pathog. 2011 May; 50(5):252-62. PMID: 21296653.
      Citations: 3     Fields:    Translation:AnimalsCells
    24. Farrow AL, Rana T, Mittal MK, Misra S, Chaudhuri G. Leishmania-induced repression of selected non-coding RNA genes containing B-box element at their promoters in alternatively polarized M2 macrophages. Mol Cell Biochem. 2011 Apr; 350(1-2):47-57. PMID: 21165676.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    25. Rana T, Misra S, Mittal MK, Farrow AL, Wilson KT, Linton MF, Fazio S, Willis IM, Chaudhuri G. Mechanism of down-regulation of RNA polymerase III-transcribed non-coding RNA genes in macrophages by Leishmania. J Biol Chem. 2011 Feb 25; 286(8):6614-26. PMID: 21149457.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    26. Fung C, Evans E, Shin D, Shin BC, Zhao Y, Sankar R, Chaudhuri G, Devaskar SU. Hypoxic-ischemic brain injury exacerbates neuronal apoptosis and precipitates spontaneous seizures in glucose transporter isoform 3 heterozygous null mice. J Neurosci Res. 2010 Nov 15; 88(15):3386-98. PMID: 20857507.
      Citations: 7     Fields:    Translation:AnimalsCells
    27. Mittal MK, Singh K, Misra S, Chaudhuri G. SLUG-induced elevation of D1 cyclin in breast cancer cells through the inhibition of its ubiquitination. J Biol Chem. 2011 Jan 07; 286(1):469-79. PMID: 21044962.
      Citations: 20     Fields:    Translation:HumansCells
    28. Misra S, Sharma S, Agarwal A, Khedkar SV, Tripathi MK, Mittal MK, Chaudhuri G. Cell cycle-dependent regulation of the bi-directional overlapping promoter of human BRCA2/ZAR2 genes in breast cancer cells. Mol Cancer. 2010 Mar 04; 9:50. PMID: 20202217.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    29. Ochieng J, Chaudhuri G. Cystatin superfamily. J Health Care Poor Underserved. 2010 Feb; 21(1 Suppl):51-70. PMID: 20173285.
      Citations: 26     Fields:    Translation:Humans
    30. Pervin S, Chaudhuri G, Singh R. NO to breast: when, why and why not? Curr Pharm Des. 2010; 16(4):451-62. PMID: 20236074.
      Citations: 6     Fields:    Translation:HumansAnimals
    31. Mittal MK, Myers JN, Bailey CK, Misra S, Chaudhuri G. Mode of action of the retrogene product SNAI1P, a SNAIL homolog, in human breast cancer cells. Mol Biol Rep. 2010 Mar; 37(3):1221-7. PMID: 19277896.
      Citations: 6     Fields:    Translation:HumansCells
    32. van Nas A, Guhathakurta D, Wang SS, Yehya N, Horvath S, Zhang B, Ingram-Drake L, Chaudhuri G, Schadt EE, Drake TA, Arnold AP, Lusis AJ. Elucidating the role of gonadal hormones in sexually dimorphic gene coexpression networks. Endocrinology. 2009 Mar; 150(3):1235-49. PMID: 18974276.
      Citations: 91     Fields:    Translation:Animals
    33. Souter I, Huang A, Martinez-Maza O, Breen EC, Decherney AH, Chaudhuri G, Nathan L. Serum levels of soluble vascular cell adhesion molecule-1, tumor necrosis factor-alpha, and interleukin-6 in in vitro fertilization cycles. Fertil Steril. 2009 May; 91(5 Suppl):2012-9. PMID: 18778820.
      Citations: 5     Fields:    Translation:Humans
    34. Pervin S, Tran AH, Zekavati S, Fukuto JM, Singh R, Chaudhuri G. Increased susceptibility of breast cancer cells to stress mediated inhibition of protein synthesis. Cancer Res. 2008 Jun 15; 68(12):4862-74. PMID: 18559534.
      Citations: 8     Fields:    Translation:HumansCells
    35. Mittal MK, Myers JN, Misra S, Bailey CK, Chaudhuri G. In vivo binding to and functional repression of the VDR gene promoter by SLUG in human breast cells. Biochem Biophys Res Commun. 2008 Jul 18; 372(1):30-4. PMID: 18485278.
      Citations: 23     Fields:    Translation:HumansCells
    36. Pervin S, Singh R, Chaudhuri G. Nitric oxide, N omega-hydroxy-L-arginine and breast cancer. Nitric Oxide. 2008 Sep; 19(2):103-6. PMID: 18474257.
      Citations: 9     Fields:    Translation:Humans
    37. Chaudhuri G. Nuclear receptors and female reproduction: a tale of 3 scientists, Jensen, Gustafsson, and O'Malley. Reprod Sci. 2008 Feb; 15(2):110-20. PMID: 18276948.
      Citations: 1     Fields:    Translation:Humans
    38. Friedlander AH, Chaudhuri G, Altman L. A past medical history of gestational diabetes: its medical significance and its dental implications. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2007 Feb; 103(2):157-63. PMID: 17234528.
      Citations: 1     Fields:    Translation:Humans
    39. Pervin S, Singh R, Hernandez E, Wu G, Chaudhuri G. Nitric oxide in physiologic concentrations targets the translational machinery to increase the proliferation of human breast cancer cells: involvement of mammalian target of rapamycin/eIF4E pathway. Cancer Res. 2007 Jan 01; 67(1):289-99. PMID: 17210710.
      Citations: 34     Fields:    Translation:HumansCells
    40. Porter-Kelley J, Seay M, Singh PK, Chaudhuri G. Bio-available Zn2+ in the growth medium as a cue for Leishmania to express its protective surface protease. Ann Trop Med Parasitol. 2007 Jan; 101(1):89-93. PMID: 17244414.
      Citations:    Fields:    Translation:AnimalsCells
    41. Bailey CK, Misra S, Mittal MK, Chaudhuri G. Human SLUG does not directly bind to CtBP1. Biochem Biophys Res Commun. 2007 Feb 16; 353(3):661-4. PMID: 17194444.
      Citations: 6     Fields:    Translation:HumansCells
    42. Hayashi T, Esaki T, Sumi D, Mukherjee T, Iguchi A, Chaudhuri G. Modulating role of estradiol on arginase II expression in hyperlipidemic rabbits as an atheroprotective mechanism. Proc Natl Acad Sci U S A. 2006 Jul 05; 103(27):10485-10490. PMID: 16801563.
      Citations: 12     Fields:    Translation:AnimalsCells
    43. Misra S, Hall M, Chaudhuri G. Molecular characterization of a human BRCA2 homolog in Leishmania donovani. J Parasitol. 2005 Dec; 91(6):1492-5. PMID: 16539040.
      Citations: 2     Fields:    Translation:AnimalsCells
    44. Misra S, Bennett J, Friew YN, Abdulghani J, Irvin-Wilson CV, Tripathi MK, Williams S, Chaudhuri M, Chaudhuri G. A type II ribonuclease H from Leishmania mitochondria: an enzyme essential for the growth of the parasite. Mol Biochem Parasitol. 2005 Oct; 143(2):135-45. PMID: 15978682.
      Citations: 1     Fields:    Translation:AnimalsCells
    45. Misra S, Tripathi MK, Chaudhuri G. Down-regulation of 7SL RNA expression and impairment of vesicular protein transport pathways by Leishmania infection of macrophages. J Biol Chem. 2005 Aug 12; 280(32):29364-73. PMID: 15955815.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    46. Irvin-Wilson CV, Chaudhuri G. Alternative initiation and splicing in dicer gene expression in human breast cells. Breast Cancer Res. 2005; 7(4):R563-9. PMID: 15987463.
      Citations: 19     Fields:    Translation:HumansCells
    47. Souter I, Janzen C, Martinez-Maza O, Breen EC, Stanczyk F, Chaudhuri G, Nathan L. Serum levels of soluble vascular cell adhesion molecule-1 are decreased in women receiving oral contraceptives compared with normally menstruating women: implications in atherosclerosis. Fertil Steril. 2005 May; 83(5):1480-8. PMID: 15866588.
      Citations: 4     Fields:    Translation:Humans
    48. Tripathi MK, Misra S, Chaudhuri G. Negative regulation of the expressions of cytokeratins 8 and 19 by SLUG repressor protein in human breast cells. Biochem Biophys Res Commun. 2005 Apr 08; 329(2):508-15. PMID: 15737616.
      Citations: 19     Fields:    Translation:HumansCells
    49. Tripathi MK, Chaudhuri G. Down-regulation of UCRP and UBE2L6 in BRCA2 knocked-down human breast cells. Biochem Biophys Res Commun. 2005 Mar 04; 328(1):43-8. PMID: 15670748.
      Citations: 8     Fields:    Translation:HumansCells
    50. Tripathi MK, Misra S, Khedkar SV, Hamilton N, Irvin-Wilson C, Sharan C, Sealy L, Chaudhuri G. Regulation of BRCA2 gene expression by the SLUG repressor protein in human breast cells. J Biol Chem. 2005 Apr 29; 280(17):17163-71. PMID: 15734731.
      Citations: 37     Fields:    Translation:HumansCells
    51. López-Jaramillo P, Díaz LA, Pardo A, Parra G, Jaimes H, Chaudhuri G. Estrogen therapy increases plasma concentrations of nitric oxide metabolites in postmenopausal women but increases flow-mediated vasodilation only in younger women. Fertil Steril. 2004 Dec; 82(6):1550-5. PMID: 15589858.
      Citations: 2     Fields:    Translation:HumansCTClinical Trials
    52. Pervin S, Singh R, Freije WA, Chaudhuri G. MKP-1-induced dephosphorylation of extracellular signal-regulated kinase is essential for triggering nitric oxide-induced apoptosis in human breast cancer cell lines: implications in breast cancer. Cancer Res. 2003 Dec 15; 63(24):8853-60. PMID: 14695202.
      Citations: 24     Fields:    Translation:HumansCells
    53. Han TH, Qamirani E, Nelson AG, Hyduke DR, Chaudhuri G, Kuo L, Liao JC. Regulation of nitric oxide consumption by hypoxic red blood cells. Proc Natl Acad Sci U S A. 2003 Oct 14; 100(21):12504-9. PMID: 14523233.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    54. Pervin S, Singh R, Chaudhuri G. Nitric-oxide-induced Bax integration into the mitochondrial membrane commits MDA-MB-468 cells to apoptosis: essential role of Akt. Cancer Res. 2003 Sep 01; 63(17):5470-9. PMID: 14500383.
      Citations: 17     Fields:    Translation:HumansCells
    55. Berman JR, Almeida FG, Jolin J, Raz S, Chaudhuri G, Gonzalez-Cadavid NF. Correlation of androgen receptors, aromatase, and 5-alpha reductase in the human vagina with menopausal status. Fertil Steril. 2003 Apr; 79(4):925-31. PMID: 12749432.
      Citations: 5     Fields:    Translation:Humans
    56. Mukherjee TK, Nathan L, Dinh H, Reddy ST, Chaudhuri G. 17-epiestriol, an estrogen metabolite, is more potent than estradiol in inhibiting vascular cell adhesion molecule 1 (VCAM-1) mRNA expression. J Biol Chem. 2003 Apr 04; 278(14):11746-52. PMID: 12547825.
      Citations: 12     Fields:    Translation:HumansCells
    57. Reid EA, Cao Z, Wang Y, Leite Browning ML, Newkirk RF, Chaudhuri G, Townsel JG. Molecular cloning and identification of a putative PKC epsilon cDNA from Limulus polyphemus brain. Life Sci. 2003 Jan 10; 72(8):961-76. PMID: 12493576.
      Citations:    Fields:    Translation:AnimalsCells
    58. Singh R, Pervin S, Chaudhuri G. Caspase-8-mediated BID cleavage and release of mitochondrial cytochrome c during Nomega-hydroxy-L-arginine-induced apoptosis in MDA-MB-468 cells. Antagonistic effects of L-ornithine. J Biol Chem. 2002 Oct 04; 277(40):37630-6. PMID: 12145284.
      Citations: 12     Fields:    Translation:HumansCells
    59. Mukherjee TK, Dinh H, Chaudhuri G, Nathan L. Testosterone attenuates expression of vascular cell adhesion molecule-1 by conversion to estradiol by aromatase in endothelial cells: implications in atherosclerosis. Proc Natl Acad Sci U S A. 2002 Mar 19; 99(6):4055-60. PMID: 11904449.
      Citations: 25     Fields:    Translation:HumansAnimals
    60. Campisi R, Nathan L, Pampaloni MH, Schöder H, Sayre JW, Chaudhuri G, Schelbert HR. Noninvasive assessment of coronary microcirculatory function in postmenopausal women and effects of short-term and long-term estrogen administration. Circulation. 2002 Jan 29; 105(4):425-30. PMID: 11815423.
      Citations: 21     Fields:    Translation:HumansCTClinical Trials
    61. Singh R, Pervin S, Wu G, Chaudhuri G. Activation of caspase-3 activity and apoptosis in MDA-MB-468 cells by N(omega)-hydroxy-L-arginine, an inhibitor of arginase, is not solely dependent on reduction in intracellular polyamines. Carcinogenesis. 2001 Nov; 22(11):1863-9. PMID: 11698350.
      Citations: 7     Fields:    Translation:HumansCells
    62. Mishra M, Porter-Kelley JM, Singh PK, Bennett JR, Chaudhuri G. Enhanced activity of antisense phosphorothioate oligos against leishmania amastigotes: augmented uptake of oligo, ribonuclease H activation, and efficient target intervention under altered growth conditions. Biochem Pharmacol. 2001 Sep 01; 62(5):569-80. PMID: 11585054.
      Citations: 5     Fields:    Translation:AnimalsCells
    63. Pervin S, Singh R, Gau CL, Edamatsu H, Tamanoi F, Chaudhuri G. Potentiation of nitric oxide-induced apoptosis of MDA-MB-468 cells by farnesyltransferase inhibitor: implications in breast cancer. Cancer Res. 2001 Jun 15; 61(12):4701-6. PMID: 11406540.
      Citations: 12     Fields:    Translation:HumansCells
    64. Shah S, Nathan L, Singh R, Fu YS, Chaudhuri G. E2 and not P4 increases NO release from NANC nerves of the gastrointestinal tract: implications in pregnancy. Am J Physiol Regul Integr Comp Physiol. 2001 May; 280(5):R1546-54. PMID: 11294780.
      Citations: 23     Fields:    Translation:HumansAnimals
    65. Pervin S, Singh R, Chaudhuri G. Nitric oxide-induced cytostasis and cell cycle arrest of a human breast cancer cell line (MDA-MB-231): potential role of cyclin D1. Proc Natl Acad Sci U S A. 2001 Mar 13; 98(6):3583-8. PMID: 11248121.
      Citations: 33     Fields:    Translation:HumansCells
    66. Nathan L, Shi W, Dinh H, Mukherjee TK, Wang X, Lusis AJ, Chaudhuri G. Testosterone inhibits early atherogenesis by conversion to estradiol: critical role of aromatase. Proc Natl Acad Sci U S A. 2001 Mar 13; 98(6):3589-93. PMID: 11248122.
      Citations: 42     Fields:    Translation:Animals
    67. Mishra M, Bennett JR, Chaudhuri G. Increased efficacy of antileishmanial antisense phosphorothioate oligonucleotides in Leishmania amazonensis overexpressing ribonuclease H. Biochem Pharmacol. 2001 Feb 15; 61(4):467-76. PMID: 11226381.
      Citations: 3     Fields:    Translation:AnimalsCells
    68. Shah S, Hobbs A, Singh R, Cuevas J, Ignarro LJ, Chaudhuri G. Gastrointestinal motility during pregnancy: role of nitrergic component of NANC nerves. Am J Physiol Regul Integr Comp Physiol. 2000 Oct; 279(4):R1478-85. PMID: 11004018.
      Citations: 9     Fields:    Translation:Animals
    69. Ueda Y, Chaudhuri G. Differential expression of B1-containing transcripts in Leishmania-exposed macrophages. J Biol Chem. 2000 Jun 23; 275(25):19428-32. PMID: 10781585.
      Citations: 3     Fields:    Translation:AnimalsCells
    70. Singh R, Pervin S, Karimi A, Cederbaum S, Chaudhuri G. Arginase activity in human breast cancer cell lines: N(omega)-hydroxy-L-arginine selectively inhibits cell proliferation and induces apoptosis in MDA-MB-468 cells. Cancer Res. 2000 Jun 15; 60(12):3305-12. PMID: 10866325.
      Citations: 46     Fields:    Translation:HumansCells
    71. Singh R, Pervin S, Shryne J, Gorski R, Chaudhuri G. Castration increases and androgens decrease nitric oxide synthase activity in the brain: physiologic implications. Proc Natl Acad Sci U S A. 2000 Mar 28; 97(7):3672-7. PMID: 10725371.
      Citations: 10     Fields:    Translation:Animals
    72. Biswas NM, Chaudhuri GR, Sarkar M, Sengupta R. Influence of adrenal cortex on testicular activity in the toad during the breeding season. Life Sci. 2000 Feb 18; 66(13):1253-60. PMID: 10737420.
      Citations: 2     Fields:    Translation:Animals
    73. Honold J, Pusser NL, Nathan L, Chaudhuri G, Ignarro LJ, Sherman MP. Production and excretion of nitrate by human newborn infants: neonates are not little adults. Nitric Oxide. 2000 Feb; 4(1):35-46. PMID: 10733871.
      Citations: 3     Fields:    Translation:Humans
    74. Sharan C, Hamilton NM, Parl AK, Singh PK, Chaudhuri G. Identification and characterization of a transcriptional silencer upstream of the human BRCA2 gene. Biochem Biophys Res Commun. 1999 Nov 19; 265(2):285-90. PMID: 10558858.
      Citations: 10     Fields:    Translation:HumansCells
    75. Hyun J, Chaudhuri G, Fukuto JM. The reductive metabolism of nitric oxide in hepatocytes: possible interaction with thiols. Drug Metab Dispos. 1999 Sep; 27(9):1005-9. PMID: 10460799.
      Citations:    Fields:    Translation:AnimalsCells
    76. Nathan L, Pervin S, Singh R, Rosenfeld M, Chaudhuri G. Estradiol inhibits leukocyte adhesion and transendothelial migration in rabbits in vivo : possible mechanisms for gender differences in atherosclerosis. Circ Res. 1999 Aug 20; 85(4):377-85. PMID: 10455066.
      Citations: 29     Fields:    Translation:AnimalsCells
    77. Amarnani S, Sangrat B, Chaudhuri G. Effects of selected endothelium-dependent vasodilators on fetoplacental vasculature: physiological implications. Am J Physiol. 1999 08; 277(2):H842-7. PMID: 10444513.
      Citations: 4     Fields:    Translation:Humans
    78. Grewal M, Cuevas J, Chaudhuri G, Nathan L. Effects of calcitonin gene-related peptide on vascular resistance in rats: role of sex steroids. Am J Physiol. 1999 06; 276(6):H2063-8. PMID: 10362688.
      Citations: 1     Fields:    Translation:Animals
    79. Pervin S, Singh R, Rosenfeld ME, Navab M, Chaudhuri G, Nathan L. Estradiol suppresses MCP-1 expression In vivo : implications for atherosclerosis. Arterioscler Thromb Vasc Biol. 1998 Oct; 18(10):1575-82. PMID: 9763529.
      Citations: 12     Fields:    Translation:Animals
    80. Nathan L, Chaudhuri G. Antioxidant and prooxidant actions of estrogens: potential physiological and clinical implications. Semin Reprod Endocrinol. 1998; 16(4):309-14. PMID: 10101811.
      Citations: 13     Fields:    Translation:HumansCells
    81. Zhang RS, Guth PH, Scremin OU, Singh R, Pervin S, Chaudhuri G. Regulation of endometrial blood flow in ovariectomized rats: assessment of the role of nitric oxide. Am J Physiol. 1997 10; 273(4):H2009-17. PMID: 9362273.
      Citations: 1     Fields:    Translation:Animals
    82. Brauner R, Laks H, Drinkwater DC, Chaudhuri G, Shvarts O, Drake T, Bhuta S, Mishaly D, Fishbein I, Golomb G. Controlled periadventitial administration of verapamil inhibits neointimal smooth muscle cell proliferation and ameliorates vasomotor abnormalities in experimental vein bypass grafts. J Thorac Cardiovasc Surg. 1997 Jul; 114(1):53-63. PMID: 9240294.
      Citations: 4     Fields:    Translation:Animals
    83. Singh R, Pervin S, Rogers NE, Ignarro LJ, Chaudhuri G. Evidence for the presence of an unusual nitric oxide- and citrulline-producing enzyme in rat kidney. Biochem Biophys Res Commun. 1997 Mar 27; 232(3):672-7. PMID: 9126334.
      Citations: 7     Fields:    Translation:Animals
    84. Chaudhuri G. Scavenger receptor-mediated delivery of antisense mini-exon phosphorothioate oligonucleotide to Leishmania-infected macrophages. Selective and efficient elimination of the parasite. Biochem Pharmacol. 1997 Feb 07; 53(3):385-91. PMID: 9065742.
      Citations: 9     Fields:    Translation:AnimalsCells
    85. Nathan L, Chaudhuri G. Estrogens and atherosclerosis. Annu Rev Pharmacol Toxicol. 1997; 37:477-515. PMID: 9131262.
      Citations: 21     Fields:    Translation:HumansAnimalsCells
    86. Glasgow RE, Buga GM, Ignarro LJ, Chaudhuri G, Heymann MA. Endothelium-derived relaxing factor as a mediator of bradykinin-induced perinatal pulmonary vasodilatation in fetal sheep. Reprod Fertil Dev. 1997; 9(2):213-6. PMID: 9208431.
      Citations: 2     Fields:    Translation:Animals
    87. Seay MB, Heard PL, Chaudhuri G. Surface Zn-proteinase as a molecule for defense of Leishmania mexicana amazonensis promastigotes against cytolysis inside macrophage phagolysosomes. Infect Immun. 1996 Dec; 64(12):5129-37. PMID: 8945556.
      Citations: 20     Fields:    Translation:HumansAnimalsCells
    88. Villalta F, Smith CM, Burns JM, Chaudhuri G, Lima MF. Fab' fragments of a mAb to a member of family 2 of trans-sialidases of Trypanosoma cruzi block trypanosome invasion of host cells and neutralize infection by passive immunization. Ann N Y Acad Sci. 1996 Oct 25; 797:242-5. PMID: 8993367.
      Citations: 5     Fields:    Translation:Animals
    89. Heard PL, Lewis CS, Chaudhuri G. Leishmania mexicana amazonensis: differential display analysis and cloning of mRNAs from attenuated and infective forms. J Eukaryot Microbiol. 1996 Sep-Oct; 43(5):409-15. PMID: 8822812.
      Citations: 5     Fields:    Translation:AnimalsCells
    90. Cohen GA, Hobbs AJ, Fitch RM, Zinner MJ, Chaudhuri G, Ignarro LJ. Nitric oxide regulates endothelium-dependent vasodilator responses in rabbit hindquarters vascular bed in vivo. Am J Physiol. 1996 Jul; 271(1 Pt 2):H133-9. PMID: 8760168.
      Citations: 4     Fields:    Translation:Animals
    91. Farias-Eisner R, Chaudhuri G, Aeberhard E, Fukuto JM. The chemistry and tumoricidal activity of nitric oxide/hydrogen peroxide and the implications to cell resistance/susceptibility. J Biol Chem. 1996 Mar 15; 271(11):6144-51. PMID: 8626402.
      Citations: 26     Fields:    Translation:HumansCells
    92. Onaivi ES, Chakrabarti A, Chaudhuri G. Cannabinoid receptor genes. Prog Neurobiol. 1996 Mar-Apr; 48(4-5):275-305. PMID: 8804112.
      Citations: 5     Fields:    Translation:HumansAnimals
    93. Onaivi ES, Chakrabarti A, Gwebu ET, Chaudhuri G. Neurobehavioral effects of delta 9-THC and cannabinoid (CB1) receptor gene expression in mice. Behav Brain Res. 1995 Dec 14; 72(1-2):115-25. PMID: 8788864.
      Citations: 13     Fields:    Translation:AnimalsCells
    94. Hayashi T, Fukuto JM, Ignarro LJ, Chaudhuri G. Gender differences in atherosclerosis: possible role of nitric oxide. J Cardiovasc Pharmacol. 1995 Nov; 26(5):792-802. PMID: 8637195.
      Citations: 8     Fields:    Translation:Animals
    95. Radziszewski W, Chopra M, Zembowicz A, Gryglewski R, Ignarro LJ, Chaudhuri G. Nitric oxide donors induce extrusion of cyclic GMP from isolated human blood platelets by a mechanism which may be modulated by prostaglandins. Int J Cardiol. 1995 Oct; 51(3):211-20. PMID: 8586470.
      Citations: 1     Fields:    Translation:HumansCells
    96. Barnwell LF, Chaudhuri G, Townsel JG. Cloning and sequencing of a cDNA encoding a novel member of the human brain GABA/noradrenaline neurotransmitter transporter family. Gene. 1995 Jul 04; 159(2):287-8. PMID: 7622069.
      Citations: 5     Fields:    Translation:HumansCells
    97. Nathan L, Cuevas J, Chaudhuri G. The role of nitric oxide in the altered vascular reactivity of pregnancy in the rat. Br J Pharmacol. 1995 Mar; 114(5):955-60. PMID: 7780650.
      Citations: 12     Fields:    Translation:Animals
    98. Gelety TJ, Chaudhuri G. Haemostatic mechanism in the endometrium: role of cyclo-oxygenase products and coagulation factors. Br J Pharmacol. 1995 Mar; 114(5):975-80. PMID: 7780653.
      Citations:    Fields:    Translation:AnimalsCells
    99. Zhang RS, Guth PH, Scremin OU, Chaudhuri G. H2 gas clearance technique for separating rat uterine blood flow into endometrial and myometrial components. Am J Physiol. 1995 Feb; 268(2 Pt 2):R569-75. PMID: 7864254.
      Citations: 1     Fields:    Translation:Animals
    100. Hyun J, Komori Y, Chaudhuri G, Ignarro LJ, Fukuto JM. The protective effect of tetrahydrobiopterin on the nitric oxide-mediated inhibition of purified nitric oxide synthase. Biochem Biophys Res Commun. 1995 Jan 05; 206(1):380-6. PMID: 7529500.
      Citations: 1     Fields:    Translation:AnimalsCells
    101. Fukuto JM, Chaudhuri G. Inhibition of constitutive and inducible nitric oxide synthase: potential selective inhibition. Annu Rev Pharmacol Toxicol. 1995; 35:165-94. PMID: 7541188.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    102. Chakrabarti A, Onaivi ES, Chaudhuri G. Cloning and sequencing of a cDNA encoding the mouse brain-type cannabinoid receptor protein. DNA Seq. 1995; 5(6):385-8. PMID: 8777318.
      Citations: 16     Fields:    Translation:HumansAnimalsCells
    103. Farias-Eisner R, Sherman MP, Aeberhard E, Chaudhuri G. Nitric oxide is an important mediator for tumoricidal activity in vivo. Proc Natl Acad Sci U S A. 1994 Sep 27; 91(20):9407-11. PMID: 7937779.
      Citations: 29     Fields:    Translation:HumansAnimalsCells
    104. Chaudhuri G, Cuevas J, Buga GM, Ignarro LJ. NO is more important than PGI2 in maintaining low vascular tone in feto-placental vessels. Am J Physiol. 1993 Dec; 265(6 Pt 2):H2036-43. PMID: 8285242.
      Citations: 5     Fields:    Translation:Animals
    105. Furuya K, Chaudhuri G. Estradiol does not influence myocardial superoxide dismutase activity in rabbits. J Cardiovasc Pharmacol. 1993 Jul; 22(1):65-8. PMID: 7690098.
      Citations: 2     Fields:    Translation:Animals
    106. Hayashi T, Fukuto JM, Ignarro LJ, Chaudhuri G. Basal release of nitric oxide from aortic rings is greater in female rabbits than in male rabbits: implications for atherosclerosis. Proc Natl Acad Sci U S A. 1992 Dec 01; 89(23):11259-63. PMID: 1454805.
      Citations: 40     Fields:    Translation:Animals
    107. Varela AF, Runge A, Ignarro LJ, Chaudhuri G. Nitric oxide and prostacyclin inhibit fetal platelet aggregation: a response similar to that observed in adults. Am J Obstet Gynecol. 1992 Dec; 167(6):1599-604. PMID: 1471673.
      Citations: 1     Fields:    Translation:HumansCells
    108. Gelety TJ, Chaudhuri G. Prostaglandins in the ovary and fallopian tube. Baillieres Clin Obstet Gynaecol. 1992 Dec; 6(4):707-29. PMID: 1477996.
      Citations:    Fields:    Translation:HumansAnimals
    109. Fukuto JM, Chiang K, Hszieh R, Wong P, Chaudhuri G. The pharmacological activity of nitroxyl: a potent vasodilator with activity similar to nitric oxide and/or endothelium-derived relaxing factor. J Pharmacol Exp Ther. 1992 Nov; 263(2):546-51. PMID: 1331403.
      Citations: 44     Fields:    Translation:AnimalsCells
    110. Fukuto JM, Wallace GC, Hszieh R, Chaudhuri G. Chemical oxidation of N-hydroxyguanidine compounds. Release of nitric oxide, nitroxyl and possible relationship to the mechanism of biological nitric oxide generation. Biochem Pharmacol. 1992 Feb 04; 43(3):607-13. PMID: 1540216.
      Citations: 22     Fields:    Translation:AnimalsCells
    111. Vargas HM, Cuevas JM, Ignarro LJ, Chaudhuri G. Comparison of the inhibitory potencies of N(G)-methyl-, N(G)-nitro- and N(G)-amino-L-arginine on EDRF function in the rat: evidence for continuous basal EDRF release. J Pharmacol Exp Ther. 1991 Jun; 257(3):1208-15. PMID: 1646327.
      Citations: 17     Fields:    Translation:Animals
    112. Ross G, Chaudhuri G, Ignarro LJ, Chyu KY. Acetylcholine vasodilation of resistance vessels in vivo may not entirely depend on newly synthesized nitric oxide. Eur J Pharmacol. 1991 Mar 26; 195(2):291-3. PMID: 1874277.
      Citations: 5     Fields:    Translation:Animals
    113. Chaudhuri G, Furuya K. Endothelium-derived vasoactive substances in fetal placental vessels. Semin Perinatol. 1991 Feb; 15(1):63-7. PMID: 2063231.
      Citations:    Fields:    Translation:HumansAnimals
    114. Chaudhuri G, Buga GM, Gold ME, Wood KS, Ignarro LJ. Characterization and actions of human umbilical endothelium derived relaxing factor. Br J Pharmacol. 1991 Feb; 102(2):331-6. PMID: 1849765.
      Citations: 9     Fields:    Translation:HumansAnimals
    115. Vargas HM, Ignarro LJ, Chaudhuri G. Physiological release of nitric oxide is dependent on the level of vascular tone. Eur J Pharmacol. 1990 Nov 13; 190(3):393-7. PMID: 2272376.
      Citations: 10     Fields:    Translation:AnimalsCells
    116. Gold ME, Buga GM, Wood KS, Byrns RE, Chaudhuri G, Ignarro LJ. Antagonistic modulatory roles of magnesium and calcium on release of endothelium-derived relaxing factor and smooth muscle tone. Circ Res. 1990 Feb; 66(2):355-66. PMID: 2153470.
      Citations: 11     Fields:    Translation:AnimalsCells
    117. Buga GM, Gold ME, Wood KS, Chaudhuri G, Ignarro LJ. Endothelium-derived nitric oxide relaxes nonvascular smooth muscle. Eur J Pharmacol. 1989 Feb 14; 161(1):61-72. PMID: 2542037.
      Citations: 23     Fields:    Translation:HumansAnimals
    118. Ignarro LJ, Gold ME, Buga GM, Byrns RE, Wood KS, Chaudhuri G, Frank G. Basic polyamino acids rich in arginine, lysine, or ornithine cause both enhancement of and refractoriness to formation of endothelium-derived nitric oxide in pulmonary artery and vein. Circ Res. 1989 Feb; 64(2):315-29. PMID: 2492213.
      Citations: 11     Fields:    Translation:Animals
    119. Ignarro LJ, Buga GM, Byrns RE, Wood KS, Chaudhuri G. Endothelium-derived relaxing factor and nitric oxide possess identical pharmacologic properties as relaxants of bovine arterial and venous smooth muscle. J Pharmacol Exp Ther. 1988 Jul; 246(1):218-26. PMID: 2839663.
      Citations: 20     Fields:    Translation:Animals
    120. Ignarro LJ, Buga GM, Chaudhuri G. EDRF generation and release from perfused bovine pulmonary artery and vein. Eur J Pharmacol. 1988 Apr 27; 149(1-2):79-88. PMID: 3135198.
      Citations: 14     Fields:    Translation:Animals
    121. Chaudhuri G, Steingold KA, Pardridge WM, Judd HL. TeBG- and CBG-bound steroid hormones in rabbits are available for influx into uterus in vivo. Am J Physiol. 1988 Jan; 254(1 Pt 1):E79-83. PMID: 3337226.
      Citations:    Fields:    Translation:Animals
    122. Ignarro LJ, Byrns RE, Buga GM, Wood KS, Chaudhuri G. Pharmacological evidence that endothelium-derived relaxing factor is nitric oxide: use of pyrogallol and superoxide dismutase to study endothelium-dependent and nitric oxide-elicited vascular smooth muscle relaxation. J Pharmacol Exp Ther. 1988 Jan; 244(1):181-9. PMID: 2826766.
      Citations: 36     Fields:    Translation:Animals
    123. Ignarro LJ, Buga GM, Wood KS, Byrns RE, Chaudhuri G. Endothelium-derived relaxing factor produced and released from artery and vein is nitric oxide. Proc Natl Acad Sci U S A. 1987 Dec; 84(24):9265-9. PMID: 2827174.
      Citations: 745     Fields:    Translation:Animals
    124. Steingold KA, Pardridge WM, Judd HL, Chaudhuri G. The effects of membrane permeability and binding by human serum proteins on steroid influx into the rabbit uterus. Am J Obstet Gynecol. 1987 Dec; 157(6):1543-9. PMID: 3425659.
      Citations:    Fields:    Translation:HumansAnimalsCells
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