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Yohannes Tesfaigzi

TitleDirector of COPD Program
Faculty RankProfessor
InstitutionMorehouse School of Medicine
DepartmentPulmonary Division
Address9495 Ridgecrest Dr. SE
Albquerque NM 87108
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Polverino F, Wu TD, Rojas-Quintero J, Wang X, Mayo J, Tomchaney M, Tram J, Packard S, Zhang D, Cleveland KH, Cordoba-Lanus E, Owen CA, Fawzy A, Kinney GL, Hersh CP, Hansel NN, Doubleday K, Sauler M, Tesfaigzi Y, Ledford JG, Casanova C, Zmijewski J, Konhilas J, Langlais PR, Schnellmann R, Rahman I, McCormack M, Celli B. Metformin: Experimental and Clinical Evidence for a Potential Role in Emphysema Treatment. Am J Respir Crit Care Med. 2021 09 15; 204(6):651-666. PMID: 34033525.
      Citations: 2     Fields:    Translation:HumansAnimals
    2. Lin X, Li Y, Gong L, Yun JH, Xu S, Tesfaigzi Y, Qiao D, Zhou X. Tempo-spatial regulation of the Wnt pathway by FAM13A modulates the stemness of alveolar epithelial progenitors. EBioMedicine. 2021 Jul; 69:103463. PMID: 34224973.
      Citations: 1     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    3. Soni S, Jiang Y, Tesfaigzi Y, Hornick JL, Çataltepe S. Comparative analysis of ACE2 protein expression in rodent, non-human primate, and human respiratory tract at baseline and after injury: A conundrum for COVID-19 pathogenesis. PLoS One. 2021; 16(2):e0247510. PMID: 33626084.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    4. Tomchaney M, Contoli M, Mayo J, Baraldo S, Shuaizhi L, Cabel CR, Bull DA, Lick S, Malo J, Knoper S, Kim SS, Tram J, Rojas-Quintero J, Kraft M, Ledford J, Tesfaigzi Y, Martinez FD, Thorne CA, Kheradmand F, Campos SK, Papi A, Polverino F. Paradoxical effects of cigarette smoke and COPD on SARS-CoV2 infection and disease. bioRxiv. 2020 Dec 07. PMID: 33330864.
    5. Lam HC, Cloonan SM, Bhashyam AR, Haspel JA, Singh A, Sathirapongsasuti JF, Cervo M, Yao H, Chung AL, Mizumura K, An CH, Shan B, Franks JM, Haley KJ, Owen CA, Tesfaigzi Y, Washko GR, Quackenbush J, Silverman EK, Rahman I, Kim HP, Mahmood A, Biswal SS, Ryter SW, Choi AM. Histone deacetylase 6-mediated selective autophagy regulates COPD-associated cilia dysfunction. J Clin Invest. 2020 11 02; 130(11):6189. PMID: 33136096.
      Citations:    Fields:    
    6. Mebratu YA, Negasi ZH, Dutta S, Rojas-Quintero J, Tesfaigzi Y. Adaptation of Proteasomes and Lysosomes to Cellular Environments. Cells. 2020 10 01; 9(10). PMID: 33019542.
      Citations: 1     Fields:    Translation:HumansCells
    7. Wang X, Rojas-Quintero J, Zhang D, Nakajima T, Walker KH, Peh HY, Li Y, Fucci QA, Tesfaigzi Y, Owen CA. A disintegrin and metalloproteinase domain-15 deficiency leads to exaggerated cigarette smoke-induced chronic obstructive pulmonary disease (COPD)-like disease in mice. Mucosal Immunol. 2021 03; 14(2):342-356. PMID: 32690871.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    8. Tessema M, Tassew DD, Yingling CM, Do K, Picchi MA, Wu G, Petersen H, Randell S, Lin Y, Belinsky SA, Tesfaigzi Y. Identification of novel epigenetic abnormalities as sputum biomarkers for lung cancer risk among smokers and COPD patients. Lung Cancer. 2020 08; 146:189-196. PMID: 32559455.
      Citations: 3     Fields:    Translation:HumansCells
    9. Ono JG, Kim BI, Zhao Y, Christos PJ, Tesfaigzi Y, Worgall TS, Worgall S. Decreased sphingolipid synthesis in children with 17q21 asthma-risk genotypes. J Clin Invest. 2020 02 03; 130(2):921-926. PMID: 31929190.
      Citations: 16     Fields:    Translation:HumansCellsCTClinical Trials
    10. Sidhaye VK, Wu M, Tesfaigzi Y. Jumping on the Single-Cell RNA-Sequencing Bandwagon: Take Care Not to Put the Cart before the Horse. Am J Respir Cell Mol Biol. 2020 02; 62(2):267. PMID: 32003599.
      Citations:    Fields:    Translation:Humans
    11. Pinto-Plata V, Casanova C, Divo M, Tesfaigzi Y, Calhoun V, Sui J, Polverino F, Priolo C, Petersen H, de Torres JP, Marin JM, Owen CA, Baz R, Cordova E, Celli B. Plasma metabolomics and clinical predictors of survival differences in COPD patients. Respir Res. 2019 Oct 15; 20(1):219. PMID: 31615518.
      Citations: 7     Fields:    Translation:Humans
    12. Wang X, Rojas-Quintero J, Wilder J, Tesfaigzi Y, Zhang D, Owen CA. Tissue Inhibitor of Metalloproteinase-1 Promotes Polymorphonuclear Neutrophil (PMN) Pericellular Proteolysis by Anchoring Matrix Metalloproteinase-8 and -9 to PMN Surfaces. J Immunol. 2019 06 01; 202(11):3267-3281. PMID: 31019060.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    13. Sakornsakolpat P, Prokopenko D, Lamontagne M, Reeve NF, Guyatt AL, Jackson VE, Shrine N, Qiao D, Bartz TM, Kim DK, Lee MK, Latourelle JC, Li X, Morrow JD, Obeidat M, Wyss AB, Bakke P, Barr RG, Beaty TH, Belinsky SA, Brusselle GG, Crapo JD, de Jong K, DeMeo DL, Fingerlin TE, Gharib SA, Gulsvik A, Hall IP, Hokanson JE, Kim WJ, Lomas DA, London SJ, Meyers DA, O'Connor GT, Rennard SI, Schwartz DA, Sliwinski P, Sparrow D, Strachan DP, Tal-Singer R, Tesfaigzi Y, Vestbo J, Vonk JM, Yim JJ, Zhou X, Bossé Y, Manichaikul A, Lahousse L, Silverman EK, Boezen HM, Wain LV, Tobin MD, Hobbs BD, Cho MH. Genetic landscape of chronic obstructive pulmonary disease identifies heterogeneous cell-type and phenotype associations. Nat Genet. 2019 03; 51(3):494-505. PMID: 30804561.
      Citations: 66     Fields:    Translation:Humans
    14. Voic H, Li X, Jang JH, Zou C, Sundd P, Alder J, Rojas M, Chandra D, Randell S, Mallampalli RK, Tesfaigzi Y, Ryba T, Nyunoya T. RNA sequencing identifies common pathways between cigarette smoke exposure and replicative senescence in human airway epithelia. BMC Genomics. 2019 Jan 09; 20(1):22. PMID: 30626320.
      Citations: 1     Fields:    Translation:HumansCells
    15. Petersen H, Sood A, Polverino F, Owen CA, Pinto-Plata V, Celli BR, Tesfaigzi Y. The Course of Lung Function in Middle-aged Heavy Smokers: Incidence and Time to Early Onset of Chronic Obstructive Pulmonary Disease. Am J Respir Crit Care Med. 2018 12 01; 198(11):1449-1451. PMID: 30114375.
      Citations: 4     Fields:    Translation:Humans
    16. Polverino F, Rojas-Quintero J, Wang X, Petersen H, Zhang L, Gai X, Higham A, Zhang D, Gupta K, Rout A, Yambayev I, Pinto-Plata V, Sholl LM, Cunoosamy D, Celli BR, Goldring J, Singh D, Tesfaigzi Y, Wedzicha J, Olsson H, Owen CA. A Disintegrin and Metalloproteinase Domain-8: A Novel Protective Proteinase in Chronic Obstructive Pulmonary Disease. Am J Respir Crit Care Med. 2018 11 15; 198(10):1254-1267. PMID: 29750543.
      Citations: 10     Fields:    Translation:HumansAnimals
    17. Abukhalaf J, Davidson R, Villalobos N, Meek P, Petersen H, Sood A, Tesfaigzi Y, Vazquez Guillamet R. Chronic obstructive pulmonary disease mortality, a competing risk analysis. Clin Respir J. 2018 Nov; 12(11):2598-2605. PMID: 30257066.
      Citations: 1     Fields:    Translation:Humans
    18. Petersen H, Vazquez Guillamet R, Meek P, Sood A, Tesfaigzi Y. Early Endotyping: A Chance for Intervention in Chronic Obstructive Pulmonary Disease. Am J Respir Cell Mol Biol. 2018 07; 59(1):13-17. PMID: 29522352.
      Citations: 6     Fields:    Translation:HumansAnimals
    19. Mebratu YA, Tesfaigzi Y. IL-17 Plays a Role in Respiratory Syncytial Virus-induced Lung Inflammation and Emphysema in Elastase and LPS-injured Mice. Am J Respir Cell Mol Biol. 2018 06; 58(6):717-726. PMID: 29314865.
      Citations: 14     Fields:    Translation:Animals
    20. Mebratu YA, Tesfaigzi Y. Does the BCL-2 family member BIK control lung carcinogenesis? Mol Cell Oncol. 2018; 5(4):e1435182. PMID: 30250907.
    21. Vazquez Guillamet R, Petersen H, Meek P, Sood A, Tesfaigzi Y. Grading Severity of Productive Cough Based on Symptoms and Airflow Obstruction. COPD. 2018 04; 15(2):206-213. PMID: 29697285.
      Citations:    Fields:    Translation:HumansPHPublic Health
    22. Vazquez Guillamet R, Petersen H, Meek PM, Tesfaigzi Y, Sood A. Normalization of FEV1/FVC Ratio to Greater Than 0.7 Does Not Equal Resolution of Disease. Am J Respir Crit Care Med. 2018 03 15; 197(6):834-835. PMID: 29106290.
      Citations: 1     Fields:    Translation:Humans
    23. Zhang C, Jones JT, Chand HS, Wathelet MG, Evans CM, Dickey B, Xiang J, Mebratu YA, Tesfaigzi Y. Noxa/HSP27 complex delays degradation of ubiquitylated IkBa in airway epithelial cells to reduce pulmonary inflammation. Mucosal Immunol. 2018 05; 11(3):741-751. PMID: 29363670.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    24. Chand HS, Harris JF, Tesfaigzi Y. IL-13 in LPS-Induced Inflammation Causes Bcl-2 Expression to Sustain Hyperplastic Mucous cells. Sci Rep. 2018 01 11; 8(1):436. PMID: 29323189.
      Citations: 7     Fields:    Translation:Animals
    25. Sood A, Assad NA, Barnes PJ, Churg A, Gordon SB, Harrod KS, Irshad H, Kurmi OP, Martin WJ, Meek P, Mortimer K, Noonan CW, Perez-Padilla R, Smith KR, Tesfaigzi Y, Ward T, Balmes J. ERS/ATS workshop report on respiratory health effects of household air pollution. Eur Respir J. 2018 01; 51(1). PMID: 29301918.
      Citations: 19     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    26. Leng S, Picchi MA, Tesfaigzi Y, Wu G, Gauderman WJ, Xu F, Gilliland FD, Belinsky SA. Dietary nutrients associated with preservation of lung function in Hispanic and non-Hispanic white smokers from New Mexico. Int J Chron Obstruct Pulmon Dis. 2017; 12:3171-3181. PMID: 29133979.
      Citations: 8     Fields:    Translation:Humans
    27. Mebratu YA, Leyva-Baca I, Wathelet MG, Lacey N, Chand HS, Choi AMK, Tesfaigzi Y. Bik reduces hyperplastic cells by increasing Bak and activating DAPk1 to juxtapose ER and mitochondria. Nat Commun. 2017 10 06; 8(1):803. PMID: 28986568.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    28. Diaz AA, Rahaghi FN, Doyle TJ, Young TP, Maclean ES, Martinez CH, San José Estépar R, Guerra S, Tesfaigzi Y, Rosas IO, Washko GR, Wilson DO. Differences in Respiratory Symptoms and Lung Structure Between Hispanic and Non-Hispanic White Smokers: A Comparative Study. Chronic Obstr Pulm Dis. 2017 Sep 05; 4(4):297-304. PMID: 29354674.
    29. Black C, Tesfaigzi Y, Bassein JA, Miller LA. Wildfire smoke exposure and human health: Significant gaps in research for a growing public health issue. Environ Toxicol Pharmacol. 2017 Oct; 55:186-195. PMID: 28892756.
      Citations: 29     Fields:    Translation:HumansAnimalsPHPublic Health
    30. Chand HS, Mebratu YA, Kuehl PJ, Tesfaigzi Y. Blocking Bcl-2 resolves IL-13-mediated mucous cell hyperplasia in a Bik-dependent manner. J Allergy Clin Immunol. 2017 11; 140(5):1456-1459.e9. PMID: 28784260.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    31. Castaldi PJ, Benet M, Petersen H, Rafaels N, Finigan J, Paoletti M, Marike Boezen H, Vonk JM, Bowler R, Pistolesi M, Puhan MA, Anto J, Wauters E, Lambrechts D, Janssens W, Bigazzi F, Camiciottoli G, Cho MH, Hersh CP, Barnes K, Rennard S, Boorgula MP, Dy J, Hansel NN, Crapo JD, Tesfaigzi Y, Agusti A, Silverman EK, Garcia-Aymerich J. Do COPD subtypes really exist? COPD heterogeneity and clustering in 10 independent cohorts. Thorax. 2017 11; 72(11):998-1006. PMID: 28637835.
      Citations: 20     Fields:    Translation:Humans
    32. Polverino F, Laucho-Contreras ME, Petersen H, Bijol V, Sholl LM, Choi ME, Divo M, Pinto-Plata V, Chetta A, Tesfaigzi Y, Celli BR, Owen CA. A Pilot Study Linking Endothelial Injury in Lungs and Kidneys in Chronic Obstructive Pulmonary Disease. Am J Respir Crit Care Med. 2017 06 01; 195(11):1464-1476. PMID: 28085500.
      Citations: 32     Fields:    Translation:HumansAnimals
    33. Jones JT, Tassew DD, Herrera LK, Walton-Filipczak SR, Montera MA, Chand HS, Delgado M, Mebratu YA, Tesfaigzi Y. Extent of allergic inflammation depends on intermittent versus continuous sensitization to house dust mite. Inhal Toxicol. 2017 02; 29(3):106-112. PMID: 28413916.
      Citations:    Fields:    Translation:AnimalsCells
    34. Hobbs BD, de Jong K, Lamontagne M, Bossé Y, Shrine N, Artigas MS, Wain LV, Hall IP, Jackson VE, Wyss AB, London SJ, North KE, Franceschini N, Strachan DP, Beaty TH, Hokanson JE, Crapo JD, Castaldi PJ, Chase RP, Bartz TM, Heckbert SR, Psaty BM, Gharib SA, Zanen P, Lammers JW, Oudkerk M, Groen HJ, Locantore N, Tal-Singer R, Rennard SI, Vestbo J, Timens W, Paré PD, Latourelle JC, Dupuis J, O'Connor GT, Wilk JB, Kim WJ, Lee MK, Oh YM, Vonk JM, de Koning HJ, Leng S, Belinsky SA, Tesfaigzi Y, Manichaikul A, Wang XQ, Rich SS, Barr RG, Sparrow D, Litonjua AA, Bakke P, Gulsvik A, Lahousse L, Brusselle GG, Stricker BH, Uitterlinden AG, Ampleford EJ, Bleecker ER, Woodruff PG, Meyers DA, Qiao D, Lomas DA, Yim JJ, Kim DK, Hawrylkiewicz I, Sliwinski P, Hardin M, Fingerlin TE, Schwartz DA, Postma DS, MacNee W, Tobin MD, Silverman EK, Boezen HM, Cho MH. Genetic loci associated with chronic obstructive pulmonary disease overlap with loci for lung function and pulmonary fibrosis. Nat Genet. 2017 Mar; 49(3):426-432. PMID: 28166215.
      Citations: 106     Fields:    Translation:Humans
    35. Jang JH, Chand HS, Bruse S, Doyle-Eisele M, Royer C, McDonald J, Qualls C, Klingelhutz AJ, Lin Y, Mallampalli R, Tesfaigzi Y, Nyunoya T. Connective Tissue Growth Factor Promotes Pulmonary Epithelial Cell Senescence and Is Associated with COPD Severity. COPD. 2017 Apr; 14(2):228-237. PMID: 28026993.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    36. Sood A, Petersen H, Qualls C, Meek PM, Vazquez-Guillamet R, Celli BR, Tesfaigzi Y. Spirometric variability in smokers: transitions in COPD diagnosis in a five-year longitudinal study. Respir Res. 2016 11 10; 17(1):147. PMID: 27832774.
      Citations: 10     Fields:    Translation:Humans
    37. Chand HS, Mebratu YA, Montera M, Tesfaigzi Y. T cells suppress memory-dependent rapid mucous cell metaplasia in mouse airways. Respir Res. 2016 10 20; 17(1):132. PMID: 27765038.
      Citations: 1     Fields:    Translation:AnimalsCells
    38. Mebratu YA, Smith KR, Agga GE, Tesfaigzi Y. Inflammation and emphysema in cigarette smoke-exposed mice when instilled with poly (I:C) or infected with influenza A or respiratory syncytial viruses. Respir Res. 2016 07 01; 17(1):75. PMID: 27363862.
      Citations: 3     Fields:    Translation:AnimalsCells
    39. Diaz AA, Petersen H, Meek P, Sood A, Celli B, Tesfaigzi Y. Differences in Health-Related Quality of Life Between New Mexican Hispanic and Non-Hispanic White Smokers. Chest. 2016 Oct; 150(4):869-876. PMID: 27321735.
      Citations: 5     Fields:    Translation:Humans
    40. Mebratu YA, Tipper J, Chand HS, Walton S, Harrod KS, Tesfaigzi Y. Bik Mediates Caspase-Dependent Cleavage of Viral Proteins to Promote Influenza A Virus Infection. Am J Respir Cell Mol Biol. 2016 05; 54(5):664-73. PMID: 26437021.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    41. Behrsing H, Raabe H, Manuppello J, Bombick B, Curren R, Sullivan K, Sethi S, Phipps R, Tesfaigzi Y, Yan S, D'Ruiz C, Tarran R, Constant S, Phillips G, Gaça M, Hayden P, Cao X, Mathis C, Hoeng J, Braun A, Hill E. Assessment of in vitro COPD models for tobacco regulatory science: Workshop proceedings, conclusions and paths forward for in vitro model use. Altern Lab Anim. 2016 May; 44(2):129-66. PMID: 27256455.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    42. Laucho-Contreras ME, Polverino F, Tesfaigzi Y, Pilon A, Celli BR, Owen CA. Club Cell Protein 16 (CC16) Augmentation: A Potential Disease-modifying Approach for Chronic Obstructive Pulmonary Disease (COPD). Expert Opin Ther Targets. 2016 Jul; 20(7):869-83. PMID: 26781659.
      Citations: 22     Fields:    Translation:HumansAnimalsCells
    43. Singh SP, Chand HS, Gundavarapu S, Saeed AI, Langley RJ, Tesfaigzi Y, Mishra NC, Sopori ML. HIF-1a Plays a Critical Role in the Gestational Sidestream Smoke-Induced Bronchopulmonary Dysplasia in Mice. PLoS One. 2015; 10(9):e0137757. PMID: 26361040.
      Citations: 5     Fields:    Translation:AnimalsCellsPHPublic Health
    44. Meek PM, Petersen H, Washko GR, Diaz AA, Klm V, Sood A, Tesfaigzi Y. Chronic Bronchitis Is Associated With Worse Symptoms and Quality of Life Than Chronic Airflow Obstruction. Chest. 2015 Aug; 148(2):408-416. PMID: 25741880.
      Citations: 15     Fields:    Translation:Humans
    45. Tessema M, Yingling CM, Picchi MA, Wu G, Liu Y, Weissfeld JL, Siegfried JM, Tesfaigzi Y, Belinsky SA. Epigenetic Repression of CCDC37 and MAP1B Links Chronic Obstructive Pulmonary Disease to Lung Cancer. J Thorac Oncol. 2015 Aug; 10(8):1181-8. PMID: 26200272.
      Citations: 14     Fields:    Translation:HumansCells
    46. Petersen H, Leng S, Belinsky SA, Miller BE, Tal-Singer R, Owen CA, Celli B, Tesfaigzi Y. Low plasma CC16 levels in smokers are associated with a higher risk for chronic bronchitis. Eur Respir J. 2015 Nov; 46(5):1501-3. PMID: 26160869.
      Citations: 8     Fields:    Translation:Humans
    47. Lange P, Celli B, Agustí A, Boje Jensen G, Divo M, Faner R, Guerra S, Marott JL, Martinez FD, Martinez-Camblor P, Meek P, Owen CA, Petersen H, Pinto-Plata V, Schnohr P, Sood A, Soriano JB, Tesfaigzi Y, Vestbo J. Lung-Function Trajectories Leading to Chronic Obstructive Pulmonary Disease. N Engl J Med. 2015 Jul 09; 373(2):111-22. PMID: 26154786.
      Citations: 258     Fields:    Translation:Humans
    48. Awji EG, Seagrave JC, Tesfaigzi Y. Correlation of Cigarette Smoke-Induced Pulmonary Inflammation and Emphysema in C3H and C57Bl/6 Mice. Toxicol Sci. 2015 Sep; 147(1):75-83. PMID: 26032511.
      Citations: 6     Fields:    Translation:AnimalsCells
    49. Awji EG, Chand H, Bruse S, Smith KR, Colby JK, Mebratu Y, Levy BD, Tesfaigzi Y. Wood smoke enhances cigarette smoke-induced inflammation by inducing the aryl hydrocarbon receptor repressor in airway epithelial cells. Am J Respir Cell Mol Biol. 2015 Mar; 52(3):377-86. PMID: 25137396.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    50. Chen W, Brehm JM, Manichaikul A, Cho MH, Boutaoui N, Yan Q, Burkart KM, Enright PL, Rotter JI, Petersen H, Leng S, Obeidat M, Bossé Y, Brandsma CA, Hao K, Rich SS, Powell R, Avila L, Soto-Quiros M, Silverman EK, Tesfaigzi Y, Barr RG, Celedón JC. A genome-wide association study of chronic obstructive pulmonary disease in Hispanics. Ann Am Thorac Soc. 2015 Mar; 12(3):340-8. PMID: 25584925.
      Citations: 14     Fields:    Translation:Humans
    51. Leng S, Liu Y, Weissfeld JL, Thomas CL, Han Y, Picchi MA, Edlund CK, Willink RP, Gaither Davis AL, Do KC, Nukui T, Zhang X, Burki EA, Van Den Berg D, Romkes M, Gauderman WJ, Crowell RE, Tesfaigzi Y, Stidley CA, Amos CI, Siegfried JM, Gilliland FD, Belinsky SA. 15q12 variants, sputum gene promoter hypermethylation, and lung cancer risk: a GWAS in smokers. J Natl Cancer Inst. 2015 Feb 23; 107(5). PMID: 25713168.
      Citations: 13     Fields:    Translation:HumansCells
    52. Laucho-Contreras ME, Polverino F, Gupta K, Taylor KL, Kelly E, Pinto-Plata V, Divo M, Ashfaq N, Petersen H, Stripp B, Pilon AL, Tesfaigzi Y, Celli BR, Owen CA. Protective role for club cell secretory protein-16 (CC16) in the development of COPD. Eur Respir J. 2015 Jun; 45(6):1544-56. PMID: 25700379.
      Citations: 43     Fields:    Translation:HumansAnimals
    53. Polverino F, Doyle-Eisele M, McDonald J, Wilder JA, Royer C, Laucho-Contreras M, Kelly EM, Divo M, Pinto-Plata V, Mauderly J, Celli BR, Tesfaigzi Y, Owen CA. A novel nonhuman primate model of cigarette smoke-induced airway disease. Am J Pathol. 2015 Mar; 185(3):741-55. PMID: 25542772.
      Citations: 21     Fields:    Translation:Animals
    54. Chand HS, Montano G, Huang X, Randell SH, Mebratu Y, Petersen H, Tesfaigzi Y. A genetic variant of p53 restricts the mucous secretory phenotype by regulating SPDEF and Bcl-2 expression. Nat Commun. 2014 Nov 27; 5:5567. PMID: 25429397.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    55. Moon HG, Kim SH, Gao J, Quan T, Qin Z, Osorio JC, Rosas IO, Wu M, Tesfaigzi Y, Jin Y. CCN1 secretion and cleavage regulate the lung epithelial cell functions after cigarette smoke. Am J Physiol Lung Cell Mol Physiol. 2014 Aug 15; 307(4):L326-37. PMID: 24973403.
      Citations: 40     Fields:    Translation:HumansAnimalsCells
    56. Meek PM, Sood A, Petersen H, Belinsky SA, Tesfaigzi Y. Epigenetic change (GATA-4 gene methylation) is associated with health status in chronic obstructive pulmonary disease. Biol Res Nurs. 2015 Mar; 17(2):191-8. PMID: 24973415.
      Citations: 5     Fields:    Translation:HumansCells
    57. Craig VJ, Polverino F, Laucho-Contreras ME, Shi Y, Liu Y, Osorio JC, Tesfaigzi Y, Pinto-Plata V, Gochuico BR, Rosas IO, Owen CA. Mononuclear phagocytes and airway epithelial cells: novel sources of matrix metalloproteinase-8 (MMP-8) in patients with idiopathic pulmonary fibrosis. PLoS One. 2014; 9(5):e97485. PMID: 24828408.
      Citations: 16     Fields:    Translation:HumansCells
    58. Sood A, Petersen H, Meek P, Tesfaigzi Y. Reply from the authors. Am J Respir Crit Care Med. 2014 Apr 01; 189(7):871. PMID: 24684365.
      Citations:    Fields:    Translation:Humans
    59. Chen W, Brehm JM, Boutaoui N, Soto-Quiros M, Avila L, Celli BR, Bruse S, Tesfaigzi Y, Celedón JC. Native American ancestry, lung function, and COPD in Costa Ricans. Chest. 2014 Apr; 145(4):704-710. PMID: 24306962.
      Citations: 13     Fields:    Translation:Humans
    60. Petersen H, Sood A, Meek PM, Shen X, Cheng Y, Belinsky SA, Owen CA, Washko G, Pinto-Plata V, Kelly E, Celli B, Tesfaigzi Y. Rapid lung function decline in smokers is a risk factor for COPD and is attenuated by angiotensin-converting enzyme inhibitor use. Chest. 2014 Apr; 145(4):695-703. PMID: 24008986.
      Citations: 25     Fields:    Translation:Humans
    61. Nyunoya T, Mebratu Y, Contreras A, Delgado M, Chand HS, Tesfaigzi Y. Molecular processes that drive cigarette smoke-induced epithelial cell fate of the lung. Am J Respir Cell Mol Biol. 2014 Mar; 50(3):471-82. PMID: 24111585.
      Citations: 34     Fields:    Translation:HumansAnimalsCells
    62. Sood A, Petersen H, Meek P, Tesfaigzi Y. Spirometry and health status worsen with weight gain in obese smokers but improve in normal-weight smokers. Am J Respir Crit Care Med. 2014 Feb 01; 189(3):274-81. PMID: 24274793.
      Citations: 6     Fields:    Translation:Humans
    63. Bruse S, Petersen H, Weissfeld J, Picchi M, Willink R, Do K, Siegfried J, Belinsky SA, Tesfaigzi Y. Increased methylation of lung cancer-associated genes in sputum DNA of former smokers with chronic mucous hypersecretion. Respir Res. 2014 Jan 09; 15:2. PMID: 24405663.
      Citations: 10     Fields:    Translation:HumansCells
    64. Jang JH, Bruse S, Liu Y, Duffy V, Zhang C, Oyamada N, Randell S, Matsumoto A, Thompson DC, Lin Y, Vasiliou V, Tesfaigzi Y, Nyunoya T. Aldehyde dehydrogenase 3A1 protects airway epithelial cells from cigarette smoke-induced DNA damage and cytotoxicity. Free Radic Biol Med. 2014 Mar; 68:80-6. PMID: 24316006.
      Citations: 16     Fields:    Translation:HumansCells
    65. Delgado M, Tesfaigzi Y. Is BMF central for anoikis and autophagy? Autophagy. 2014 Jan; 10(1):168-9. PMID: 24225781.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    66. Lam HC, Cloonan SM, Bhashyam AR, Haspel JA, Singh A, Sathirapongsasuti JF, Cervo M, Yao H, Chung AL, Mizumura K, An CH, Shan B, Franks JM, Haley KJ, Owen CA, Tesfaigzi Y, Washko GR, Quackenbush J, Silverman EK, Rahman I, Kim HP, Mahmood A, Biswal SS, Ryter SW, Choi AM. Histone deacetylase 6-mediated selective autophagy regulates COPD-associated cilia dysfunction. J Clin Invest. 2013 Dec; 123(12):5212-30. PMID: 24200693.
      Citations: 126     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    67. Delgado M, Tesfaigzi Y. BH3-only proteins, Bmf and Bim, in autophagy. Cell Cycle. 2013 Nov 15; 12(22):3453-4. PMID: 24107625.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    68. Knolle MD, Nakajima T, Hergrueter A, Gupta K, Polverino F, Craig VJ, Fyfe SE, Zahid M, Permaul P, Cernadas M, Montano G, Tesfaigzi Y, Sholl L, Kobzik L, Israel E, Owen CA. Adam8 limits the development of allergic airway inflammation in mice. J Immunol. 2013 Jun 15; 190(12):6434-49. PMID: 23670189.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    69. Contreras AU, Mebratu Y, Delgado M, Montano G, Hu CA, Ryter SW, Choi AM, Lin Y, Xiang J, Chand H, Tesfaigzi Y. Deacetylation of p53 induces autophagy by suppressing Bmf expression. J Cell Biol. 2013 Apr 29; 201(3):427-37. PMID: 23629966.
      Citations: 22     Fields:    Translation:HumansAnimalsCells
    70. Liu Y, Nyunoya T, Leng S, Belinsky SA, Tesfaigzi Y, Bruse S. Softwares and methods for estimating genetic ancestry in human populations. Hum Genomics. 2013 Jan 05; 7:1. PMID: 23289408.
      Citations: 32     Fields:    Translation:Humans
    71. Chand HS, Woldegiorgis Z, Schwalm K, McDonald J, Tesfaigzi Y. Acute inflammation induces insulin-like growth factor-1 to mediate Bcl-2 and Muc5ac expression in airway epithelial cells. Am J Respir Cell Mol Biol. 2012 Dec; 47(6):784-91. PMID: 22878411.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    72. Sood A, Petersen H, Blanchette CM, Meek P, Picchi MA, Belinsky SA, Tesfaigzi Y. Methylated Genes in Sputum Among Older Smokers With Asthma. Chest. 2012 Aug; 142(2):425-431. PMID: 22345380.
      Citations: 16     Fields:    Translation:HumansCells
    73. Chand HS, Harris JF, Mebratu Y, Chen Y, Wright PS, Randell SH, Tesfaigzi Y. Intracellular insulin-like growth factor-1 induces Bcl-2 expression in airway epithelial cells. J Immunol. 2012 May 01; 188(9):4581-9. PMID: 22461702.
      Citations: 11     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    74. Leng S, Stidley CA, Liu Y, Edlund CK, Willink RP, Han Y, Landi MT, Thun M, Picchi MA, Bruse SE, Crowell RE, Van Den Berg D, Caporaso NE, Amos CI, Siegfried JM, Tesfaigzi Y, Gilliland FD, Belinsky SA. Genetic determinants for promoter hypermethylation in the lungs of smokers: a candidate gene-based study. Cancer Res. 2012 Feb 01; 72(3):707-15. PMID: 22139380.
      Citations: 15     Fields:    Translation:HumansCells
    75. Brehm JM, Hagiwara K, Tesfaigzi Y, Bruse S, Mariani TJ, Bhattacharya S, Boutaoui N, Ziniti JP, Soto-Quiros ME, Avila L, Cho MH, Himes B, Litonjua AA, Jacobson F, Bakke P, Gulsvik A, Anderson WH, Lomas DA, Forno E, Datta S, Silverman EK, Celedón JC. Identification of FGF7 as a novel susceptibility locus for chronic obstructive pulmonary disease. Thorax. 2011 Dec; 66(12):1085-90. PMID: 21921092.
      Citations: 13     Fields:    Translation:Humans
    76. Bruse S, Sood A, Petersen H, Liu Y, Leng S, Celedón JC, Gilliland F, Celli B, Belinsky SA, Tesfaigzi Y. New Mexican Hispanic smokers have lower odds of chronic obstructive pulmonary disease and less decline in lung function than non-Hispanic whites. Am J Respir Crit Care Med. 2011 Dec 01; 184(11):1254-60. PMID: 21908412.
      Citations: 39     Fields:    Translation:Humans
    77. Nyunoya T, March TH, Tesfaigzi Y, Seagrave J. Antioxidant diet protects against emphysema, but increases mortality in cigarette smoke-exposed mice. COPD. 2011 Oct; 8(5):362-8. PMID: 21834692.
      Citations: 11     Fields:    Translation:AnimalsCells
    78. Abraham G, Zizzadoro C, Kacza J, Ellenberger C, Abs V, Franke J, Schoon HA, Seeger J, Tesfaigzi Y, Ungemach FR. Growth and differentiation of primary and passaged equine bronchial epithelial cells under conventional and air-liquid-interface culture conditions. BMC Vet Res. 2011 Jun 07; 7:26. PMID: 21649893.
      Citations: 11     Fields:    Translation:AnimalsCells
    79. Smith KR, Leonard D, McDonald JD, Tesfaigzi Y. Inflammation, mucous cell metaplasia, and Bcl-2 expression in response to inhaled lipopolysaccharide aerosol and effect of rolipram. Toxicol Appl Pharmacol. 2011 Jun 15; 253(3):253-60. PMID: 21504754.
      Citations: 4     Fields:    Translation:AnimalsPHPublic Health
    80. Silverman EK, Vestbo J, Agusti A, Anderson W, Bakke PS, Barnes KC, Barr RG, Bleecker ER, Boezen HM, Burkart KM, Celli BR, Cho MH, Cookson WO, Croxton T, Daley D, DeMeo DL, Gan W, Garcia-Aymerich J, Hall IP, Hansel NN, Hersh CP, Kalsheker N, Kiley JP, Kim WJ, Lambrechts D, Lee SD, Litonjua AA, Lomas DA, London SJ, Nishimura M, Nørdestgaard BG, O'Donnell CJ, Postma DS, Puhan MA, Tesfaigzi Y, Tobin MD, Vogelmeier C, Wilk JB, Wouters E, Young RP, Ziegler-Heitbrock L, MacNee W, Crapo JD. Opportunities and challenges in the genetics of COPD 2010: an International COPD Genetics Conference report. COPD. 2011 Apr; 8(2):121-35. PMID: 21495840.
      Citations: 18     Fields:    Translation:Humans
    81. Mebratu YA, Schwalm K, Smith KR, Schuyler M, Tesfaigzi Y. Cigarette smoke suppresses Bik to cause epithelial cell hyperplasia and mucous cell metaplasia. Am J Respir Crit Care Med. 2011 Jun 01; 183(11):1531-8. PMID: 21317312.
      Citations: 23     Fields:    Translation:HumansAnimalsCells
    82. Belinsky SA, Grimes MJ, Picchi MA, Mitchell HD, Stidley CA, Tesfaigzi Y, Channell MM, Liu Y, Casero RA, Baylin SB, Reed MD, Tellez CS, March TH. Combination therapy with vidaza and entinostat suppresses tumor growth and reprograms the epigenome in an orthotopic lung cancer model. Cancer Res. 2011 Jan 15; 71(2):454-62. PMID: 21224363.
      Citations: 31     Fields:    Translation:HumansAnimalsCells
    83. Sood A, Petersen H, Blanchette CM, Meek P, Picchi MA, Belinsky SA, Tesfaigzi Y. Wood smoke exposure and gene promoter methylation are associated with increased risk for COPD in smokers. Am J Respir Crit Care Med. 2010 Nov 01; 182(9):1098-104. PMID: 20595226.
      Citations: 46     Fields:    Translation:HumansCellsPHPublic Health
    84. Chand HS, Schuyler M, Joste N, Hensler C, Tesfaigzi Y, Masten B, Schrader R, Lipscomb MF. Anti-IgE therapy results in decreased myeloid dendritic cells in asthmatic airways. J Allergy Clin Immunol. 2010 May; 125(5):1157-1158.e5. PMID: 20304471.
      Citations: 2     Fields:    Translation:HumansCells
    85. Hunninghake GM, Cho MH, Tesfaigzi Y, Soto-Quiros ME, Avila L, Lasky-Su J, Stidley C, Melén E, Söderhäll C, Hallberg J, Kull I, Kere J, Svartengren M, Pershagen G, Wickman M, Lange C, Demeo DL, Hersh CP, Klanderman BJ, Raby BA, Sparrow D, Shapiro SD, Silverman EK, Litonjua AA, Weiss ST, Celedón JC. MMP12, lung function, and COPD in high-risk populations. N Engl J Med. 2009 Dec 31; 361(27):2599-608. PMID: 20018959.
      Citations: 121     Fields:    Translation:HumansCellsCTClinical Trials
    86. Pickett G, Seagrave J, Boggs S, Polzin G, Richter P, Tesfaigzi Y. Effects of 10 cigarette smoke condensates on primary human airway epithelial cells by comparative gene and cytokine expression studies. Toxicol Sci. 2010 Mar; 114(1):79-89. PMID: 20015843.
      Citations: 22     Fields:    Translation:HumansCellsPHPublic Health
    87. Mebratu Y, Tesfaigzi Y. How ERK1/2 activation controls cell proliferation and cell death: Is subcellular localization the answer? Cell Cycle. 2009 Apr 15; 8(8):1168-75. PMID: 19282669.
      Citations: 326     Fields:    Translation:HumansAnimalsCells
    88. Mebratu YA, Dickey BF, Evans C, Tesfaigzi Y. The BH3-only protein Bik/Blk/Nbk inhibits nuclear translocation of activated ERK1/2 to mediate IFNgamma-induced cell death. J Cell Biol. 2008 Nov 03; 183(3):429-39. PMID: 18981230.
      Citations: 23     Fields:    Translation:HumansAnimalsCells
    89. Sood A, Stidley CA, Picchi MA, Celedón JC, Gilliland F, Crowell RE, Belinsky SA, Tesfaigzi Y. Difference in airflow obstruction between Hispanic and non-Hispanic White female smokers. COPD. 2008 Oct; 5(5):274-81. PMID: 18972275.
      Citations: 15     Fields:    Translation:Humans
    90. Tesfaigzi Y. Regulation of mucous cell metaplasia in bronchial asthma. Curr Mol Med. 2008 Aug; 8(5):408-15. PMID: 18691068.
      Citations: 12     Fields:    Translation:HumansAnimals
    91. Mishra NC, Rir-Sima-Ah J, Langley RJ, Singh SP, Peña-Philippides JC, Koga T, Razani-Boroujerdi S, Hutt J, Campen M, Kim KC, Tesfaigzi Y, Sopori ML. Nicotine primarily suppresses lung Th2 but not goblet cell and muscle cell responses to allergens. J Immunol. 2008 Jun 01; 180(11):7655-63. PMID: 18490768.
      Citations: 42     Fields:    Translation:AnimalsCells
    92. Wang X, Chen W, Zeng W, Bai L, Tesfaigzi Y, Belinsky SA, Lin Y. Akt-mediated eminent expression of c-FLIP and Mcl-1 confers acquired resistance to TRAIL-induced cytotoxicity to lung cancer cells. Mol Cancer Ther. 2008 May; 7(5):1156-63. PMID: 18483303.
      Citations: 39     Fields:    Translation:HumansCells
    93. Schwalm K, Stevens JF, Jiang Z, Schuyler MR, Schrader R, Randell SH, Green FH, Tesfaigzi Y. Expression of the proapoptotic protein Bax is reduced in bronchial mucous cells of asthmatic subjects. . 2008 Jun; 294(6):L1102-9. PMID: 18390829.
    94. Xiang J, Rir-Sim-Ah J, Tesfaigzi Y. IL-9 and IL-13 induce mucous cell metaplasia that is reduced by IFN-gamma in a Bax-mediated pathway. Am J Respir Cell Mol Biol. 2008 Mar; 38(3):310-7. PMID: 17901408.
      Citations: 10     Fields:    Translation:AnimalsCells
    95. Bredow S, Juri DE, Cardon K, Tesfaigzi Y. Identification of a novel Bcl-2 promoter region that counteracts in a p53-dependent manner the inhibitory P2 region. Gene. 2007 Dec 01; 404(1-2):110-6. PMID: 17913397.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    96. Stout BA, Melendez K, Seagrave J, Holtzman MJ, Wilson B, Xiang J, Tesfaigzi Y. STAT1 activation causes translocation of Bax to the endoplasmic reticulum during the resolution of airway mucous cell hyperplasia by IFN-gamma. J Immunol. 2007 Jun 15; 178(12):8107-16. PMID: 17548649.
      Citations: 18     Fields:    Translation:HumansAnimalsCells
    97. Harris JF, Aden J, Lyons CR, Tesfaigzi Y. Resolution of LPS-induced airway inflammation and goblet cell hyperplasia is independent of IL-18. Respir Res. 2007 Mar 12; 8:24. PMID: 17352829.
      Citations: 12     Fields:    Translation:AnimalsCells
    98. Tesfaigzi Y, Meek P, Lareau S. Exacerbations of chronic obstructive pulmonary disease and chronic mucus hypersecretion. Clin Appl Immunol Rev. 2006 Jan-Feb; 6(1):21-36. PMID: 32288656.
    99. Pierce J, Rir-Sima-Ah J, Estrada I, Wilder J, Strasser A, Tesfaigzi Y. Loss of pro-apoptotic Bim promotes accumulation of pulmonary T lymphocytes and enhances allergen-induced goblet cell metaplasia. . 2006 Nov; 291(5):L862-70. PMID: 16782750.
    100. Adler KB, Shapiro SD, Gallup M, Wu R, Randell SH, Holtzman MJ, Evans CM, Jacoby DB, Tesfaigzi Y, Rose MC, Mossman BT, Prince A, Reddy SP, Davis CW, Matthay MA. Airway epithelium, inflammation, and mechanisms of disease: A tribute to Carol B. Basbaum. Am J Respir Cell Mol Biol. 2006 May; 34(5):523-6. PMID: 16618787.
      Citations:    Fields:    
    101. Bartner LR, Robinson NE, Kiupel M, Tesfaigzi Y. Persistent mucus accumulation: a consequence of delayed bronchial mucous cell apoptosis in RAO-affected horses? . 2006 Oct; 291(4):L602-9. PMID: 16500947.
    102. Tesfaigzi Y. Roles of apoptosis in airway epithelia. Am J Respir Cell Mol Biol. 2006 May; 34(5):537-47. PMID: 16439804.
      Citations: 34     Fields:    Translation:Humans
    103. Tesfaigzi Y, Myers OB, Stidley CA, Schwalm K, Picchi M, Crowell RE, Gilliland FD, Belinsky SA. Genotypes in matrix metalloproteinase 9 are a risk factor for COPD. Int J Chron Obstruct Pulmon Dis. 2006; 1(3):267-78. PMID: 18046864.
      Citations: 12     Fields:    Translation:HumansCells
    104. Tesfaigzi Y, McDonald JD, Reed MD, Singh SP, De Sanctis GT, Eynott PR, Hahn FF, Campen MJ, Mauderly JL. Low-level subchronic exposure to wood smoke exacerbates inflammatory responses in allergic rats. Toxicol Sci. 2005 Dec; 88(2):505-13. PMID: 16162849.
      Citations: 16     Fields:    Translation:AnimalsPHPublic Health
    105. Tesfaigzi Y, Myers OB, Stidley CA, Schwalm K, Picchi M, Crowell RE, Gilliland FD, Belinsky SA. Genotypes in matrix metalloproteinase 9 are risk factors for chronic obstructive pulmonary disease. Exp Lung Res. 2005 Sep; 31 Suppl 1:74-5. PMID: 16395864.
      Citations:    Fields:    Translation:Humans
    106. Harris JF, Fischer MJ, Hotchkiss JR, Monia BP, Randell SH, Harkema JR, Tesfaigzi Y. Bcl-2 sustains increased mucous and epithelial cell numbers in metaplastic airway epithelium. Am J Respir Crit Care Med. 2005 Apr 01; 171(7):764-72. PMID: 15618464.
      Citations: 30     Fields:    Translation:HumansAnimalsCells
    107. Wang SZ, Bao YX, Rosenberger CL, Tesfaigzi Y, Stark JM, Harrod KS. IL-12p40 and IL-18 modulate inflammatory and immune responses to respiratory syncytial virus infection. J Immunol. 2004 Sep 15; 173(6):4040-9. PMID: 15356153.
      Citations: 15     Fields:    Translation:AnimalsCells
    108. Tesfaigzi Y, Harris JF, Hotchkiss JA, Harkema JR. DNA synthesis and Bcl-2 expression during development of mucous cell metaplasia in airway epithelium of rats exposed to LPS. . 2004 Feb; 286(2):L268-74. PMID: 14527929.
    109. Tesfaigzi Y, Wright PS, Belinsky SA. SPRR1B overexpression enhances entry of cells into the G0 phase of the cell cycle. . 2003 Oct; 285(4):L889-98. PMID: 12832281.
    110. Singh SP, Barrett EG, Kalra R, Razani-Boroujerdi S, Langley RJ, Kurup V, Tesfaigzi Y, Sopori ML. Prenatal cigarette smoke decreases lung cAMP and increases airway hyperresponsiveness. Am J Respir Crit Care Med. 2003 Aug 01; 168(3):342-7. PMID: 12791581.
      Citations: 30     Fields:    Translation:AnimalsPHPublic Health
    111. Foster JE, Gott K, Schuyler MR, Kozak W, Tesfaigzi Y. LPS-induced neutrophilic inflammation and Bcl-2 expression in metaplastic mucous cells. . 2003 Aug; 285(2):L405-14. PMID: 12704018.
    112. Tesfaigzi Y. Processes involved in the repair of injured airway epithelia. Arch Immunol Ther Exp (Warsz). 2003; 51(5):283-8. PMID: 14626427.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    113. Scott BR, Walker DM, Tesfaigzi Y, Schöllnberger H, Walker V. Mechanistic basis for nonlinear dose-response relationships for low-dose radiation-induced stochastic effects. Nonlinearity Biol Toxicol Med. 2003 Jan; 1(1):93-122. PMID: 19330114.
    114. Tesfaigzi Y, Fischer MJ, Daheshia M, Green FH, De Sanctis GT, Wilder JA. Bax is crucial for IFN-gamma-induced resolution of allergen-induced mucus cell metaplasia. J Immunol. 2002 Nov 15; 169(10):5919-25. PMID: 12421976.
      Citations: 14     Fields:    Translation:Animals
    115. Henderson RF, Barr EB, Blackwell WB, Clark CR, Conn CA, Kalra R, March TH, Sopori ML, Tesfaigzi Y, Ménache MG, Mash DC. Response of rats to low levels of sarin. Toxicol Appl Pharmacol. 2002 Oct 15; 184(2):67-76. PMID: 12408950.
      Citations: 18     Fields:    Translation:Animals
    116. Gourine AV, Gourine VN, Tesfaigzi Y, Caluwaerts N, Van Leuven F, Kluger MJ. Role of alpha(2)-macroglobulin in fever and cytokine responses induced by lipopolysaccharide in mice. . 2002 Jul; 283(1):R218-26. PMID: 12069948.
    117. Shi ZO, Fischer MJ, De Sanctis GT, Schuyler MR, Tesfaigzi Y. IFN-gamma, but not Fas, mediates reduction of allergen-induced mucous cell metaplasia by inducing apoptosis. J Immunol. 2002 May 01; 168(9):4764-71. PMID: 11971027.
      Citations: 18     Fields:    Translation:HumansAnimalsCells
    118. Tesfaigzi Y, Singh SP, Foster JE, Kubatko J, Barr EB, Fine PM, McDonald JD, Hahn FF, Mauderly JL. Health effects of subchronic exposure to low levels of wood smoke in rats. Toxicol Sci. 2002 Jan; 65(1):115-25. PMID: 11752691.
      Citations: 19     Fields:    Translation:AnimalsCellsPHPublic Health
    119. Tesfaigzi Y. The role of apoptotic regulators in metaplastic mucous cells. Novartis Found Symp. 2002; 248:221-30; discussion 230-6, 277-82. PMID: 12568497.
      Citations:    Fields:    Translation:AnimalsCells
    120. Wang SZ, Rosenberger CL, Espindola TM, Barrett EG, Tesfaigzi Y, Bice DE, Harrod KS. CCSP modulates airway dysfunction and host responses in an Ova-challenged mouse model. . 2001 Nov; 281(5):L1303-11. PMID: 11597923.
    121. Tesfaigzi Y, Rudolph K, Fischer MJ, Conn CA. Bcl-2 mediates sex-specific differences in recovery of mice from LPS-induced signs of sickness independent of IL-6. J Appl Physiol (1985). 2001 Nov; 91(5):2182-9. PMID: 11641360.
      Citations: 8     Fields:    Translation:Animals
    122. Tesfaigzi Y, Kluger M, Kozak W. Clinical and cellular effects of cytochrome P-450 modulators. Respir Physiol. 2001 Oct; 128(1):79-87. PMID: 11535265.
      Citations: 3     Fields:    Translation:HumansAnimals
    123. Henderson RF, Barr EB, Blackwell WB, Clark CR, Conn CA, Kalra R, March TH, Sopori ML, Tesfaigzi Y, Ménache MG, Mash DC, Dokladny K, Kozak W, Kozak A, Wachulec M, Rudolph K, Kluger MJ, Singh SP, Razani-Boroujerdi S, Langley RJ. Response of F344 rats to inhalation of subclinical levels of sarin: exploring potential causes of Gulf War illness. Toxicol Ind Health. 2001 Jun; 17(5-10):294-7. PMID: 12539875.
      Citations: 11     Fields:    Translation:AnimalsPHPublic Health
    124. Wilder JA, Collie DD, Bice DE, Tesfaigzi Y, Lyons CR, Lipscomb MF. Ovalbumin aerosols induce airway hyperreactivity in naïve DO11.10 T cell receptor transgenic mice without pulmonary eosinophilia or OVA-specific antibody. J Leukoc Biol. 2001 Apr; 69(4):538-47. PMID: 11310839.
      Citations: 8     Fields:    Translation:AnimalsPHPublic Health
    125. Gerde P, Muggenburg BA, Lundborg M, Tesfaigzi Y, Dahl AR. Respiratory epithelial penetration and clearance of particle-borne benzo[a]pyrene. Res Rep Health Eff Inst. 2001 Apr; (101):5-25; discussion 27-32. PMID: 11488545.
      Citations: 8     Fields:    Translation:AnimalsCellsPHPublic Health
    126. Tesfaigzi Y, Fischer MJ, Martin AJ, Seagrave J. Bcl-2 in LPS- and allergen-induced hyperplastic mucous cells in airway epithelia of Brown Norway rats. . 2000 Dec; 279(6):L1210-7. PMID: 11076811.
    127. Sun SY, Yue P, Chandraratna RA, Tesfaigzi Y, Hong WK, Lotan R. Dual mechanisms of action of the retinoid CD437: nuclear retinoic acid receptor-mediated suppression of squamous differentiation and receptor-independent induction of apoptosis in UMSCC22B human head and neck squamous cell carcinoma cells. Mol Pharmacol. 2000 Sep; 58(3):508-14. PMID: 10953043.
      Citations: 15     Fields:    Translation:HumansCells
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