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Abel Baerga-Ortíz

InstitutionUniversity of Puerto Rico
AddressUniversity of Puerto Rico - Medical Sciences Campus
Department of Biochemistry
PO Box 365067
San Juan PR 00936-5067
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    Area of Expertise: Long-chain omega-3 fatty acids, colorectal cancer, lung cancer.

    For more information, please visit: http://md.rcm.upr.edu/biochemistry/dt_team/dr-abel-baerga-ortiz/ .

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    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Gómez-Moreno R, Robledo IE, Baerga-Ortiz A. Direct Detection and Quantification of Bacterial Genes Associated with Inflammation in DNA Isolated from Stool. Adv Microbiol. 2014 Nov; 4(15):1065-1075. PMID: 25635239.
    2. Cunci L, Vargas MM, Cunci R, Gomez-Moreno R, Perez I, Baerga-Ortiz A, Gonzalez CI, Cabrera CR. Real-Time Detection of Telomerase Activity in Cancer Cells using a Label-Free Electrochemical Impedimetric Biosensing Microchip. RSC Adv. 2014 Oct 15; 4(94):52357-52365. PMID: 25598969.
    3. Oyola-Robles D, Rullán-Lind C, Carballeira NM, Baerga-Ortiz A. Expression of dehydratase domains from a polyunsaturated fatty acid synthase increases the production of fatty acids in Escherichia coli. Enzyme Microb Technol. 2014 Feb 05; 55:133-9. PMID: 24411456.
      Citations: 3     Fields:    Translation:Cells
    4. Oyola-Robles D, Gay DC, Trujillo U, Sánchez-Parés JM, Bermúdez ML, Rivera-Díaz M, Carballeira NM, Baerga-Ortiz A. Identification of novel protein domains required for the expression of an active dehydratase fragment from a polyunsaturated fatty acid synthase. Protein Sci. 2013 Jul; 22(7):954-63. PMID: 23696301.
      Citations: 2     Fields:    Translation:Cells
    5. Trujillo U, Vázquez-Rosa E, Oyola-Robles D, Stagg LJ, Vassallo DA, Vega IE, Arold ST, Baerga-Ortiz A. Solution structure of the tandem acyl carrier protein domains from a polyunsaturated fatty acid synthase reveals beads-on-a-string configuration. PLoS One. 2013; 8(2):e57859. PMID: 23469090.
      Citations: 7     Fields:    Translation:Cells
    6. Rodríguez-Guilbe M, Oyola-Robles D, Schreiter ER, Baerga-Ortiz A. Structure, activity, and substrate selectivity of the Orf6 thioesterase from Photobacterium profundum. J Biol Chem. 2013 Apr 12; 288(15):10841-8. PMID: 23430744.
      Citations: 5     Fields:    Translation:Cells
    7. Vergnolle O, Hahn F, Baerga-Ortiz A, Leadlay PF, Andexer JN. Stereoselectivity of isolated dehydratase domains of the borrelidin polyketide synthase: implications for cis double bond formation. Chembiochem. 2011 May 02; 12(7):1011-4. PMID: 21472957.
      Citations: 16     Fields:    Translation:Cells
    8. Pastrana-Mena R, Dinglasan RR, Franke-Fayard B, Vega-Rodríguez J, Fuentes-Caraballo M, Baerga-Ortiz A, Coppens I, Jacobs-Lorena M, Janse CJ, Serrano AE. Glutathione reductase-null malaria parasites have normal blood stage growth but arrest during development in the mosquito. J Biol Chem. 2010 Aug 27; 285(35):27045-56. PMID: 20573956.
      Citations: 18     Fields:    Translation:AnimalsCells
    9. Baerga-Ortiz A. Biotechnology and biochemistry of marine natural products. P R Health Sci J. 2009 Sep; 28(3):251-7. PMID: 19715117.
      Citations: 1     Fields:    Translation:Cells
    10. Koeppe JR, Beach MA, Baerga-Ortiz A, Kerns SJ, Komives EA. Mutations in the fourth EGF-like domain affect thrombomodulin-induced changes in the active site of thrombin. Biochemistry. 2008 Oct 14; 47(41):10933-9. PMID: 18803401.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    11. Baerga-Ortiz A, Popovic B, Siskos AP, O'Hare HM, Spiteller D, Williams MG, Campillo N, Spencer JB, Leadlay PF. Directed mutagenesis alters the stereochemistry of catalysis by isolated ketoreductase domains from the erythromycin polyketide synthase. Chem Biol. 2006 Mar; 13(3):277-85. PMID: 16638533.
      Citations: 29     Fields:    Translation:Cells
    12. O'Hare HM, Baerga-Ortiz A, Popovic B, Spencer JB, Leadlay PF. High-throughput mutagenesis to evaluate models of stereochemical control in ketoreductase domains from the erythromycin polyketide synthase. Chem Biol. 2006 Mar; 13(3):287-96. PMID: 16638534.
      Citations: 18     Fields:    Translation:Cells
    13. Siskos AP, Baerga-Ortiz A, Bali S, Stein V, Mamdani H, Spiteller D, Popovic B, Spencer JB, Staunton J, Weissman KJ, Leadlay PF. Molecular basis of Celmer's rules: stereochemistry of catalysis by isolated ketoreductase domains from modular polyketide synthases. Chem Biol. 2005 Oct; 12(10):1145-53. PMID: 16242657.
      Citations: 44     Fields:    Translation:Cells
    14. Mandell JG, Baerga-Ortiz A, Croy CH, Falick AM, Komives EA. Application of amide proton exchange mass spectrometry for the study of protein-protein interactions. Curr Protoc Protein Sci. 2005 Jun; Chapter 20:Unit20.9. PMID: 18429282.
      Citations: 3     Fields:    Translation:Cells
    15. Mandell JG, Baerga-Ortiz A, Falick AM, Komives EA. Measurement of solvent accessibility at protein-protein interfaces. Methods Mol Biol. 2005; 305:65-80. PMID: 15939994.
      Citations: 8     Fields:    Translation:Cells
    16. Baerga-Ortiz A, Bergqvist S, Mandell JG, Komives EA. Two different proteins that compete for binding to thrombin have opposite kinetic and thermodynamic profiles. Protein Sci. 2004 Jan; 13(1):166-76. PMID: 14691232.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    17. Leadlay P, Baerga-Ortiz A. Mammalian fatty acid synthase: closure on a textbook mechanism? Chem Biol. 2003 Feb; 10(2):101-3. PMID: 12618179.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    18. Baerga-Ortiz A, Hughes CA, Mandell JG, Komives EA. Epitope mapping of a monoclonal antibody against human thrombin by H/D-exchange mass spectrometry reveals selection of a diverse sequence in a highly conserved protein. Protein Sci. 2002 Jun; 11(6):1300-8. PMID: 12021429.
      Citations: 35     Fields:    Translation:HumansAnimalsCells
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