My research focuses on the neural circuits of fear regulation, using rodent and human models of fear conditioning, extinction, and active avoidance. My lab uses a variety of experimental techniques including multichannel unit recording, optogenetics, immunocytochemistry, electrical stimulation, and computational modeling. We focus on how the prefrontal cortex influences fear-related activity in the amygdala, thalamus and striatum. This work is applicable to PTSD and OCD, and is funded by the National Institute of Mental Health. My lab has been in Puerto Rico for 18 years and consists of approximately 14 students, post-docs, and technicians, from the U.S., Puerto Rico, and other parts of Latin America. My long-term goal is to promote neuroscience research and training in Latin America.