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John Zhang to Disease Models, Animal

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This is a "connection" page, showing publications John Zhang has written about Disease Models, Animal.
John Zhang
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9.510
Disease Models, Animal
  1. Yan F, Tan X, Wan W, Dixon BJ, Fan R, Enkhjargal B, Li Q, Zhang J, Chen G, Zhang JH. ErbB4 protects against neuronal apoptosis via activation of YAP/PIK3CB signaling pathway in a rat model of subarachnoid hemorrhage. Exp Neurol. 2017 11; 297:92-100.
    View in: PubMed
    Score: 0.411
  2. Lekic T, Rolland W, Manaenko A, Krafft PR, Kamper JE, Suzuki H, Hartman RE, Tang J, Zhang JH. Evaluation of the hematoma consequences, neurobehavioral profiles, and histopathology in a rat model of pontine hemorrhage. J Neurosurg. 2013 Feb; 118(2):465-77.
    View in: PubMed
    Score: 0.298
  3. Krafft PR, Rolland WB, Duris K, Lekic T, Campbell A, Tang J, Zhang JH. Modeling intracerebral hemorrhage in mice: injection of autologous blood or bacterial collagenase. J Vis Exp. 2012 Sep 22; (67):e4289.
    View in: PubMed
    Score: 0.294
  4. Calvert JW, Cahill J, Yamaguchi-Okada M, Zhang JH. Oxygen treatment after experimental hypoxia-ischemia in neonatal rats alters the expression of HIF-1alpha and its downstream target genes. J Appl Physiol (1985). 2006 Sep; 101(3):853-65.
    View in: PubMed
    Score: 0.189
  5. Li Y, Zhou C, Calvert JW, Colohan AR, Zhang JH. Multiple effects of hyperbaric oxygen on the expression of HIF-1 alpha and apoptotic genes in a global ischemia-hypotension rat model. Exp Neurol. 2005 Jan; 191(1):198-210.
    View in: PubMed
    Score: 0.172
  6. Gules I, Satoh M, Clower BR, Nanda A, Zhang JH. Comparison of three rat models of cerebral vasospasm. Am J Physiol Heart Circ Physiol. 2002 Dec; 283(6):H2551-9.
    View in: PubMed
    Score: 0.149
  7. Liu S, Flores JJ, Li B, Deng S, Zuo G, Peng J, Tang J, Zhang JH. IL-20R Activation via rIL-19 Enhances Hematoma Resolution through the IL-20R1/ERK/Nrf2 Pathway in an Experimental GMH Rat Pup Model. Oxid Med Cell Longev. 2021; 2021:5913424.
    View in: PubMed
    Score: 0.131
  8. Hu X, Li S, Doycheva DM, Huang L, Lenahan C, Liu R, Huang J, Gao L, Tang J, Zuo G, Zhang JH. Rh-CSF1 Attenuates Oxidative Stress and Neuronal Apoptosis via the CSF1R/PLCG2/PKA/UCP2 Signaling Pathway in a Rat Model of Neonatal HIE. Oxid Med Cell Longev. 2020; 2020:6801587.
    View in: PubMed
    Score: 0.128
  9. Luo Y, Fang Y, Kang R, Lenahan C, Gamdzyk M, Zhang Z, Okada T, Tang J, Chen S, Zhang JH. Inhibition of EZH2 (Enhancer of Zeste Homolog 2) Attenuates Neuroinflammation via H3k27me3/SOCS3/TRAF6/NF-?B (Trimethylation of Histone 3 Lysine 27/Suppressor of Cytokine Signaling 3/Tumor Necrosis Factor Receptor Family 6/Nuclear Factor-?B) in a Rat Model of Subarachnoid Hemorrhage. Stroke. 2020 11; 51(11):3320-3331.
    View in: PubMed
    Score: 0.128
  10. Yu J, Wang WN, Matei N, Li X, Pang JW, Mo J, Chen SP, Tang JP, Yan M, Zhang JH. Ezetimibe Attenuates Oxidative Stress and Neuroinflammation via the AMPK/Nrf2/TXNIP Pathway after MCAO in Rats. Oxid Med Cell Longev. 2020; 2020:4717258.
    View in: PubMed
    Score: 0.122
  11. Liu SP, Huang L, Flores J, Ding Y, Li P, Peng J, Zuo G, Zhang JH, Lu J, Tang JP. Secukinumab attenuates reactive astrogliosis via IL-17RA/(C/EBP?)/SIRT1 pathway in a rat model of germinal matrix hemorrhage. CNS Neurosci Ther. 2019 10; 25(10):1151-1161.
    View in: PubMed
    Score: 0.116
  12. McBride DW, Gren ECK, Kelln W, Hayes WK, Zhang JH. Crotalus atrox disintegrin reduces hemorrhagic transformation by attenuating matrix metalloproteinase-9 activity after middle cerebral artery occlusion in hyperglycemic male rats. J Neurosci Res. 2020 01; 98(1):191-200.
    View in: PubMed
    Score: 0.111
  13. Zhao L, Chen S, Sherchan P, Ding Y, Zhao W, Guo Z, Yu J, Tang J, Zhang JH. Recombinant CTRP9 administration attenuates neuroinflammation via activating adiponectin receptor 1 after intracerebral hemorrhage in mice. J Neuroinflammation. 2018 Jul 30; 15(1):215.
    View in: PubMed
    Score: 0.110
  14. Zhu Q, Enkhjargal B, Huang L, Zhang T, Sun C, Xie Z, Wu P, Mo J, Tang J, Xie Z, Zhang JH. Aggf1 attenuates neuroinflammation and BBB disruption via PI3K/Akt/NF-?B pathway after subarachnoid hemorrhage in rats. J Neuroinflammation. 2018 Jun 09; 15(1):178.
    View in: PubMed
    Score: 0.109
  15. Gong L, Manaenko A, Fan R, Huang L, Enkhjargal B, McBride D, Ding Y, Tang J, Xiao X, Zhang JH. Osteopontin attenuates inflammation via JAK2/STAT1 pathway in hyperglycemic rats after intracerebral hemorrhage. Neuropharmacology. 2018 08; 138:160-169.
    View in: PubMed
    Score: 0.109
  16. Zhang Y, Ding Y, Lu T, Zhang Y, Xu N, McBride DW, Tang J, Zhang JH. Biliverdin reductase-A attenuated GMH-induced inflammatory response in the spleen by inhibiting toll-like receptor-4 through eNOS/NO pathway. J Neuroinflammation. 2018 Apr 20; 15(1):118.
    View in: PubMed
    Score: 0.108
  17. Chen S, Zhao L, Sherchan P, Ding Y, Yu J, Nowrangi D, Tang J, Xia Y, Zhang JH. Activation of melanocortin receptor 4 with RO27-3225 attenuates neuroinflammation through AMPK/JNK/p38 MAPK pathway after intracerebral hemorrhage in mice. J Neuroinflammation. 2018 Apr 11; 15(1):106.
    View in: PubMed
    Score: 0.108
  18. Xu N, Zhang Y, Doycheva DM, Ding Y, Zhang Y, Tang J, Guo H, Zhang JH. Adiponectin attenuates neuronal apoptosis induced by hypoxia-ischemia via the activation of AdipoR1/APPL1/LKB1/AMPK pathway in neonatal rats. Neuropharmacology. 2018 05 01; 133:415-428.
    View in: PubMed
    Score: 0.107
  19. McBride DW, Wu G, Nowrangi D, Flores JJ, Hui L, Krafft PR, Zhang JH. Delayed Recanalization Promotes Functional Recovery in Rats Following Permanent Middle Cerebral Artery Occlusion. Transl Stroke Res. 2018 04; 9(2):185-198.
    View in: PubMed
    Score: 0.106
  20. Xu X, Wan W, Garza MA, Zhang JQ. Post-myocardial infarction exercise training beneficially regulates thyroid hormone receptor isoforms. J Physiol Sci. 2018 Nov; 68(6):743-748.
    View in: PubMed
    Score: 0.106
  21. Xie Z, Enkhjargal B, Wu L, Zhou K, Sun C, Hu X, Gospodarev V, Tang J, You C, Zhang JH. Exendin-4 attenuates neuronal death via GLP-1R/PI3K/Akt pathway in early brain injury after subarachnoid hemorrhage in rats. Neuropharmacology. 2018 Jan; 128:142-151.
    View in: PubMed
    Score: 0.104
  22. Fan R, Enkhjargal B, Camara R, Yan F, Gong L, Tang J, Chen Y, Zhang JH. Critical role of EphA4 in early brain injury after subarachnoid hemorrhage in rat. Exp Neurol. 2017 10; 296:41-48.
    View in: PubMed
    Score: 0.102
  23. Hu Q, Manaenko A, Bian H, Guo Z, Huang JL, Guo ZN, Yang P, Tang J, Zhang JH. Hyperbaric Oxygen Reduces Infarction Volume and Hemorrhagic Transformation Through ATP/NAD+/Sirt1 Pathway in Hyperglycemic Middle Cerebral Artery Occlusion Rats. Stroke. 2017 06; 48(6):1655-1664.
    View in: PubMed
    Score: 0.101
  24. Krafft PR, McBride D, Rolland WB, Lekic T, Flores JJ, Zhang JH. a7 Nicotinic Acetylcholine Receptor Stimulation Attenuates Neuroinflammation through JAK2-STAT3 Activation in Murine Models of Intracerebral Hemorrhage. Biomed Res Int. 2017; 2017:8134653.
    View in: PubMed
    Score: 0.101
  25. Sherchan P, Huang L, Akyol O, Reis C, Tang J, Zhang JH. Recombinant Slit2 Reduces Surgical Brain Injury Induced Blood Brain Barrier Disruption via Robo4 Dependent Rac1 Activation in a Rodent Model. Sci Rep. 2017 04 07; 7(1):746.
    View in: PubMed
    Score: 0.101
  26. Xie Z, Huang L, Enkhjargal B, Reis C, Wan W, Tang J, Cheng Y, Zhang JH. Intranasal administration of recombinant Netrin-1 attenuates neuronal apoptosis by activating DCC/APPL-1/AKT signaling pathway after subarachnoid hemorrhage in rats. Neuropharmacology. 2017 06; 119:123-133.
    View in: PubMed
    Score: 0.100
  27. Kim CH, McBride DW, Raval R, Sherchan P, Hay KL, Gren EC, Kelln W, Lekic T, Hayes WK, Bull BS, Applegate R, Tang J, Zhang JH. Crotalus atrox venom preconditioning increases plasma fibrinogen and reduces perioperative hemorrhage in a rat model of surgical brain injury. Sci Rep. 2017 01 19; 7:40821.
    View in: PubMed
    Score: 0.099
  28. Shi X, Doycheva DM, Xu L, Tang J, Yan M, Zhang JH. Sestrin2 induced by hypoxia inducible factor1 alpha protects the blood-brain barrier via inhibiting VEGF after severe hypoxic-ischemic injury in neonatal rats. Neurobiol Dis. 2016 Nov; 95:111-21.
    View in: PubMed
    Score: 0.096
  29. Lekic T, Klebe D, Flores J, Peters R, Rolland WB, Tang J, Zhang JH. Remote Ischemic Postconditioning (RIPC) After GMH in Rodents. Acta Neurochir Suppl. 2016; 121:63-7.
    View in: PubMed
    Score: 0.092
  30. McBride DW, Jacob C, Doycheva D, Dixon BJ, Malaguit J, Lekic T, Tang J, Zhang JH. Changes in Brain Swelling and Infarction Volume over Four Days After Hypoxia Ischemia in Neonatal Rats. Acta Neurochir Suppl. 2016; 121:111-4.
    View in: PubMed
    Score: 0.092
  31. Fujii M, Sherchan P, Soejima Y, Doycheva D, Zhao D, Zhang JH. Cannabinoid Receptor Type 2 Agonist Attenuates Acute Neurogenic Pulmonary Edema by Preventing Neutrophil Migration after Subarachnoid Hemorrhage in Rats. Acta Neurochir Suppl. 2016; 121:135-9.
    View in: PubMed
    Score: 0.092
  32. Fujii M, Sherchan P, Soejima Y, Doycheva D, Zhang JH. Subarachnoid Hemorrhage-Triggered Acute Hypotension Is Associated with Left Ventricular Cardiomyocyte Apoptosis in a Rat Model. Acta Neurochir Suppl. 2016; 121:145-50.
    View in: PubMed
    Score: 0.092
  33. Lekic T, Krafft PR, Klebe D, Rolland WB, Flores J, Tang J, Zhang JH. Cyclooxygenase-2 Inhibition Provides Lasting Protection Following Germinal Matrix Hemorrhage in Premature Infant Rats. Acta Neurochir Suppl. 2016; 121:203-7.
    View in: PubMed
    Score: 0.092
  34. McBride DW, Legrand J, Krafft PR, Flores J, Klebe D, Tang J, Zhang JH. Acute Hyperglycemia Is Associated with Immediate Brain Swelling and Hemorrhagic Transformation After Middle Cerebral Artery Occlusion in Rats. Acta Neurochir Suppl. 2016; 121:237-41.
    View in: PubMed
    Score: 0.092
  35. McBride DW, Matei N, C?mara JR, Louis JS, Oudin G, Walker C, Adam L, Liang X, Hu Q, Tang J, Zhang JH. Acute Hyperglycemia Does Not Affect Brain Swelling or Infarction Volume After Middle Cerebral Artery Occlusion in Rats. Acta Neurochir Suppl. 2016; 121:251-5.
    View in: PubMed
    Score: 0.092
  36. Flores JJ, Klebe D, Rolland WB, Lekic T, Krafft PR, Zhang JH. PPAR?-induced upregulation of CD36 enhances hematoma resolution and attenuates long-term neurological deficits after germinal matrix hemorrhage in neonatal rats. Neurobiol Dis. 2016 Mar; 87:124-33.
    View in: PubMed
    Score: 0.092
  37. Huang L, Sherchan P, Wang Y, Reis C, Applegate RL, Tang J, Zhang JH. Phosphoinositide 3-Kinase Gamma Contributes to Neuroinflammation in a Rat Model of Surgical Brain Injury. J Neurosci. 2015 Jul 22; 35(29):10390-401.
    View in: PubMed
    Score: 0.089
  38. McBride DW, Klebe D, Tang J, Zhang JH. Correcting for Brain Swelling's Effects on Infarct Volume Calculation After Middle Cerebral Artery Occlusion in Rats. Transl Stroke Res. 2015 Aug; 6(4):323-38.
    View in: PubMed
    Score: 0.088
  39. Liu F, Chen Y, Hu Q, Li B, Tang J, He Y, Guo Z, Feng H, Tang J, Zhang JH. MFGE8/Integrin ?3 pathway alleviates apoptosis and inflammation in early brain injury after subarachnoid hemorrhage in rats. Exp Neurol. 2015 Oct; 272:120-7.
    View in: PubMed
    Score: 0.088
  40. Zheng Y, Hu Q, Manaenko A, Zhang Y, Peng Y, Xu L, Tang J, Tang J, Zhang JH. 17?-Estradiol attenuates hematoma expansion through estrogen receptor a/silent information regulator 1/nuclear factor-kappa b pathway in hyperglycemic intracerebral hemorrhage mice. Stroke. 2015 Feb; 46(2):485-91.
    View in: PubMed
    Score: 0.086
  41. Liu F, Hu Q, Li B, Manaenko A, Chen Y, Tang J, Guo Z, Tang J, Zhang JH. Recombinant milk fat globule-EGF factor-8 reduces oxidative stress via integrin ?3/nuclear factor erythroid 2-related factor 2/heme oxygenase pathway in subarachnoid hemorrhage rats. Stroke. 2014 Dec; 45(12):3691-7.
    View in: PubMed
    Score: 0.085
  42. Fujii M, Sherchan P, Soejima Y, Hasegawa Y, Flores J, Doycheva D, Zhang JH. Cannabinoid receptor type 2 agonist attenuates apoptosis by activation of phosphorylated CREB-Bcl-2 pathway after subarachnoid hemorrhage in rats. Exp Neurol. 2014 Nov; 261:396-403.
    View in: PubMed
    Score: 0.083
  43. Krafft PR, McBride DW, Lekic T, Rolland WB, Mansell CE, Ma Q, Tang J, Zhang JH. Correlation between subacute sensorimotor deficits and brain edema in two mouse models of intracerebral hemorrhage. Behav Brain Res. 2014 May 01; 264:151-60.
    View in: PubMed
    Score: 0.081
  44. Fathali N, Ostrowski RP, Hasegawa Y, Lekic T, Tang J, Zhang JH. Splenic immune cells in experimental neonatal hypoxia-ischemia. Transl Stroke Res. 2013 Apr; 4(2):208-19.
    View in: PubMed
    Score: 0.076
  45. Soejima Y, Hu Q, Krafft PR, Fujii M, Tang J, Zhang JH. Hyperbaric oxygen preconditioning attenuates hyperglycemia-enhanced hemorrhagic transformation by inhibiting matrix metalloproteinases in focal cerebral ischemia in rats. Exp Neurol. 2013 Sep; 247:737-43.
    View in: PubMed
    Score: 0.076
  46. Ayer RE, Ostrowski RP, Sugawara T, Ma Q, Jafarian N, Tang J, Zhang JH. Statin-induced T-lymphocyte modulation and neuroprotection following experimental subarachnoid hemorrhage. Acta Neurochir Suppl. 2013; 115:259-66.
    View in: PubMed
    Score: 0.075
  47. Rolland WB, Lekic T, Krafft PR, Hasegawa Y, Altay O, Hartman R, Ostrowski R, Manaenko A, Tang J, Zhang JH. Fingolimod reduces cerebral lymphocyte infiltration in experimental models of rodent intracerebral hemorrhage. Exp Neurol. 2013 Mar; 241:45-55.
    View in: PubMed
    Score: 0.075
  48. Mu J, Ostrowski RP, Soejima Y, Rolland WB, Krafft PR, Tang J, Zhang JH. Delayed hyperbaric oxygen therapy induces cell proliferation through stabilization of cAMP responsive element binding protein in the rat model of MCAo-induced ischemic brain injury. Neurobiol Dis. 2013 Mar; 51:133-43.
    View in: PubMed
    Score: 0.074
  49. Benggon M, Chen H, Applegate R, Martin R, Zhang JH. Effect of dexmedetomidine on brain edema and neurological outcomes in surgical brain injury in rats. Anesth Analg. 2012 Jul; 115(1):154-9.
    View in: PubMed
    Score: 0.072
  50. Lekic T, Manaenko A, Rolland W, Krafft PR, Peters R, Hartman RE, Altay O, Tang J, Zhang JH. Rodent neonatal germinal matrix hemorrhage mimics the human brain injury, neurological consequences, and post-hemorrhagic hydrocephalus. Exp Neurol. 2012 Jul; 236(1):69-78.
    View in: PubMed
    Score: 0.071
  51. Hasegawa Y, Suzuki H, Sherchan P, Zhan Y, Duris K, Zhang JH. Tyrosine phosphatase inhibition attenuates early brain injury after subarachnoid hemorrhage in rats. Acta Neurochir Suppl. 2011; 110(Pt 1):67-70.
    View in: PubMed
    Score: 0.065
  52. Guo ZD, Wu HT, Sun XC, Zhang XD, Zhang JH. Protection of minocycline on early brain injury after subarachnoid hemorrhage in rats. Acta Neurochir Suppl. 2011; 110(Pt 1):71-4.
    View in: PubMed
    Score: 0.065
  53. Suzuki H, Ayer R, Sugawara T, Chen W, Sozen T, Hasegawa Y, Kanamaru K, Zhang JH. Role of osteopontin in early brain injury after subarachnoid hemorrhage in rats. Acta Neurochir Suppl. 2011; 110(Pt 1):75-9.
    View in: PubMed
    Score: 0.065
  54. Guo ZD, Zhang XD, Wu HT, Lin B, Sun XC, Zhang JH. Matrix metalloproteinase 9 inhibition reduces early brain injury in cortex after subarachnoid hemorrhage. Acta Neurochir Suppl. 2011; 110(Pt 1):81-4.
    View in: PubMed
    Score: 0.065
  55. He Z, Sun X, Guo Z, Zhang JH. Expression and role of COMT in a rat subarachnoid hemorrhage model. Acta Neurochir Suppl. 2011; 110(Pt 1):181-7.
    View in: PubMed
    Score: 0.065
  56. Suzuki H, Hasegawa Y, Kanamaru K, Zhang JH. Effect of recombinant osteopontin on cerebral vasospasm after subarachnoid hemorrhage in rats. Acta Neurochir Suppl. 2011; 110(Pt 2):29-32.
    View in: PubMed
    Score: 0.065
  57. Lekic T, Ostrowski RP, Suzuki H, Manaenko A, Rolland W, Fathali N, Tang J, Zhang JH. The postpartum period of pregnancy worsens brain injury and functional outcome after cerebellar hemorrhage in rats. Acta Neurochir Suppl. 2011; 111:37-41.
    View in: PubMed
    Score: 0.065
  58. Lekic T, Manaenko A, Rolland W, Tang J, Zhang JH. A novel preclinical model of germinal matrix hemorrhage using neonatal rats. Acta Neurochir Suppl. 2011; 111:55-60.
    View in: PubMed
    Score: 0.065
  59. Rolland WB, Manaenko A, Lekic T, Hasegawa Y, Ostrowski R, Tang J, Zhang JH. FTY720 is neuroprotective and improves functional outcomes after intracerebral hemorrhage in mice. Acta Neurochir Suppl. 2011; 111:213-7.
    View in: PubMed
    Score: 0.065
  60. Khatibi NH, Jadhav V, Charles S, Chiu J, Buchholz J, Tang J, Zhang JH. Capsaicin pre-treatment provides neurovascular protection against neonatal hypoxic-ischemic brain injury in rats. Acta Neurochir Suppl. 2011; 111:225-30.
    View in: PubMed
    Score: 0.065
  61. Suzuki H, Hasegawa Y, Ayer R, Sugawara T, Chen W, Sozen T, Kanamaru K, Taki W, Zhang JH. Effects of recombinant osteopontin on blood-brain barrier disruption after subarachnoid hemorrhage in rats. Acta Neurochir Suppl. 2011; 111:231-6.
    View in: PubMed
    Score: 0.065
  62. Lekic T, Manaenko A, Rolland W, Fathali N, Peterson M, Tang J, Zhang JH. Protective effect of hydrogen gas therapy after germinal matrix hemorrhage in neonatal rats. Acta Neurochir Suppl. 2011; 111:237-41.
    View in: PubMed
    Score: 0.065
  63. Lekic T, Manaenko A, Rolland W, Ostrowski RP, Virbel K, Tang J, Zhang JH. Beneficial effect of hyperbaric oxygenation after neonatal germinal matrix hemorrhage. Acta Neurochir Suppl. 2011; 111:253-7.
    View in: PubMed
    Score: 0.065
  64. Lekic T, Rolland W, Hartman R, Kamper J, Suzuki H, Tang J, Zhang JH. Characterization of the brain injury, neurobehavioral profiles, and histopathology in a rat model of cerebellar hemorrhage. Exp Neurol. 2011 Jan; 227(1):96-103.
    View in: PubMed
    Score: 0.064
  65. Xu X, Zhao W, Wan W, Ji LL, Powers AS, Erikson JM, Zhang JQ. Exercise training combined with angiotensin II receptor blockade reduces oxidative stress after myocardial infarction in rats. Exp Physiol. 2010 Oct; 95(10):1008-15.
    View in: PubMed
    Score: 0.063
  66. Chen C, Ostrowski RP, Zhou C, Tang J, Zhang JH. Suppression of hypoxia-inducible factor-1alpha and its downstream genes reduces acute hyperglycemia-enhanced hemorrhagic transformation in a rat model of cerebral ischemia. J Neurosci Res. 2010 Jul; 88(9):2046-55.
    View in: PubMed
    Score: 0.063
  67. Lekic T, Hartman R, Rojas H, Manaenko A, Chen W, Ayer R, Tang J, Zhang JH. Protective effect of melatonin upon neuropathology, striatal function, and memory ability after intracerebral hemorrhage in rats. J Neurotrauma. 2010 Mar; 27(3):627-37.
    View in: PubMed
    Score: 0.061
  68. Suzuki H, Ayer R, Sugawara T, Chen W, Sozen T, Hasegawa Y, Kanamaru K, Zhang JH. Protective effects of recombinant osteopontin on early brain injury after subarachnoid hemorrhage in rats. Crit Care Med. 2010 Feb; 38(2):612-8.
    View in: PubMed
    Score: 0.061
  69. Ostrowski RP, Jadhav V, Chen W, Zhang JH. Reduced matrix metalloproteinase-9 activity and cell death after global ischemia in the brain preconditioned with hyperbaric oxygen. Acta Neurochir Suppl. 2010; 106:47-9.
    View in: PubMed
    Score: 0.061
  70. Ayer R, Chen W, Sugawara T, Suzuki H, Zhang JH. Role of gap junctions in early brain injury following subarachnoid hemorrhage. Brain Res. 2010 Feb 22; 1315:150-8.
    View in: PubMed
    Score: 0.061
  71. Chen W, Hartman R, Ayer R, Marcantonio S, Kamper J, Tang J, Zhang JH. Matrix metalloproteinases inhibition provides neuroprotection against hypoxia-ischemia in the developing brain. J Neurochem. 2009 Nov; 111(3):726-36.
    View in: PubMed
    Score: 0.059
  72. Jadhav V, Ostrowski RP, Tong W, Matus B, Jesunathadas R, Zhang JH. Cyclo-oxygenase-2 mediates hyperbaric oxygen preconditioning-induced neuroprotection in the mouse model of surgical brain injury. Stroke. 2009 Sep; 40(9):3139-42.
    View in: PubMed
    Score: 0.059
  73. Solaroglu I, Cahill J, Tsubokawa T, Beskonakli E, Zhang JH. Granulocyte colony-stimulating factor protects the brain against experimental stroke via inhibition of apoptosis and inflammation. Neurol Res. 2009 Mar; 31(2):167-72.
    View in: PubMed
    Score: 0.057
  74. Sugawara T, Jadhav V, Ayer R, Chen W, Suzuki H, Zhang JH. Thrombin inhibition by argatroban ameliorates early brain injury and improves neurological outcomes after experimental subarachnoid hemorrhage in rats. Stroke. 2009 Apr; 40(4):1530-2.
    View in: PubMed
    Score: 0.057
  75. Matchett GA, Fathali N, Hasegawa Y, Jadhav V, Ostrowski RP, Martin RD, Dorotta IR, Sun X, Zhang JH. Hydrogen gas is ineffective in moderate and severe neonatal hypoxia-ischemia rat models. Brain Res. 2009 Mar 09; 1259:90-7.
    View in: PubMed
    Score: 0.057
  76. Wang L, Li W, Kang Z, Liu Y, Deng X, Tao H, Xu W, Li R, Sun X, Zhang JH. Hyperbaric oxygen preconditioning attenuates early apoptosis after spinal cord ischemia in rats. J Neurotrauma. 2009 Jan; 26(1):55-66.
    View in: PubMed
    Score: 0.057
  77. Sugawara T, Ayer R, Jadhav V, Chen W, Tsubokawa T, Zhang JH. Simvastatin attenuation of cerebral vasospasm after subarachnoid hemorrhage in rats via increased phosphorylation of Akt and endothelial nitric oxide synthase. J Neurosci Res. 2008 Dec; 86(16):3635-43.
    View in: PubMed
    Score: 0.056
  78. Ayer RE, Sugawara T, Chen W, Tong W, Zhang JH. Melatonin decreases mortality following severe subarachnoid hemorrhage. J Pineal Res. 2008 Mar; 44(2):197-204.
    View in: PubMed
    Score: 0.054
  79. Xu X, Wan W, Ji L, Lao S, Powers AS, Zhao W, Erikson JM, Zhang JQ. Exercise training combined with angiotensin II receptor blockade limits post-infarct ventricular remodelling in rats. Cardiovasc Res. 2008 Jun 01; 78(3):523-32.
    View in: PubMed
    Score: 0.053
  80. Ayer RE, Sugawara T, Zhang JH. Effects of melatonin in early brain injury following subarachnoid hemorrhage. Acta Neurochir Suppl. 2008; 102:327-30.
    View in: PubMed
    Score: 0.053
  81. Jadhav V, Yamaguchi M, Obenaus A, Zhang JH. Matrix metalloproteinase inhibition attenuates brain edema after surgical brain injury. Acta Neurochir Suppl. 2008; 102:357-61.
    View in: PubMed
    Score: 0.053
  82. Chen W, Jadhav V, Tang J, Zhang JH. HIF-1 alpha inhibition ameliorates neonatal brain damage after hypoxic-ischemic injury. Acta Neurochir Suppl. 2008; 102:395-9.
    View in: PubMed
    Score: 0.053
  83. Wan W, Powers AS, Li J, Ji L, Erikson JM, Zhang JQ. Effect of post-myocardial infarction exercise training on the renin-angiotensin-aldosterone system and cardiac function. Am J Med Sci. 2007 Oct; 334(4):265-73.
    View in: PubMed
    Score: 0.052
  84. Zhou D, Matchett GA, Jadhav V, Dach N, Zhang JH. The effect of 2-methoxyestradiol, a HIF-1 alpha inhibitor, in global cerebral ischemia in rats. Neurol Res. 2008 Apr; 30(3):268-71.
    View in: PubMed
    Score: 0.052
  85. Sugawara T, Ayer R, Jadhav V, Zhang JH. A new grading system evaluating bleeding scale in filament perforation subarachnoid hemorrhage rat model. J Neurosci Methods. 2008 Jan 30; 167(2):327-34.
    View in: PubMed
    Score: 0.052
  86. Ostrowski RP, Graupner G, Titova E, Zhang J, Chiu J, Dach N, Corleone D, Tang J, Zhang JH. The hyperbaric oxygen preconditioning-induced brain protection is mediated by a reduction of early apoptosis after transient global cerebral ischemia. Neurobiol Dis. 2008 Jan; 29(1):1-13.
    View in: PubMed
    Score: 0.051
  87. Huang ZX, Kang ZM, Gu GJ, Peng GN, Yun L, Tao HY, Xu WG, Sun XJ, Zhang JH. Therapeutic effects of hyperbaric oxygen in a rat model of endothelin-1-induced focal cerebral ischemia. Brain Res. 2007 Jun 11; 1153:204-13.
    View in: PubMed
    Score: 0.050
  88. Matchett GA, Calinisan JB, Matchett GC, Martin RD, Zhang JH. The effect of granulocyte-colony stimulating factor in global cerebral ischemia in rats. Brain Res. 2007 Mar 09; 1136(1):200-7.
    View in: PubMed
    Score: 0.049
  89. Jadhav V, Solaroglu I, Obenaus A, Zhang JH. Neuroprotection against surgically induced brain injury. Surg Neurol. 2007 Jan; 67(1):15-20; discussion 20.
    View in: PubMed
    Score: 0.049
  90. Ostrowski RP, Tang J, Zhang JH. Hyperbaric oxygen suppresses NADPH oxidase in a rat subarachnoid hemorrhage model. Stroke. 2006 May; 37(5):1314-8.
    View in: PubMed
    Score: 0.047
  91. Ostrowski RP, Colohan AR, Zhang JH. Mechanisms of hyperbaric oxygen-induced neuroprotection in a rat model of subarachnoid hemorrhage. J Cereb Blood Flow Metab. 2005 May; 25(5):554-71.
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    Score: 0.044
  92. Yin D, Zhang JH. Delayed and multiple hyperbaric oxygen treatments expand therapeutic window in rat focal cerebral ischemic model. Neurocrit Care. 2005; 2(2):206-11.
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    Score: 0.043
  93. Tang J, Liu J, Zhou C, Alexander JS, Nanda A, Granger DN, Zhang JH. Mmp-9 deficiency enhances collagenase-induced intracerebral hemorrhage and brain injury in mutant mice. J Cereb Blood Flow Metab. 2004 Oct; 24(10):1133-45.
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    Score: 0.042
  94. Calvert JW, Zhou C, Zhang JH. Transient exposure of rat pups to hyperoxia at normobaric and hyperbaric pressures does not cause retinopathy of prematurity. Exp Neurol. 2004 Sep; 189(1):150-61.
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    Score: 0.042
  95. Kusaka G, Calvert JW, Smelley C, Nanda A, Zhang JH. New lumbar method for monitoring cerebrospinal fluid pressure in rats. J Neurosci Methods. 2004 May 30; 135(1-2):121-7.
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    Score: 0.041
  96. Sun Y, Zhou C, Polk P, Nanda A, Zhang JH. Mechanisms of erythropoietin-induced brain protection in neonatal hypoxia-ischemia rat model. J Cereb Blood Flow Metab. 2004 Feb; 24(2):259-70.
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    Score: 0.040
  97. Calvert JW, Zhou C, Nanda A, Zhang JH. Effect of hyperbaric oxygen on apoptosis in neonatal hypoxia-ischemia rat model. J Appl Physiol (1985). 2003 Nov; 95(5):2072-80.
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    Score: 0.040
  98. Sun C, Rahman MSU, Enkhjargal B, Peng J, Zhou K, Xie Z, Wu L, Zhang T, Zhu Q, Tang J, Zeng Y, Zhang JH, Xu S. Osteopontin modulates microglial activation states and attenuates inflammatory responses after subarachnoid hemorrhage in rats. Exp Neurol. 2024 01; 371:114585.
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    Score: 0.040
  99. Kusaka G, Kimura H, Kusaka I, Perkins E, Nanda A, Zhang JH. Contribution of Src tyrosine kinase to cerebral vasospasm after subarachnoid hemorrhage. J Neurosurg. 2003 Aug; 99(2):383-90.
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    Score: 0.039
  100. Yin D, Zhou C, Kusaka I, Calvert JW, Parent AD, Nanda A, Zhang JH. Inhibition of apoptosis by hyperbaric oxygen in a rat focal cerebral ischemic model. J Cereb Blood Flow Metab. 2003 Jul; 23(7):855-64.
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    Score: 0.039
  101. Deng S, Jin P, Liu S, He Y, Sherchan P, Zhang JH, Gong Y, Tang J. Recruitment of regulatory T cells with rCCL17 promotes M2 microglia/macrophage polarization through TGF?/TGF?R/Smad2/3 pathway in a mouse model of intracerebral hemorrhage. Exp Neurol. 2023 09; 367:114451.
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    Score: 0.038
  102. Calvert JW, Yin W, Patel M, Badr A, Mychaskiw G, Parent AD, Zhang JH. Hyperbaric oxygenation prevented brain injury induced by hypoxia-ischemia in a neonatal rat model. Brain Res. 2002 Sep 27; 951(1):1-8.
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    Score: 0.037
  103. Pang J, Matei N, Peng J, Zheng W, Yu J, Luo X, Camara R, Chen L, Tang J, Zhang JH, Jiang Y. Macrophage Infiltration Reduces Neurodegeneration and Improves Stroke Recovery after Delayed Recanalization in Rats. Oxid Med Cell Longev. 2022; 2022:6422202.
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    Score: 0.036
  104. Satoh M, Parent AD, Zhang JH. Inhibitory effect with antisense mitogen-activated protein kinase oligodeoxynucleotide against cerebral vasospasm in rats. Stroke. 2002 Mar; 33(3):775-81.
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    Score: 0.035
  105. Yin W, Badr AE, Mychaskiw G, Zhang JH. Down regulation of COX-2 is involved in hyperbaric oxygen treatment in a rat transient focal cerebral ischemia model. Brain Res. 2002 Feb 01; 926(1-2):165-71.
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    Score: 0.035
  106. Li P, Zhao G, Chen F, Ding Y, Wang T, Liu S, Lu W, Xu W, Flores J, Ocak U, Zhang T, Zhang JH, Tang J. Rh-relaxin-2 attenuates degranulation of mast cells by inhibiting NF-?B through PI3K-AKT/TNFAIP3 pathway in an experimental germinal matrix hemorrhage rat model. J Neuroinflammation. 2020 Aug 28; 17(1):250.
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    Score: 0.032
  107. Cejka C, Kossl J, Holan V, Zhang JH, Cejkova J. An Immunohistochemical Study of the Increase in Antioxidant Capacity of Corneal Epithelial Cells by Molecular Hydrogen, Leading to the Suppression of Alkali-Induced Oxidative Stress. Oxid Med Cell Longev. 2020; 2020:7435260.
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    Score: 0.031
  108. Wang J, Zuo Y, Zhuang K, Luo K, Yan X, Li J, Zhang JH, Liu F. Recombinant Human Milk Fat Globule-Epidermal Growth Factor 8 Attenuates Microthrombosis after Subarachnoid Hemorrhage in Rats. J Stroke Cerebrovasc Dis. 2020 Mar; 29(3):104536.
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    Score: 0.030
  109. Li P, Zhao G, Ding Y, Wang T, Flores J, Ocak U, Wu P, Zhang T, Mo J, Zhang JH, Tang J. Rh-IFN-a attenuates neuroinflammation and improves neurological function by inhibiting NF-?B through JAK1-STAT1/TRAF3 pathway in an experimental GMH rat model. Brain Behav Immun. 2019 07; 79:174-185.
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    Score: 0.029
  110. Pang J, Peng J, Matei N, Yang P, Kuai L, Wu Y, Chen L, Vitek MP, Li F, Sun X, Zhang JH, Jiang Y. Apolipoprotein E Exerts a Whole-Brain Protective Property by Promoting M1? Microglia Quiescence After Experimental Subarachnoid Hemorrhage in Mice. Transl Stroke Res. 2018 12; 9(6):654-668.
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    Score: 0.028
  111. McBride DW, Reis C, Zhang JH, Applegate R, Tang J. Remote Limb Ischemic Preconditioning Attenuates Cerebrovascular Depression During Sinusoidal Galvanic Vestibular Stimulation via a1-Adrenoceptor-Protein Kinase Ce-Endothelial NO Synthase Pathway in Rats. J Am Heart Assoc. 2018 03 24; 7(7).
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    Score: 0.027
  112. Wan W, Ding Y, Xie Z, Li Q, Yan F, Budbazar E, Pearce WJ, Hartman R, Obenaus A, Zhang JH, Jiang Y, Tang J. PDGFR-? modulates vascular smooth muscle cell phenotype via IRF-9/SIRT-1/NF-?B pathway in subarachnoid hemorrhage rats. J Cereb Blood Flow Metab. 2019 07; 39(7):1369-1380.
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    Score: 0.027
  113. Ye L, Feng Z, Doycheva D, Malaguit J, Dixon B, Xu N, Zhang JH, Tang J. CpG-ODN exerts a neuroprotective effect via the TLR9/pAMPK signaling pathway by activation of autophagy in a neonatal HIE rat model. Exp Neurol. 2018 03; 301(Pt A):70-80.
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    Score: 0.026
  114. Akyol GY, Manaenko A, Akyol O, Solaroglu I, Ho WM, Ding Y, Flores J, Zhang JH, Tang J. IVIG activates Fc?RIIB-SHIP1-PIP3 Pathway to stabilize mast cells and suppress inflammation after ICH in mice. Sci Rep. 2017 Nov 14; 7(1):15583.
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    Score: 0.026
  115. Bosetti F, Koenig JI, Ayata C, Back SA, Becker K, Broderick JP, Carmichael ST, Cho S, Cipolla MJ, Corbett D, Corriveau RA, Cramer SC, Ferguson AR, Finklestein SP, Ford BD, Furie KL, Hemmen TM, Iadecola C, Jakeman LB, Janis S, Jauch EC, Johnston KC, Kochanek PM, Kohn H, Lo EH, Lyden PD, Mallard C, McCullough LD, McGavern LM, Meschia JF, Moy CS, Perez-Pinzon MA, Ramadan I, Savitz SI, Schwamm LH, Steinberg GK, Stenzel-Poore MP, Tymianski M, Warach S, Wechsler LR, Zhang JH, Koroshetz W. Translational Stroke Research: Vision and Opportunities. Stroke. 2017 09; 48(9):2632-2637.
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    Score: 0.026
  116. Obenaus A, Ng M, Orantes AM, Kinney-Lang E, Rashid F, Hamer M, DeFazio RA, Tang J, Zhang JH, Pearce WJ. Traumatic brain injury results in acute rarefication of the vascular network. Sci Rep. 2017 03 22; 7(1):239.
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    Score: 0.025
  117. Yang P, Manaenko A, Xu F, Miao L, Wang G, Hu X, Guo ZN, Hu Q, Hartman RE, Pearce WJ, Obenaus A, Zhang JH, Chen G, Tang J. Role of PDGF-D and PDGFR-? in neuroinflammation in experimental ICH mice model. Exp Neurol. 2016 09; 283(Pt A):157-64.
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    Score: 0.024
  118. Li Q, Chen Y, Li B, Luo C, Zuo S, Liu X, Zhang JH, Ruan H, Feng H. Hemoglobin induced NO/cGMP suppression Deteriorate Microcirculation via Pericyte Phenotype Transformation after Subarachnoid Hemorrhage in Rats. Sci Rep. 2016 Feb 25; 6:22070.
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    Score: 0.023
  119. Yan H, Chen Y, Li L, Jiang J, Wu G, Zuo Y, Zhang JH, Feng H, Yan X, Liu F. Decorin alleviated chronic hydrocephalus via inhibiting TGF-?1/Smad/CTGF pathway after subarachnoid hemorrhage in rats. Brain Res. 2016 Jan 01; 1630:241-53.
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    Score: 0.023
  120. Chen Q, Tang J, Tan L, Guo J, Tao Y, Li L, Chen Y, Liu X, Zhang JH, Chen Z, Feng H. Intracerebral Hematoma Contributes to Hydrocephalus After Intraventricular Hemorrhage via Aggravating Iron Accumulation. Stroke. 2015 Oct; 46(10):2902-8.
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    Score: 0.022
  121. Iniaghe LO, Krafft PR, Klebe DW, Omogbai EKI, Zhang JH, Tang J. Dimethyl fumarate confers neuroprotection by casein kinase 2 phosphorylation of Nrf2 in murine intracerebral hemorrhage. Neurobiol Dis. 2015 Oct; 82:349-358.
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    Score: 0.022
  122. Li L, Klebe D, Doycheva D, McBride DW, Krafft PR, Flores J, Zhou C, Zhang JH, Tang J. G-CSF ameliorates neuronal apoptosis through GSK-3? inhibition in neonatal hypoxia-ischemia in rats. Exp Neurol. 2015 Jan; 263:141-9.
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    Score: 0.021
  123. Doycheva DM, Hadley T, Li L, Applegate RL, Zhang JH, Tang J. Anti-neutrophil antibody enhances the neuroprotective effects of G-CSF by decreasing number of neutrophils in hypoxic ischemic neonatal rat model. Neurobiol Dis. 2014 Sep; 69:192-9.
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    Score: 0.021
  124. Yang Z, Zhao T, Zou Y, Zhang JH, Feng H. Curcumin inhibits microglia inflammation and confers neuroprotection in intracerebral hemorrhage. Immunol Lett. 2014 Jul; 160(1):89-95.
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    Score: 0.020
  125. Manaenko A, Lekic T, Ma Q, Zhang JH, Tang J. Hydrogen inhalation ameliorated mast cell-mediated brain injury after intracerebral hemorrhage in mice. Crit Care Med. 2013 May; 41(5):1266-75.
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    Score: 0.019
  126. Huang L, Zhao S, Zhang JH, Sun X. Hydrogen saline treatment attenuates hyperoxia-induced retinopathy by inhibition of oxidative stress and reduction of VEGF expression. Ophthalmic Res. 2012; 47(3):122-7.
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    Score: 0.017
  127. Ma Q, Huang B, Khatibi N, Rolland W, Suzuki H, Zhang JH, Tang J. PDGFR-a inhibition preserves blood-brain barrier after intracerebral hemorrhage. Ann Neurol. 2011 Dec; 70(6):920-31.
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    Score: 0.017
  128. Titova E, Ostrowski RP, Adami A, Badaut J, Lalas S, Ghosh N, Vlkolinsky R, Zhang JH, Obenaus A. Brain irradiation improves focal cerebral ischemia recovery in aged rats. J Neurol Sci. 2011 Jul 15; 306(1-2):143-53.
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    Score: 0.017
  129. Wang C, Li J, Liu Q, Yang R, Zhang JH, Cao YP, Sun XJ. Hydrogen-rich saline reduces oxidative stress and inflammation by inhibit of JNK and NF-?B activation in a rat model of amyloid-beta-induced Alzheimer's disease. Neurosci Lett. 2011 Mar 17; 491(2):127-32.
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    Score: 0.016
  130. Manaenko A, Lekic T, Zhang JH, Tang J. NC1900, an arginine vasopressin analogue, fails to reduce brain edema and improve neurobehavioral deficits in an intracerebral hemorrhagic stroke mice model. Acta Neurochir Suppl. 2011; 111:155-9.
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    Score: 0.016
  131. Manaenko A, Fathali N, Williams S, Lekic T, Zhang JH, Tang J. Geldanamycin reduced brain injury in mouse model of intracerebral hemorrhage. Acta Neurochir Suppl. 2011; 111:161-5.
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    Score: 0.016
  132. Manaenko A, Lekic T, Ma Q, Ostrowski RP, Zhang JH, Tang J. Hydrogen inhalation is neuroprotective and improves functional outcomes in mice after intracerebral hemorrhage. Acta Neurochir Suppl. 2011; 111:179-83.
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    Score: 0.016
  133. Hu Q, Chen C, Khatibi NH, Li L, Yang L, Wang K, Han J, Duan W, Zhang JH, Zhou C. Lentivirus-mediated transfer of MMP-9 shRNA provides neuroprotection following focal ischemic brain injury in rats. Brain Res. 2011 Jan 07; 1367:347-59.
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    Score: 0.016
  134. Fathali N, Lekic T, Zhang JH, Tang J. Long-term evaluation of granulocyte-colony stimulating factor on hypoxic-ischemic brain damage in infant rats. Intensive Care Med. 2010 Sep; 36(9):1602-8.
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    Score: 0.016
  135. Ping Z, Liu W, Kang Z, Cai J, Wang Q, Cheng N, Wang S, Wang S, Zhang JH, Sun X. Sulforaphane protects brains against hypoxic-ischemic injury through induction of Nrf2-dependent phase 2 enzyme. Brain Res. 2010 Jul 09; 1343:178-85.
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    Score: 0.016
  136. Li J, Wang C, Zhang JH, Cai JM, Cao YP, Sun XJ. Hydrogen-rich saline improves memory function in a rat model of amyloid-beta-induced Alzheimer's disease by reduction of oxidative stress. Brain Res. 2010 Apr 30; 1328:152-61.
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    Score: 0.015
  137. Manaenko A, Lekic T, Sozen T, Tsuchiyama R, Zhang JH, Tang J. Effect of gap junction inhibition on intracerebral hemorrhage-induced brain injury in mice. Neurol Res. 2009 Mar; 31(2):173-8.
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    Score: 0.014
  138. Xu J, Peng Z, Li R, Dou T, Xu W, Gu G, Liu Y, Kang Z, Tao H, Zhang JH, Ostrowski RP, Lu J, Sun X. Normoxic induction of cerebral HIF-1alpha by acetazolamide in rats: role of acidosis. Neurosci Lett. 2009 Feb 27; 451(3):274-8.
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    Score: 0.014
  139. Hu Q, Chen C, Yan J, Yang X, Shi X, Zhao J, Lei J, Yang L, Wang K, Chen L, Huang H, Han J, Zhang JH, Zhou C. Therapeutic application of gene silencing MMP-9 in a middle cerebral artery occlusion-induced focal ischemia rat model. Exp Neurol. 2009 Mar; 216(1):35-46.
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    Score: 0.014
  140. Tang WH, Chen Z, Liu Z, Zhang JH, Xi G, Feng H. The effect of ecdysterone on cerebral vasospasm following experimental subarachnoid hemorrhage in vitro and in vivo. Neurol Res. 2008 Jul; 30(6):571-80.
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    Score: 0.014
  141. Cai J, Kang Z, Liu WW, Luo X, Qiang S, Zhang JH, Ohta S, Sun X, Xu W, Tao H, Li R. Hydrogen therapy reduces apoptosis in neonatal hypoxia-ischemia rat model. Neurosci Lett. 2008 Aug 22; 441(2):167-72.
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    Score: 0.014
  142. Hyong A, Jadhav V, Lee S, Tong W, Rowe J, Zhang JH, Tang J. Rosiglitazone, a PPAR gamma agonist, attenuates inflammation after surgical brain injury in rodents. Brain Res. 2008 Jun 18; 1215:218-24.
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    Score: 0.014
  143. Titova E, Ostrowski RP, Sowers LC, Zhang JH, Tang J. Effects of apocynin and ethanol on intracerebral haemorrhage-induced brain injury in rats. Clin Exp Pharmacol Physiol. 2007 Sep; 34(9):845-50.
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    Score: 0.013
  144. Kusaka I, Kusaka G, Zhou C, Ishikawa M, Nanda A, Granger DN, Zhang JH, Tang J. Role of AT1 receptors and NAD(P)H oxidase in diabetes-aggravated ischemic brain injury. Am J Physiol Heart Circ Physiol. 2004 Jun; 286(6):H2442-51.
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    Score: 0.010
  145. Sun Y, Zhang JQ, Zhang J, Lamparter S. Cardiac remodeling by fibrous tissue after infarction in rats. J Lab Clin Med. 2000 Apr; 135(4):316-23.
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    Score: 0.008
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