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Connection

Kim Kline to Animals

This is a "connection" page, showing publications Kim Kline has written about Animals.
Connection Strength

1.495
  1. Tanoto FR, Liew JH, Stocks CJ, Rawat D, Chong KKL, Pethe K, Antypas H, Kline KA. Gelatinase regulates the egress of intracellular replicating populations during Enterococcus faecalis infection. PLoS Pathog. 2026 Mar; 22(3):e1013738.
    View in: PubMed
    Score: 0.072
  2. da Silva RAG, Tien BYQ, Kao PHN, Antypas H, Celik C, Tan AZC, Ismail MH, Hu G, Chong KKL, Thibault G, Chen J, Kline KA. Enterococcus faecalis-derived lactic acid suppresses macrophage activation to facilitate persistent and polymicrobial wound infections. Cell Host Microbe. 2026 Feb 11; 34(2):245-262.e8.
    View in: PubMed
    Score: 0.071
  3. Tan AMZ, Celik C, Lee SYT, Veleba M, Manzano CS, Abdul RMK, Thibault G, Kline KA. Enterococcus faecalis redox metabolism activates the unfolded protein response to impair wound healing. Sci Adv. 2026 Jan 16; 12(3):eaeb5297.
    View in: PubMed
    Score: 0.071
  4. Antypas H, Schmidtchen V, Staiger WI, Yanhong LI, Tan RJW, Ng KKF, Neo CJY, Radhesh SM, Tanoto FR, da Silva RAG, Colomer-Winter C, Sch?tz SD, Kloehn J, Muthualagu Natarajan L, Manzano C, Wong JJ, Pethe K, Hasse B, Brugger SD, Wong SL, Van Tyne D, Zinkernagel AS, Kline KA. Loss of Fsr quorum sensing promotes biofilm formation and worsens outcomes in enterococcal infective endocarditis. Nat Commun. 2026 Jan 14; 17(1):1668.
    View in: PubMed
    Score: 0.071
  5. Stocks CJ, da Silva RAG, Antypas H, Jeyabalan N, Wong SL, Kline KA. Enterococcus faecalis persists and replicates intracellularly within neutrophils. Infect Immun. 2026 Jan 13; 94(1):e0036425.
    View in: PubMed
    Score: 0.071
  6. Ho FK, Lam LN, Matysik A, Watts TD, Wong JJ, Chong KKL, Choo PY, Tolar J, Low PM, Chua ZS, Paxman JJ, Heras B, Marsili E, Ajo-Franklin CM, Kline KA. Role of sortase-assembled Ebp pili in Enterococcus faecalis adhesion to iron oxides and its impact on extracellular electron transfer. Microbiol Spectr. 2025 Mar 04; 13(3):e0233724.
    View in: PubMed
    Score: 0.066
  7. Tan CAZ, Chong KKL, Yeong DYX, Ng CHM, Ismail MH, Yap ZH, Khetrapal V, Tay VSY, Drautz-Moses DI, Ali Y, Chen SL, Kline KA. Purine and carbohydrate availability drive Enterococcus faecalis fitness during wound and urinary tract infections. mBio. 2024 Jan 16; 15(1):e0238423.
    View in: PubMed
    Score: 0.061
  8. da Silva RAG, Wong JJ, Antypas H, Choo PY, Goh K, Jolly S, Liang C, Tay Kwan Sing L, Veleba M, Hu G, Chen J, Kline KA. Mitoxantrone targets both host and bacteria to overcome vancomycin resistance in Enterococcus faecalis. Sci Adv. 2023 02 22; 9(8):eadd9280.
    View in: PubMed
    Score: 0.058
  9. Wong JJ, Ho FK, Choo PY, Chong KKL, Ho CMB, Neelakandan R, Keogh D, Barkham T, Chen J, Liu CF, Kline KA. Escherichia coli BarA-UvrY regulates the pks island and kills Staphylococci via the genotoxin colibactin during interspecies competition. PLoS Pathog. 2022 09; 18(9):e1010766.
    View in: PubMed
    Score: 0.056
  10. da Silva RAG, Tay WH, Ho FK, Tanoto FR, Chong KKL, Choo PY, Ludwig A, Kline KA. Enterococcus faecalis alters endo-lysosomal trafficking to replicate and persist within mammalian cells. PLoS Pathog. 2022 04; 18(4):e1010434.
    View in: PubMed
    Score: 0.055
  11. Lam LN, Wong JJ, Chong KKL, Kline KA. Enterococcus faecalis Manganese Exporter MntE Alleviates Manganese Toxicity and Is Required for Mouse Gastrointestinal Colonization. Infect Immun. 2020 05 20; 88(6).
    View in: PubMed
    Score: 0.048
  12. Vajjala A, Biswas D, Tay WH, Hanski E, Kline KA. Streptolysin-induced endoplasmic reticulum stress promotes group A Streptococcal host-associated biofilm formation and necrotising fasciitis. Cell Microbiol. 2019 01; 21(1):e12956.
    View in: PubMed
    Score: 0.043
  13. Chong KKL, Tay WH, Janela B, Yong AMH, Liew TH, Madden L, Keogh D, Barkham TMS, Ginhoux F, Becker DL, Kline KA. Enterococcus faecalis Modulates Immune Activation and Slows Healing During Wound Infection. J Infect Dis. 2017 12 19; 216(12):1644-1654.
    View in: PubMed
    Score: 0.041
  14. Tien BYQ, Goh HMS, Chong KKL, Bhaduri-Tagore S, Holec S, Dress R, Ginhoux F, Ingersoll MA, Williams RBH, Kline KA. Enterococcus faecalis Promotes Innate Immune Suppression and Polymicrobial Catheter-Associated Urinary Tract Infection. Infect Immun. 2017 12; 85(12).
    View in: PubMed
    Score: 0.040
  15. Goh HMS, Yong MHA, Chong KKL, Kline KA. Model systems for the study of Enterococcal colonization and infection. Virulence. 2017 11 17; 8(8):1525-1562.
    View in: PubMed
    Score: 0.039
  16. Keogh D, Tay WH, Ho YY, Dale JL, Chen S, Umashankar S, Williams RBH, Chen SL, Dunny GM, Kline KA. Enterococcal Metabolite Cues Facilitate Interspecies Niche Modulation and Polymicrobial Infection. Cell Host Microbe. 2016 Oct 12; 20(4):493-503.
    View in: PubMed
    Score: 0.037
  17. Rousseau M, Goh HMS, Holec S, Albert ML, Williams RB, Ingersoll MA, Kline KA. Bladder catheterization increases susceptibility to infection that can be prevented by prophylactic antibiotic treatment. JCI Insight. 2016 09 22; 1(15):e88178.
    View in: PubMed
    Score: 0.037
  18. Tay WH, Chong KK, Kline KA. Polymicrobial-Host Interactions during Infection. J Mol Biol. 2016 08 28; 428(17):3355-71.
    View in: PubMed
    Score: 0.036
  19. Kline KA, Lewis AL. Gram-Positive Uropathogens, Polymicrobial Urinary Tract Infection, and the Emerging Microbiota of the Urinary Tract. Microbiol Spectr. 2016 04; 4(2).
    View in: PubMed
    Score: 0.036
  20. Kline KA, Schwartz DJ, Gilbert NM, Lewis AL. Impact of host age and parity on susceptibility to severe urinary tract infection in a murine model. PLoS One. 2014; 9(5):e97798.
    View in: PubMed
    Score: 0.032
  21. Kline KA, Schwartz DJ, Gilbert NM, Hultgren SJ, Lewis AL. Immune modulation by group B Streptococcus influences host susceptibility to urinary tract infection by uropathogenic Escherichia coli. Infect Immun. 2012 Dec; 80(12):4186-94.
    View in: PubMed
    Score: 0.028
  22. Kline KA, Schwartz DJ, Lewis WG, Hultgren SJ, Lewis AL. Immune activation and suppression by group B streptococcus in a murine model of urinary tract infection. Infect Immun. 2011 Sep; 79(9):3588-95.
    View in: PubMed
    Score: 0.026
  23. Kline KA, Ingersoll MA, Nielsen HV, Sakinc T, Henriques-Normark B, Gatermann S, Caparon MG, Hultgren SJ. Characterization of a novel murine model of Staphylococcus saprophyticus urinary tract infection reveals roles for Ssp and SdrI in virulence. Infect Immun. 2010 May; 78(5):1943-51.
    View in: PubMed
    Score: 0.024
  24. Park SK, Sanders BG, Kline K. Tocotrienols induce apoptosis in breast cancer cell lines via an endoplasmic reticulum stress-dependent increase in extrinsic death receptor signaling. Breast Cancer Res Treat. 2010 Nov; 124(2):361-75.
    View in: PubMed
    Score: 0.024
  25. Jia L, Yu W, Wang P, Sanders BG, Kline K. In vivo and in vitro studies of anticancer actions of alpha-TEA for human prostate cancer cells. Prostate. 2008 Jun 01; 68(8):849-60.
    View in: PubMed
    Score: 0.021
  26. Yu W, Jia L, Wang P, Lawson KA, Simmons-Menchaca M, Park SK, Sun L, Sanders BG, Kline K. In vitro and in vivo evaluation of anticancer actions of natural and synthetic vitamin E forms. Mol Nutr Food Res. 2008 Apr; 52(4):447-56.
    View in: PubMed
    Score: 0.021
  27. Riedel SB, Fischer SM, Sanders BG, Kline K. Vitamin E analog, alpha-tocopherol ether-linked acetic acid analog, alone and in combination with celecoxib, reduces multiplicity of ultraviolet-induced skin cancers in mice. Anticancer Drugs. 2008 Feb; 19(2):175-81.
    View in: PubMed
    Score: 0.020
  28. Wang P, Jia L, Sanders BG, Kline K. Liposomal or nanoparticle alpha-TEA reduced 66cl-4 murine mammary cancer burden and metastasis. Drug Deliv. 2007 Nov; 14(8):497-505.
    View in: PubMed
    Score: 0.020
  29. Kapitan M, Niemiec MJ, Millet N, Brandt P, Chowdhury MEK, Czapka A, Abdissa K, Hoffmann F, Lange A, Veleba M, Nietzsche S, Mosig AS, L?ffler B, Marquet M, Makarewicz O, Kline KA, Vylkova S, Swidergall M, Jacobsen ID. Synergistic interactions between Candida albicans and Enterococcus faecalis promote toxin-dependent host cell damage. Proc Natl Acad Sci U S A. 2025 Nov 18; 122(46):e2505310122.
    View in: PubMed
    Score: 0.018
  30. Li W, Tan CH, Baek JS, Jiang L, Ng NKJ, Chong KKL, Wong JJ, Gao L, Kline KA, Loo SCJ. Anti-Intracellular MRSA Activity of Antibiotic-Loaded Lipid-Polymer Hybrid Nanoparticles and Their Effectiveness in Murine Skin Wound Infection Models. ACS Infect Dis. 2025 Mar 14; 11(3):750-761.
    View in: PubMed
    Score: 0.017
  31. Kline K, Yu W, Sanders BG. Vitamin E and breast cancer. J Nutr. 2004 12; 134(12 Suppl):3458S-3462S.
    View in: PubMed
    Score: 0.016
  32. Archambaud C, Nunez N, da Silva RAG, Kline KA, Serror P. Enterococcus faecalis: an overlooked cell invader. Microbiol Mol Biol Rev. 2024 Sep 26; 88(3):e0006924.
    View in: PubMed
    Score: 0.016
  33. Zhang S, Lawson KA, Simmons-Menchaca M, Sun L, Sanders BG, Kline K. Vitamin E analog alpha-TEA and celecoxib alone and together reduce human MDA-MB-435-FL-GFP breast cancer burden and metastasis in nude mice. Breast Cancer Res Treat. 2004 Sep; 87(2):111-21.
    View in: PubMed
    Score: 0.016
  34. Celik C, Lee STT, Tanoto FR, Veleba M, Kline K, Thibault G. Decoding the complexity of delayed wound healing following Enterococcus faecalis infection. Elife. 2024 May 20; 13.
    View in: PubMed
    Score: 0.016
  35. da Silva RAG, Stocks CJ, Hu G, Kline KA, Chen J. Bosutinib Stimulates Macrophage Survival, Phagocytosis, and Intracellular Killing of Bacteria. ACS Infect Dis. 2024 05 10; 10(5):1725-1738.
    View in: PubMed
    Score: 0.016
  36. Lee WL, Sinha A, Lam LN, Loo HL, Liang J, Ho P, Cui L, Chan CSC, Begley T, Kline KA, Dedon P. An RNA modification enzyme directly senses reactive oxygen species for translational regulation in Enterococcus faecalis. Nat Commun. 2023 07 11; 14(1):4093.
    View in: PubMed
    Score: 0.015
  37. Lawson KA, Anderson K, Menchaca M, Atkinson J, Sun L, Knight V, Gilbert BE, Conti C, Sanders BG, Kline K. Novel vitamin E analogue decreases syngeneic mouse mammary tumor burden and reduces lung metastasis. Mol Cancer Ther. 2003 May; 2(5):437-44.
    View in: PubMed
    Score: 0.015
  38. Ferrer MS, Canisso IF, Ellerbrock RE, Podico G, Lister BN, Hurley DJ, Kline K, Palomares RA. Optimization of cryopreservation protocols for cooled-transported stallion semen. Anim Reprod Sci. 2020 Oct; 221:106581.
    View in: PubMed
    Score: 0.012
  39. Antonoplis A, Zang X, Huttner MA, Chong KKL, Lee YB, Co JY, Amieva MR, Kline KA, Wender PA, Cegelski L. A Dual-Function Antibiotic-Transporter Conjugate Exhibits Superior Activity in Sterilizing MRSA Biofilms and Killing Persister Cells. J Am Chem Soc. 2018 11 28; 140(47):16140-16151.
    View in: PubMed
    Score: 0.011
  40. Lim K, Saravanan R, Chong KKL, Goh SHM, Chua RRY, Tambyah PA, Chang MW, Kline KA, Leong SSJ. Anhydrous polymer-based coating with sustainable controlled release functionality for facile, efficacious impregnation, and delivery of antimicrobial peptides. Biotechnol Bioeng. 2018 08; 115(8):2000-2012.
    View in: PubMed
    Score: 0.010
  41. Zhou C, Wu Y, Thappeta KRV, Subramanian JTL, Pranantyo D, Kang ET, Duan H, Kline K, Chan-Park MB. In Vivo Anti-Biofilm and Anti-Bacterial Non-Leachable Coating Thermally Polymerized on Cylindrical Catheter. ACS Appl Mater Interfaces. 2017 Oct 18; 9(41):36269-36280.
    View in: PubMed
    Score: 0.010
  42. Yu W, Sanders BG, Kline K. RRR-alpha-tocopheryl succinate inhibits EL4 thymic lymphoma cell growth by inducing apoptosis and DNA synthesis arrest. Nutr Cancer. 1997; 27(1):92-101.
    View in: PubMed
    Score: 0.009
  43. Roach J, Schnobrich M, Ellerbrock R, Feijo L, Bradecamp E, Alvarenga MA, Kline K, Canisso I. Comparison of cushioned centrifugation and SpermFilter filtration on longevity and morphology of cooled-stored equine semen. Vet Rec. 2016 Mar 05; 178(10):241.
    View in: PubMed
    Score: 0.009
  44. Yu W, Sanders BG, Kline K. Modulation of murine EL-4 thymic lymphoma cell proliferation and cytokine production by vitamin E succinate. Nutr Cancer. 1996; 25(2):137-49.
    View in: PubMed
    Score: 0.009
  45. Simmons-Menchaca M, Qian M, Yu W, Sanders BG, Kline K. RRR-alpha-tocopheryl succinate inhibits DNA synthesis and enhances the production and secretion of biologically active transforming growth factor-beta by avian retrovirus-transformed lymphoid cells. Nutr Cancer. 1995; 24(2):171-85.
    View in: PubMed
    Score: 0.008
  46. Korte-Berwanger M, Sakinc T, Kline K, Nielsen HV, Hultgren S, Gatermann SG. Significance of the D-serine-deaminase and D-serine metabolism of Staphylococcus saprophyticus for virulence. Infect Immun. 2013 Dec; 81(12):4525-33.
    View in: PubMed
    Score: 0.008
  47. Nielsen HV, Guiton PS, Kline KA, Port GC, Pinkner JS, Neiers F, Normark S, Henriques-Normark B, Caparon MG, Hultgren SJ. The metal ion-dependent adhesion site motif of the Enterococcus faecalis EbpA pilin mediates pilus function in catheter-associated urinary tract infection. mBio. 2012; 3(4):e00177-12.
    View in: PubMed
    Score: 0.007
  48. Guiton PS, Cusumano CK, Kline KA, Dodson KW, Han Z, Janetka JW, Henderson JP, Caparon MG, Hultgren SJ. Combinatorial small-molecule therapy prevents uropathogenic Escherichia coli catheter-associated urinary tract infections in mice. Antimicrob Agents Chemother. 2012 Sep; 56(9):4738-45.
    View in: PubMed
    Score: 0.007
  49. Ingersoll MA, Kline KA, Nielsen HV, Hultgren SJ. G-CSF induction early in uropathogenic Escherichia coli infection of the urinary tract modulates host immunity. Cell Microbiol. 2008 Dec; 10(12):2568-78.
    View in: PubMed
    Score: 0.005
  50. Rosen DA, Hung CS, Kline KA, Hultgren SJ. Streptozocin-induced diabetic mouse model of urinary tract infection. Infect Immun. 2008 Sep; 76(9):4290-8.
    View in: PubMed
    Score: 0.005
  51. Kline K, Sanders BG. Suppression of Con A mitogen-induced proliferation of normal spleen cells by macrophages from chickens with hereditary muscular dystrophy. J Immunol. 1984 Jun; 132(6):2813-9.
    View in: PubMed
    Score: 0.004
  52. Kline K, Sanders BG. Developmental profile of chicken splenic lymphocyte responsiveness to Con A and PHA and studies on chicken splenic and bone marrow cells capable of inhibiting mitogen-stimulated blastogenic responses of adult splenic lymphocytes. J Immunol. 1980 Oct; 125(4):1792-7.
    View in: PubMed
    Score: 0.003
  53. Kadekoppala M, Kline K, Akompong T, Haldar K. Stable expression of a new chimeric fluorescent reporter in the human malaria parasite Plasmodium falciparum. Infect Immun. 2000 Apr; 68(4):2328-32.
    View in: PubMed
    Score: 0.003
  54. Speck P, Kline KA, Cheresh P, Longnecker R. Epstein-Barr virus lacking latent membrane protein 2 immortalizes B cells with efficiency indistinguishable from that of wild-type virus. J Gen Virol. 1999 Aug; 80 ( Pt 8):2193-2203.
    View in: PubMed
    Score: 0.003
  55. Bauer PI, Kline K, Kun E. Apparent role of adenosine diphosphoribosyl transferase in the development of Mytilus edulis and the inhibition of differentiation by ligands of the enzyme protein. Proc Soc Exp Biol Med. 1991 Apr; 196(4):396-400.
    View in: PubMed
    Score: 0.002
  56. Rao A, Kline K, Sanders BG. Immune abnormalities in avian erythroblastosis virus-infected chickens. Cancer Res. 1990 Aug 01; 50(15):4764-70.
    View in: PubMed
    Score: 0.002
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
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