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James Chambers

TitleProfessor
InstitutionUniversity of Texas at San Antonio
DepartmentBiology
Address1 UTSA Cir
San Antonio TX 78249
Phone(210) 458-5663
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    Collapse Overview 
    Collapse overview
    Dr. Chambers’ research interests focus on biosensors, influenza epidemiology, and Francisella tularensis. He seeks to understand the processes that make it possible to development new and novel treatment regimes, with special regard to treatments for illness associated with F. tularensis. Dr. Chambers’ current research focus is the interaction of host tissue nonspecific Alkaline Phosphatase and F. tularensis dnaK. Like many microbes, F. tularensis has evolved specific physico-chemical interactions with host proteins which affect the host’s ability to neutralize the pathogen. Understanding these processes makes possible the development of many new and novel treatment regimes.

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Takaichi Y, Chambers JK, Inoue H, Ano Y, Takashima A, Nakayama H, Uchida K. Phosphorylation and oligomerization of a-synuclein associated with GSK-3ß activation in the rTg4510 mouse model of tauopathy. Acta Neuropathol Commun. 2020 06 19; 8(1):86. PMID: 32560668.
      Citations:    Fields:    
    2. Keck J, Chambers JP, Kancharla A, Bashir DH, Henley L, Schenkel K, Castillo K, Neal Guentzel M, Gupta R, Arulanandam BP. The Role of MicroRNA-155 in Chlamydia muridarum Infected lungs. Microbes Infect. 2020 Feb 19. PMID: 32084556.
      Citations:    Fields:    
    3. Desamero MJ, Kakuta S, Tang Y, Chambers JK, Uchida K, Estacio MA, Cervancia C, Kominami Y, Ushio H, Nakayama J, Nakayama H, Kyuwa S. Tumor-suppressing potential of stingless bee propolis in in vitro and in vivo models of differentiated-type gastric adenocarcinoma. Sci Rep. 2019 12 23; 9(1):19635. PMID: 31873082.
      Citations:    Fields:    
    4. May HC, Yu JJ, Shrihari S, Seshu J, Klose KE, Cap AP, Chambers JP, Guentzel MN, Arulanandam BP. Thioredoxin Modulates Cell Surface Hydrophobicity in Acinetobacter baumannii. Front Microbiol. 2019; 10:2849. PMID: 31921031.
      Citations:    
    5. Morimoto A, Uchida K, Chambers JK, Sato K, Hong J, Sanjoba C, Matsumoto Y, Yamagishi J, Goto Y. Hemophagocytosis induced by Leishmania donovani infection is beneficial to parasite survival within macrophages. PLoS Negl Trop Dis. 2019 11; 13(11):e0007816. PMID: 31738750.
      Citations:    Fields:    Translation:AnimalsCells
    6. Yu M, Chambers JK, Tsuzuki M, Yamashita N, Ushigusa T, Haga T, Nakayama H, Uchida K. Pigmented viral plaque and basal cell tumor associated with canine papillomavirus infection in Pug dogs. J Vet Med Sci. 2019 Nov 29; 81(11):1643-1648. PMID: 31554746.
      Citations:    Fields:    Translation:AnimalsCells
    7. Keck J, Chambers JP, Forsthuber T, Gupta R, Arulanandam BP. A modified method for rapid quantification of Chlamydia muridarum using Fluorospot. MethodsX. 2019; 6:1925-1932. PMID: 31538048.
      Citations:    
    8. Wong WF, Chambers JP, Gupta R, Arulanandam BP. Chlamydia and Its Many Ways of Escaping the Host Immune System. J Pathog. 2019; 2019:8604958. PMID: 31467721.
      Citations:    
    9. May HC, Yu JJ, Zhang H, Wang Y, Cap AP, Chambers JP, Guentzel MN, Arulanandam BP. Thioredoxin-A is a virulence factor and mediator of the type IV pilus system in Acinetobacter baumannii. PLoS One. 2019; 14(7):e0218505. PMID: 31265467.
      Citations: 1     Fields:    Translation:AnimalsCells
    10. Yamashita-Kawanishi N, Tsuzuki M, Wei Z, Kok MK, Ishiyama D, Chambers JK, Uchida K, Dong J, Shimakura H, Haga T. Identification of bovine papillomavirus type 1 and 2 from bovine anogenital fibropapillomas. J Vet Med Sci. 2019 Jul 19; 81(7):1000-1005. PMID: 31155549.
      Citations:    Fields:    Translation:AnimalsCells
    11. Yoshimoto S, Kato D, Kamoto S, Yamamoto K, Tsuboi M, Shinada M, Ikeda N, Tanaka Y, Yoshitake R, Eto S, Saeki K, Chambers JK, Kinoshita R, Uchida K, Nishimura R, Nakagawa T. Detection of human epidermal growth factor receptor 2 overexpression in canine anal sac gland carcinoma. J Vet Med Sci. 2019 Jul 19; 81(7):1034-1039. PMID: 31142682.
      Citations: 1     Fields:    Translation:Animals
    12. Son NV, Uchida K, Thongtharb A, Chambers JK, Kishimoto TE, Tomiyasu H, Ohmi A, Tsujimoto H, Nakayama H. Establishment of cell line and in vivo mouse model of canine Langerhans cell histiocytosis. Vet Comp Oncol. 2019 Sep; 17(3):345-353. PMID: 30884050.
      Citations:    Fields:    Translation:AnimalsCells
    13. Kok MK, Yamashita-Kawanishi N, Chambers JK, Haritani M, Ushigusa T, Haga T, Nakayama H, Uchida K. Pathologic characterization of Felis catus papillomavirus type 5 (FcaPV-5)-associated viral plaques and Bowenoid in situ carcinoma in a Domestic Shorthair cat. J Vet Med Sci. 2019 May 11; 81(5):660-666. PMID: 30905908.
      Citations:    Fields:    Translation:AnimalsCells
    14. Tsuboi M, Sakai K, Maeda S, Chambers JK, Yonezawa T, Matsuki N, Uchida K, Nakayama H. Assessment of HER2 Expression in Canine Urothelial Carcinoma of the Urinary Bladder. Vet Pathol. 2019 05; 56(3):369-376. PMID: 30612533.
      Citations: 1     Fields:    Translation:Animals
    15. Takaichi Y, Ano Y, Chambers JK, Uchida K, Takashima A, Nakayama H. Deposition of Phosphorylated a-Synuclein in the rTg4510 Mouse Model of Tauopathy. J Neuropathol Exp Neurol. 2018 10 01; 77(10):920-928. PMID: 30107539.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    16. Shimakura H, Dong J, Zhu W, Chambers JK, Uchida K, Kiriki K, Uematsu M, Goto Y, Yasuda M, Yamashita-Kawanishi N, Tsuzuki M, LE DT, Hatama S, Haga T. Full genome analysis of bovine papillomavirus type 1 derived from a calf with severe cutaneous multiple papillomatosis. J Vet Med Sci. 2018 Nov 09; 80(11):1691-1695. PMID: 30210094.
      Citations:    Fields:    Translation:AnimalsCells
    17. Kok MK, Chambers JK, Ong SM, Nakayama H, Uchida K. Hierarchical Cluster Analysis of Cytokeratins and Stem Cell Expression Profiles of Canine Cutaneous Epithelial Tumors. Vet Pathol. 2018 11; 55(6):821-837. PMID: 30071783.
      Citations: 1     Fields:    Translation:AnimalsCells
    18. Ketter PM, Yu JJ, Guentzel MN, May HC, Gupta R, Eppinger M, Klose KE, Seshu J, Chambers JP, Cap AP, Arulanandam BP. Acinetobacter baumannii Gastrointestinal Colonization Is Facilitated by Secretory IgA Which Is Reductively Dissociated by Bacterial Thioredoxin A. mBio. 2018 07 10; 9(4). PMID: 29991584.
      Citations:    Fields:    Translation:AnimalsCells
    19. Yamashita-Kawanishi N, Sawanobori R, Matsumiya K, Uema A, Chambers JK, Uchida K, Shimakura H, Tsuzuki M, Chang CY, Chang HW, Haga T. Detection of felis catus papillomavirus type 3 and 4 DNA from squamous cell carcinoma cases of cats in Japan. J Vet Med Sci. 2018 Aug 10; 80(8):1236-1240. PMID: 29877210.
      Citations: 1     Fields:    Translation:AnimalsCells
    20. Matsumoto I, Chambers JK, Nibe K, Kinoshita R, Nishimura R, Nakayama H, Uchida K. Histopathologic and Immunohistochemistry Findings in Feline Renal Cell Carcinoma. Vet Pathol. 2018 09; 55(5):663-672. PMID: 29759053.
      Citations:    Fields:    Translation:Animals
    21. Desamero MJ, Kakuta S, Chambers JK, Uchida K, Hachimura S, Takamoto M, Nakayama J, Nakayama H, Kyuwa S. Orally administered brown seaweed-derived ß-glucan effectively restrained development of gastric dysplasia in A4gnt KO mice that spontaneously develop gastric adenocarcinoma. Int Immunopharmacol. 2018 Jul; 60:211-220. PMID: 29763881.
      Citations: 2     Fields:    Translation:Animals
    22. Maeda S, Tomiyasu H, Tsuboi M, Inoue A, Ishihara G, Uchikai T, Chambers JK, Uchida K, Yonezawa T, Matsuki N. Comprehensive gene expression analysis of canine invasive urothelial bladder carcinoma by RNA-Seq. BMC Cancer. 2018 04 27; 18(1):472. PMID: 29699519.
      Citations: 3     Fields:    Translation:AnimalsCells
    23. Sugimoto S, Maeda S, Tsuboi M, Saeki K, Chambers JK, Yonezawa T, Fukushima K, Fujiwara R, Uchida K, Tsujimoto H, Matsuki N, Ohno K. Multiple acquired portosystemic shunts secondary to primary hypoplasia of the portal vein in a cat. J Vet Med Sci. 2018 Jun 06; 80(6):874-877. PMID: 29628453.
      Citations:    Fields:    Translation:Animals
    24. May HC, Yu JJ, Guentzel MN, Chambers JP, Cap AP, Arulanandam BP. Repurposing Auranofin, Ebselen, and PX-12 as Antimicrobial Agents Targeting the Thioredoxin System. Front Microbiol. 2018; 9:336. PMID: 29556223.
      Citations:    
    25. Trivedi NH, Yu JJ, Hung CY, Doelger RP, Navara CS, Armitige LY, Seshu J, Sinai AP, Chambers JP, Guentzel MN, Arulanandam BP. Microbial co-infection alters macrophage polarization, phagosomal escape, and microbial killing. Innate Immun. 2018 04; 24(3):152-162. PMID: 29482417.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    26. Chambers JK, Shiga T, Takimoto H, Dohata A, Miwa Y, Nakayama H, Uchida K. Proliferative Lesions of the Endometrium of 50 Four-Toed Hedgehogs ( Atelerix albiventris). Vet Pathol. 2018 07; 55(4):562-571. PMID: 29448904.
      Citations: 1     Fields:    Translation:Animals
    27. Mineshige T, Ogihara K, Kamiie J, Sugahara G, Chambers JK, Uchida K, Madarame H, Shirota K. Increased expression of the stromal fibroblast-secreted periostin in canine squamous cell carcinomas. J Vet Med Sci. 2018 Mar 24; 80(3):473-479. PMID: 29415922.
      Citations: 1     Fields:    Translation:AnimalsCells
    28. Ushigusa T, Koyama Y, Ito T, Watanabe K, Chambers JK, Hasegawa A, Uchida K, Kanegi R, Hatoya S, Inaba T, Sugiura K. Innate immunity mediated by dendritic cells/macrophages plays a central role in the early period in tumor treatment using gene of Mycobacterium tuberculosis antigen. J Vet Med Sci. 2018 Feb 09; 80(2):190-196. PMID: 29311492.
      Citations:    Fields:    Translation:AnimalsCells
    29. Chambers J, Pope E, Bungay K, Cohen J, Ciarametaro M, Dubois R, Neumann PJ. A Comparison of Coverage Restrictions for Biopharmaceuticals and Medical Procedures. Value Health. 2018 04; 21(4):400-406. PMID: 29680096.
      Citations:    Fields:    Translation:Humans
    30. Shiga T, Uchida K, Chambers JK, Nakayama H. Immunohistochemical analysis of canine and feline muscle disorders using formalin-fixed, paraffin-embedded tissues. J Vet Diagn Invest. 2017 Nov; 29(6):805-813. PMID: 28599613.
      Citations: 2     Fields:    Translation:Animals
    31. Ainsworth S, Ketter PM, Yu JJ, Grimm RC, May HC, Cap AP, Chambers JP, Guentzel MN, Arulanandam BP. Vaccination with a live attenuated Acinetobacter baumannii deficient in thioredoxin provides protection against systemic Acinetobacter infection. Vaccine. 2017 06 08; 35(26):3387-3394. PMID: 28522011.
      Citations: 3     Fields:    Translation:AnimalsCells
    32. Lin YH, Romo JA, Smith TC, Reyes AN, Karna SLR, Miller CL, Van Laar TA, Yendapally R, Chambers JP, Seshu J. Spermine and Spermidine Alter Gene Expression and Antigenic Profile of Borrelia burgdorferi. Infect Immun. 2017 03; 85(3). PMID: 28052993.
      Citations: 2     Fields:    Translation:HumansCells
    33. Matsumoto I, Uchida K, Nakashima K, Hiyoshi S, Chambers JK, Tsujimoto H, Nakayama H. IgA Antibodies Against Gliadin and Tissue Transglutaminase in Dogs With Chronic Enteritis and Intestinal T-Cell Lymphoma. Vet Pathol. 2018 01; 55(1):98-107. PMID: 29254476.
      Citations: 1     Fields:    Translation:Animals
    34. Tsuboi M, Watanabe M, Nibe K, Yoshimi N, Kato A, Sakaguchi M, Yamato O, Tanaka M, Kuwamura M, Kushida K, Ishikura T, Harada T, Chambers JK, Sugano S, Uchida K, Nakayama H. Identification of the PLA2G6 c.1579G>A Missense Mutation in Papillon Dog Neuroaxonal Dystrophy Using Whole Exome Sequencing Analysis. PLoS One. 2017; 12(1):e0169002. PMID: 28107443.
      Citations: 5     Fields:    Translation:AnimalsCells
    35. Wali S, Gupta R, Yu JJ, Lanka GKK, Chambers JP, Guentzel MN, Zhong G, Murthy AK, Arulanandam BP. Chlamydial protease-like activity factor mediated protection against C. trachomatis in guinea pigs. Immunol Cell Biol. 2017 05; 95(5):454-460. PMID: 27990018.
      Citations: 1     Fields:    Translation:AnimalsCellsPHPublic Health
    36. Gupta R, Arkatkar T, Keck J, Koundinya GK, Castillo K, Hobel S, Chambers JP, Yu JJ, Guentzel MN, Aigner A, Christenson LK, Arulanandam BP. Antigen specific immune response in Chlamydia muridarum genital infection is dependent on murine microRNAs-155 and -182. Oncotarget. 2016 10 04; 7(40):64726-64742. PMID: 27556515.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    37. Watanabe K, Uchida K, Chambers JK, Ushio N, Nakayama H. Deposition, Clearance, and Reinduction of Amyloid A Amyloid in Interleukin 1 Receptor Antagonist Knockout Mice. Vet Pathol. 2017 01; 54(1):99-110. PMID: 27565681.
      Citations:    Fields:    Translation:Animals
    38. Ma YH, Islam GS, Wu Y, Sabour PM, Chambers JR, Wang Q, Wu SX, Griffiths MW. Temporal distribution of encapsulated bacteriophages during passage through the chick gastrointestinal tract. Poult Sci. 2016 Dec 01; 95(12):2911-2920. PMID: 27587723.
      Citations:    Fields:    Translation:AnimalsCells
    39. Rodriguez AR, Yu JJ, Navara C, Chambers JP, Guentzel MN, Arulanandam BP. Contribution of Fc?RI-associated vesicles to mast cell-macrophage communication following Francisella tularensis infection. Innate Immun. 2016 10; 22(7):567-74. PMID: 27554051.
      Citations: 3     Fields:    Translation:AnimalsCells
    40. Murakami S, Endoh M, Kobayashi T, Takenaka-Uema A, Chambers JK, Uchida K, Nishihara M, Hause B, Horimoto T. Influenza D Virus Infection in Herd of Cattle, Japan. Emerg Infect Dis. 2016 08; 22(8):1517-9. PMID: 27434213.
      Citations: 23     Fields:    Translation:AnimalsCells
    41. Wali S, Gupta R, Yu JJ, Mfuh A, Gao X, Guentzel MN, Chambers JP, Abu Bakar S, Zhong G, Arulanandam BP. Guinea pig genital tract lipidome reveals in vivo and in vitro regulation of phosphatidylcholine 16:0/18:1 and contribution to Chlamydia trachomatis serovar D infectivity. Metabolomics. 2016 Apr; 12(4). PMID: 27642272.
      Citations:    Fields:    
    42. Morimoto A, Omachi S, Osada Y, Chambers JK, Uchida K, Sanjoba C, Matsumoto Y, Goto Y. Hemophagocytosis in Experimental Visceral Leishmaniasis by Leishmania donovani. PLoS Negl Trop Dis. 2016 Mar; 10(3):e0004505. PMID: 26942577.
      Citations: 2     Fields:    Translation:AnimalsCells
    43. Thongtharb A, Uchida K, Chambers JK, Miwa Y, Murata Y, Nakayama H. Histological and immunohistochemical features of histiocytic sarcoma in four domestic ferrets (Mustela putorius furo). J Vet Diagn Invest. 2016 Mar; 28(2):165-70. PMID: 26965237.
      Citations: 1     Fields:    Translation:Animals
    44. Youssef SA, Capucchio MT, Rofina JE, Chambers JK, Uchida K, Nakayama H, Head E. Pathology of the Aging Brain in Domestic and Laboratory Animals, and Animal Models of Human Neurodegenerative Diseases. Vet Pathol. 2016 Mar; 53(2):327-48. PMID: 26869150.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    45. Lanka GK, Yu JJ, Gong S, Gupta R, Mustafa SB, Murthy AK, Zhong G, Chambers JP, Guentzel MN, Arulanandam BP. IgA modulates respiratory dysfunction as a sequela to pulmonary chlamydial infection as neonates. Pathog Dis. 2016 Apr; 74(3). PMID: 26755533.
      Citations:    Fields:    Translation:AnimalsCells
    46. Chambers JK, Tokuda T, Uchida K, Ishii R, Tatebe H, Takahashi E, Tomiyama T, Une Y, Nakayama H. The domestic cat as a natural animal model of Alzheimer's disease. Acta Neuropathol Commun. 2015 Dec 10; 3:78. PMID: 26651821.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    47. Arkatkar T, Gupta R, Li W, Yu JJ, Wali S, Neal Guentzel M, Chambers JP, Christenson LK, Arulanandam BP. Murine MicroRNA-214 regulates intracellular adhesion molecule (ICAM1) gene expression in genital Chlamydia muridarum infection. Immunology. 2015 Aug; 145(4):534-42. PMID: 25865776.
      Citations: 4     Fields:    Translation:AnimalsCells
    48. Rodriguez AR, Plascencia-Villa G, Witt CM, Yu JJ, José-Yacamán M, Chambers JP, Perry G, Guentzel MN, Arulanandam BP. Chlamydia pneumoniae promotes dysfunction of pancreatic beta cells. Cell Immunol. 2015 Jun; 295(2):83-91. PMID: 25863744.
      Citations: 2     Fields:    Translation:AnimalsCells
    49. Kanemoto H, Morikawa R, Chambers JK, Kasahara K, Hanafusa Y, Uchida K, Ohno K, Nakayama H. Common variable immune deficiency in a Pomeranian with Pneumocystis carinii pneumonia. J Vet Med Sci. 2015 Jun; 77(6):715-9. PMID: 25715954.
      Citations: 1     Fields:    Translation:AnimalsCells
    50. Wali S, Gupta R, Veselenak RL, Li Y, Yu JJ, Murthy AK, Cap AP, Guentzel MN, Chambers JP, Zhong G, Rank RG, Pyles RB, Arulanandam BP. Use of a Guinea pig-specific transcriptome array for evaluation of protective immunity against genital chlamydial infection following intranasal vaccination in Guinea pigs. PLoS One. 2014; 9(12):e114261. PMID: 25502875.
      Citations: 6     Fields:    Translation:AnimalsCellsPHPublic Health
    51. Watanabe K, Uchida K, Chambers JK, Tei M, Shoji A, Ushio N, Nakayama H. Experimental transmission of AA amyloidosis by injecting the AA amyloid protein into interleukin-1 receptor antagonist knockout (IL-1raKO) mice. Vet Pathol. 2015 May; 52(3):505-12. PMID: 25391376.
      Citations: 3     Fields:    Translation:Animals
    52. Hirose N, Uchida K, Matsunaga S, Chambers JK, Nakayama H. Expression of cell adhesion molecules in canine choroid plexus tumors. J Vet Med Sci. 2015 Feb; 77(2):255-9. PMID: 25373880.
      Citations:    Fields:    Translation:Animals
    53. Gupta R, Wali S, Yu JJ, Chambers JP, Zhong G, Murthy AK, Bakar SA, Guentzel MN, Arulanandam BP. In vivo whole animal body imaging reveals colonization of Chlamydia muridarum to the lower genital tract at early stages of infection. Mol Imaging Biol. 2014 Oct; 16(5):635-41. PMID: 24723309.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    54. Imura K, Chambers JK, Uchida K, Nomura S, Suzuki S, Nakayama H, Miwa Y. Herpes simplex virus type 1 infection in two pet marmosets in Japan. J Vet Med Sci. 2014 Dec; 76(12):1667-70. PMID: 25649955.
      Citations:    Fields:    Translation:AnimalsCells
    55. Tanaka Y, Chambers JK, Matsuwaki T, Yamanouchi K, Nishihara M. Possible involvement of lysosomal dysfunction in pathological changes of the brain in aged progranulin-deficient mice. Acta Neuropathol Commun. 2014 Jul 15; 2:78. PMID: 25022663.
      Citations: 33     Fields:    Translation:HumansAnimalsCells
    56. Ketter PM, Guentzel MN, Schaffer B, Herzig M, Wu X, Montgomery RK, Parida BK, Fedyk CG, Yu JJ, Jorgensen J, Chambers JP, Cap AP, Arulanandam BP. Severe Acinetobacter baumannii sepsis is associated with elevation of pentraxin 3. Infect Immun. 2014 Sep; 82(9):3910-8. PMID: 25001601.
      Citations: 4     Fields:    Translation:AnimalsCells
    57. Gupta R, Arkatkar T, Yu JJ, Wali S, Haskins WE, Chambers JP, Murthy AK, Bakar SA, Guentzel MN, Arulanandam BP. Chlamydia muridarum infection associated host MicroRNAs in the murine genital tract and contribution to generation of host immune response. Am J Reprod Immunol. 2015 Feb; 73(2):126-40. PMID: 24976530.
      Citations: 7     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    58. Ketter P, Guentzel MN, Chambers JP, Jorgensen J, Murray CK, Cap AP, Yu JJ, Eppinger M, Arulanandam BP. Genome Sequences of Four Acinetobacter baumannii-A. calcoaceticus Complex Isolates from Combat-Related Infections Sustained in the Middle East. Genome Announc. 2014 Feb 06; 2(1). PMID: 24503987.
      Citations:    
    59. Li W, Murthy AK, Lanka GK, Chetty SL, Yu JJ, Chambers JP, Zhong G, Forsthuber TG, Guentzel MN, Arulanandam BP. A T cell epitope-based vaccine protects against chlamydial infection in HLA-DR4 transgenic mice. Vaccine. 2013 Nov 19; 31(48):5722-8. PMID: 24096029.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    60. Kamalakaran S, Chaganty BK, Gupta R, Guentzel MN, Chambers JP, Murthy AK, Arulanandam BP. Vaginal chlamydial clearance following primary or secondary infection in mice occurs independently of TNF-a. Front Cell Infect Microbiol. 2013; 3:11. PMID: 23483844.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    61. Signarovitz AL, Ray HJ, Yu JJ, Guentzel MN, Chambers JP, Klose KE, Arulanandam BP. Mucosal immunization with live attenuated Francisella novicida U112?iglB protects against pulmonary F. tularensis SCHU S4 in the Fischer 344 rat model. PLoS One. 2012; 7(10):e47639. PMID: 23118885.
      Citations: 13     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    62. Chambers JK, Uchida K, Harada T, Tsuboi M, Sato M, Kubo M, Kawaguchi H, Miyoshi N, Tsujimoto H, Nakayama H. Neurofibrillary tangles and the deposition of a beta amyloid peptide with a novel N-terminal epitope in the brains of wild Tsushima leopard cats. PLoS One. 2012; 7(10):e46452. PMID: 23056312.
      Citations: 6     Fields:    Translation:AnimalsCells
    63. Hunter C, Rodriguez A, Yu JJ, Chambers J, Guentzel MN, Arulanandam B. Comparison of bone marrow-derived and mucosal mast cells in controlling intramacrophage Francisella tularensis replication. Exp Biol Med (Maywood). 2012 Jun; 237(6):617-21. PMID: 22688822.
      Citations:    Fields:    Translation:AnimalsCells
    64. Van Laar TA, Lin YH, Miller CL, Karna SL, Chambers JP, Seshu J. Effect of levels of acetate on the mevalonate pathway of Borrelia burgdorferi. PLoS One. 2012; 7(5):e38171. PMID: 22675445.
      Citations: 25     Fields:    Translation:Cells
    65. Rodriguez AR, Yu JJ, Guentzel MN, Navara CS, Klose KE, Forsthuber TG, Chambers JP, Berton MT, Arulanandam BP. Mast cell TLR2 signaling is crucial for effective killing of Francisella tularensis. J Immunol. 2012 Jun 01; 188(11):5604-11. PMID: 22529298.
      Citations: 9     Fields:    Translation:AnimalsCells
    66. Sanapala S, Yu JJ, Murthy AK, Li W, Guentzel MN, Chambers JP, Klose KE, Arulanandam BP. Perforin- and granzyme-mediated cytotoxic effector functions are essential for protection against Francisella tularensis following vaccination by the defined F. tularensis subsp. novicida ?fopC vaccine strain. Infect Immun. 2012 Jun; 80(6):2177-85. PMID: 22493083.
      Citations: 5     Fields:    Translation:AnimalsCellsPHPublic Health
    67. Maredia R, Devineni N, Lentz P, Dallo SF, Yu J, Guentzel N, Chambers J, Arulanandam B, Haskins WE, Weitao T. Vesiculation from Pseudomonas aeruginosa under SOS. ScientificWorldJournal. 2012; 2012:402919. PMID: 22448133.
      Citations: 27     Fields:    Translation:AnimalsCells
    68. Yin X, Feng Y, Lu Y, Chambers JR, Gong J, Gyles CL. Adherence and associated virulence gene expression in acid-treated Escherichia coli O157 : H7 in vitro and in ligated pig intestine. Microbiology. 2012 Apr; 158(Pt 4):1084-1093. PMID: 22301912.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    69. Chambers JP, Yu JJ, Jupelli M, Weintraub ST, Lopez-Ribot JL, Valdes JJ, Arulanandam BP. Alpha-1 antitrypsin is markedly decreased following pulmonary F. tularensis challenge. Front Cell Infect Microbiol. 2011; 1:20. PMID: 22919586.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    70. Ueda M, Ageyama N, Nakamura S, Nakamura M, Chambers JK, Misumi Y, Mizuguchi M, Shinriki S, Kawahara S, Tasaki M, Jono H, Obayashi K, Sasaki E, Une Y, Ando Y. Aged vervet monkeys developing transthyretin amyloidosis with the human disease-causing Ile122 allele: a valid pathological model of the human disease. Lab Invest. 2012 Mar; 92(3):474-84. PMID: 22184092.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    71. Li W, Murthy AK, Chaganty BK, Guentzel MN, Seshu J, Chambers JP, Zhong G, Arulanandam BP. Immunization with dendritic cells pulsed ex vivo with recombinant chlamydial protease-like activity factor induces protective immunity against genital chlamydiamuridarum challenge. Front Immunol. 2011; 2:73. PMID: 22566862.
      Citations: 4     Fields:    
    72. Aihara N, Chambers JK, Hosono K, Kamiie J, Shirota K. An experimental type II mixed cryoglobulinemia with renal glomerulopathy in ICR mice triggered by Capillaria hepatica infection. Histol Histopathol. 2011 12; 26(12):1519-29. PMID: 21972091.
      Citations: 1     Fields:    Translation:AnimalsCells
    73. Mutsuga M, Chambers JK, Uchida K, Tei M, Makibuchi T, Mizorogi T, Takashima A, Nakayama H. Binding of curcumin to senile plaques and cerebral amyloid angiopathy in the aged brain of various animals and to neurofibrillary tangles in Alzheimer's brain. J Vet Med Sci. 2012 Jan; 74(1):51-7. PMID: 21891973.
      Citations: 16     Fields:    Translation:HumansAnimalsCells
    74. Chambers JA. The rise of Chinese military medicine: opportunity for mercy ship, not gunboat, diplomacy. Mil Med. 2011 Sep; 176(9):1043-50. PMID: 21987964.
      Citations:    Fields:    Translation:Humans
    75. Serizawa S, Chambers JK, Une Y. Beta amyloid deposition and neurofibrillary tangles spontaneously occur in the brains of captive cheetahs (Acinonyx jubatus). Vet Pathol. 2012 Mar; 49(2):304-12. PMID: 21712514.
      Citations: 5     Fields:    Translation:AnimalsCells
    76. Chambers JK, Mutsuga M, Uchida K, Nakayama H. Characterization of AßpN3 deposition in the brains of dogs of various ages and other animal species. Amyloid. 2011 Jun; 18(2):63-71. PMID: 21557687.
      Citations: 7     Fields:    Translation:HumansAnimals
    77. Thathiah P, Sanapala S, Rodriguez AR, Yu JJ, Murthy AK, Guentzel MN, Forsthuber TG, Chambers JP, Arulanandam BP. Non-FceR bearing mast cells secrete sufficient interleukin-4 to control Francisella tularensis replication within macrophages. Cytokine. 2011 Aug; 55(2):211-20. PMID: 21565523.
      Citations: 3     Fields:    Translation:AnimalsCells
    78. King MD, Guentzel MN, Arulanandam BP, Bodour AA, Brahmakshatriya V, Lupiani B, Chambers JP. Effects of bacterial microflora of the lower digestive tract of free-range waterfowl on influenza virus activation. Appl Environ Microbiol. 2011 Jun; 77(12):4119-25. PMID: 21531837.
      Citations:    Fields:    Translation:AnimalsCells
    79. Yin X, Feng Y, Wheatcroft R, Chambers J, Gong J, Gyles CL. Adherence of Escherichia coli O157:H7 to epithelial cells in vitro and in pig gut loops is affected by bacterial culture conditions. Can J Vet Res. 2011 Apr; 75(2):81-8. PMID: 21731177.
      Citations: 7     Fields:    Translation:AnimalsCells
    80. Nallaparaju KC, Yu JJ, Rodriguez SA, Zogaj X, Manam S, Guentzel MN, Seshu J, Murthy AK, Chambers JP, Klose KE, Arulanandam BP. Evasion of IFN-? signaling by Francisella novicida is dependent upon Francisella outer membrane protein C. PLoS One. 2011 Mar 31; 6(3):e18201. PMID: 21483828.
      Citations: 13     Fields:    Translation:AnimalsCells
    81. Yin X, Zhu J, Feng Y, Chambers JR, Gong J, Gyles CL. Differential gene expression and adherence of Escherichia coli O157:H7 in vitro and in ligated pig intestines. PLoS One. 2011 Feb 28; 6(2):e17424. PMID: 21387009.
      Citations: 8     Fields:    Translation:AnimalsCells
    82. Rodriguez AR, Yu JJ, Murthy AK, Guentzel MN, Klose KE, Forsthuber TG, Chambers JP, Berton MT, Arulanandam BP. Mast cell/IL-4 control of Francisella tularensis replication and host cell death is associated with increased ATP production and phagosomal acidification. Mucosal Immunol. 2011 Mar; 4(2):217-26. PMID: 20861832.
      Citations: 15     Fields:    Translation:AnimalsCells
    83. Li W, Murthy AK, Guentzel MN, Chambers JP, Forsthuber TG, Seshu J, Zhong G, Arulanandam BP. Immunization with a combination of integral chlamydial antigens and a defined secreted protein induces robust immunity against genital chlamydial challenge. Infect Immun. 2010 Sep; 78(9):3942-9. PMID: 20605976.
      Citations: 10     Fields:    Translation:AnimalsCellsPHPublic Health
    84. Jupelli M, Selby DM, Guentzel MN, Chambers JP, Forsthuber TG, Zhong G, Murthy AK, Arulanandam BP. The contribution of interleukin-12/interferon-gamma axis in protection against neonatal pulmonary Chlamydia muridarum challenge. J Interferon Cytokine Res. 2010 Jun; 30(6):407-15. PMID: 20187773.
      Citations: 7     Fields:    Translation:AnimalsCells
    85. Liu B, Yin X, Feng Y, Chambers JR, Guo A, Gong J, Zhu J, Gyles CL. Verotoxin 2 enhances adherence of enterohemorrhagic Escherichia coli O157:H7 to intestinal epithelial cells and expression of {beta}1-integrin by IPEC-J2 cells. Appl Environ Microbiol. 2010 Jul; 76(13):4461-8. PMID: 20453145.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    86. Chaganty BK, Murthy AK, Evani SJ, Li W, Guentzel MN, Chambers JP, Zhong G, Arulanandam BP. Heat denatured enzymatically inactive recombinant chlamydial protease-like activity factor induces robust protective immunity against genital chlamydial challenge. Vaccine. 2010 Mar 08; 28(11):2323-9. PMID: 20056182.
      Citations: 12     Fields:    Translation:AnimalsCells
    87. Yu JJ, Goluguri T, Guentzel MN, Chambers JP, Murthy AK, Klose KE, Forsthuber TG, Arulanandam BP. Francisella tularensis T-cell antigen identification using humanized HLA-DR4 transgenic mice. Clin Vaccine Immunol. 2010 Feb; 17(2):215-22. PMID: 20016043.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    88. Yin X, Wheatcroft R, Chambers JR, Liu B, Zhu J, Gyles CL. Contributions of O island 48 to adherence of enterohemorrhagic Escherichia coli O157:H7 to epithelial cells in vitro and in ligated pig ileal loops. Appl Environ Microbiol. 2009 Sep; 75(18):5779-86. PMID: 19633120.
      Citations: 22     Fields:    Translation:HumansAnimalsCells
    89. King MD, Guentzel MN, Arulanandam BP, Lupiani B, Chambers JP. Proteolytic bacteria in the lower digestive tract of poultry may affect avian influenza virus pathogenicity. Poult Sci. 2009 Jul; 88(7):1388-93. PMID: 19531708.
      Citations: 1     Fields:    Translation:AnimalsCells
    90. Yin X, Chambers JR, Wheatcroft R, Johnson RP, Zhu J, Liu B, Gyles CL. Adherence of Escherichia coli O157:H7 mutants in vitro and in ligated pig intestines. Appl Environ Microbiol. 2009 Aug; 75(15):4975-83. PMID: 19525268.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    91. Murthy AK, Chaganty BK, Li W, Guentzel MN, Chambers JP, Seshu J, Zhong G, Arulanandam BP. A limited role for antibody in protective immunity induced by rCPAF and CpG vaccination against primary genital Chlamydia muridarum challenge. FEMS Immunol Med Microbiol. 2009 Mar; 55(2):271-9. PMID: 19281569.
      Citations: 17     Fields:    Translation:AnimalsCells
    92. Akbari MR, Haghighi HR, Chambers JR, Brisbin J, Read LR, Sharif S. Expression of antimicrobial peptides in cecal tonsils of chickens treated with probiotics and infected with Salmonella enterica serovar typhimurium. Clin Vaccine Immunol. 2008 Nov; 15(11):1689-93. PMID: 18827189.
      Citations: 10     Fields:    Translation:AnimalsCells
    93. Chambers JP, Arulanandam BP, Matta LL, Weis A, Valdes JJ. Biosensor recognition elements. Curr Issues Mol Biol. 2008; 10(1-2):1-12. PMID: 18525101.
      Citations: 23     Fields:    Translation:Animals
    94. Daum LT, Canas LC, Arulanandam BP, Niemeyer D, Valdes JJ, Chambers JP. Real-time RT-PCR assays for type and subtype detection of influenza A and B viruses. Influenza Other Respir Viruses. 2007 Jul; 1(4):167-75. PMID: 19432632.
      Citations: 8     Fields:    Translation:HumansCells
    95. Haghighi HR, Abdul-Careem MF, Dara RA, Chambers JR, Sharif S. Cytokine gene expression in chicken cecal tonsils following treatment with probiotics and Salmonella infection. Vet Microbiol. 2008 Jan 01; 126(1-3):225-33. PMID: 17681719.
      Citations: 11     Fields:    Translation:AnimalsCells
    96. Murthy AK, Chambers JP, Meier PA, Zhong G, Arulanandam BP. Intranasal vaccination with a secreted chlamydial protein enhances resolution of genital Chlamydia muridarum infection, protects against oviduct pathology, and is highly dependent upon endogenous gamma interferon production. Infect Immun. 2007 Feb; 75(2):666-76. PMID: 17118987.
      Citations: 57     Fields:    Translation:AnimalsCellsPHPublic Health
    97. Haghighi HR, Gong J, Gyles CL, Hayes MA, Zhou H, Sanei B, Chambers JR, Sharif S. Probiotics stimulate production of natural antibodies in chickens. Clin Vaccine Immunol. 2006 Sep; 13(9):975-80. PMID: 16960107.
      Citations: 19     Fields:    Translation:Animals
    98. Chambers JJ, Banghart MR, Trauner D, Kramer RH. Light-induced depolarization of neurons using a modified Shaker K(+) channel and a molecular photoswitch. J Neurophysiol. 2006 Nov; 96(5):2792-6. PMID: 16870840.
      Citations: 22     Fields:    Translation:AnimalsCells
    99. Rodriguez JD, Royall D, Daum LT, Kagan-Hallet K, Chambers JP. Amplification of Herpes simplex type 1 and Human Herpes type 5 viral DNA from formalin-fixed Alzheimer brain tissue. Neurosci Lett. 2005 Dec 16; 390(1):37-41. PMID: 16118038.
      Citations: 5     Fields:    Translation:HumansCells
    100. Haghighi HR, Gong J, Gyles CL, Hayes MA, Sanei B, Parvizi P, Gisavi H, Chambers JR, Sharif S. Modulation of antibody-mediated immune response by probiotics in chickens. Clin Diagn Lab Immunol. 2005 Dec; 12(12):1387-92. PMID: 16339061.
      Citations: 18     Fields:    Translation:AnimalsCells
    101. Hybarger G, Bynum J, Williams RF, Valdes JJ, Chambers JP. A microfluidic SELEX prototype. Anal Bioanal Chem. 2006 Jan; 384(1):191-8. PMID: 16315013.
      Citations: 14     Fields:    
    102. Yin X, Chambers JR, Barlow K, Park AS, Wheatcroft R. The gene encoding xylulose-5-phosphate/fructose-6-phosphate phosphoketolase (xfp) is conserved among Bifidobacterium species within a more variable region of the genome and both are useful for strain identification. FEMS Microbiol Lett. 2005 May 15; 246(2):251-7. PMID: 15899413.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    103. Moore DJ, Chambers JK, Murdock PR, Emson PC. Human Ntera-2/D1 neuronal progenitor cells endogenously express a functional P2Y1 receptor. Neuropharmacology. 2002 Nov; 43(6):966-78. PMID: 12423666.
      Citations: 4     Fields:    Translation:HumansCells
    104. Lafond S, Paré T, Dinel H, Schnitzer M, Chambers JR, Jaouich A. Composting duck excreta enriched wood shavings: C and N transformations and bacterial pathogen reductions. J Environ Sci Health B. 2002 Mar; 37(2):173-86. PMID: 11990371.
      Citations: 1     Fields:    Translation:AnimalsCellsPHPublic Health
    105. Gong J, Forster RJ, Yu H, Chambers JR, Sabour PM, Wheatcroft R, Chen S. Diversity and phylogenetic analysis of bacteria in the mucosa of chicken ceca and comparison with bacteria in the cecal lumen. FEMS Microbiol Lett. 2002 Feb 19; 208(1):1-7. PMID: 11934485.
      Citations: 31     Fields:    Translation:AnimalsCells
    106. Freeman K, Tsui P, Moore D, Emson PC, Vawter L, Naheed S, Lane P, Bawagan H, Herrity N, Murphy K, Sarau HM, Ames RS, Wilson S, Livi GP, Chambers JK. Cloning, pharmacology, and tissue distribution of G-protein-coupled receptor GPR105 (KIAA0001) rodent orthologs. Genomics. 2001 Dec; 78(3):124-8. PMID: 11735218.
      Citations: 18     Fields:    Translation:HumansAnimalsCells
    107. Moore DJ, Chambers JK, Wahlin JP, Tan KB, Moore GB, Jenkins O, Emson PC, Murdock PR. Expression pattern of human P2Y receptor subtypes: a quantitative reverse transcription-polymerase chain reaction study. Biochim Biophys Acta. 2001 Oct 31; 1521(1-3):107-19. PMID: 11690642.
      Citations: 42     Fields:    Translation:HumansCells
    108. Al-Barazanji KA, Miller JE, Rice SQ, Arch JR, Chambers JK. C-terminal fragments of ACTH stimulate feeding in fasted rats. Horm Metab Res. 2001 Aug; 33(8):480-5. PMID: 11544562.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    109. Muir AI, Chamberlain L, Elshourbagy NA, Michalovich D, Moore DJ, Calamari A, Szekeres PG, Sarau HM, Chambers JK, Murdock P, Steplewski K, Shabon U, Miller JE, Middleton SE, Darker JG, Larminie CG, Wilson S, Bergsma DJ, Emson P, Faull R, Philpott KL, Harrison DC. AXOR12, a novel human G protein-coupled receptor, activated by the peptide KiSS-1. J Biol Chem. 2001 Aug 03; 276(31):28969-75. PMID: 11387329.
      Citations: 189     Fields:    Translation:HumansAnimalsCells
    110. Patel L, Charlton SJ, Chambers JK, Macphee CH. Expression and functional analysis of chemokine receptors in human peripheral blood leukocyte populations. Cytokine. 2001 Apr 07; 14(1):27-36. PMID: 11298490.
      Citations: 12     Fields:    Translation:HumansCells
    111. Hill J, Duckworth M, Murdock P, Rennie G, Sabido-David C, Ames RS, Szekeres P, Wilson S, Bergsma DJ, Gloger IS, Levy DS, Chambers JK, Muir AI. Molecular cloning and functional characterization of MCH2, a novel human MCH receptor. J Biol Chem. 2001 Jun 08; 276(23):20125-9. PMID: 11274220.
      Citations: 33     Fields:    Translation:HumansCells
    112. Langmead CJ, Szekeres PG, Chambers JK, Ratcliffe SJ, Jones DN, Hirst WD, Price GW, Herdon HJ. Characterization of the binding of [(125)I]-human prolactin releasing peptide (PrRP) to GPR10, a novel G protein coupled receptor. Br J Pharmacol. 2000 Oct; 131(4):683-8. PMID: 11030716.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    113. Elshourbagy NA, Ames RS, Fitzgerald LR, Foley JJ, Chambers JK, Szekeres PG, Evans NA, Schmidt DB, Buckley PT, Dytko GM, Murdock PR, Milligan G, Groarke DA, Tan KB, Shabon U, Nuthulaganti P, Wang DY, Wilson S, Bergsma DJ, Sarau HM. Receptor for the pain modulatory neuropeptides FF and AF is an orphan G protein-coupled receptor. J Biol Chem. 2000 Aug 25; 275(34):25965-71. PMID: 10851242.
      Citations: 23     Fields:    Translation:HumansCells
    114. Szekeres PG, Muir AI, Spinage LD, Miller JE, Butler SI, Smith A, Rennie GI, Murdock PR, Fitzgerald LR, Wu Hl, McMillan LJ, Guerrera S, Vawter L, Elshourbagy NA, Mooney JL, Bergsma DJ, Wilson S, Chambers JK. Neuromedin U is a potent agonist at the orphan G protein-coupled receptor FM3. J Biol Chem. 2000 Jul 07; 275(27):20247-50. PMID: 10811630.
      Citations: 20     Fields:    Translation:HumansCells
    115. Iqbal SS, Chambers JP, Goode MT, Valdes JJ, Brubaker RR. Detection of Yersinia pestis by pesticin fluorogenic probe-coupled PCR. Mol Cell Probes. 2000 Apr; 14(2):109-14. PMID: 10799272.
      Citations: 6     Fields:    Translation:CellsPHPublic Health
    116. Smart D, Gunthorpe MJ, Jerman JC, Nasir S, Gray J, Muir AI, Chambers JK, Randall AD, Davis JB. The endogenous lipid anandamide is a full agonist at the human vanilloid receptor (hVR1). Br J Pharmacol. 2000 Jan; 129(2):227-30. PMID: 10694225.
      Citations: 179     Fields:    Translation:HumansCells
    117. Ames RS, Sarau HM, Chambers JK, Willette RN, Aiyar NV, Romanic AM, Louden CS, Foley JJ, Sauermelch CF, Coatney RW, Ao Z, Disa J, Holmes SD, Stadel JM, Martin JD, Liu WS, Glover GI, Wilson S, McNulty DE, Ellis CE, Elshourbagy NA, Shabon U, Trill JJ, Hay DW, Ohlstein EH, Bergsma DJ, Douglas SA. Human urotensin-II is a potent vasoconstrictor and agonist for the orphan receptor GPR14. Nature. 1999 Sep 16; 401(6750):282-6. PMID: 10499587.
      Citations: 137     Fields:    Translation:HumansAnimalsCells
    118. Iqbal SS, Chambers JP, Brubaker RR, Goode MT, Valdes JJ. Detection of Yersinia pestis using branched DNA. Mol Cell Probes. 1999 Aug; 13(4):315-20. PMID: 10441205.
      Citations: 1     Fields:    Translation:Cells
    119. Colston JT, Valdes JJ, Chambers JP. Ca2+ channel alpha 1-subunit transcripts are differentially expressed in rat pheochromocytoma (PC12) cells following nerve growth factor treatment. Int J Dev Neurosci. 1998 Aug; 16(5):379-89. PMID: 9829174.
      Citations: 5     Fields:    Translation:AnimalsCells
    120. Kopec K, Chambers JP. Effect of Alzheimer's brain extracts on dynein immunoreactivity in PC12 cells. Proc Soc Exp Biol Med. 1997 Dec; 216(3):429-37. PMID: 9402150.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    121. Kumar P, Colston JT, Chambers JP, Rael ED, Valdes JJ. Detection of botulinum toxin using an evanescent wave immunosensor. Biosens Bioelectron. 1994; 9(1):57-63. PMID: 8166958.
      Citations: 3     Fields:    
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